Basic Information

Insect: Anopheles cruzii
Gene Symbol: -
Assembly: GCA_943734635.1
Location: OX030880.1:34240669-34243774[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2e-05 0.0012 18.9 3.3 1 23 131 153 131 153 0.98

2 16 7.7e-05 0.0047 17.1 0.9 2 23 196 217 195 217 0.97

3 16 0.0081 0.49 10.8 2.9 1 23 228 251 228 251 0.95

4 16 3.5e-06 0.00021 21.4 1.5 1 23 265 287 265 287 0.97

5 16 0.065 4 7.9 0.4 1 23 293 316 293 316 0.95

6 16 4.3 2.6e+02 2.2 0.0 2 23 427 449 426 449 0.89

7 16 0.00052 0.031 14.5 1.4 2 23 478 500 477 500 0.96

8 16 2.2 1.4e+02 3.1 4.3 1 23 511 534 511 534 0.96

9 16 7.4e-05 0.0045 17.2 1.8 1 23 661 683 661 683 0.95

10 16 0.032 1.9 8.9 0.5 1 23 689 712 689 712 0.86

11 16 0.0044 0.27 11.6 0.5 1 23 723 746 723 746 0.95

12 16 7.6 4.6e+02 1.4 2.4 3 23 777 798 775 798 0.94

13 16 2.8 1.7e+02 2.8 0.7 2 23 819 840 818 840 0.94

14 16 5.5e-06 0.00033 20.7 4.8 1 23 864 886 864 886 0.98

15 16 0.0038 0.23 11.8 0.5 1 23 892 915 892 915 0.96

16 16 0.019 1.2 9.6 1.8 1 23 928 951 928 951 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2e-05	0.0012	18.9	3.3	1	23	131	153	131	153	0.98
2	16	7.7e-05	0.0047	17.1	0.9	2	23	196	217	195	217	0.97
3	16	0.0081	0.49	10.8	2.9	1	23	228	251	228	251	0.95
4	16	3.5e-06	0.00021	21.4	1.5	1	23	265	287	265	287	0.97
5	16	0.065	4	7.9	0.4	1	23	293	316	293	316	0.95
6	16	4.3	2.6e+02	2.2	0.0	2	23	427	449	426	449	0.89
7	16	0.00052	0.031	14.5	1.4	2	23	478	500	477	500	0.96
8	16	2.2	1.4e+02	3.1	4.3	1	23	511	534	511	534	0.96
9	16	7.4e-05	0.0045	17.2	1.8	1	23	661	683	661	683	0.95
10	16	0.032	1.9	8.9	0.5	1	23	689	712	689	712	0.86
11	16	0.0044	0.27	11.6	0.5	1	23	723	746	723	746	0.95
12	16	7.6	4.6e+02	1.4	2.4	3	23	777	798	775	798	0.94
13	16	2.8	1.7e+02	2.8	0.7	2	23	819	840	818	840	0.94
14	16	5.5e-06	0.00033	20.7	4.8	1	23	864	886	864	886	0.98
15	16	0.0038	0.23	11.8	0.5	1	23	892	915	892	915	0.96
16	16	0.019	1.2	9.6	1.8	1	23	928	951	928	951	0.83

Sequence Information

Coding Sequence: ATGGATGCCGATGATGAACCGATCGTCAGTGGTGATCCGACAGAGGTTCCGAACCAGAACCCTGAAGTGTATTGTCGTTTCTGCTTTTCGGAAATAGACGTTCAGTCACTGTTTTCGGAGGAAAACAATACAAAGACTGATCTGCTGGCCCGTTTATCCGAGTGCATAGGATTAACCTTGACCCGAAATGACGACTATCCGAGCAGTATCTGCTCCATGTGTTCGCTTATGTTGGGGGACTTTCAGTGTTTTCGAAATCGCTGCCTTAAATACGACGCAGTCGTTCGTCGATGCAGGCAAGATTCGAAGCCCGTGGTAGAGCTGCTATCCCCCAAGCTGGAGAATGGTAGCAATCATGTGGAAACCTGTGCGCCATTAGACGATCTCGTGTTCGAGTGCCAATACTGTCCGCGGCAGTTTAAGCGGAAAAAGTACCTTAATCAGCACCTCACATCACATCGGCGTTTGCAGCAAATCACCGACGTAAACGGCCGTTCCACGACGAATGGAGTTCCTTCAGAAGAGGCCCCCGATCGACGGACGTTCAATGGAGTAAAGTATTCCGCATCCGGAGAACGCAACATAAGCTGTGCATACTGTCCGCGCAAGTTTACGCGCAACATGTACTACATTCAGCATTTGAAGACGCATGAACCGGACAGCGAGCGGAAGGAAAAACCATTCCAATGCCTCCACTGTCCGCGTTCCTTCAGTACGCGAGTACGACGAACGGTACACGAAAAACGGGAGCATCCAAAGAGGACCATCAAGAACAAGAATGAACCGAGTGCGTTCGTTTGTCCCGAATGTTCGAAATCTTTCAAGTATCGCTACTCCCTTCGTATGCACCTACTTAACCATCGTGGCCAGCTTCCGTTCGTGTGCGACGTTTGTAGTAGCGGTTTCTACAATGTCAACTATCTGACTGCGCACAAAGCACGCTATCATGGACCGAACGCCGTCGAGGTAGCGCTCAACGAAAGGGTGTCTTGTCGATATTGTCCACGGACTTTTCTGCGGAAGTGTGATCGCACATGCCACATGAAACAAATGCATCCAAACTACCCTCCCGAGTACGACGGTACTAATGATGAGAATGACGTACCAGGATTACTAGAAGACTGCCCACCGGCTGACAGCGAGGGATTGACCGATCCGGAACTACTGCCGCCGAACGTACACGAACCGATGATGGTGATAAAGGAGGAGGAACCATGCTCGGAAATGGCTTCGGAGCGAAGTGGTCAAAGTGGCTCAGTTAAACCAAATCCCACACTTTACTGTGAGTCGTGTGCAATGGGATTTGATACGGAGGATATGTACGCGGAGCACATTGATGATCAACACACGTTTCCTGAGCAGGGTTCAGTGAATCCTCCTGCCTCCGAAATACAGCACCCAATGATGCACCACAACCGGGCGAAAAAACTATACTGCCAGTATTGTTCGTCCTGTTTCAGTCGAGTCGGCTATTTGAACGCACATATGTTGCGGGTGCATCCGCGAGAGTACCAAAGCGTGATGGGTGCACACAAGTGCCGATTTTGTCCACGACAATTCGACAAGGTGCGGTATCGGAAGGTACATGAACGCATGACCCACCTGAAGCGCGGTGAGGTGCTACCGGAAGGAACCAAATCGGAAAGTGATATGGACACAGATGCCGGGACCGGCACAGCAAATTTTGAAGCAAACTTGTCGAGCGTATCGAATGACGCAATCAGCAATGATGCTTTGATTGATGAGCTTTGTCCTGCACGGCTTGTGGTAGTTTTGGACCGGCTGCCAGAGGAAGTGCTTGCATCCTACCAATGGCAATTGGATGAGTACTATCACACGACGCCTGAGGTGGCACCTGAGACGGAGCAATTGATCGAAATCGTGCCAAAGGAGGAAGAAAACAGTACTACGCCGAATCCGCCACACGAGACTGATGGTGACGTGGCCCTAACACAACGCACCAAACTTGGCATTAAGCTGCATCCTTGCGGCAACTGCCCCAAAGTATTTAAAACGCGGCAGGCCCTGCGGAAGCACTCAATGTACCACACCGGAGAGCTTCCGTTTCGGTGCGACGAGTGTGGGGTGCAGTTTATGCGTCCGGGACAGCTTTCCTTCCATAAGGCACGGTACCATGGTGACAGCGCACCGACGATAGTAAATCGCTATAGCTGTGATTATTGTCCCCGGATTTTTCTGCGTAAGCAAGATCTTGCCAGCCATTACTTCATGGTTCACAGGCGCGATCGGGCGGCGGAGGTATTCGCTAATGACGGCGTATCGCCCTCATTGGAACAGCGTAAAAAAAGTAAACGGAAGGAGTACTGGTGCCAGGTTTGTGCCAGCTCGTTCGAGCGGCACAGCAAATGCGAGCGCCACATTCTCCAAGCACATGGCCAGGACGGGAGCGTTGGTGCCGGCGGCGAGCAGGCAATGAAACCGGTTAAACTTTGTCGCTGTAACATTTGCACGGCGATTTGGAAGAAGCGTGAGGACTGGCTCGAACATCTGCGAGAGCATGCGAACATTAAACCACATCACTGCGAACAGTGCTTGAAGCGACGAAAAAAGTTTATCCGGAAGAAAATGCACAAGTGTACGTACTGTCCGAAAGTCTTCATTCACAGTACTACTCTGAAGTCACATCTTCGCATCCATACGCAGCAGCTACGCTTTCCGTGCAACGAGTGCGGTGTTATGTACGATCGGTACCGTTATTTGGCAATGCACAAACTTCGCTACCATTCGGAGGATGCATCCGCGGCGCCCCAGGCAGGATTGCATAAGTGTTCTTACTGTCCACGAATGTTTACACGCTTGCGCGATGTTAACTTTCATCAGGTTTCAGTACACGCAGATCAATCCACCCAGGCCATACAGGAGCTGGGAGAAGGACAGGACAGAGAACCCACGACAGATGAACAGGACCTGTTCTCCCACGAGTTTGGTAGTCTTTCGGAGATGCTTCTCAACAGCAATTGTAACGATTTGGCGCACAAGGCAAACATCAAGCAAGAATTTCCTTCCAGTTGA
Protein Sequence: MDADDEPIVSGDPTEVPNQNPEVYCRFCFSEIDVQSLFSEENNTKTDLLARLSECIGLTLTRNDDYPSSICSMCSLMLGDFQCFRNRCLKYDAVVRRCRQDSKPVVELLSPKLENGSNHVETCAPLDDLVFECQYCPRQFKRKKYLNQHLTSHRRLQQITDVNGRSTTNGVPSEEAPDRRTFNGVKYSASGERNISCAYCPRKFTRNMYYIQHLKTHEPDSERKEKPFQCLHCPRSFSTRVRRTVHEKREHPKRTIKNKNEPSAFVCPECSKSFKYRYSLRMHLLNHRGQLPFVCDVCSSGFYNVNYLTAHKARYHGPNAVEVALNERVSCRYCPRTFLRKCDRTCHMKQMHPNYPPEYDGTNDENDVPGLLEDCPPADSEGLTDPELLPPNVHEPMMVIKEEEPCSEMASERSGQSGSVKPNPTLYCESCAMGFDTEDMYAEHIDDQHTFPEQGSVNPPASEIQHPMMHHNRAKKLYCQYCSSCFSRVGYLNAHMLRVHPREYQSVMGAHKCRFCPRQFDKVRYRKVHERMTHLKRGEVLPEGTKSESDMDTDAGTGTANFEANLSSVSNDAISNDALIDELCPARLVVVLDRLPEEVLASYQWQLDEYYHTTPEVAPETEQLIEIVPKEEENSTTPNPPHETDGDVALTQRTKLGIKLHPCGNCPKVFKTRQALRKHSMYHTGELPFRCDECGVQFMRPGQLSFHKARYHGDSAPTIVNRYSCDYCPRIFLRKQDLASHYFMVHRRDRAAEVFANDGVSPSLEQRKKSKRKEYWCQVCASSFERHSKCERHILQAHGQDGSVGAGGEQAMKPVKLCRCNICTAIWKKREDWLEHLREHANIKPHHCEQCLKRRKKFIRKKMHKCTYCPKVFIHSTTLKSHLRIHTQQLRFPCNECGVMYDRYRYLAMHKLRYHSEDASAAPQAGLHKCSYCPRMFTRLRDVNFHQVSVHADQSTQAIQELGEGQDREPTTDEQDLFSHEFGSLSEMLLNSNCNDLAHKANIKQEFPSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094679;
90% Identity: iTF_00094679;
80% Identity: -