Basic Information

Insect: Anopheles cruzii
Gene Symbol: -
Assembly: GCA_943734635.1
Location: OX030879.1:11826965-11830034[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0051 0.31 11.4 6.7 1 23 232 254 232 254 0.98

2 11 3.4e-06 0.00021 21.4 0.1 1 23 287 309 287 309 0.98

3 11 2.3e-07 1.4e-05 25.1 1.2 1 23 315 337 315 337 0.98

4 11 8.6e-07 5.3e-05 23.3 3.5 1 23 343 365 343 365 0.98

5 11 0.00015 0.0092 16.2 0.6 1 19 371 389 371 392 0.95

6 11 1.3e-05 0.00081 19.5 0.8 1 23 398 420 398 420 0.98

7 11 1.5e-07 9e-06 25.7 1.1 1 23 429 451 429 451 0.99

8 11 8.1e-07 4.9e-05 23.3 0.7 1 23 457 479 457 479 0.99

9 11 0.00051 0.031 14.5 0.7 1 20 486 505 486 505 0.96

10 11 0.0002 0.012 15.8 1.1 1 23 611 633 611 633 0.98

11 11 8.2 5e+02 1.3 0.1 1 10 680 689 680 693 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0051	0.31	11.4	6.7	1	23	232	254	232	254	0.98
2	11	3.4e-06	0.00021	21.4	0.1	1	23	287	309	287	309	0.98
3	11	2.3e-07	1.4e-05	25.1	1.2	1	23	315	337	315	337	0.98
4	11	8.6e-07	5.3e-05	23.3	3.5	1	23	343	365	343	365	0.98
5	11	0.00015	0.0092	16.2	0.6	1	19	371	389	371	392	0.95
6	11	1.3e-05	0.00081	19.5	0.8	1	23	398	420	398	420	0.98
7	11	1.5e-07	9e-06	25.7	1.1	1	23	429	451	429	451	0.99
8	11	8.1e-07	4.9e-05	23.3	0.7	1	23	457	479	457	479	0.99
9	11	0.00051	0.031	14.5	0.7	1	20	486	505	486	505	0.96
10	11	0.0002	0.012	15.8	1.1	1	23	611	633	611	633	0.98
11	11	8.2	5e+02	1.3	0.1	1	10	680	689	680	693	0.78

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATCGATCAATAAAAATAAGATCTTTGCGAGGCAAAGGTACGGCAACAGCAACAACGACATTTGCCGCCTGTGTCTCAAGAATGAGGCGCACATGGAACCACTGTTCTACGCGAATCTGTTCCCGAACATTTTGCTGACGAAAAAAATCTACGACTGCACCTCGATTCAGATACTTTACGAGCGCAATCTGCCGATGTTCATCTGCAAGCTGTGCGCCAACAAGCTGGACGAGTACGTGCGCTTCCGGGAGCGCTGCATAGCGAACGATGAGTTTCTGCGCAACGCCCTGGCCGCGTTCGACCTGGCCGGAAGCTGTGGCGGCCCGGCTGGCAGCGTACCGATGATCAAAATGGAACCAGAAGACACGCCACCACCGCCGGCGAAGCTCGCGCAGTGTCTGGGAGTGCTACCGATGGAGCTGAACTGTGCGCTGGTGGCGGCAGCGACGGCCGCGGCCACCCACGGGCACCAGGCACCCGGGCACAAACAGGAACCGCCGGATGAGGAACTGGACCGATCGGAGTTTGGCTGCGGGGACCCGCTGGAAGACGGCTGCCGGACGACGCTGAACCGGAACCGGCTCCCGGGCAGTGAGGCTGCGTCGGGCGATGACGACGGGGAAGAGGAGGACACCCTGGAGGATGATGCCGAGGGCGAGGAGGAGGATGATGGCGGGCGGTACGTGTGCGAGGTGTGCCCGAAATCGTTCAAAATACACCACCATCTGCTCGTGCACAGTCACACGCATTTGAACCATCAACCCTCGGTTCCTTCTTCGGGTGGCGGCGGTGGCGGCGCCGCCAGTGTCGGGATCAGCGGCACGGATGGCGGTGGTAAGCagtcgtacgcgtgcccgaagtgtgccaaagtgttcgtcaaccggggcaacttgctgaaccacctggaaacgcacacgaacgagaagagttacagttgcgacatctgttcgaaatcgttcaagtacaacgtacagcttcggttacatatgcgcatccacaccggcgaacggccgcacaagtgtgaaatctgcaaccgcggcttctcgcagctctccaatctgCGATCCCACCGGAAAACGCACTCCAAAgtcaaaccgtacaagtgccatttgtgtctgaagagctttaccgtgctggacaacctgacggcgcacagtgccaagtgcttgaaggacaagttccggtgcacgctctgctcgaaatcgttcgccaaggagggaaacctcctgtcgcacctgcagtcccacagcgagggcatcgtcgagaagatgttcaagtgcgagatgtgcccgaaaagctttaagaacaaggaggactggaagcggcacgtgcgcgtgcacacgggcgaaaagccgtacacgtgcgatatctgctcgaaggggttcgcccagaaggcgaatctgttgtcgcaccggaagacacacctcaagccgaccgtggtcttcaagtgcgaccggtgcgatcggacgttccgatcgcagaaagtgctcgaggtgcaccggcccaagtgtaccggcgaatcggcgccgtccgagtCGACCCAGGGCTCGCCCAGTCCGGTACTGGCCACCACACCCCCGGTCACCACCACGACGGGTACGACGATGGCGACGACGGCGCTGACTGACTCCACACCACCGAGCCTCTCGGAAGCCCTGTCCGACCTGTTGCGCTACGAGATTGCGCTGAGGGCGCCGCTCGAACTGCAACAGATGTTGCTGGGCCACATGGACCGAAAGAGCAACGGCGTCGGTGGTGGTGGTGGTGGTGGGGCCGCTGTAGGTGGCCACCACGGTAAGGCCACCTCGGGGCGTCGCTATCGGTGCGACGTGTGCTTCAAGggttactcgcagtatccttcgctgatcaagcaccggaagctgcacttcaaggtgccgccgctggtgaaggtgctcgcttcgaaggctgctgctgctgctgccgtcgctgccactgccactgccaaagacgcggcggccgtacgcgacaccggcccggaaccgtcactatccgccgagcgcccgtacagctgtgatatttgtgatccacgaacggcccagcagcagccgCAGCCGCAGCACGGGTCCTGGGGCGGAACGCCACCCGCCAGCGCCGTTTTGGCCGTCGGCGCCCCCAACCCGCCAATCCGTGGAGGAGGACAGCACTGTGTAACGTAG
Protein Sequence: MAEDLSINKNKIFARQRYGNSNNDICRLCLKNEAHMEPLFYANLFPNILLTKKIYDCTSIQILYERNLPMFICKLCANKLDEYVRFRERCIANDEFLRNALAAFDLAGSCGGPAGSVPMIKMEPEDTPPPPAKLAQCLGVLPMELNCALVAAATAAATHGHQAPGHKQEPPDEELDRSEFGCGDPLEDGCRTTLNRNRLPGSEAASGDDDGEEEDTLEDDAEGEEEDDGGRYVCEVCPKSFKIHHHLLVHSHTHLNHQPSVPSSGGGGGGAASVGISGTDGGGKQSYACPKCAKVFVNRGNLLNHLETHTNEKSYSCDICSKSFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTVLDNLTAHSAKCLKDKFRCTLCSKSFAKEGNLLSHLQSHSEGIVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHRKTHLKPTVVFKCDRCDRTFRSQKVLEVHRPKCTGESAPSESTQGSPSPVLATTPPVTTTTGTTMATTALTDSTPPSLSEALSDLLRYEIALRAPLELQQMLLGHMDRKSNGVGGGGGGGAAVGGHHGKATSGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLASKAAAAAAVAATATAKDAAAVRDTGPEPSLSAERPYSCDICDPRTAQQQPQPQHGSWGGTPPASAVLAVGAPNPPIRGGGQHCVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094615;
90% Identity: -
80% Identity: -