Acru010342.2
Basic Information
- Insect
- Anopheles cruzii
- Gene Symbol
- ZFY
- Assembly
- GCA_943734635.1
- Location
- OX030880.1:46562485-46566180[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 5.9 3.6e+02 1.8 0.2 1 10 137 146 137 152 0.84 2 14 0.00036 0.022 15.0 1.3 2 23 451 472 450 472 0.97 3 14 1.6e-06 9.8e-05 22.4 0.5 2 23 479 500 478 500 0.97 4 14 0.11 6.4 7.2 0.6 1 23 510 532 510 532 0.91 5 14 2.2 1.3e+02 3.1 0.0 3 23 557 584 555 584 0.78 6 14 6.5 3.9e+02 1.6 0.6 2 23 591 612 590 612 0.87 7 14 6.3 3.8e+02 1.7 3.4 1 23 618 638 618 638 0.76 8 14 0.0035 0.21 11.9 7.4 1 23 651 674 651 674 0.96 9 14 0.0017 0.1 12.9 0.3 2 23 680 701 679 701 0.89 10 14 2.6e-05 0.0016 18.6 1.5 1 23 706 728 706 728 0.92 11 14 0.0092 0.56 10.6 0.4 2 23 737 759 736 759 0.97 12 14 8.4e-05 0.0051 17.0 0.7 3 20 767 784 765 786 0.93 13 14 5.4e-05 0.0033 17.6 0.4 1 23 797 819 797 819 0.99 14 14 0.00058 0.035 14.4 2.6 1 23 825 848 825 848 0.98
Sequence Information
- Coding Sequence
- ATGGAGCAGCAAGTTGAGACCATTCTTGAAAAAGTCATGGAGGTGCCTGGAAATGTAGGATGTCTTCTAGCAAACAACCAAGGGCTATGTTTAGGAGCGAAAGGAAATGCGTCCGAGCATTCGGCGGGATTAATAGTAGCTATATCGAACTTGGCCTCACAACTAGATCCAAAATGCAGTGCTCCAGTGGTTTCTCTAGAGTCTTCCGATAGAGTGGTACTTTATAACTGTGATGCGGCTGTAGCATCGAACTCGAGGAAAATGGTGCGATCAGAAAGCTGCACGTTGTGCTTAACGAGTGAATCGAAATGGTTTGTAGATGTTTTCTGCGAGGACAACCAGTCAAAGGATATCGCGCTCATCATATCAAAACACCTCTGGTTCGACCTTAAACCTTGTGAAGAATGCTATGTATGTGCTGATTGCTGGAAAAGTGTACACGATTTTGATCTTTTCTACTGTAAGTTGGAAAAAATCCATCGCGAAGTGGTCAATACTTTGCCGTCCGGCACCGCTCAAAATATCGGCCAACCTGATTTCGAATTTCAGGAGATTCATGAAGTGAAAATTGAACCTCCTGAAGGAACAGAGAACGAGGATGAAGCCGCCAACGATAGTCATGGGGAGCCTTCCGCCGCCCAGCAAAACACTGGCGACGAACAGGATGATAATGAAACGTTCACCGACACGGAAAAAGAGAGGAGACCCAGAAGAAGCCGCTCCAATCCTGTAAAGTACAAGTCCGAATCCTCCAATTCAGAGTGGGACGAAAAGGATTTCCTTGCACCAGACATCCAATATGATGATGATGAACCCGACGACCATGATGATGATGATGTAGATGATGACGATGATGAGATTGACGATGACGGTTTCATAAACCATGATATACTGAATAGTAAGAAAACAGATGCTGTAGCACAAGAAACAGCAGCTGGTGTAAAAAATGAAGCCGCTGTCAGAGAAGAACCAGATGCAACCCCCGTGCCTCCGAAACGCGGCAGAGGACGACCACCTAAGCGGAGACCAGATGAAAATGTCCCTAGCACCAGCAACACAGATCGACCGAAGCAGCTCGATCATCGGGCCAAGGGAAAACGTGGCCGCAAACGTATGAAATCTATAGCAAGTAGTGATTCCGATACAGAGTACGGGTCTGACTACGAAGACACAATGAAAGTTAACAAGAACAAAAAGAAACCCCAATGCAAACGACAGGCAAGAGATGCGAAAATTTTTTCCTACATCGACGAGTTCTTCTGCTATTACTGTCCGGATAAAGTACTGTTCCAGCGTTTCCATCACGCAAATTTGCACTATAAAGAGCTGCACGATGAACCAGCCTTCCTACGGTGTCCGCGCTGTGGCAAGAAGTGTTTCACGCCGGGAGGATTTTTGAGTCACATGGAAACGCACGAAGATCCGGACAAGAACAAGTGTCCAATCTGCGGCAAAGTGACGGACCAAAAGATCACGCTCAAGAAACACATGCGCGCACATCAGGTAAAGTTAGAGGGAGCTCTACCGTATCCTTGCCAGCAATGTCCACGGAGATTTGAGCAGGAGAAGGTTCGTGATAAGCACGAACGATTGCATGGACGGAAGATTGTTATTCGAAAGGAAAAGGGTCGCGATCTGGAGGTGCTTGCGTTCTACAAACGCATCAGCTGCGACGTTTGTGAAGAAACAGGCCCAGGCTCAACTTCATTCGACAACTTTTGGGATTTAAAGGTGCACATGGGCAATGCGCACAACAAGAATCCATACCTCAAGTGTCCGCAGTGTTTCGTCAAGCTCGCCTGTCGCCAACAACTTCTGGTTCACATAGACGTGCACAACAATCCGCACAACTATCGGTGTGAAGTGTGTGGTGAAGTACATCAGAATCTCGAGAAGCACATGATCAAAGCGCACACACCGGAAACGGCGATTCCGAACGACGAAAAGAATTACAGCTGCGAACATTGTGGAAAAATGTTCAAATGTGAAACGAATCTTCGAAATCACATTGATCGTTGTCACGGTGTGAAGGACGTAAGCTGCAATGTGTGCAATAAATCTTTCAGCCGTAAGGCACTTGGTGCCCACAAACGTTCCGCACACAGCGACGAGATGTTTATGTGTGAGCACTGCCCGAAAATGTTCAAAACGCGCAGTGGACTCGAGTCACACAAAGGAGAACATGACGCAAATCTGCGCAGATCGGTCAAATGCACGCTATGCGATAAGGAGATGCGACGCGGAGCCAGCATGGCGAAACACATGAAAACGATCCACTCGCAAGAAGATCCGGTCAACTGCAATCTATGCGGTAAGGTGTTCCGCACCTCGTTCCACATGATGCGGCACCGGGCCAACACCTGCGCCGCCACCATCAATTCACGGCCGTACAAATGCGAGGTGTGTGGCAAAGGTTTCGCCATGAAGCTCACGATGACCGAACACATGACGACACACACTCGTACCAGTCTATATCAGTGTGCATTCTGCTTCAAAACGTTCGGCTACATTTCGAACCTTTACAAACATCGAAAGAAGGCCCACCCCCTGGAATGGCAAGAGGTACAAGCGCGCCCGGAAGACGGCATTGCGACCGTAATAGAAATAAGAAACTAA
- Protein Sequence
- MEQQVETILEKVMEVPGNVGCLLANNQGLCLGAKGNASEHSAGLIVAISNLASQLDPKCSAPVVSLESSDRVVLYNCDAAVASNSRKMVRSESCTLCLTSESKWFVDVFCEDNQSKDIALIISKHLWFDLKPCEECYVCADCWKSVHDFDLFYCKLEKIHREVVNTLPSGTAQNIGQPDFEFQEIHEVKIEPPEGTENEDEAANDSHGEPSAAQQNTGDEQDDNETFTDTEKERRPRRSRSNPVKYKSESSNSEWDEKDFLAPDIQYDDDEPDDHDDDDVDDDDDEIDDDGFINHDILNSKKTDAVAQETAAGVKNEAAVREEPDATPVPPKRGRGRPPKRRPDENVPSTSNTDRPKQLDHRAKGKRGRKRMKSIASSDSDTEYGSDYEDTMKVNKNKKKPQCKRQARDAKIFSYIDEFFCYYCPDKVLFQRFHHANLHYKELHDEPAFLRCPRCGKKCFTPGGFLSHMETHEDPDKNKCPICGKVTDQKITLKKHMRAHQVKLEGALPYPCQQCPRRFEQEKVRDKHERLHGRKIVIRKEKGRDLEVLAFYKRISCDVCEETGPGSTSFDNFWDLKVHMGNAHNKNPYLKCPQCFVKLACRQQLLVHIDVHNNPHNYRCEVCGEVHQNLEKHMIKAHTPETAIPNDEKNYSCEHCGKMFKCETNLRNHIDRCHGVKDVSCNVCNKSFSRKALGAHKRSAHSDEMFMCEHCPKMFKTRSGLESHKGEHDANLRRSVKCTLCDKEMRRGASMAKHMKTIHSQEDPVNCNLCGKVFRTSFHMMRHRANTCAATINSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEDGIATVIEIRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -