Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI424938:459-6855[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 4.1 2.4e+02 2.2 2.1 1 15 48 62 48 65 0.83

2 26 0.00043 0.025 14.7 1.0 2 23 340 361 339 361 0.97

3 26 5.9e-06 0.00034 20.6 0.7 2 23 368 389 367 389 0.97

4 26 0.24 14 6.1 2.9 1 23 399 421 399 421 0.96

5 26 1.5 88 3.6 0.0 3 23 446 473 444 473 0.83

6 26 2.2 1.3e+02 3.0 0.9 2 23 480 501 479 501 0.71

7 26 5.9e-06 0.00034 20.6 1.6 3 23 541 562 539 562 0.96

8 26 0.14 8.3 6.8 3.7 3 23 569 589 567 589 0.94

9 26 4.2e-05 0.0025 17.9 2.2 1 23 594 616 594 616 0.94

10 26 0.0026 0.15 12.3 0.2 2 23 625 647 624 647 0.97

11 26 0.00098 0.057 13.6 0.8 2 20 654 672 653 674 0.94

12 26 9.4e-05 0.0055 16.8 0.4 1 23 685 707 685 707 0.99

13 26 0.001 0.058 13.6 2.6 1 23 713 736 713 736 0.98

14 26 0.0015 0.084 13.1 2.9 2 23 1063 1084 1062 1084 0.97

15 26 0.0022 0.13 12.5 2.7 2 23 1091 1112 1090 1112 0.98

16 26 0.077 4.5 7.6 1.2 1 23 1122 1144 1122 1144 0.96

17 26 1.4 83 3.6 0.1 3 23 1169 1196 1167 1196 0.84

18 26 1.4 81 3.7 1.1 2 23 1203 1224 1202 1224 0.82

19 26 1.9 1.1e+02 3.3 0.3 1 23 1230 1250 1230 1250 0.83

20 26 0.0001 0.0061 16.7 0.2 1 20 1262 1281 1262 1282 0.97

21 26 0.0029 0.17 12.1 0.8 2 23 1291 1312 1290 1312 0.97

22 26 0.0001 0.0061 16.6 0.4 2 23 1318 1339 1317 1339 0.93

23 26 0.77 45 4.5 1.3 3 23 1349 1369 1347 1369 0.94

24 26 0.00074 0.043 14.0 1.3 3 21 1377 1395 1375 1396 0.94

25 26 0.0028 0.16 12.1 3.1 1 23 1407 1429 1407 1429 0.98

26 26 0.00083 0.048 13.8 2.5 1 23 1435 1458 1435 1458 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	4.1	2.4e+02	2.2	2.1	1	15	48	62	48	65	0.83
2	26	0.00043	0.025	14.7	1.0	2	23	340	361	339	361	0.97
3	26	5.9e-06	0.00034	20.6	0.7	2	23	368	389	367	389	0.97
4	26	0.24	14	6.1	2.9	1	23	399	421	399	421	0.96
5	26	1.5	88	3.6	0.0	3	23	446	473	444	473	0.83
6	26	2.2	1.3e+02	3.0	0.9	2	23	480	501	479	501	0.71
7	26	5.9e-06	0.00034	20.6	1.6	3	23	541	562	539	562	0.96
8	26	0.14	8.3	6.8	3.7	3	23	569	589	567	589	0.94
9	26	4.2e-05	0.0025	17.9	2.2	1	23	594	616	594	616	0.94
10	26	0.0026	0.15	12.3	0.2	2	23	625	647	624	647	0.97
11	26	0.00098	0.057	13.6	0.8	2	20	654	672	653	674	0.94
12	26	9.4e-05	0.0055	16.8	0.4	1	23	685	707	685	707	0.99
13	26	0.001	0.058	13.6	2.6	1	23	713	736	713	736	0.98
14	26	0.0015	0.084	13.1	2.9	2	23	1063	1084	1062	1084	0.97
15	26	0.0022	0.13	12.5	2.7	2	23	1091	1112	1090	1112	0.98
16	26	0.077	4.5	7.6	1.2	1	23	1122	1144	1122	1144	0.96
17	26	1.4	83	3.6	0.1	3	23	1169	1196	1167	1196	0.84
18	26	1.4	81	3.7	1.1	2	23	1203	1224	1202	1224	0.82
19	26	1.9	1.1e+02	3.3	0.3	1	23	1230	1250	1230	1250	0.83
20	26	0.0001	0.0061	16.7	0.2	1	20	1262	1281	1262	1282	0.97
21	26	0.0029	0.17	12.1	0.8	2	23	1291	1312	1290	1312	0.97
22	26	0.0001	0.0061	16.6	0.4	2	23	1318	1339	1317	1339	0.93
23	26	0.77	45	4.5	1.3	3	23	1349	1369	1347	1369	0.94
24	26	0.00074	0.043	14.0	1.3	3	21	1377	1395	1375	1396	0.94
25	26	0.0028	0.16	12.1	3.1	1	23	1407	1429	1407	1429	0.98
26	26	0.00083	0.048	13.8	2.5	1	23	1435	1458	1435	1458	0.98

Sequence Information

Coding Sequence: ATGGAGCAATTCGTGAATTGTGTGCTATGCCTGACTACCGAGCCCGAAAGCTTCCTCAAAGTGTTCTCTGACGAAAAGCAAAGCGTCGATATAGCGGGAGTCATCACAAAACATCTTTGGCTAAAACCGTCCAACGATTCTTACGTTTGCAATGAATGTTGGAAGTGTTTAAACGATTTCCATGAGTTTTACAACAAGCTAGAGGCCATACACTATCCCCCGGATCCTGACGATCCGTCATGTAACGCAAAAGACATCAGACAGTATCTATTCGAATTTCATCCTGTGGAAGATGTGAAAATAGAAGAATTATCCCAAGACGCAGAACAGTTGGAAGAAATCGAGTATGAATATTTGGAGGACTGTAACGATGAAAGTGTAGAAAATGATACGAAGGATCGGATTAGCAGCAGTCGCCCCAAAAGAGCCAGTGCTGCACAGCCAAGCTATAAACTGGATGCGGCCGATGCAGAATGGGAAAAGGATTATCTAGCAACTAACGAAGAGGATTACGAGGAAGACGAAAACGATGAAGATTACGATGCAGACATGAAAGACGACGTAGACTATCTGGAAGCGGATAATGACGATAGTGAAGTTGTGGACTACGACAAACAGGACTCAAAATCCGACGTAATCATAAAAAAGGAATCGATTACACCGGTGAAAAGGGGTAGAGGCCGGCCACCGAAAGTAAAAACGGAAGTAGTGGTAAGTAAACCGGAGCCGAGAAAGTTACGCCAACGTGGTCGCAGAAGGAAAGCATCCGCTACCAGCAGTGACTCGGAGTTGGAATCGGACTTTGACGATACAAACGACAGCGACGATTGGAAAAAGTATGGCAATACGTCGaaaaaaaaGACGAGAAAGTCGCTTGGCTTCCGGCAGCTGCAAGAAAAGATATTTTCATACGTGGATGAATTTATCTGCTACTATTGCCCGGAGAAGGTTGTTTTTGAACGTTTCCATCATGCGAATCTCCACTACAAGAAAGTACACAACGAGCCAGCCTTTCTAAGGTGCCCAAAGTGTGGCCGAAAATGTTTCACGCCTGGTGGTTTTGTGAGTCACATGGAAACTCACGAAGATCCGGATCGAAATAAATGCAACATTTGCGGTAAGGTGACGGATCAGCAAATCACCCTTAAGAAGCATATGCGGGCACATCAGGATAAACTCGAGAAGGATTTCCCGTACCCGTGTAGTCAGTGCACACGACGGTTCGAGCATGAAGAAAAACGTGACAAACATGAACGTTTGCACGGCCGTAAAGTAATCATCAAGAAGGAGAAGGGTCGGGATCTGGAGCTGCTTGAATTCTACAAACGCATCTATTGCGATATATGCGAAGAAAAGAGTCCCGAATCGACCTCGTTCGATAACTTTTGGGATTTGAAGGTGCACATGAGCGGGGAGCACAATAAAACGCCCTACCTAAAGTGCCCGATGTGTGGCAAAAAGAATGCCTGCCGGCAGCAGCTAATGGTACACGTCGATGTACATAATAACCCGGAACACTATCGGTGTGAAGTATGTAAAGAAATTCATCAAAATTTGGACAAACACATGATCAAGGCACATACACCGGAAACGTTGTTACCGGATGAGAAAAATTACGGCTGCGAACATTGTGGCAAAATGTTCAAATATCAAACCAACCTCCGAAGTCACATCGATCGTGTGCACGGTGTAAAGGATGTATGCTGTGACATCTGCAAAAAATACTTCAATCACAAAGCTCTAAGTGCCCACAAACGTTCGGCACACACTGACGAGATGTTTATGTGCGAACATTGCCCGAAAATGTTCAAAACGCGCAGCGGGCTTGAATCGCACAAGAGCGATCACGACGAAACGTTGCGCAAATCGGTCAAGTGTACCATATGTGGTAAGGAAATGCGGCGCGGTGCCAGCATGGCGAAGCACATGAAAACGATACACTCACAGGAAGATCCGGTCAAGTGCGATCTGTGTGGTAAGATGTTCCGCACCACGTTCCACATGTTGCGTCATCGGGCAAACACGTGCTCCGCCACAATCGACTCGCGCCCGTACAAATGTGAAGTTTGTGGCAAAGGTTTCGCTATGAAGCTTACGATGACCGAGCACATGACGACGCATACGCGCACCAGCTTGTACCAGTGCGCATTTTGCTTTAAAACGTTTGGATACATTTCGAATCTGTATAAGCATAGGAAAAAGGCGCATCCACTCGAGTGGCAGGAGGTACAGGCAAGACCCGAACAAGGGATTGCCACCTATTTGTACAACATTGGGCACGATATCATAATGGAGCATAAGAACAGTTGTGCGCTTTGTTTAGTGTCCGAATCGAAGTGCTTTATTGAAGTGTTTAGTGATGCCAACAGTGAACTGAATATGGCTTCGATCATATCAAAGCATCTATGGTTTCATACCGACTCGTCCAACAAAAGTGCAAAGAAACATTTTGTCGAAGTGATAGATTATTCTAGCAATGATGAAGATTTGGATGACTACCAGTCTGATGACAATATGCTCGAACATAATGATTCATTAAGCATCGAGTATGAGGATAAATCGGAAGGGTTAGTGAAAATTGAACCATTGGATGTCAGAGTACTTGACGAACAGCCAGCAAAACGGCGAAGAGGTCGTCCATCCAACACGAATCGTGTGCAGGACGCGAGCACAAAGGAAATATGTGCAGTTGTCCCGAATGACATGCCTAAACGACCCCGGGGTCGTCCTCCGAAGCAAAAACCCATCGTACAAAGTTCGGAAGAGAATGCAGTCAAAGAGACGAAGGCATCAAACCAAGCATCCACCGTGCAAGGTCCTATTAAACGTGGCAGAGGTCGGCCACCTAAAAAAGCGCTAGAAGCCGCTAACTCAACATCCTCTGCAGCTCTACATACCGATGGAAAACAATCGGACACGATAGTGGAGAGCCCTAAAAGAAGAACACCCCGTGCGCGAAAATCGAAATACGAAAGCGAAAGTGAGCAAGAAGTATATTCGGACTACGAAGATTCACAGCATAAGCAGAAACCCGCAGGGAAGCGCATTCGCAATGATCGGGATGAGCGAATATTTAAGTATGTGCAAGAATTTTGCTGCCACTACTGCGTGGACCACGTGTCTTTCAAACGATTTATCGATGCGGATCGACACTACAAGCTGGTGCACAATGAGCCTGGCTTTTTGAAGTGTACAAAATGTGATAAGAAATGTTTCACACCCGGCATGTTCGTAAGCCACATGGAAACACACGAAGACCCAGAGAAAAATAAATGCAACATTTGTGGAAAAATGACCGACTGTAATATTTCGCTCAAGAAGCATATGCGAGTGCATCTCAGCCAACTGGAGGAGAACCTACCGTTTCCCTGCAGCCGCTGCAAACGAAAATTCGAATCGGAAGAGCTGCGAATCAAGCACGAAAAACTGCACGTACCAAAACCGCTCGTTAAGCGAGATAAGGGACCCGATTTGGAGCTACTTGCCTTCTACAAACGCATCTATTGCGATATATGCGAGGAGCATGAGCCCGAAACCACCTCGTTCGAGAACTTCTGGGACCTACGGGTACACATGGAGCAGGAGCACAATAAGGGAGCATACCTAAAATGTCCAATATGTAACAAGAGGAATCTGTACCGGCAGCACTTGATCACGCACATAGATTTGCATAACAATCCTGAGAAGTATCGGTGTGAAGTTTGTAAAGAAATCTATCAAAACCTTGACTCGCACATGATAAAAGCGCATACACCGACCACGGCGATACCAGCGGATAAAAAGTACAAGTGTGACCAATGTGGCCGAATGTTCAACTTTTTGGCGAACTTGAAAATGCATATCGATTGTATTCACGGTTCCAAAGATGTTCGCTGCAACGTATGCGACAAATACTTTAATTTAAAGGCGTTCCGAGCGCACAAGCGAACAGCGCACACCGACCAGCTGCTAATGTGCGAGCACTGTCCGAAGATGTTCAAAACACGTGGTGCGCTGGAAGTACACAAAGGTATTCACGACGATAGCTTAGTGCAGTTTACTGCGTGCAAGTTATGCAACAAGCAAATACGGCTAACGAACGTAAAGAAGCACATGACATCGCAGCACTCTCAGGATGGACCGGTAAATTGCGAACTCTGCGGCAAAATATTCCGTACGATGTTCCACATGAAGCGTCACCAGAAGAACACGTGCGAGGCAACGATCAATTCGCGAAAGCACAAGTGTGAAGTGTGCGGCAAAGGTTTCTGTCTGAAGTTGACCATGATCGAGCATATGACGACGCATACTCGCTCTAATAAGTATCAATGTGCGTTCTGCTTCAAATCGTTTGGTTACATTTCTAATTTGTACAAACATCGCAAGAAGGCTCACCCGCTCGAATGGCAAGAGATACAGGCCCGTCCTGAGGAGGGCATATCGTCGGTCATTGTTGTGAGAAACTAA
Protein Sequence: MEQFVNCVLCLTTEPESFLKVFSDEKQSVDIAGVITKHLWLKPSNDSYVCNECWKCLNDFHEFYNKLEAIHYPPDPDDPSCNAKDIRQYLFEFHPVEDVKIEELSQDAEQLEEIEYEYLEDCNDESVENDTKDRISSSRPKRASAAQPSYKLDAADAEWEKDYLATNEEDYEEDENDEDYDADMKDDVDYLEADNDDSEVVDYDKQDSKSDVIIKKESITPVKRGRGRPPKVKTEVVVSKPEPRKLRQRGRRRKASATSSDSELESDFDDTNDSDDWKKYGNTSKKKTRKSLGFRQLQEKIFSYVDEFICYYCPEKVVFERFHHANLHYKKVHNEPAFLRCPKCGRKCFTPGGFVSHMETHEDPDRNKCNICGKVTDQQITLKKHMRAHQDKLEKDFPYPCSQCTRRFEHEEKRDKHERLHGRKVIIKKEKGRDLELLEFYKRIYCDICEEKSPESTSFDNFWDLKVHMSGEHNKTPYLKCPMCGKKNACRQQLMVHVDVHNNPEHYRCEVCKEIHQNLDKHMIKAHTPETLLPDEKNYGCEHCGKMFKYQTNLRSHIDRVHGVKDVCCDICKKYFNHKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKSDHDETLRKSVKCTICGKEMRRGASMAKHMKTIHSQEDPVKCDLCGKMFRTTFHMLRHRANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATYLYNIGHDIIMEHKNSCALCLVSESKCFIEVFSDANSELNMASIISKHLWFHTDSSNKSAKKHFVEVIDYSSNDEDLDDYQSDDNMLEHNDSLSIEYEDKSEGLVKIEPLDVRVLDEQPAKRRRGRPSNTNRVQDASTKEICAVVPNDMPKRPRGRPPKQKPIVQSSEENAVKETKASNQASTVQGPIKRGRGRPPKKALEAANSTSSAALHTDGKQSDTIVESPKRRTPRARKSKYESESEQEVYSDYEDSQHKQKPAGKRIRNDRDERIFKYVQEFCCHYCVDHVSFKRFIDADRHYKLVHNEPGFLKCTKCDKKCFTPGMFVSHMETHEDPEKNKCNICGKMTDCNISLKKHMRVHLSQLEENLPFPCSRCKRKFESEELRIKHEKLHVPKPLVKRDKGPDLELLAFYKRIYCDICEEHEPETTSFENFWDLRVHMEQEHNKGAYLKCPICNKRNLYRQHLITHIDLHNNPEKYRCEVCKEIYQNLDSHMIKAHTPTTAIPADKKYKCDQCGRMFNFLANLKMHIDCIHGSKDVRCNVCDKYFNLKAFRAHKRTAHTDQLLMCEHCPKMFKTRGALEVHKGIHDDSLVQFTACKLCNKQIRLTNVKKHMTSQHSQDGPVNCELCGKIFRTMFHMKRHQKNTCEATINSRKHKCEVCGKGFCLKLTMIEHMTTHTRSNKYQCAFCFKSFGYISNLYKHRKKAHPLEWQEIQARPEEGISSVIVVRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -