Basic Information

Insect: Anopheles cruzii
Gene Symbol: L
Assembly: GCA_943734635.1
Location: OX030879.1:1875069-1895287[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00012 0.0074 16.5 3.6 1 23 172 194 172 194 0.97

2 17 0.63 38 4.8 5.7 1 23 200 222 200 222 0.98

3 17 5.2e-06 0.00032 20.8 3.7 1 23 228 250 228 250 0.99

4 17 1.6e-05 0.00096 19.3 0.3 1 23 256 278 256 278 0.98

5 17 0.17 10 6.6 0.2 1 23 371 395 371 395 0.94

6 17 0.98 60 4.2 0.1 3 23 440 461 438 461 0.93

7 17 0.17 10 6.6 0.1 1 23 758 780 758 780 0.95

8 17 0.004 0.24 11.7 0.2 1 23 878 901 878 901 0.93

9 17 0.039 2.4 8.6 0.8 1 23 908 932 908 932 0.95

10 17 0.0048 0.29 11.5 1.8 1 23 964 986 964 987 0.96

11 17 1.3 77 3.9 0.1 1 23 1255 1279 1255 1279 0.91

12 17 0.00067 0.041 14.2 0.2 2 23 1288 1310 1287 1310 0.96

13 17 0.011 0.64 10.4 0.1 1 23 1317 1339 1317 1339 0.97

14 17 8.3 5.1e+02 1.3 0.8 2 20 1347 1365 1347 1368 0.93

15 17 0.035 2.1 8.8 0.3 2 23 1551 1572 1550 1572 0.95

16 17 0.0032 0.19 12.1 0.0 1 20 1582 1601 1582 1605 0.94

17 17 0.035 2.1 8.8 0.2 1 23 1613 1635 1613 1635 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00012	0.0074	16.5	3.6	1	23	172	194	172	194	0.97
2	17	0.63	38	4.8	5.7	1	23	200	222	200	222	0.98
3	17	5.2e-06	0.00032	20.8	3.7	1	23	228	250	228	250	0.99
4	17	1.6e-05	0.00096	19.3	0.3	1	23	256	278	256	278	0.98
5	17	0.17	10	6.6	0.2	1	23	371	395	371	395	0.94
6	17	0.98	60	4.2	0.1	3	23	440	461	438	461	0.93
7	17	0.17	10	6.6	0.1	1	23	758	780	758	780	0.95
8	17	0.004	0.24	11.7	0.2	1	23	878	901	878	901	0.93
9	17	0.039	2.4	8.6	0.8	1	23	908	932	908	932	0.95
10	17	0.0048	0.29	11.5	1.8	1	23	964	986	964	987	0.96
11	17	1.3	77	3.9	0.1	1	23	1255	1279	1255	1279	0.91
12	17	0.00067	0.041	14.2	0.2	2	23	1288	1310	1287	1310	0.96
13	17	0.011	0.64	10.4	0.1	1	23	1317	1339	1317	1339	0.97
14	17	8.3	5.1e+02	1.3	0.8	2	20	1347	1365	1347	1368	0.93
15	17	0.035	2.1	8.8	0.3	2	23	1551	1572	1550	1572	0.95
16	17	0.0032	0.19	12.1	0.0	1	20	1582	1601	1582	1605	0.94
17	17	0.035	2.1	8.8	0.2	1	23	1613	1635	1613	1635	0.95

Sequence Information

Coding Sequence: ATGGCAATGAGGATGCTCTACCGCGGACCGAGCACCCGACTGGAAACGTTGATTGAGAAGATTCAGCAAAGTACGCACGGCCCCGGCATGATCGCTCCCGGCGCCATTGCCGGTTTGAAAGATTTCGCCCTCGGCCAAGAGCTCTACTCCCCGCACACGTCCTCCAGCTTTTCGCCCTCGATGTCGGACGGAATGGCCACCCCAAACTCGATCACGCACGACGGTGGTGCCGCTCACGGCGGTCCCGAACCGGATGCTGCTGAGGTGGGTTGTGGAGAAAAGTCCAGCTTCCGTGCGGCCGGCAACAACCCGTCACAGATCGGGCACCCTCATCATCACCCGCGGCACCATCATCTTCACTACCACCATCGGCGATCGGGCGGCGGCGGCGGAGGCCACCCGAAGGAGGGCAAAATGTCGCGGAGTCACCACCATCACCACAACAACAACAATAGTAGCAGCCACAACAACAACAATCACACGAACAGCAACAGCAAAAACGTGGACGGCACCTATCACTGTCAGTTCTGCGACAAGACGTTCCCGCGGCTCGGCTACCTCAAGAAGCACGAACAGAGCCACACGGAGCACATGCCGTTCAAGTGCGAGTACTGCGCGCGCCTCTTCAAGCACAAGCGGTCCCGGGATCGGCACACAAAACTTCATACGGGCGATCGCCGTTATCGCTGTCTGCACTGCGAGGCCGCCTTTTCGCGCAGTGATCATCTGAAGATCCACATGAAAACGCACGACAACCAGAAGCCGTTCCAGTGTACGATCTGCAACCGGGGCTACAACACGGCGGCCGCACTGACGAGCCACATGCAGAACCACAAGAAGCAGCTGGCGCTCACCGGTAGCCCCAACCTCACGTACAGTCCCCGGTCGACCACCAGTTCCCTGTCGAGTGGCGGAAGCAAACGGGCCGCAAAGTTCTCGCCCTACGCCACCAACTCGAACCACTCCGCCGCCGATCCACTGGCTCTGTTGGGTGGACGCACCGGTTCAAAGCTGGTGCTGGCGAAGGGCTCCATCCAGTCGAACGCGAACCGAACACCGACCCCCGGTGGTGGTGGCGGAGGCAAGGGTGCCGGATCGGAACCGGATCCGTTCGCCTGTCCGTACTGTACCCGGAAGGACTTTAGCAGCCTGGAGCAGCTTGGGCTTCACGTCCAATCGATGCACGGTGGCCCTCTCGGTGGGGTGGTTCTGGGTGCCGCCGATGGTTACTTCGCTCCGCAGCGTGTCCGCCGTGCTGTGACCCCTGACGGAGGGGGCACCACGACCACGACGACGACGACGTACCCTCCCATAGCGTGCGAGTTCTGTACGATGAAGTTCCCCACCGTGCCGCTGATGTTCGCGCACCTGAAGGCGACCCACTTGGACCGGCTGGCGGCAGGACCCGCCCCGCATCGGGTGTCACCGAACGGAGCCCGATCACCCGCCGGGATGCGCCCGTCCCGGCTGTCCGGTGGTTACCCGTCGCTGGAGCACCTTCAGTTTAACACCAAAAGCCTCCTCAGCAGCACCTTCTCGTCGCTTTACGGCGGATTAGGAACCGGAGCTCCTCCTGCGACCACCATCAAGTCTGAGTTACGGTCCACCACCGATGGAACGGTTCGGAGGGAGCACGACGACGACGATGAGGAAGATGAAAGCGGCGCAGAACCGGACCGAAAGCGGCGTCGAAGGGAACCGCGAAACGAAGAAGATGATCCACTCGACGGCGATGACGATGACGATGCAGAGGACGCCATTGAGGACGAAGATGAGCGTGCGGCTTCTGCGATCGGTGGCGAGGAGTCCGAAATCCGCAGTCCATCGCACAGCGGTGGACCCGAAAATGGAACCATCAAGCAGGAACGGAAGGACACGGAACCGGGAGCTACCTCAGGGAGTGCCTCATCATCATCGGCCCGTTCGTCACCGTACGAGGCACGCGGATCCGGATCTCCACGGGCGCCGTCGCAGCCCGTCCGAGAGGGCCTCCCGGCGGAGCAGCTTACCCCGACCGATCTCAGTCAGCCGAAGATGAAGCGCCTCAAGCTGGAAGCCCCCGACGAGCAGCCTCCGGAGGGTGAACCCGAAGTGAGGAAGACCGCCGCGGAGCGTCCACCGAGCCAGCAGCGTCGTCCACGCGCCGCACGGCGGGAGAGTGAAACGCGGGGTGAACCACACTCGCTTACTTCACTGCCGCAGCACCGGATGGCGCTCCATCCCCAATCGTCCGGTCCGCCGGCCCCATCCTCATTGGCCCCTCCAGGAGCCTACCTTTGCAACCAGTGCAATGCGGCGCTGCCCGACTTTGAGTCCTTTCGGGCGCACCTGAAGGCGCACCTGGAACAGAACAGTGCCAACTGCCTGGCCGCTATGGCCGGCTCCACGTCGTCCGCCACGGCCGGTGCCCTTTCGCTGTCGACGTTCCTCTGCCAACAGTGCGGGGCCACGATGGGCTGCCAGGCCGAGTACGAGCAGCACACGATCGGTCACTTCCTCGTCACCGGCGTCGAGTATCGGTGTCAGGCGGGCGGCGGTGCCACTTGCCAGTCCGCCCTGGGCGGGAAGAATGCGTTCGCGAAGGTCGAAGAACTCCACAAGCACCTGTACGAGGGTCACCTGCAGCTCCTGTACAAGTGTACTGCGTGCGGGGAAACGTTCGACTCGAAGGTCCAGGTGCAGGTCCATTTTGCGGTGAGTCACTCGCTCGAGGTGAAGCTGTACCGGTGCTCCGGATGCGCCGAAGCCACCTTCCGCACGGAGCGCGACTTTCGTCAACACATCCGCAGTCGCCATCTGACGGGCGGCGCCGTGCAGTGTATGTTCTGCCGCGTGGTCTGCTCGTCGGAACTCGAGATGCACTTTCACCTCGCTTCGCACGCCCGCAAATACAAATGCCCGGCCTGTCCCGAGTCGTTCCACGTGGAGTTTCTCCTCGATCGGCACCTGCAGACGCACCACAGCCAGAAGGAACTGGCTTCGCCGAGCCGGCGCAGTGGGGAATCCAGTTCCGGCGCTCATCAGAACAGTGCCGCTCCAACGTCAACGGCCACGGCGACCACGACGCCATCGAGCGGCCTAGACTACCTGCAACTACACGGCCAGATGGCAGCGATGGCCGCAGCGGCAGCCGCCGCTTCCGGTGGCTGGCCTACGCTCTACCAGACGGCCAACAAGTTCTACGGCAACCAGCTGCACGTGGACACGCTCGGCGGAATGAAGCACCCGCAGCAACTTCTGCACGGGTTCTACGACACCATGCTGGGAAAGGCCACGGCTACGAGCCATCAGCATCAGCACCCGCGGTCTGCGTTCCTGCCGGAGACCGCGGCCGTCACGGCCTCGAACGTTCCTCCGGCAGCCGGCGCCACCGCCAGTAACAAATCGAACCCGTTTCTCAGTCTTTCACCTAACGCGACCGCTGCCAATCCGCTGCTGGGATTGGGCTATGGTTCCACCGGCCAGATCTGCCCGGCAAATGGGTTGTATTCTCCCGAGACCACTACGGGTGCCGCCGTTCCCACCAACGGTGCAACGGCGAGTTCCACTCCAGGAGGCTCCAAGCTTTACTCCCCAATCGGCAGCCTGTGCCACTCACGGTACACGGCCGAAAACGGTCCCGGTGGACCCGCTACTGAGTCACCCAAACTGAACGCCCCACAAGCGTCTTGTACCGGGTCCGGGACGACAAGTAAGGGGTTGACAGGTTCCGCCCCGTCGAGCAGCGGACCTCCACCACCGCTGACTTCCGGCGGCGGTAGCTACAGTTGTGGCATTTGTGAGCGCACCGATTTCGGGACCGAAAGTGAGGTCCAGACGCACCGCAAGATCGTGCACAACCTCAAGACGGGCGTCAGTTTGCGGTGCGCGTACTGCAACGGGGATTTCCGGTCCAGGAACGAGCTGGAGAACCACATGAAGATCGCGCACAATACGGGTGGCGGCAAGCACAAGTGTTTGATTTGCGACGAAATCTTCCCATCACCCGCCGTCCTGGCCGAGCACAAGCTGTCCCACTGCAAGGTCGGTGCGTCCGGGCGCTGCTCGCACTGTGCTCTGCCGCTCCCGGATGCTCACACCTTCAAGCAGCATCTCCCGGCGCACCAGCCGCAGGTCGCTGGTGGTTCCTCAACTCCGGCGGCTGCTGGCCAGGCGGTCCCTTCGTCGGCAGATCGGTCCGCCACCGGTGGCACTGCTGGGCCCAGTGGAGCATCTTCTGCGCCCTCCAACGGTACGAGCGGTACGACGAGTAGTACCGGTGGTGGTGGATCCGGCTCGGAACAGGATCGGTTCCCGCAGCAATGCATCTGCTGCCGGCAGACGCTAAACTCCGAGTTTGAAATCAGTCTGCACGCCAAATTCCACACCAAGTCACCGGACACGAACGAGCGGACGTGCGCCCTCTGCCTGGAACCGTTGCCATCGCAACCGGAAGCGTCGGCGACTAAGATCTGCGATCCGTGCCTCAAGCGACACAACTTCCCGTCCAAGCTGCTGTCGATGAACTTTCTCAAACCTCCGACGACGGCCACGGCCACCAGTGTTCCGACCGCTACTACAACTACCGCTACGACAACCCTCTCGTCGTCCCATCATCATCGAATGGCCACCTCACCCGAACCCACCCTTGGGTCGTCTCCACCGTCGGTACAGTGTAACCTGTGCAGAAAGGCGCTCCCGTCGGCGCACAAACTGCAGGAGCACCTGATCGATCACACGTTTGCCGGCTGCGAGGAGCGTGGCTACGTGTGCTACATCTGTTCGGCCGTCTTCACCTCGTCCGCCGGCCTGCAGGCCCACCTGCCGGTGGCGCACTCGAACGCGACCGCCAAACCGTACGACTGCGAGCGGTGCGGTGTGGCGTACTTCTTCCGTGCCGAACTCGAGCACCATCTGGCCGAGCACGAGCTGGGACGACGAGAAGAAGAAGACCAGCAGTGGCCAGCAGCAGTGGCCGTGGGAGGAAGCCACATCAAGCAGGAACGGGCCGAAGACGAAGAGGAGCTGGTCGAAGAATGCGGAATGCTGGAACCGGGAGGGATCGCTGGTGATGGAGAGGCTGAAGAGAACCAAGAAGATGGACAGGATGAAACGGATACGGATGCCGATACGGAGACGCTTCAGAATGAACTTCCTCCGAACAGTGGCGATGACGATGCTGATGCTGATGCTGATGAGGATCATCAAGAGGAGATGGCCGTCGAAGACGAAGCAGAACCAGCGGAAGATGATGGCGACGTGGAAGAGGAAGAAGAGTACATCGAGGTGGAACACACGGTGCTGGAGGAGTCAACCACCCGCGCGACCAACGCGATCGGCTACGGAAAGGATCCGCGATCAGCGATATCCGCTTCACCGTCGCTCGTCACCGTCACTGCAACGGAATAA
Protein Sequence: MAMRMLYRGPSTRLETLIEKIQQSTHGPGMIAPGAIAGLKDFALGQELYSPHTSSSFSPSMSDGMATPNSITHDGGAAHGGPEPDAAEVGCGEKSSFRAAGNNPSQIGHPHHHPRHHHLHYHHRRSGGGGGGHPKEGKMSRSHHHHHNNNNSSSHNNNNHTNSNSKNVDGTYHCQFCDKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGSKRAAKFSPYATNSNHSAADPLALLGGRTGSKLVLAKGSIQSNANRTPTPGGGGGGKGAGSEPDPFACPYCTRKDFSSLEQLGLHVQSMHGGPLGGVVLGAADGYFAPQRVRRAVTPDGGGTTTTTTTTYPPIACEFCTMKFPTVPLMFAHLKATHLDRLAAGPAPHRVSPNGARSPAGMRPSRLSGGYPSLEHLQFNTKSLLSSTFSSLYGGLGTGAPPATTIKSELRSTTDGTVRREHDDDDEEDESGAEPDRKRRRREPRNEEDDPLDGDDDDDAEDAIEDEDERAASAIGGEESEIRSPSHSGGPENGTIKQERKDTEPGATSGSASSSSARSSPYEARGSGSPRAPSQPVREGLPAEQLTPTDLSQPKMKRLKLEAPDEQPPEGEPEVRKTAAERPPSQQRRPRAARRESETRGEPHSLTSLPQHRMALHPQSSGPPAPSSLAPPGAYLCNQCNAALPDFESFRAHLKAHLEQNSANCLAAMAGSTSSATAGALSLSTFLCQQCGATMGCQAEYEQHTIGHFLVTGVEYRCQAGGGATCQSALGGKNAFAKVEELHKHLYEGHLQLLYKCTACGETFDSKVQVQVHFAVSHSLEVKLYRCSGCAEATFRTERDFRQHIRSRHLTGGAVQCMFCRVVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHLQTHHSQKELASPSRRSGESSSGAHQNSAAPTSTATATTTPSSGLDYLQLHGQMAAMAAAAAAASGGWPTLYQTANKFYGNQLHVDTLGGMKHPQQLLHGFYDTMLGKATATSHQHQHPRSAFLPETAAVTASNVPPAAGATASNKSNPFLSLSPNATAANPLLGLGYGSTGQICPANGLYSPETTTGAAVPTNGATASSTPGGSKLYSPIGSLCHSRYTAENGPGGPATESPKLNAPQASCTGSGTTSKGLTGSAPSSSGPPPPLTSGGGSYSCGICERTDFGTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCALPLPDAHTFKQHLPAHQPQVAGGSSTPAAAGQAVPSSADRSATGGTAGPSGASSAPSNGTSGTTSSTGGGGSGSEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPEASATKICDPCLKRHNFPSKLLSMNFLKPPTTATATSVPTATTTTATTTLSSSHHHRMATSPEPTLGSSPPSVQCNLCRKALPSAHKLQEHLIDHTFAGCEERGYVCYICSAVFTSSAGLQAHLPVAHSNATAKPYDCERCGVAYFFRAELEHHLAEHELGRREEEDQQWPAAVAVGGSHIKQERAEDEEELVEECGMLEPGGIAGDGEAEENQEDGQDETDTDADTETLQNELPPNSGDDDADADADEDHQEEMAVEDEAEPAEDDGDVEEEEEYIEVEHTVLEESTTRATNAIGYGKDPRSAISASPSLVTVTATE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -