Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI423596:7249-14499[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.4e-05 0.002 18.2 0.9 1 23 228 250 228 250 0.98

2 17 0.0021 0.12 12.5 0.2 1 23 502 526 502 526 0.95

3 17 0.0063 0.36 11.1 1.1 1 23 559 581 559 581 0.96

4 17 5.2e-06 0.0003 20.8 0.5 1 23 587 609 587 609 0.93

5 17 3.4e-05 0.002 18.2 4.0 1 23 615 637 615 637 0.99

6 17 0.01 0.6 10.4 2.9 1 23 643 665 643 665 0.98

7 17 1.3e-05 0.00074 19.5 0.7 1 23 671 693 671 693 0.97

8 17 2.9e-07 1.7e-05 24.7 1.5 1 23 699 721 699 721 0.99

9 17 0.047 2.7 8.3 0.2 1 23 980 1004 980 1004 0.95

10 17 0.56 32 4.9 8.6 1 20 1009 1028 1009 1031 0.94

11 17 0.00016 0.0091 16.1 1.8 1 23 1037 1059 1037 1059 0.97

12 17 3.1e-06 0.00018 21.5 2.6 1 23 1065 1087 1065 1087 0.95

13 17 0.0018 0.1 12.8 2.7 2 23 1094 1115 1093 1115 0.97

14 17 0.00022 0.013 15.6 2.4 1 23 1121 1143 1121 1143 0.98

15 17 3.3e-05 0.0019 18.2 5.6 1 23 1149 1171 1149 1171 0.99

16 17 1.5e-06 8.5e-05 22.5 2.9 1 23 1177 1199 1177 1199 0.99

17 17 0.00075 0.044 14.0 0.6 1 23 1205 1227 1205 1227 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.4e-05	0.002	18.2	0.9	1	23	228	250	228	250	0.98
2	17	0.0021	0.12	12.5	0.2	1	23	502	526	502	526	0.95
3	17	0.0063	0.36	11.1	1.1	1	23	559	581	559	581	0.96
4	17	5.2e-06	0.0003	20.8	0.5	1	23	587	609	587	609	0.93
5	17	3.4e-05	0.002	18.2	4.0	1	23	615	637	615	637	0.99
6	17	0.01	0.6	10.4	2.9	1	23	643	665	643	665	0.98
7	17	1.3e-05	0.00074	19.5	0.7	1	23	671	693	671	693	0.97
8	17	2.9e-07	1.7e-05	24.7	1.5	1	23	699	721	699	721	0.99
9	17	0.047	2.7	8.3	0.2	1	23	980	1004	980	1004	0.95
10	17	0.56	32	4.9	8.6	1	20	1009	1028	1009	1031	0.94
11	17	0.00016	0.0091	16.1	1.8	1	23	1037	1059	1037	1059	0.97
12	17	3.1e-06	0.00018	21.5	2.6	1	23	1065	1087	1065	1087	0.95
13	17	0.0018	0.1	12.8	2.7	2	23	1094	1115	1093	1115	0.97
14	17	0.00022	0.013	15.6	2.4	1	23	1121	1143	1121	1143	0.98
15	17	3.3e-05	0.0019	18.2	5.6	1	23	1149	1171	1149	1171	0.99
16	17	1.5e-06	8.5e-05	22.5	2.9	1	23	1177	1199	1177	1199	0.99
17	17	0.00075	0.044	14.0	0.6	1	23	1205	1227	1205	1227	0.98

Sequence Information

Coding Sequence: ATGTTGGAAAAGCTATTTCCAGCTATATTTAACTCGGAACAGCTGAATCACGACCGTAGCATGAATTGGCCTGGAACAATTTGCCGCGACTGCAAATGCAAAGTGATTGATGCGTACGCATTGTACGAGCAGTGTGAGAAAAGTGTTGATCTGTTAAACCAGCAGCAAATGACTTCGATGATCTGCAATGGAGCATCAATTGTTAGCAACGGGCAATATTTTAATGACAAACGTTCGGAGGATACGCCACTGCCTACGGAAGAAATATTTGCCCTACAACTGGTGAAGCTCGACGACAGTATGCAATTGCCATCTACCGCATCCCTAGATGATAAGTGTAACGAGATAAATACGCACGTGTTGCAAGATCAATGTGAGATGAGTGACGATTTGTTAAACCATCAACAGTCCAAACCAATCAGTAACGATGTGCCAATTTTAATTAAGGGAAAATCAGTAGCAAACTATCCGTCAGAGGAAGAACAACTGTTAACTGACCTTCAACCTCTAGAAGTATCCTCATCCGTACTATTAGTTGATCTCGATGAAGATCCAATTCTTCCAAGCGAGCGTCCGTTTGGTTGCGAAATCTGTGGCATGCGGTATGGTATCCATTCGTTGTGGCGTCTGTTGAGTAACGATATGGTGAAGCATATGAAAATACACGTCGGTAACAACCCGTACCAGTGCGATCGTTGTGACGAATCGTTTCGGCTGCTTTCGGATCTCCGCAATCACTACAAAGCACATTATCAGACGGGCGAGCCTGATCCTGGTTCTTCGCCGGAACAAGGCGATGGTATACGTTTTACCAGCATTGATATTCTGCAGATAAGATATAAAAAAGAAAAGGGTACATTAGAAAAGTTGTTTCCAGCCGTGTTTAATGATGAGCAACTGCAGCATGACTACAGCATGAACTGGCCAAAGGCGGTTTGTCGGGATTGTAAGCAGAAGGTCCAAGATGCGTACGAACTGTACGAAACTTGCCTCGATAGCAGTGATAAGTTGCTGAAAAAGGGTTTTGCCAAAGATGAAAAGTTTGACCAAGAGATTACCATTCATCCGGAGGATTGCATTGCAGATGTATCAACGGAAGAGTTCATTGAGTGTGATCTTATTCAACAAAGCGTTGAAGAGCCCCAAGAACCACAACAATCCCTAATCGTTTCACTACAATCCGTGAAAACGCGCAAAACCGAAGCGAAAGAAACGGCGAGAGCGAAGAAAGTTTCAACCGTCGTCGAACCAGTGAACATCAAGGAAGAAATCGAAGAGCTAGTAACGGAAGAGCTGATCGACGCAAATGATGCTGAATTTCTTGAAGCAAAAAGCGACGAGCCTGATTGGGAACCACCACCAGCACACAAAAGCAGAAAAGCCGCATCTACAAGAGCaaaaactgagaaaacttcacggggacggatgaaaaaagagaaaaaagttaaaacaaaGCGTGAAGATAAGGTACAGGAAGAGATACTGGAATCAACCATCGAGGTATATCCGTGTCAAATATGTACTGGACTCACCTTTTCGTCACCAAAAGAACTGACCGACCATATGAAGGAGAAACATTCGAATCAGATACGATCCTGCGACAAATGTCCGAAGGTGTTTGTTTGCGAGCAAACCTTCCAGCACCATCAGTACTGTCACGCAACGGGACGTTCGTTCTTCTGTGCGTTCTGTAACAAAGGTTTCCAGACGGAAATGTTGTTAAAAAGTCATGTGCAATCGCACGCACGTCAACCGAAATTCCTATGTTCCATCTGTGGAAAGGGCTTCATAAACAAAAGCGGTCTTCAGAAACATATAACATTCCACACGGATAGCAAATCCTATCCTTGCAGTTTATGTCCATGCCGTTTCAATACAAAAGCTTGCTTAAATGTGCATATGCGCACCCACACGAAGAACAAGATTTACACTTGCTCAACCTGCGGTTCACAGTTCAATAAGCACTATTCGATGGTAAAGCATCAAATAATTCATACAGGAGAGCGTCCGTTTGCGTGTGATGTGTGTCCCATGAGATTCATCTCACCGTATCATGTAAAGCGTCACATGCTGACCCACACGGGTGAAAAGCCTTACAAATGTACGTACTGCGATCGTAGCTTCGCACAAAGCAACGTGTTGGTAAAGCATATGCGAACACATATCGTTACAATGGAGGAAGAGTTTTTGACCATCGCTTTAAAACCGACACTTTGTCGCATTTGTGCTGTTGTATGCACCGAGCAATACTGTATTTATGAAGCTGTTTACAAGGAAGAAACACTCAGCATGCACATGATGATGGAAAAGTTAGTTCCCTCGGTGTTTAACGCGGAACAAGTGAAGGTGGACGAGTTCATGTGCTGGCCAAGAAAGATTTGTGCAGAGTGCAAACACAAAATACTGGAAGCGTACGCTTTATATGAGCAGTGCATAAGGAGTGGCGATCTGTTGAGAGAATGTTTGTCACGAAAAACTGAATCATTCATCATAGAAGACGTGTACGAAGAAGTGGAGCAGACTTTAATCGATAGCTCAGAGCTAGTATCCAACTATGCGGATGATGAAACGTACGAACCAACACCAATAGTTCAACGGCCAATGCGTAAAAAAGCTGCTCGCAAATCGAATGTTCGGGACATTTCAACAAATAAGCTAACGTCAGACATAAAAGTAGAACGTGTATCCACACCATCCGAGCAGTACGAGCATCAATCAGATGATAATGATACCTCATTTATCAGCGCTAGCACATCAAACACAAAAGCTTCACACAGTACCTCCACGCGACAAAGAAACGCATCCTCCAAGCGCAGTTCTGCTGCAGGCAACGAGAAAACGCAACGAGGTAAACCAAGAACTTCACGAAAGATACAGAAGGATAATGAAGACCCCATCTTAGATGAAACGAAAGAACCGGAAACAAAGGTAGATACATACCGGTGTTTGCTTTGTAATGCACCGACGTACTCCTCGCCGAAGGAACTTACGGAACACTTGAAAACAGAGCATCCCGATCAGATTCACTGTTGCAAACAATGCCCGAAGGTGTTCATGACCAAAGTGGCCTTCGAGCATCATCAGTACTGCCATGCTACGGGACGATCGTTCTTCTGCATGTTTTGCGACAAAGGCTTTCAAACGGAACAGCTGCTTAAAAACCACATAAGGACTCACACGCATGGCACGGGCTTTCTGTGTTCACACTGTGGACAGGAGTTTAGCAACAGAAGCAATCTTCGCCAACATCTGATACGTCATACCGGTGATAAGCCATGGCAATGTACCTTATGTCCCAGCCGTTTCAGCATGAAAAGTTATTTGGATAGACACCAGCATACCCACACGAAAGCGAAATACTTCAGCTGTGACACATGTGGATCTCAATTTAGCAGACATTACTCATTAGTAAAACATCAACTCATTCATACTGGTGATCGCTACTTCACGTGTGAGGTTTGCAATATGAGGTTTACCTCAAGCCATCACGTAAAACGACACATGCTAACGCACACGGGAGAAAAACCATTCAAATGTACATACTGCGAGCGTAGCTTTACGCAAAGCAACGACATGGTGAAGCATATGAAAACGCACGTCGGTAACAATCCGTACCAGTGTGACCGTTGCGATGCAGCGTTCCGACTGCTTACCGATCTTCGGAATCACTACAAAGAGCATTACCAGGCGGGCAATAAGGATGCACTTTCCGGCGAAGAAGATAAAAACATACGCTTTACAAGCACGAACATTTTGAAAATTCGATACGAAAAGGAAATGAACCAATCAATCGAGAAATTTAGCACAGAGATACTAAAATAG
Protein Sequence: MLEKLFPAIFNSEQLNHDRSMNWPGTICRDCKCKVIDAYALYEQCEKSVDLLNQQQMTSMICNGASIVSNGQYFNDKRSEDTPLPTEEIFALQLVKLDDSMQLPSTASLDDKCNEINTHVLQDQCEMSDDLLNHQQSKPISNDVPILIKGKSVANYPSEEEQLLTDLQPLEVSSSVLLVDLDEDPILPSERPFGCEICGMRYGIHSLWRLLSNDMVKHMKIHVGNNPYQCDRCDESFRLLSDLRNHYKAHYQTGEPDPGSSPEQGDGIRFTSIDILQIRYKKEKGTLEKLFPAVFNDEQLQHDYSMNWPKAVCRDCKQKVQDAYELYETCLDSSDKLLKKGFAKDEKFDQEITIHPEDCIADVSTEEFIECDLIQQSVEEPQEPQQSLIVSLQSVKTRKTEAKETARAKKVSTVVEPVNIKEEIEELVTEELIDANDAEFLEAKSDEPDWEPPPAHKSRKAASTRAKTEKTSRGRMKKEKKVKTKREDKVQEEILESTIEVYPCQICTGLTFSSPKELTDHMKEKHSNQIRSCDKCPKVFVCEQTFQHHQYCHATGRSFFCAFCNKGFQTEMLLKSHVQSHARQPKFLCSICGKGFINKSGLQKHITFHTDSKSYPCSLCPCRFNTKACLNVHMRTHTKNKIYTCSTCGSQFNKHYSMVKHQIIHTGERPFACDVCPMRFISPYHVKRHMLTHTGEKPYKCTYCDRSFAQSNVLVKHMRTHIVTMEEEFLTIALKPTLCRICAVVCTEQYCIYEAVYKEETLSMHMMMEKLVPSVFNAEQVKVDEFMCWPRKICAECKHKILEAYALYEQCIRSGDLLRECLSRKTESFIIEDVYEEVEQTLIDSSELVSNYADDETYEPTPIVQRPMRKKAARKSNVRDISTNKLTSDIKVERVSTPSEQYEHQSDDNDTSFISASTSNTKASHSTSTRQRNASSKRSSAAGNEKTQRGKPRTSRKIQKDNEDPILDETKEPETKVDTYRCLLCNAPTYSSPKELTEHLKTEHPDQIHCCKQCPKVFMTKVAFEHHQYCHATGRSFFCMFCDKGFQTEQLLKNHIRTHTHGTGFLCSHCGQEFSNRSNLRQHLIRHTGDKPWQCTLCPSRFSMKSYLDRHQHTHTKAKYFSCDTCGSQFSRHYSLVKHQLIHTGDRYFTCEVCNMRFTSSHHVKRHMLTHTGEKPFKCTYCERSFTQSNDMVKHMKTHVGNNPYQCDRCDAAFRLLTDLRNHYKEHYQAGNKDALSGEEDKNIRFTSTNILKIRYEKEMNQSIEKFSTEILK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -