Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: AXCM01009011:6052-10713[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 6.3e-05 0.0036 17.4 1.1 1 23 254 276 254 276 0.97

2 15 0.00066 0.038 14.1 0.9 1 23 282 304 282 304 0.97

3 15 5.3e-05 0.0031 17.6 0.2 1 23 499 521 499 521 0.98

4 15 4.7e-06 0.00027 20.9 1.4 1 23 527 550 527 550 0.98

5 15 0.32 19 5.7 2.0 1 23 592 615 592 615 0.94

6 15 0.64 37 4.7 0.1 2 23 690 711 689 711 0.95

7 15 2.5 1.4e+02 2.9 0.4 1 21 717 737 717 740 0.75

8 15 0.003 0.18 12.1 0.8 2 19 748 765 747 766 0.95

9 15 0.0057 0.33 11.2 8.4 1 23 775 797 775 797 0.97

10 15 0.019 1.1 9.6 0.9 2 23 803 824 802 824 0.97

11 15 1.2e-06 6.9e-05 22.8 1.3 1 23 830 852 830 852 0.98

12 15 0.00022 0.013 15.6 0.1 1 23 858 880 858 880 0.97

13 15 2.6e-05 0.0015 18.5 0.1 1 23 886 908 886 909 0.95

14 15 0.00047 0.027 14.6 0.1 1 23 923 945 923 945 0.98

15 15 0.016 0.92 9.8 0.2 1 20 1499 1518 1499 1521 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	6.3e-05	0.0036	17.4	1.1	1	23	254	276	254	276	0.97
2	15	0.00066	0.038	14.1	0.9	1	23	282	304	282	304	0.97
3	15	5.3e-05	0.0031	17.6	0.2	1	23	499	521	499	521	0.98
4	15	4.7e-06	0.00027	20.9	1.4	1	23	527	550	527	550	0.98
5	15	0.32	19	5.7	2.0	1	23	592	615	592	615	0.94
6	15	0.64	37	4.7	0.1	2	23	690	711	689	711	0.95
7	15	2.5	1.4e+02	2.9	0.4	1	21	717	737	717	740	0.75
8	15	0.003	0.18	12.1	0.8	2	19	748	765	747	766	0.95
9	15	0.0057	0.33	11.2	8.4	1	23	775	797	775	797	0.97
10	15	0.019	1.1	9.6	0.9	2	23	803	824	802	824	0.97
11	15	1.2e-06	6.9e-05	22.8	1.3	1	23	830	852	830	852	0.98
12	15	0.00022	0.013	15.6	0.1	1	23	858	880	858	880	0.97
13	15	2.6e-05	0.0015	18.5	0.1	1	23	886	908	886	909	0.95
14	15	0.00047	0.027	14.6	0.1	1	23	923	945	923	945	0.98
15	15	0.016	0.92	9.8	0.2	1	20	1499	1518	1499	1521	0.94

Sequence Information

Coding Sequence: ATGAACCACAACGCATTCCCGGTTTGGCAAGTGGCGGCAAGCGAGCAGCAGACAACACGGGGCAGCACCACCGGCACCCAAAACAATGGTGGAAGCATTTCAACACTGAAGTATGTCACAAATGCACGGCCAAATGTGAAGATTATAAGCATCCCCGGTCGGGTCGGTGCCGGGAGCAATAACACCGACGGCACGCTGTTGTACGAAACGTCGTTTGATGGTTCATACTTGACCGTGACAAAAGATCACCACCATCAGCAGCAACAGCAACCGCTTCGGCGATCAACGCCCAACCATGGCGTTGCTATGTTGAACGATTCCATTCTACTTCAAACGCCCGACGGCCAGGGCTACCACCTCGTAGACGAACGATCGATACAGAACATTGATCAAATTCCGCCGGAAAATTTAATCTACATGACATCCTCCGAGGTGTCGCCGTTGGTGTCAGATGTTGATAAAATAAATCCCCTTACGGTCCCTTGCTTATCAACGTCAAGTGAACAAAATCAGCTGGAACTGGGTGATTACGTTGATTCCGGGCCAGCATCGGAAGCCGTAGATGAAACGCCCCAACTACAGACGGATTACGCCGAAGAGTGTCAAGTGACGGAGGAAGTAATAACGGATGATTGGGTACAGTCGCAGGGTGAGGAGTGCGTGCAGGTGACGGTTGATCAGCTCGGTGTGAATACGATCGCGGTGGAAGATGAAATTCCGGTTCCGCTCGATCAGGACCAGTACACACTATCCCGGCCGTATCCGTGCGATTTCTGCAGCCGACGGTTTCGCAAGAAGGCTAGCCTGCAGAATCACCTAATGGCACATTCGAACGATCGACCGCATATGTGCAATCTGTGTGGTGCTCAGTACGGCCGACGGTCCGACCTAATCAATCATCTGAAGCAGCACGCGTACGCCGGTACCGAGCAAGATGATTTATCGCTTCGTGGCGATCAAGACGCCGATTATGATTTACCGGAACTTACAAATACGGCTGCCCATTTGAAACATCGTACGAGACATTCGAGTGAGGATGAAGATCTTTACATACAGAATGCGATGGTGAGCTACAATTCGCAACCTCCGATGCAGTTGATTTCGACCACGAATTATGGTTCATCTTCGGCGACGATTTCGTCTTCCTACGATCATAACGAAGCGATGGAACGCACGTCTTTCAGCAATGGACCAACGGAGatcgatcatcaatcatcgatcatcgatATTGGCTATCCAAGTCCAACCCTTCCCGCAATCAGTGCGGGAAAGCGAATGCCGCGCAAACGACAGATTCCTTCGTCGGATTTGAGAACAGCACGGACCAAGCCGGCACCATCGACCAAAACAACGACTCAGGTACGATCGAGTGGAGCATCACGCACCAGTGTGACCTCGAATCGACAAATTAAAAAAGAACCAATCGATAACTCTGAAGGCGATACAGTCCCAGCACCAGCGACGGTTTTCCCGGTAATCGACGAGCGCAAACCGTTCGTATGTCAACAGTGCGGTATATCGTTTGGAAGGGAAAAAGCACTGATGGCGCATTCGCGCACCCATGCAAACAGAGCGCATTATGAGTGTGATCATTGTTTTGCTACATTTAGCGATTGGTCACAGCTGCAGGAACACGTGCGTCGGACGCACCAGTTGCACAGCACCAAGAGCGAACCTCCTGCAAGCACCGAAAGCAAATCTGAATGGGTTCCGGATCATGAAACGACGTATGATCACGATTCCGGAGGTACGTCGGTAGATACCAAGAATCGATATAATTGTGATAAATGCAGTGCTGTTTTCTTCCAACTGGAACACATATTGAACCATAAGCAGCTAAAGCACGGTGTAACCGGTTCCGCTGTTGATGCATCGCCACAACGGAAGTTGGTCATAAAACAGGAGCGAACGACACACCACAACGTGGGTTACGATGATCTGGAACAGGACGTTACCGATCAGGAAATAGAGGAAGATGATTATGGCAATTTGGATTATTCGATCGAGCACTATGAGAGCCGTTCTAGCGATCCGGAAACAAACGCTCAACAGCCAACCATTGCGCTGACGTGTCGCGAGTGTGGCGACACGTTCGAGAACGGGATGGAACTGTTGGAACACTCCGAAACACACAACCGTTACGAACCGCACGAGTGTCAACTGTGCGGTGAAAAGTTTCTGGAGGAAGCCACCATTAAGCAGCACGTACAGGAACGCCACGGCAACGAGCTGACGACCACATCGTGTGCAATCTGTGGCAAACGGTGCAAAAGTCAAACGACGCTCATCAAGCATGCGTGGGATCATTCGCGGGAACGGACACACTCCTGTTCGCAGTGTGGCAAAACGTTCCACCACATGACGCGCCTCAAGCGCCACATGGAATCGCACCGAAACAAGACGGTCCGAtgtgaggtgtgcaaccaggaattccccgacggtcgaacgctcatgaaccatcgccattcgcacacgaagtcgaacgaatatccgtgccatgagtgtggcaaaacgtttggttcgcgatcttcgcaacagattcacatgcgtatacataccggcgagcggccctatgcttgccggtactgttggaaagcattcgccgacgggggtacactgcggaagcatgagcggattcatacgggagaaaaaccgtacgcatgtcccgtctgtcccaaggcgttcaatcaacgggtggtgctgcgtgaacacatccgtgcgcaTCATTCACAAGCTGACGCGAAGCGTGGTTCACCCAACCAGCCTTATTACTGCAGTGTGTGCAGTGCTCCGTTTTCAACCACGGATGATCTGGTGCAGCATTTGATTAAGCACAGCGACATGAACACGGCGATGAAGCGCGAACCACCAACCTTCCCGCGAAAGTACAAACGCCGTCGAAAGCTGAAACCACACGAACTGGAGCGGTTGCAGAGTGGGCGACGGAAGCAGAAAAACAAGCCCTCGGAAGAACTAGAAGATGATGGCGATGATGCTGGGTTCGAAGAAAGTGCCAGTGCTACGGAAAGTACCAAGCAGCAGCAATACGAACCTAAACCGTCGTTAGTTTTGTCCCATCCGGATGGGACGCTAAAGACTAAGCGGGAACTTAAACTCGAGTACGGACGGAGGGGTGAATCGCACGGCTCTAAACCATCCCTTTCGCCGAATGGAATGCTGGACGAAAACGGTATTAATCTGCTAAGCAATATCGTGCTGCTTCATGGAGAGCAAGATGATCCTTCAAACGCGGACAACGATAAGCTTTCCCGGGGAGCAAAGAAACCGGTGGAAACAACTCCGAAGGAAAAGGCCGGCCCTAGCAACTGTCGCCCATCAGCGAACGCGCCAAAATGGAATGCAACCCCGACGAGAAAAAAGCCATCCCGCAAACGTACGGCTTCTTTCGCTTCCGGAGATTCTTCGGAAGCGTTGGTAAAGGTAAAGGAGGAAGAACATTCTTCACCGCAAAGTGCTGGCAGCACCATCACGAACGTGATGGAAGCATTTTTCCGTACGCGGAAGCGGAACTCTTTGCTGCCGGAGATATCCTCGCACCGGATCTCTTCCGTAAGCTTTCCCTTGCTGGACGATGGAAACACAGACGATCCGATGGACGAGCCGATGGTGGATGACGGTTGCAGACGGGGATACGGACAGCACACGCCACAACAAACTCGCAAAAGTACTGCCTCCTTTAGTGCGTCGGAAGACGATCTGAACCATCAGCTGCTGATGGAAATATCGCACAAAAATAAGTACACGGATCGGTTCAACAGTGACACGGTGCACGATCTGCAAGAAATTCTACGGTCACCCATAAAGGGTGCTCCATCGAGGAACGAGCTGTCTACGCCATCGACCAAACGTGCCAACCCAAACAAGCAGGATGGGAAACCATCAGCACAACGCAAGCAGAAAGGAAAGTCTAAGGCAAAAAACAAGAAGACTGTTCCGGTCCGGCCACAACAAAAACCGGTCGAAAAGAAGATTAAGAAGGTGGCGCCAGAAACACCACCGGCTGTGTTGCGTAGCCAGAGGCTAACGCGTCGTCAGCTCGAACGGGAGGTCAACTTCCTCAAGGAAGCATATGAAGTGAATGCAACGGGGACCGAACCCAGCAAAGAGAATGAAACCTCATCCGGAGCGATTGTAGCATTGGAAGTGACGGATCCGGTTAACGCTGTGAATGATACACCGTCCGAGCGGATCGATAGTTCCGAACGGTTGGCTGCCATGTTGCTAAACGATGGTCTGCAGCCGGATGATACGCAAAGCAGCAACGGTGAGGGCAGTTGCCATGGTAACATTTTCCAGCATGAGGAGGATCACTTTGCTTCTACTAAAGCGTATGCAGAATCAATGCATATGCTAGAATTAGCAGATGTGGCGAAGCAAGAGATCAAGCTGGACGAAGAAAACGATCCGGATGAAAGCTGTCTGTACATGGACAAAACCAACATTACCTCAGAAGACACCGGTGCTGCATCCAATTATCGATGTTCGATCTGTGCGGCCTGCTTTGATGATCGAGCACAGCTCATCCTACACGTTCCGGTACATATTTAA
Protein Sequence: MNHNAFPVWQVAASEQQTTRGSTTGTQNNGGSISTLKYVTNARPNVKIISIPGRVGAGSNNTDGTLLYETSFDGSYLTVTKDHHHQQQQQPLRRSTPNHGVAMLNDSILLQTPDGQGYHLVDERSIQNIDQIPPENLIYMTSSEVSPLVSDVDKINPLTVPCLSTSSEQNQLELGDYVDSGPASEAVDETPQLQTDYAEECQVTEEVITDDWVQSQGEECVQVTVDQLGVNTIAVEDEIPVPLDQDQYTLSRPYPCDFCSRRFRKKASLQNHLMAHSNDRPHMCNLCGAQYGRRSDLINHLKQHAYAGTEQDDLSLRGDQDADYDLPELTNTAAHLKHRTRHSSEDEDLYIQNAMVSYNSQPPMQLISTTNYGSSSATISSSYDHNEAMERTSFSNGPTEIDHQSSIIDIGYPSPTLPAISAGKRMPRKRQIPSSDLRTARTKPAPSTKTTTQVRSSGASRTSVTSNRQIKKEPIDNSEGDTVPAPATVFPVIDERKPFVCQQCGISFGREKALMAHSRTHANRAHYECDHCFATFSDWSQLQEHVRRTHQLHSTKSEPPASTESKSEWVPDHETTYDHDSGGTSVDTKNRYNCDKCSAVFFQLEHILNHKQLKHGVTGSAVDASPQRKLVIKQERTTHHNVGYDDLEQDVTDQEIEEDDYGNLDYSIEHYESRSSDPETNAQQPTIALTCRECGDTFENGMELLEHSETHNRYEPHECQLCGEKFLEEATIKQHVQERHGNELTTTSCAICGKRCKSQTTLIKHAWDHSRERTHSCSQCGKTFHHMTRLKRHMESHRNKTVRCEVCNQEFPDGRTLMNHRHSHTKSNEYPCHECGKTFGSRSSQQIHMRIHTGERPYACRYCWKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHSQADAKRGSPNQPYYCSVCSAPFSTTDDLVQHLIKHSDMNTAMKREPPTFPRKYKRRRKLKPHELERLQSGRRKQKNKPSEELEDDGDDAGFEESASATESTKQQQYEPKPSLVLSHPDGTLKTKRELKLEYGRRGESHGSKPSLSPNGMLDENGINLLSNIVLLHGEQDDPSNADNDKLSRGAKKPVETTPKEKAGPSNCRPSANAPKWNATPTRKKPSRKRTASFASGDSSEALVKVKEEEHSSPQSAGSTITNVMEAFFRTRKRNSLLPEISSHRISSVSFPLLDDGNTDDPMDEPMVDDGCRRGYGQHTPQQTRKSTASFSASEDDLNHQLLMEISHKNKYTDRFNSDTVHDLQEILRSPIKGAPSRNELSTPSTKRANPNKQDGKPSAQRKQKGKSKAKNKKTVPVRPQQKPVEKKIKKVAPETPPAVLRSQRLTRRQLEREVNFLKEAYEVNATGTEPSKENETSSGAIVALEVTDPVNAVNDTPSERIDSSERLAAMLLNDGLQPDDTQSSNGEGSCHGNIFQHEEDHFASTKAYAESMHMLELADVAKQEIKLDEENDPDESCLYMDKTNITSEDTGAASNYRCSICAACFDDRAQLILHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105291;
90% Identity: -
80% Identity: -