Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI422658:10904-14947[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00099 0.058 13.6 6.4 1 23 230 252 230 252 0.98

2 11 1.8e-06 0.0001 22.2 0.2 1 23 282 304 282 304 0.98

3 11 4.1e-07 2.4e-05 24.2 0.8 1 23 310 332 310 332 0.98

4 11 9.1e-07 5.3e-05 23.1 3.5 1 23 338 360 338 360 0.98

5 11 0.00024 0.014 15.5 1.1 1 19 366 384 366 387 0.95

6 11 1.4e-05 0.00081 19.4 0.8 1 23 393 415 393 415 0.98

7 11 1.6e-07 9.1e-06 25.5 1.1 1 23 424 446 424 446 0.99

8 11 8.6e-07 5e-05 23.2 0.7 1 23 452 474 452 474 0.99

9 11 0.0084 0.49 10.7 0.3 1 19 481 499 481 500 0.96

10 11 0.00021 0.012 15.7 1.1 1 23 602 624 602 624 0.98

11 11 2.5 1.5e+02 2.9 0.1 1 10 678 687 678 691 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00099	0.058	13.6	6.4	1	23	230	252	230	252	0.98
2	11	1.8e-06	0.0001	22.2	0.2	1	23	282	304	282	304	0.98
3	11	4.1e-07	2.4e-05	24.2	0.8	1	23	310	332	310	332	0.98
4	11	9.1e-07	5.3e-05	23.1	3.5	1	23	338	360	338	360	0.98
5	11	0.00024	0.014	15.5	1.1	1	19	366	384	366	387	0.95
6	11	1.4e-05	0.00081	19.4	0.8	1	23	393	415	393	415	0.98
7	11	1.6e-07	9.1e-06	25.5	1.1	1	23	424	446	424	446	0.99
8	11	8.6e-07	5e-05	23.2	0.7	1	23	452	474	452	474	0.99
9	11	0.0084	0.49	10.7	0.3	1	19	481	499	481	500	0.96
10	11	0.00021	0.012	15.7	1.1	1	23	602	624	602	624	0.98
11	11	2.5	1.5e+02	2.9	0.1	1	10	678	687	678	691	0.87

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATCGATCAATAAAAATAAGATATTTACTCAACGGTACGGCAACAGTAATAACGATATTTGTCGGCTGTGTTTAAAAAATGAAGCGCACATGGAACCACTGTTCTACTCAAACCTTTTCCCCAACATTTTACTCACGAAAAAGATATACGATTGTACATCCATACAGATCATCTACGAGCGTAACTTGCCAATGTTTGTGTGTAAACTTTGCGCCAACAAGCTGGACGAGTATGTGCGTTTCCGCGACCGTTGCATAGCGAATGATGAATTTTTACGCAACGCTTTAGCGGCATTCGATGCCAACGGTGGAAGCTGTTCGAGTGCGATAAAAATGGAACCGGAAGACACACCGCCTCCTCCCCCGTTGCCACAATCTGCTCCGACGACGACAAAGTTTGCCCAATGCCTTGCGGTTACACCGATGGAACTAAACTGTGCCCTAGTGGCGGCAGCTGCTGCCGCGGCCGGTCACCAGAGCAGTAAACAAGAACCACCGGATGTGGAGGAACATCATGGCAGATATGGACACGGTTCTGGTGCGATATCGCCCGATCGGTCCGACGAGTTGGCCACACTGAAGCAAACGCACGATGATCACTACCGGAGTGGCGAAGAGGACGAACTACCTGCCGATGATGCCTACGGTGAACCGAACCAAACCGATGCCAAACATTATGTGTGTGAAGTGTGTTCGAAATCGTTCAAAATACGCCATCATTTGCTGGTGCACAGGCACACGCATGTGGACAATCATGCGTCACCGATCAACGGTTTGTTGCACGGGGGAACCGAATTTAACAGTCCCGTTTCCGGAAGCGGGAAACAGTCGTACAACTGTCCGAAGTGCGCCAAAGTGTTCGTCAACAAGGGCAATCTACTGAATCACCTCGAGACGCACACGAACGAGAAAAGCTACGCGTGTGATATCTGCACGAAAACGTTCAAGTACAACGTGCAGCTACGGTTGCATATGCGCATCCATACCGGCGAACGGCCGCACAAATGTGAGATCTGCAATCGTGGATTTTCGCAGCTGTCGAACTTGCGATCTCACCGCAAAACTCACTCCAAAGTCAAACCGTACAAATGCCATTTATGCCTCAAAAGCTTCACCATGCTGGACAACCTGACCGCGCACAGTTCAAAGTGTCTGAAGGATAAGTTTCGCTGCACGCTTTGTTCCAAATCGTTCGCCAAGGAGggcaacctgctgtcgcacttgcagtcccacagtgatggtatcgtggagaaaatgttcaagtgcgaaatgtgcccgaaaagcttcaaaaacaaggaggactggaagcggcacgtgcgtgtgcacacgggcgaaaaaccgtacacctgcgatatctgctcgaagggatttgcCCAGAAGGCGAATCTGTTGTCCCACCGGAAGACACACCTGAAGCCAAACGTTATTTACAAATGTGATCGATGTGCGAGAACCTTTCGTTCGCAGAAGGTGCTCCAAATGCACGCACCGAAGTGTGTCGGTGTTGGTGTTGTTGATGGGGCCAGTGTTCCTTCCGCCCCGGTAACACCAGTGTCCGAATCAATTCCGGGCTCTCCGAGTCCTGCTGGAACAGCTGTCACATTGGCTGGTGCGACGTCTGCTACCGCGGCCGTGGCCAACAACACACCAACACTGTCGGAGGCTCTGTCCGATCTGCTGCGGTACGAGATAGCACTGAGAGCACCCTTGGAATTGCAGCAAATGCTTCTCGGGCATATCGATCGTAAGAAGCCCACGAACGGAACGGGTGGAAAAGCGACTGGGCGACGATATAGATGTGATGTATGCTTCAAAGGCTACTCGCAGTATCCGTCGCTGATCAAGCATCGGAAGCTACACTTTAAGGTACCTCCACTGGTGAAGGTTTTGGCGGGAAAGGGACGACACGCGGACTATGAGGAGCACGAGGACCCGGACGGAGCGGATTGCGAGGACGTACTCGATGGACTGGAACGCCGGGAAACGACGCCGGAGCCGCACGATTCGATCGAGCGGCCGTACAGCTGTGATATATGCGGCGGAAGATTTGAAGCAGCATCTGCACACCCACCCGACCGATGCCGGCAGGAGCTTCAGCTGCGAGTACTGCTCGAACCGATTCCGCTCGAACGAGGACTTGAAGCGGCACCGGAGATCGCACACCGGCGAACGACCCTTCCGGTGCCCACGCTGCCCGAAAGCGTTTACCCAGCAGTCGAACTTGCGGGCCCACACGAGGATCCACGAGCGCTAGGGGACGTGCAACAGGTGGTGCCAGTCGCAACAGTCTCCTCCCCGGATGCCGGAAAAGGAGGGATGCTGCAACCCGTGCCAACGGGCGAACCGGCATGCGTAACATAA
Protein Sequence: MAEDLSINKNKIFTQRYGNSNNDICRLCLKNEAHMEPLFYSNLFPNILLTKKIYDCTSIQIIYERNLPMFVCKLCANKLDEYVRFRDRCIANDEFLRNALAAFDANGGSCSSAIKMEPEDTPPPPPLPQSAPTTTKFAQCLAVTPMELNCALVAAAAAAAGHQSSKQEPPDVEEHHGRYGHGSGAISPDRSDELATLKQTHDDHYRSGEEDELPADDAYGEPNQTDAKHYVCEVCSKSFKIRHHLLVHRHTHVDNHASPINGLLHGGTEFNSPVSGSGKQSYNCPKCAKVFVNKGNLLNHLETHTNEKSYACDICTKTFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTMLDNLTAHSSKCLKDKFRCTLCSKSFAKEGNLLSHLQSHSDGIVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHRKTHLKPNVIYKCDRCARTFRSQKVLQMHAPKCVGVGVVDGASVPSAPVTPVSESIPGSPSPAGTAVTLAGATSATAAVANNTPTLSEALSDLLRYEIALRAPLELQQMLLGHIDRKKPTNGTGGKATGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLAGKGRHADYEEHEDPDGADCEDVLDGLERRETTPEPHDSIERPYSCDICGGRFEAASAHPPDRCRQELQLRVLLEPIPLERGLEAAPEIAHRRTTLPVPTLPESVYPAVELAGPHEDPRALGDVQQVVPVATVSSPDAGKGGMLQPVPTGEPACVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -