Basic Information

Insect: Anopheles cruzii
Gene Symbol: -
Assembly: GCA_943734635.1
Location: OX030880.1:86746980-86750968[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.2e-05 0.00076 19.6 1.4 1 23 177 199 177 199 0.97

2 14 0.058 3.5 8.1 5.3 1 23 205 227 205 227 0.97

3 14 0.0012 0.073 13.4 0.4 2 23 401 422 400 422 0.96

4 14 0.0032 0.2 12.0 0.5 2 23 429 451 428 451 0.96

5 14 1.1e-05 0.00065 19.8 0.1 1 23 502 525 502 525 0.96

6 14 0.0084 0.51 10.7 3.4 1 23 571 593 571 594 0.95

7 14 0.14 8.8 6.8 1.0 3 19 603 619 601 620 0.92

8 14 0.016 1 9.8 9.8 1 23 629 651 629 651 0.95

9 14 0.0067 0.41 11.0 0.4 2 23 657 678 656 678 0.97

10 14 8e-06 0.00049 20.2 1.5 1 23 684 706 684 706 0.98

11 14 0.0011 0.065 13.5 0.1 3 23 714 734 712 734 0.97

12 14 0.00035 0.022 15.0 0.3 3 23 742 762 740 763 0.95

13 14 1.6 95 3.6 0.0 1 23 777 799 777 799 0.94

14 14 0.015 0.94 9.9 1.2 1 20 1283 1302 1283 1305 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.2e-05	0.00076	19.6	1.4	1	23	177	199	177	199	0.97
2	14	0.058	3.5	8.1	5.3	1	23	205	227	205	227	0.97
3	14	0.0012	0.073	13.4	0.4	2	23	401	422	400	422	0.96
4	14	0.0032	0.2	12.0	0.5	2	23	429	451	428	451	0.96
5	14	1.1e-05	0.00065	19.8	0.1	1	23	502	525	502	525	0.96
6	14	0.0084	0.51	10.7	3.4	1	23	571	593	571	594	0.95
7	14	0.14	8.8	6.8	1.0	3	19	603	619	601	620	0.92
8	14	0.016	1	9.8	9.8	1	23	629	651	629	651	0.95
9	14	0.0067	0.41	11.0	0.4	2	23	657	678	656	678	0.97
10	14	8e-06	0.00049	20.2	1.5	1	23	684	706	684	706	0.98
11	14	0.0011	0.065	13.5	0.1	3	23	714	734	712	734	0.97
12	14	0.00035	0.022	15.0	0.3	3	23	742	762	740	763	0.95
13	14	1.6	95	3.6	0.0	1	23	777	799	777	799	0.94
14	14	0.015	0.94	9.9	1.2	1	20	1283	1302	1283	1305	0.91

Sequence Information

Coding Sequence: ATGGATCAGAAGTTTATATTGAGGCAAGTGGGCAGTCAGGCGGCTTCCTCTGTTCCGGTGAGCGTCAGCCAGCTAAAAATCATCTCTACTGGTCGTGGTGCTTACCATCAGCACCAGATCGATCCGCAGGCCACCGCCACTATCATGAGTGAACCGATATTGCTACAGATCCACGACGGCAAGCGGTATCTGGTGGACGAGAGCGCGATACAAAACATCGACCAAGTGCCACCGGAAAATCTGATCTACATGAACACCGAGAACATGGGCTCCGAACAAGGGGAGTCGCTGACGGACGAACTGGTTCCCGAGCCCTTGGCCGAGTGCGAACAGCAGCAGCAGCAATATATGGAGTGTGAAGTGACCGAGGAAGTGATCACGGACGACTGGGTGCAGTCGCAGGGCGACCAAGAGTGCGTCCAGGTGACGGTCGATCAGCTCGGTTCCACCACGGTGATCGGTGCGGCGACGGTGGAGGACGAAATACCCGTGCCCCTCGATCAAGACGAGTACACTCTTTCGCGCCCCTTTCCGTGCGATTTCTGCAGTCGGCGCTTTCGCAAAAAGGCCAACCTGAACACGCACATGATGGGACACTCGACTTCCCGGTATTTCGCGTGTAAGCTGTGCCATACGCATTACCAGCGGCGCACCGATCTGTTGAACCACCTTCAGCAGCACGCCTTCTCGACGGACGATCACGACGACCCGCCCTTTATCGGCGAGCAAGGATCCGAGTATGACACACCACCGATGCAAAGCCAAGGTGGCCATCACCAGCGTACGCGCAATTCTAGCGACGAAGAGGACATGATGTTTGGCGAGACGGCTGCTGGCGTGAGCTACAATTCGCAGCCACCGTTGCAGCTAATATCGACACCGACCTCCTACAGTGGCCAGGAACTCCCAGCCACCACTAACAGTGCCATAGGAAATGCGCCCAATTCACTGCTGTATTCAGTTCCTTCATCACCCTTCACCCTGTTGCCGCCGGCGTCCGGCGTCGTTGCTTCCAGTTCCGGTACTGGCAGCAACGTCCGTAACCGACACCATTCCTCGAAGGCTGGACGATCCGCAAATCGCACAGCGCCGCCCGCCAGCAACCGGATAAAACAAGAACCCAGCTCACCGACTGACGGAGTCAATGAGGTGTTGCCGACGGCGGTCCGATTCCCGGTGACGGACCCGCGCAAACCCTGTGTCTGCCAGCAGTGCGGCATGGGGTTTGCGCGGGAAAAAGCACTGGCCTCGCACTCACGGGTCCACGGCGGAGATTCGAAGATCGAGTGCGACGTTTGTGGGGAAACATTCTGGAACCACACACTGCTGCAGGGCCATATGCGGCAACGGCACACCATTTCCCCAATCGGCACCGGCACCGGGTTTTATCCACGAGCAGCGAGAGCGAAGCGTAGGCCACCGATCGCGACCCATCAGCCGCCGGTTGGCGATCCCGGTGGCGATCCCGGGGCGAGTTACTGCGAGTTGGTGCTGGGAGTTCAGTATAGCTGTGATATTTGCGGGCTGATATTTTCCCAGGCGGATCACCTGCAAGGCCACATTCAGCAGGTGCACGGAACGGTGGTCAAGCAGGAACTGAACGGCGGGGACCTATCGTCGGACGGTGAGGAGCGTGGCGACACCGAATGGATGGAGCTGGAGGGGTCCCCGAATGCGGTGTCGTCGCTCGAGCCGCAgcgccagcaccagcacaagtgccagctgtgtggggaatcgtttccgaacgagcacagcattcggggccacttgcaggagcaccatcggcaccagctcaccagtacgtcctgtgtggcgtgtggcaagcagtgcaagaactcgaccacgctcatgaagcacgcctgggaccattcgcgcgtcaaggcgcactgctgcgcgatgtgcgataagacgttccaccacaaggcgcgcctcaagcgccacatggactcgcaccgcaacaagacggtccggtgtgaggtgtgcggcgaagacttcccggacgggcgcaccctcatgaaccatcggcactcgcacacgaaggcgaacaagttcccgtgccacacgtgcggcaaaacgttcggttctcgctcctcgcagcagatacacattcgcattcacacgggcgaacgaccgtacggatgtcggtactgctggaaggcgtttgcggacggcggaacgctgcggaagcacgaacggatacacacgggcgaaaagccgtacggttgttcggtgtgtccgaaagccttcaaccagcgcgtggtgctccgcgagcacatccgtgcccatcactcgcaggtcgacccgaagcggaccgcgGACAAGCTGCCCTACTTTTGTCCCGTGTGCAGTGTGCTGTTTGGTGCGGCCGACGAATTCGTGCAGCACCTGATCGAGCACAGCGACCAGACCACGGCCATGAAGCGTAAAACGCCAACGTTCCCGCGGAAGTACAAACGTCGCCGGAAGTTGAAACCGCACGAACTGGAGCGATTGCAAAACGGGCGGCGCAAGAAACcggccgttggcaccgggcccgaaccgagatccgcagctgatgacgacgacgacggcggcgaggaggacgatgactatgattacgacgacgatggggacgatgatcgcgaacaggaccgatcggatacgaccacggccagctgcaacaattcgttcatgtcactggaaaacactgacgggacgctgaaaaccccgaacgagttGTTTGTGGACTATGGCGGAACCGTCGGGAAACTGATCGCCTCGCCAAAGTTTGTCTCTCCGTTCGAGCTGCTCGCCGATCTGGAACCGGCGACCGCGGCGGGGAAGGCTGCTGCCGGTCGCCGACAACCGAACGTGATGATGCTGGACGACAGTGGCATCAATCTGCTCAGTGAGGTGGTGCTCGCTCACGGGACCTCAGCGGCGGCCACAGATGTTGGTGGGCCACCGACATTGAACAATAACTATCGTGATGTAGTAGAATCTCCCCGCCAGAAATCCGCCAACCGGAAACGGGTGCTGAAGGCGAAGCCGGCGACGTCGGTCAGCAGGACTGGGCCACGGATGATACATTCACAAAAGGTCAGACAAGCGGCCACGCAGAGTGAAGCCGGCAGCAAACGTGGTCGGGGCGGTGCTAAACCAAGTATTGGGACCCGGAACAAGAAGGTTGCGTCAAACATCGGTTCATCAGCTTCGGAGTATGTGGTGACCAACGACGACATGACGAAGGACGATGTGACCTCAGCGTGCGCCGAAACCAGCCTCATCTTCAGTGCCAGTGCCGATATTGGGCCCACAAACTTGAAACATGAAAGCGCAGCTGACCAGCCAGGGCACTGTGGCGAACGACGTAATGGCAAACGGCGGCGCCCGGTGAAGTCAGTGACCCGGCTGCACCCATCTCCGTTGCGGAGCCAAAGACTAACACGACGGCAGCTTGAACGGGAGGTCAACTTCCTGAAGGAAGCATTTGCTGCCAGCCCGTCGTCGCCGGAAAGACTGACCACCACCACAGGAGAGGACCAGGCACCGGGAGGTGATGGTAAAACGATCGATCGCGAGAACATTAAACAAGAAACGGCGACAAACGCCTCCGAGAGGCTGGCCGAAATGCTACTGAACGATCAGATTCCAACGACCATTAGCAGCAGCACCGACAACAGCCATCACAGGCTCTCTGTCAAACCAGAGGACCAAACGTGGGAGGAAGATAGAGCGGATCATCGGTGCCAGGTCGGGACAAAGGAAGACGCAGAGTTTGGTTGTATTTATACGGATACGGATACGGATACGGGAGAGGAAGTGGACCCTAGTGAGATCGAACGGATGATGCGAAGCGCCGCCGACCATTGCTGCTCCATATGTGGCCAGTATTTTGACAATCGTGCACAATTGCTCCTCCACGTACCGGTACACATCTAA
Protein Sequence: MDQKFILRQVGSQAASSVPVSVSQLKIISTGRGAYHQHQIDPQATATIMSEPILLQIHDGKRYLVDESAIQNIDQVPPENLIYMNTENMGSEQGESLTDELVPEPLAECEQQQQQYMECEVTEEVITDDWVQSQGDQECVQVTVDQLGSTTVIGAATVEDEIPVPLDQDEYTLSRPFPCDFCSRRFRKKANLNTHMMGHSTSRYFACKLCHTHYQRRTDLLNHLQQHAFSTDDHDDPPFIGEQGSEYDTPPMQSQGGHHQRTRNSSDEEDMMFGETAAGVSYNSQPPLQLISTPTSYSGQELPATTNSAIGNAPNSLLYSVPSSPFTLLPPASGVVASSSGTGSNVRNRHHSSKAGRSANRTAPPASNRIKQEPSSPTDGVNEVLPTAVRFPVTDPRKPCVCQQCGMGFAREKALASHSRVHGGDSKIECDVCGETFWNHTLLQGHMRQRHTISPIGTGTGFYPRAARAKRRPPIATHQPPVGDPGGDPGASYCELVLGVQYSCDICGLIFSQADHLQGHIQQVHGTVVKQELNGGDLSSDGEERGDTEWMELEGSPNAVSSLEPQRQHQHKCQLCGESFPNEHSIRGHLQEHHRHQLTSTSCVACGKQCKNSTTLMKHAWDHSRVKAHCCAMCDKTFHHKARLKRHMDSHRNKTVRCEVCGEDFPDGRTLMNHRHSHTKANKFPCHTCGKTFGSRSSQQIHIRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYGCSVCPKAFNQRVVLREHIRAHHSQVDPKRTADKLPYFCPVCSVLFGAADEFVQHLIEHSDQTTAMKRKTPTFPRKYKRRRKLKPHELERLQNGRRKKPAVGTGPEPRSAADDDDDGGEEDDDYDYDDDGDDDREQDRSDTTTASCNNSFMSLENTDGTLKTPNELFVDYGGTVGKLIASPKFVSPFELLADLEPATAAGKAAAGRRQPNVMMLDDSGINLLSEVVLAHGTSAAATDVGGPPTLNNNYRDVVESPRQKSANRKRVLKAKPATSVSRTGPRMIHSQKVRQAATQSEAGSKRGRGGAKPSIGTRNKKVASNIGSSASEYVVTNDDMTKDDVTSACAETSLIFSASADIGPTNLKHESAADQPGHCGERRNGKRRRPVKSVTRLHPSPLRSQRLTRRQLEREVNFLKEAFAASPSSPERLTTTTGEDQAPGGDGKTIDRENIKQETATNASERLAEMLLNDQIPTTISSSTDNSHHRLSVKPEDQTWEEDRADHRCQVGTKEDAEFGCIYTDTDTDTGEEVDPSEIERMMRSAADHCCSICGQYFDNRAQLLLHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -