Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI423596:1583-6791[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.46 26 5.2 0.2 1 23 289 313 289 313 0.94

2 18 0.098 5.7 7.3 2.8 2 20 319 337 319 340 0.94

3 18 0.0017 0.1 12.8 2.3 1 23 346 368 346 368 0.97

4 18 2.7e-06 0.00016 21.6 1.8 1 23 374 396 374 396 0.94

5 18 0.00017 0.0097 16.0 1.5 3 23 404 424 402 424 0.97

6 18 0.00069 0.04 14.1 2.6 1 23 430 452 430 452 0.98

7 18 0.00038 0.022 14.9 1.2 3 23 460 480 458 480 0.98

8 18 1.6e-06 9.1e-05 22.4 1.4 1 23 486 508 486 508 0.99

9 18 0.0073 0.42 10.9 0.4 1 21 514 534 514 535 0.96

10 18 0.095 5.5 7.3 0.3 1 23 808 832 808 832 0.95

11 18 0.037 2.2 8.6 4.3 2 20 838 856 838 859 0.94

12 18 0.00084 0.049 13.8 1.0 1 23 865 887 865 887 0.96

13 18 4.4e-05 0.0026 17.8 0.1 1 23 893 915 893 915 0.93

14 18 0.0012 0.072 13.3 4.1 1 23 921 943 921 943 0.98

15 18 0.0088 0.51 10.6 2.9 1 23 949 971 949 971 0.98

16 18 1.9e-05 0.0011 19.0 0.8 1 23 977 999 977 999 0.97

17 18 2.5e-07 1.4e-05 24.9 1.5 1 23 1005 1027 1005 1027 0.99

18 18 0.00032 0.018 15.1 1.2 1 23 1033 1055 1033 1055 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.46	26	5.2	0.2	1	23	289	313	289	313	0.94
2	18	0.098	5.7	7.3	2.8	2	20	319	337	319	340	0.94
3	18	0.0017	0.1	12.8	2.3	1	23	346	368	346	368	0.97
4	18	2.7e-06	0.00016	21.6	1.8	1	23	374	396	374	396	0.94
5	18	0.00017	0.0097	16.0	1.5	3	23	404	424	402	424	0.97
6	18	0.00069	0.04	14.1	2.6	1	23	430	452	430	452	0.98
7	18	0.00038	0.022	14.9	1.2	3	23	460	480	458	480	0.98
8	18	1.6e-06	9.1e-05	22.4	1.4	1	23	486	508	486	508	0.99
9	18	0.0073	0.42	10.9	0.4	1	21	514	534	514	535	0.96
10	18	0.095	5.5	7.3	0.3	1	23	808	832	808	832	0.95
11	18	0.037	2.2	8.6	4.3	2	20	838	856	838	859	0.94
12	18	0.00084	0.049	13.8	1.0	1	23	865	887	865	887	0.96
13	18	4.4e-05	0.0026	17.8	0.1	1	23	893	915	893	915	0.93
14	18	0.0012	0.072	13.3	4.1	1	23	921	943	921	943	0.98
15	18	0.0088	0.51	10.6	2.9	1	23	949	971	949	971	0.98
16	18	1.9e-05	0.0011	19.0	0.8	1	23	977	999	977	999	0.97
17	18	2.5e-07	1.4e-05	24.9	1.5	1	23	1005	1027	1005	1027	0.99
18	18	0.00032	0.018	15.1	1.2	1	23	1033	1055	1033	1055	0.98

