Acru010977.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles cruzii
Gene Symbol
-
Assembly
GCA_943734635.1
Location
OX030880.1:58091980-58100034[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.088 5.3 7.5 0.1 2 23 237 258 236 258 0.95
2 22 1.9 1.1e+02 3.3 0.2 1 23 264 291 264 291 0.88
3 22 0.00031 0.019 15.2 0.4 2 23 296 318 295 318 0.96
4 22 0.062 3.8 8.0 2.5 1 23 327 349 327 350 0.96
5 22 0.00024 0.015 15.6 1.8 1 23 357 379 357 379 0.98
6 22 8e-05 0.0049 17.1 0.9 1 23 385 407 385 407 0.96
7 22 0.00025 0.015 15.5 1.0 1 23 413 435 413 435 0.98
8 22 2.7e-06 0.00017 21.7 0.8 3 23 490 511 490 511 0.98
9 22 0.14 8.4 6.9 0.9 1 23 517 539 517 539 0.97
10 22 7.4e-07 4.5e-05 23.5 1.1 1 23 545 567 545 567 0.98
11 22 0.0015 0.089 13.1 3.3 1 23 573 596 573 596 0.96
12 22 0.0066 0.4 11.0 0.1 2 23 941 962 940 962 0.97
13 22 0.00041 0.025 14.8 1.3 3 23 1002 1022 1001 1023 0.96
14 22 0.0017 0.1 12.9 3.1 2 23 1028 1049 1027 1049 0.96
15 22 8.2e-06 0.0005 20.2 0.4 1 23 1057 1079 1057 1079 0.99
16 22 0.28 17 5.9 7.7 1 23 1085 1107 1085 1107 0.97
17 22 0.0056 0.34 11.3 0.4 1 23 1114 1137 1114 1137 0.97
18 22 1.9 1.2e+02 3.3 0.2 2 23 1165 1189 1164 1189 0.95
19 22 0.00075 0.046 14.0 2.4 2 23 1194 1215 1193 1215 0.97
20 22 2.1e-06 0.00013 22.1 1.4 1 23 1221 1243 1221 1243 0.98
21 22 4.7e-07 2.9e-05 24.1 0.5 1 23 1249 1271 1249 1271 0.99
22 22 0.0063 0.39 11.1 1.2 1 23 1277 1300 1277 1300 0.96

Sequence Information

Coding Sequence
ATGAATTCGCAACCGGAGGAAGGACCAATCTCCGGAGAGGCCTCGACATCAAAGGCCCTTCCTACGCCGTTAGAGAGGGCTTTGCTCCAGCGCTTCTGCCGACTGTGTATGCGAGAGTTTCCGTTTCTACTGCCGTTCAACTCATCCTTGAACAGTGTAACCATAGGCAACATGCTGGAGCGACTGCTCGGCGGATTCAATATTCAGCAAACGCTCTACCTCCCCAACGCCATCTGTTCCCGTTGCTTGACGAAGCTGGATTTTGCTTACCACGCGCAGCGGGACTTTGTACGGAATGAGCATCGCTTGCGACACTATTTGCAGCAGGGCGAGGTAGTGCAAAAATTGTTTGAATTTCAGAACCACTGCACGGCCGAGCAAGAAAGTTACGCGGAGGTGCTTCTGAAAGCGCATGGCGCCGGATTGTTGAGCGAGCGGGTTAGAGTCACAGCCGAGCATGAAGTACCGGGACTGGAGGACGCAGAATTGAAGGCGGAAGAACTTTCCAAAGCTGTGCTACCACCGAGTGAATGGGCTGTGGTGGCGTGCGACTGCAGTGCCAAGCCGAAAGCGGCCAGTCATGGCTTTCCTCGGTCGACGGATTTGCGTCCACCGAAGCGTACACTGCGCAACAGGCAGCTTTTGCGCCAAGCAATCACAGCCAGTAGCTCTCCATCTGGTGCCAACGGTTTGCCAGTTGATATGACTCGATGCTACATTTGCAACACGCCAACGGAAAGTGAGACCGCGCTCCGGGACCACATTGCACTGCACGTGGAAATGTTGCCCCATAGCTGCCCCGAGTGTAGCCTCGAGTCGCCAGTTAAACCCATCACTTCGGTGGTAATGCTGCTCCGTCACTACCGGATGCACTCGTATCCCCTCAAGTGTCCGCAGTGTCCTCAGCGCTTCACACGGTACGCCAACGTTTACGCGCACGTTCGGTACCGCCACGAAATGTTCGACAATCCCGAGGGCTACACGTGCGAAATATGTGGACTAACGATTAAGTACCGGCCCACATTTACTTTCCACATGCGCAACCATCACCACGAGTCGGCCGGCACTTTTCGTTGTACCTTTTGCGAACGCACTTTCGGCACTCGCGCACGTCTCGAACGCCACGAGCGCTCCCACACGGGAGAACGTCCATTTGCGTGTCGCTCGTGTCCAAAAACGTTCGCCCACGCAAGCCAACTAGCGGCACACAGATCGAGGCATATCAACGAACGTGGCCACCAGTGCGGAGTGTGCGGAAAGGCATTCTTCAGCAAAGCAATACTGCGCCAACATCAGCTAACTCATGAGCGGACGGCGGGAATCGTACAGCAGCCAGCAGCGGAGGACCACACTGCGGCTGCTGGTAAAACGAAAATCCGGCCTTGTACCTTTCCCGGTTGTCAGCATGTGGCGGCCACTTACCAGACGTATTATACGCACCGCTTAAGGCACGAAATGGCTCACTGGTGCGACGAGTGCGGGCGGCGATTCGCACGTCAAACGGAATTGCAGCGCCATCGAAGGATCTACCACACGACGGACCATCCTTATCGGTGCGAGCCATGCAATAAGATATTCCTGAGTCGCCAAAGCTACCGGGAACACATGGATTCGCACGCCAACGTACGACGGTTCGAGTGTGAAATTTGTGATAAGAAGTTCGTGCGACGGCGAAACCTGATCAACCATCGGATGTCCCACACAAACCTACGCCCCTTCAAGTGTGCGCTTTGTGAAAATACGTTCAAGTACAAAAGTGACTATAATCGGCACCGGAAGGAGAAACATAGCCTGCCCGAACGACCGGGTGCCAAAGGAGAGCCAGCGATTGATGCGGGAGGCGTGGACGGGATTGTACTGATGATGAACAACTCGATGGTTGAGGAAGCGTCGTTGGAAGAGGAGGTTGAAGAGCGAGTACTAGTGGAAGAAGATATCGTACTGGACACAACGTACGGGGAAGAGATTGTTACGAAATATGAAACAATCGAAACGGTAGAGGAATCGGTTGTAATTGCCCACGTAGATGATTTCTGTCGCGTTTGTTTGCTGAAGCAGCCGAATTTAACTAATGTGGTGGGCCGAATCGATGGTGTGATGATTCCGGAGATGCTGTACAAGCTGTGCGGGACGCAGATTGATGTTGACGATCGATATCCGCGCCGCATTTGTGAGCGTTGCCTGGCCATGGTGGACTGCGCGTTCAACTTCGTGAGTGAGTTCCGGCAGCAGGACGAACGGTTGCGAAGTTTCTACTGGAACGGGCCGGTTTCGAAGCAACTACAAAACTACCAGCCGCAAGGTGAACTAGAACGGAACAAGCGTATGGAAGCGCTGCTAGCTCGAAATCCGCTCCTGCACATCGGAGGAGCAAAAGAGTGGTCAACGAAGGCAACTTGCACAGATGCTCCAACCGTGCAGTGTGTAGACACGGGTGTAAACACCGACGAGGTACTGGAATTTTTGACGATGGAGAGCGTAAAGCAGGAAGGGACGGAGGAAGGGACGTCCGAAATAGAGTTGGACGACTTGGAGGATGATGAGACCAGTCAAGACATGCCTTGCGATTCCGTGGGTGCACGAAAAGAGCTGGTTTCGATGCGAATCGACCTGTTGACATCGGCTGAAGACCAGGACCACGAGGTGGTTACCGATGAGGATAACAAGCGTAAACAAACGAGGCGCTCGTTGCGTCTGAGAAAGCTGGACAACAGCTCGGAGAAGGCAAACGATCTGAGCGAGGCTGAGGAAGAGCAGTGGGAAGTGGGAAGCCAGAGCAGTGCTGACGGCGAAATGTTACCGGTTTACGACGACCGGCTGCGTTGCTACATTTGTGATTATACAGCCCGGGATGCTGAACTGTTCGAGCAGCACCTCGAAACGCATCTTCCGATGCTACCGCACGAATGTCCTGTTTGCAAGGACGCAGGGTGGTGCCTAGGGCCACTGAAATCCCTCGGGTCGTTACGAAGCCACTATCGCTCACATAGTTTCCCGCACGGCTGTAACGTTTGTGGCAAGCGATTTTCGACCGATGCGGGATTTCTGAAGCATCGCGCCACACATCACTCAGGCGAGCTGGTGTGCGAAGAGTGTGGTCGGCAGTTTCACAATCGTAAAAGCTTGGTCAATCACGTGCATCGCCACGAGGCGTTGCGGAAGGAGAGCTATAAATGTGAAATATGTAAAAAAGTGTTCGGTAACCGACCACGGTTGGTCCGCCATTTGCGCGTTCATACGGGCGAAAAGCCGTACGAGTGTCAGTTCTGCAACCGGCGCTTCAATGACTCGCACCAGCACCAGCGGCATGAACGATTTCACCGAACCGAGAAGCATGGATACCAGTGCGAAAGCTGTGGCCAAAGATTCGACTCTGAGCGCAAGCTCGGGACACATAATATGACCGCACACATGACGGCGGAGGAACAGGAAGCGTATGCCACGGAGCGCCGAAAGCGATATGAGCGGCGGATGGGCAAACTGAAGGATAGCCGATGTCCCTTCGAGGGCTGCGACTACGAGGCCAAAACGTACGGTGCAATGTACGTACACAAGCGCAGCAAACACATTCTGCGGATCAAGTGCGACTTTTGTAACAAACATTTCGCCTTCCAAAACCAACTGGAACTGCATCTGAAGCTGCACACGGGAGAAAAACCGTACAAGTGTGACATCTGCGACCGTTCGTTCCGCCGACCGTTCAGCTACCGGGAACACATGGAGCAGCACGAGTCGGACAAGAAGTACGAATGCGAAACGTGCGGGAAAAGCTTCGGCAGGCCACGCTACCTGCAAGCGCACAGACAAACCCACACGACGGAAAAGCCGTTCGCTTGCGCCACGTGTGGCAATCAGTACAAAACGAAGGGCGAGATGAAAAAGCACAGTAGGATGAAGCATGACATAGTGTTCCTGCCGGAGAAGAACGAGCAGGTCGAAGAGGCGTACATTGTTGAGTATGTGGATCCGTTCGTCGTTCTCTAG
Protein Sequence
MNSQPEEGPISGEASTSKALPTPLERALLQRFCRLCMREFPFLLPFNSSLNSVTIGNMLERLLGGFNIQQTLYLPNAICSRCLTKLDFAYHAQRDFVRNEHRLRHYLQQGEVVQKLFEFQNHCTAEQESYAEVLLKAHGAGLLSERVRVTAEHEVPGLEDAELKAEELSKAVLPPSEWAVVACDCSAKPKAASHGFPRSTDLRPPKRTLRNRQLLRQAITASSSPSGANGLPVDMTRCYICNTPTESETALRDHIALHVEMLPHSCPECSLESPVKPITSVVMLLRHYRMHSYPLKCPQCPQRFTRYANVYAHVRYRHEMFDNPEGYTCEICGLTIKYRPTFTFHMRNHHHESAGTFRCTFCERTFGTRARLERHERSHTGERPFACRSCPKTFAHASQLAAHRSRHINERGHQCGVCGKAFFSKAILRQHQLTHERTAGIVQQPAAEDHTAAAGKTKIRPCTFPGCQHVAATYQTYYTHRLRHEMAHWCDECGRRFARQTELQRHRRIYHTTDHPYRCEPCNKIFLSRQSYREHMDSHANVRRFECEICDKKFVRRRNLINHRMSHTNLRPFKCALCENTFKYKSDYNRHRKEKHSLPERPGAKGEPAIDAGGVDGIVLMMNNSMVEEASLEEEVEERVLVEEDIVLDTTYGEEIVTKYETIETVEESVVIAHVDDFCRVCLLKQPNLTNVVGRIDGVMIPEMLYKLCGTQIDVDDRYPRRICERCLAMVDCAFNFVSEFRQQDERLRSFYWNGPVSKQLQNYQPQGELERNKRMEALLARNPLLHIGGAKEWSTKATCTDAPTVQCVDTGVNTDEVLEFLTMESVKQEGTEEGTSEIELDDLEDDETSQDMPCDSVGARKELVSMRIDLLTSAEDQDHEVVTDEDNKRKQTRRSLRLRKLDNSSEKANDLSEAEEEQWEVGSQSSADGEMLPVYDDRLRCYICDYTARDAELFEQHLETHLPMLPHECPVCKDAGWCLGPLKSLGSLRSHYRSHSFPHGCNVCGKRFSTDAGFLKHRATHHSGELVCEECGRQFHNRKSLVNHVHRHEALRKESYKCEICKKVFGNRPRLVRHLRVHTGEKPYECQFCNRRFNDSHQHQRHERFHRTEKHGYQCESCGQRFDSERKLGTHNMTAHMTAEEQEAYATERRKRYERRMGKLKDSRCPFEGCDYEAKTYGAMYVHKRSKHILRIKCDFCNKHFAFQNQLELHLKLHTGEKPYKCDICDRSFRRPFSYREHMEQHESDKKYECETCGKSFGRPRYLQAHRQTHTTEKPFACATCGNQYKTKGEMKKHSRMKHDIVFLPEKNEQVEEAYIVEYVDPFVVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-