Acru003355.1
Basic Information
- Insect
- Anopheles cruzii
- Gene Symbol
- -
- Assembly
- GCA_943734635.1
- Location
- OX030879.1:20237984-20239675[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0061 0.37 11.2 2.0 2 23 190 212 189 212 0.90 2 10 0.063 3.8 8.0 0.3 6 23 221 238 221 238 0.96 3 10 0.00021 0.013 15.7 7.2 1 23 244 267 244 267 0.96 4 10 0.015 0.94 9.9 2.4 3 23 277 297 275 297 0.96 5 10 2.9e-05 0.0018 18.4 0.5 1 23 317 340 317 340 0.96 6 10 5.2e-05 0.0032 17.7 1.5 2 23 349 370 348 370 0.97 7 10 0.0048 0.29 11.5 0.1 2 23 378 399 377 399 0.97 8 10 0.053 3.2 8.2 1.4 1 23 406 429 406 429 0.96 9 10 1.5e-05 0.00093 19.3 0.7 1 23 435 457 435 457 0.98 10 10 0.14 8.3 6.9 7.9 1 23 463 486 463 486 0.95
Sequence Information
- Coding Sequence
- ATGTTAACCGTTCGGGATCTCCGTAATGCTCCGTGCTCCTTTTGCTGCGCACACCACTGCAGCGGGCAATTATATCGGCTCTCCACGGTGGAGTTGTGGAAAAAAGCTGTACGAAAACACTTCTGGTTCGAGGACGAAATGCTCAACGACTTGTGGATGTGTTCGATCTGCTGGCAGCGAGTTCACGATTTCAGCTCGTTCTACGACGAAGTGAAGGAACGGCTGAAAACGCATACAAAGAGCACCGCAACGGGCACACTTTCCAGAACAATTGACATCGAAGTATTGCTCAAGGAAGAGTGTATTAGCGACGCAGAAACCGTACCCTCTATTCATGCCCATGACGAAGATGCTTTGCACGATCCACTCAACACTGCGCAACCCGATCGAGGCGCTGTCGAGGACCTATCATCCGCCACTAGAATTCGCTCGACTTTCGACGCAAGTAAAGCTGATAAAAGGCACAAAACATCTCCGCATAATTGCTCCGCATCGACAGAGATGAGTGCTACGGTAAACGATAGCCTCAAAATCACAGCCGCCGATATTGGGAACCACTACTCCTTACGGTGCAGCGATTGTAATGCCAACTTTGCCACGTTTGGCGATTTACAGAAGCACTGCAAATCGCTACACGACACCGTCGCTTTCGTGGAGTGCTGCGATCGAAAGTTTAAACGATACACCAACATCCGGGAGCACATTGTTTACCACCGCGATCCGAACGCCTTCCGGTGCAAGGAGTGTCCACGTACGTTTTCCACCAGCCGGTACCTGCACCAGCACCACTCCCGAACGCATCTTGCGTTCGAACAAAAACGCCATCTGTGCGACAAATGTAGCGATCGCTTCGCCACCCGTTACATGCTGATGATGCACGAACGAACGCATTACCGTGAGTCCGCGGAAACCGCAGAAGCGGCTGCACCGGCACCGAAACACGAACCGCATCCATGTGAACAATGTGCAAAAGCGTTTTCCACGTCGGCCAAGCTGGAGAAGCACGTGAACCGCGTGCACCGGCGGTCGGACTCCAGTTCGAAGATGTGCGACATTTGCTCGAAGATCCTGTACAACAAGTACAGCCTGGAGAAGCACCGAAGGACACACTTTAACGAGCATCCGACGGTCCAGTGTACGGTGTGTGGCAAGTGGTTGAAGAACGAAGAAACTCTGCGCATCCACCTATCGATGCACCGCCAGGAAAATATGGAGTTTATCTGCACGTTCTGCAACCACCGGTCACCCAGCCGGATCGCACTCCGCAGCCACGTGCTGCGCAATCACGAGAAGAAACGCACCCACCAGTGCTCGTTCTGTGAGAAGGCATTCGTGCAGGCCAATTTGCTGAAGGATCACATAGCGACGCACACGGGCGAGTATCTGTACCACTGTAAGTTCTGTGATAAACAATTTAAATGTAACTCAAACATGTCCAAACACGTGACCCGGCTCCATCCGTTCGAGTGGGCTGAGTACAAAAAGCGCAAAAATATGCCACCGGAGGTCATTTGCGAGACGGAGCAGCGCAAAAAAACGGTGAACAGATCCTGA
- Protein Sequence
- MLTVRDLRNAPCSFCCAHHCSGQLYRLSTVELWKKAVRKHFWFEDEMLNDLWMCSICWQRVHDFSSFYDEVKERLKTHTKSTATGTLSRTIDIEVLLKEECISDAETVPSIHAHDEDALHDPLNTAQPDRGAVEDLSSATRIRSTFDASKADKRHKTSPHNCSASTEMSATVNDSLKITAADIGNHYSLRCSDCNANFATFGDLQKHCKSLHDTVAFVECCDRKFKRYTNIREHIVYHRDPNAFRCKECPRTFSTSRYLHQHHSRTHLAFEQKRHLCDKCSDRFATRYMLMMHERTHYRESAETAEAAAPAPKHEPHPCEQCAKAFSTSAKLEKHVNRVHRRSDSSSKMCDICSKILYNKYSLEKHRRTHFNEHPTVQCTVCGKWLKNEETLRIHLSMHRQENMEFICTFCNHRSPSRIALRSHVLRNHEKKRTHQCSFCEKAFVQANLLKDHIATHTGEYLYHCKFCDKQFKCNSNMSKHVTRLHPFEWAEYKKRKNMPPEVICETEQRKKTVNRS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00094749;
- 90% Identity
- -
- 80% Identity
- -