Sequence Information

Coding Sequence: ATGGATGTGAAAACGGAGCTGATTTCATCAGCTGTGATAGAATTGGAGGTTTGCCGTATCTGTGTCACGGAATCAGTAGAGCAATGTTCCATTGACGATGTGGTAGATACAGAAAGATGTTTGAGCCTAGGCATAATGCTGAAGACCATGTTTCCCTCAACGTTTAACCCGGAAGCAAAGTCGGTGGATGGTATGAGCTGGCCATCGAAAGTTTGCCTTGCCTGTAAGGAAAAGGTGCTGGTCGCATACGAGCTGTACACGCTGCTGGTTATGAACGAAGATTTTCTGCAGCGCTGCTTAGAAGAGCGAACCCGTATCGAAGTTGAAACCGTAAAATCGGAACAAGACGGCAGCTCGAGTGCACCATACGATGTGTTAATTGAGTATACGTTCGAAGATGGAAACACCTACACAACCGAGGTGGAGCATCTGATCGATGAAACAGGCGATGATGATGCACTTTCCGAAACGCAAACCACTGGGGAACCCTCGACGAATGATGAAAGTGTTACCCGTGTGTCAACGAGGAGACGCACCAGACCGCAGCGGGATGTGCCCGCGAAGAAACGATCGCGGAATCAGCTGAAGCAAGATTTAGCCCAGGAAGAAACTAGCACGGACCGGGAGCAAAGTTCTGCAGCGAATGCAAACGATACACTAACGCAATCAAACGATGAAGAAGACAGCATCGACCTCGAAAGGAAACCGAAGGGTAGAAAAAGAGGCCGGAAACCTAAAAACAGGGCTGAAAATTCCGCTAGCAAAGATAAAGAGGATGGGCGAGAAAAGAAGAAACGAACGAAAATCAAACCAGAAGACGACTCGTCGGACCAAGTCGAGGAATTACAGTCCAAGGTGGATGTGTACCAGTGTCAGCTGTGCGAAGGGCATACATATGGTTCACCGATGGAACTGACCGTCCACCTGAAGGCGGAACATCCGGATCAGATTCGAACCTGTGACAAGTGTCCGAAGGTGTTTATGAGCGAGCCAGCCTATCAGCATCACCAGTATTGCCACGCCACGTTGCGCTCTTTCTTCTGCATGTTCTGCGACAAGGGCTTCCAGACGGAAAATTTGCTCAAAAGCCATACCCGGTCGCACACGCACGTAGCCGAGTTTTTGTGTTCATTGTGTGGTAAAAAGTTCAATAGTAAGAGCAATCTGCGGCAGCATTTGGTGCGTCACACGGGTGTAAAAGCTTGGGCCTGTACCCAATGTCCGAGTCGGTTCTGTACGAAAGGTGCACTAAACTTACATCAGCGAACACATTCGAAGCTGAGACCTTTTAGTTGCGATACGTGCGGTTCTCAATTTCACACGAGATACTCTCTGATCAAGCATCAATTAATTCACACAGGTGAGCGTCCGTATGGTTGCGATCTGTGTCCAATGAGATTTGTCTCAACGTATCATGTTAAGCGTCACATGTTGACCCACACTGGGGAAAAACCTTTCAAATGCACCTATTGTGACCGTGGCTTTGCACAGAGCAACGATATGGTGAAGCACATGAAAACGCACCTGGGTGAAAATCCGTACCAGTGTGACCGATGTGAAGCATCCTTCCGGCTGCTGACGGAACTACGCAATCACTACAAGGAAACGTGCCAGCCAGTCGACAAAGGGACTGTTTCCTGTCCGGAAGTGGAAAAAGGCATACGGTTTACCAGCACAAACATTTTAAAGATGAGGTACGAAAAGGAAATGGCCCAGTACAGTGAAAGCTTGCAAATCGCTTTGGAGAAGCTGTTCCCTGCAATGTTCAACGAGGCACAACTGCAACATGACTACAGCATGAACTGGCCAAAGGCGGTTTGTCGGGATTGTAAGCAGAGAGTCAAACAAGCGTATGTGCTGTACGAGACCTGCCTTGACAGCAGTGATAAGCTGCAGAAGCAGGGATATGCTAAAGGAAATCTTCAGGAGGAGGAGACAATCCTTCAGCGGGTAGATTTCATTGTCGATGAACCGTCGGAAGAGTTTGTTGGATATGAATATATCCCAGAAATCGTAGAGgaatcacaagaaccacaagagccacaagaaccacaagaaccaaaagaaccacaagaatcacaagaaccGCTTGTAGTTTCACGACAATCCAATAAAACGCGGAAAACCGAGGTGAAGGAATCAACAAGGACCAAGAAAGCTTCGACCGTTGTTGAGCAAGCCAACATGATGCAAGAATTAGATGAGATGGAAAAGCTAATAGACGAAAATGATGTAGAAATTCCCGATGAAAACAATACCGAACCTGATTGGGAACCACCAGCGCGCAGGGGCAAAAAACCCAGAGTTGCTAAACAGAAAACTGATAAAACTCCACGGGAACGGAAAAAGAGGGAGAAAAAACCCTCACCAAAGCAGGAAGATAATGAACAGGAAGAATCACTGGAATCCAGGGTAGAAATATATCGCTGCAAGCTGTGCAATGGTCCTACGTATGCGTCACCACACGACCTGACCGACCATCTGAAGGCGGAACATGCGACTCAGATACGATCCTGCGACAAGTGTCCCAAGGTGTTCGTTAGCGAGCAAACCTTCCAGCATCATCAGTACTGCCACGCAACGGGACGTTCATTCTTCTGTGCGTTCTGTGACAAAGGTTTCCAAACGGAAGTTCTTTTGAAGAGTCACATCCGTTTTCATACGCGAGGCACCAAGTTCCTGTGTGCAATATGTGGTAAACGTTTCGCAAACAATGGCAGTCTACAGATGCATGTACTGCTGCATGACGATAGCAAATCCTATGCTTGCAGTTTATGTCCATGCCGTTTCAATGCAAAAACATGTTTAAATGTGCATATGCGCACCCACACGAAAACCAAGATTTACACTTGCTCAACCTGCGGATCACAGTTCAATAAGCACTATTCGATGGTAAAGCATCAAATAATTCACACAGGAGAGCGTCCGTTTGCGTGTGATTTGTGTCCCATGAGATTCATCTCACCGTATCATGTAAAGCGTCACATGCTGACCCACACCGGTGAAAAGCCTTACAAATGTACGTACTGCGATCGTAGCTTCGCACAAAGCAACGTTTTGGTAAAGCATATGCGAACACATATCGGTGACAATCCGTATCAGTGTGATCGCTGTGACGCCTCCTTCCGACTGCTGAAGGATCTACGCAATCACTACAAAGAACACTACGACGAAAGCCAGAAAGGAATCGGCCCTTCGCCGGTGGTAGATGATAAGGATATTCGGTTTACTAGTACCGATATATTGAAGCTACGATATCGGAAAGAGATGAGTCAACTCAGTTTCAAGAATGAGGTAAACGAAGATACGAGCGGCTCTACGGTTTAG
Protein Sequence: MDVKTELISSAVIELEVCRICVTESVEQCSIDDVVDTERCLSLGIMLKTMFPSTFNPEAKSVDGMSWPSKVCLACKEKVLVAYELYTLLVMNEDFLQRCLEERTRIEVETVKSEQDGSSSAPYDVLIEYTFEDGNTYTTEVEHLIDETGDDDALSETQTTGEPSTNDESVTRVSTRRRTRPQRDVPAKKRSRNQLKQDLAQEETSTDREQSSAANANDTLTQSNDEEDSIDLERKPKGRKRGRKPKNRAENSASKDKEDGREKKKRTKIKPEDDSSDQVEELQSKVDVYQCQLCEGHTYGSPMELTVHLKAEHPDQIRTCDKCPKVFMSEPAYQHHQYCHATLRSFFCMFCDKGFQTENLLKSHTRSHTHVAEFLCSLCGKKFNSKSNLRQHLVRHTGVKAWACTQCPSRFCTKGALNLHQRTHSKLRPFSCDTCGSQFHTRYSLIKHQLIHTGERPYGCDLCPMRFVSTYHVKRHMLTHTGEKPFKCTYCDRGFAQSNDMVKHMKTHLGENPYQCDRCEASFRLLTELRNHYKETCQPVDKGTVSCPEVEKGIRFTSTNILKMRYEKEMAQYSESLQIALEKLFPAMFNEAQLQHDYSMNWPKAVCRDCKQRVKQAYVLYETCLDSSDKLQKQGYAKGNLQEEETILQRVDFIVDEPSEEFVGYEYIPEIVEESQEPQEPQEPQEPKEPQESQEPLVVSRQSNKTRKTEVKESTRTKKASTVVEQANMMQELDEMEKLIDENDVEIPDENNTEPDWEPPARRGKKPRVAKQKTDKTPRERKKREKKPSPKQEDNEQEESLESRVEIYRCKLCNGPTYASPHDLTDHLKAEHATQIRSCDKCPKVFVSEQTFQHHQYCHATGRSFFCAFCDKGFQTEVLLKSHIRFHTRGTKFLCAICGKRFANNGSLQMHVLLHDDSKSYACSLCPCRFNAKTCLNVHMRTHTKTKIYTCSTCGSQFNKHYSMVKHQIIHTGERPFACDLCPMRFISPYHVKRHMLTHTGEKPYKCTYCDRSFAQSNVLVKHMRTHIGDNPYQCDRCDASFRLLKDLRNHYKEHYDESQKGIGPSPVVDDKDIRFTSTDILKLRYRKEMSQLSFKNEVNEDTSGSTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -