Acou006708.1
Basic Information
- Insect
- Anopheles coustani
- Gene Symbol
- -
- Assembly
- GCA_943734705.2
- Location
- OX030900.2:79497972-79502484[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2 1.6e+02 3.2 1.6 1 23 159 182 159 182 0.93 2 10 0.21 17 6.2 0.2 2 23 194 216 193 216 0.91 3 10 0.02 1.5 9.5 2.1 1 21 938 960 938 962 0.95 4 10 0.15 12 6.7 0.4 2 20 976 995 975 999 0.93 5 10 1.7e-06 0.00014 22.2 2.6 1 23 1035 1057 1035 1057 0.99 6 10 0.00022 0.017 15.6 2.3 2 23 1113 1135 1112 1135 0.93 7 10 0.00061 0.048 14.2 2.3 1 23 1151 1173 1151 1173 0.95 8 10 0.011 0.84 10.3 6.9 1 23 1179 1201 1179 1201 0.98 9 10 0.00095 0.075 13.6 2.5 1 23 1209 1232 1209 1232 0.97 10 10 1.1 89 4.0 0.5 1 23 1241 1263 1241 1263 0.96
Sequence Information
- Coding Sequence
- ATGGATATTTTCCAAAATCAATGCAGCGAAAGCTTGGGCTTTGATTCGATGCTCTCGTCGAATCATCTCAATTCACCGCTGCACGATTCACCGGGTTCGCCAAATCAACTCACATTCGGACCCTCGTCGCCGTACTTTTCctccatctcgcagcaactGTGCGGGACGGGAACTGGCGGCGGGTCCACCAGCGGTCCGAACGATGTGATACTTCCGAGCATTTTCGTGAAAATTCCCACTCAAATCAATCAGCAGTACCAGCAGGAGAACCGGCTGCGCAATGCACGCAATCCAAGTGAGATCAAGTGCGAAGAAAGGGCGGAACCTATCAAAAGTGAGATGGCTGATACACGGTTGAAGCTAACAAGCGCAACCATTTCCGACCAGCTACCCGACCTCATCGATAACTACTTGAACGATACACCGCGTGCATCGAGCAATAATGGGGTGGGTTGTGCTGAAGAATACTCCATCCATCGTTGTGATCACTGTCCGTATGCAACCCTCTCGGAGCCATCGTTGGCtgagcacaaacaaacaaagcataCCACGGGTGGACGAATGCTTCTCGGTACCCTAAGCTGTCCGGTTTGTGAGAATAAGTTTTACAAAAAGACAGTCCTAGAGCTACATTTGCTGGACGACCACGAAATGGCAAGAAACGAGGTGGAGTTGCTGTGCGGTAGGATTTCAAACCTTCAACAGAGCGCAGGTTGTGCTCCATCGGCCGTTTCTTCGTCTGTGGCACAGACCAGCAGCACTCTAACGCAAACGATTTCCACCGCGGTGGCCCCAAACAAGAGTCGGATCTACATTAAAGATGTACAGTTGCTCAAAAAACCGGATGTTATCGCCCAGGAGACGCAAAATGGAACCCATGTTCAGCAAACCCAGGTTCAGCAGATGCTTCCAATGGATCAACAACAGCAATCTTCGCACCCTTGTTCGCAAGACAATCATCTTTCTGCTACAGAATCGTCTTCCCATGAACAGTACCAGAGCGAACAACACCAACCAGCCGCACCAACCGCACATGGTTCCGGGAGCGGTAGTAAAATCTTCATTCGGAATGTTTCTCTGCTGCAGAACGTTAACTTTACACCGACGGCTGAAAATCTGCTTTCCAATGGTGGCAAGTATCATTCGTTTATGAACCATGAGTGTCAAAGCGATCTGTCGTCGCCCGCAATCGATACATCTTCGTCGATCGATGATAGTTACTGCCAAATGATGCCTTCGACCGTCGCTACGCAACCGAGGAGCAACCGTATCTAcattaaaaatgttgataTTCTACGAAATCCTCTGCTTTCATTGGATCACACAGGGCCGGCGTCGGCATCCAATTCGTACAATGCGCCGACCACCAGCCGGGCAAGTAGTTGCGAAAGTATAATCTGCACATcgactccaccaccaccaccaccgccggtgCCGCAGCCATCAACCTCGTCGCAATCACTTCCACCGATAGtgccaccaacagcagcaacgaTAATCCCTCTTTCGCAACTAACCGAATCGCAGTTGGCGCCAGGAAATGAGCAATCTCTTACCGGAGAGGGTATGGACCAAGGCTTGAGGCCTTCAGTGGACGAAAATGGGAGTATGCTAGGACTGATGGCaccacagcagcaacaaacgcAATCGATCGGACAGGGAGCGATCAGTTTACCCATGATGTACACCACCGTATCAGAACCAACGAGAATCCCGGACAGTTGCTCATCGTCGTGTATTTCCATCGCACCGGTAAACTCCTCATCGACAACCAACACCCAATCGAACCCATCTTGTAATGGGTATCAGTTAGCTTCGTTTACTTCCGATGGGCAACACCAACAGCAGGAGCcgaggaaaagtaaaatatttatcaaaaacataagTGTCCTCAAGCAACCGACCATCCACCTGAAATCGGTCGACGAAGTGAACCTGATGACGTACGATCAGCTGCAGCTGCAAAACTTACTTCCCGTCGGAGTGAACGCACCGGTTGGGTGTATCATGAGTATGGATCAGTCGAGCGTTCATCTGGACGGAAGGCGCCAGCAGGACGGCATGATGGACGGTGGTAACAATGCCGAAGCGATAGAACAATCTTTTGGGCAGCTAATGGAAGCGGTTGTCGAACAGCAGCCACACGAGGAGGCCATGGATGGATACCAAGATGTTGGTTGCTACGATGACTTGGATGTTTGCGATTTCAGCAATGGATTTAACGAACGGGACGATCCGGGTGGGGGTGAAGGTGCAATAAGTGTCCCATCGGGGGGTAGCAATAACAACACCCTAAGCATGAGCTGCGATGGATTACTTGGAGAAGCACGTTGCGACAATTTTCAATCCGGGTTCGATCAAGACATTATCCTGCTGCAACCATCAAACTCCAGTGGCGGCGACTCGCAACCAAACGAAACGCAAAAGATGTCCGAAAGTTGGCCACCGGTCGTTGGCGGTGGTTCTTTACTTCCACAGGACACTTCTTGTCCGTCGGAAAGTGTTCCCATGGAGGAAACCGTTAGTGAACCGCATAATGATGAGGTTGAGCAGCAGCAAGATAAAGACATTCTGTTCCTATGTGCCCAGGAAGTGATCAATCTCGACCCTCCGGCTGATGAACCGAAGGTGAGCGAAGTGGACGAAGGTGTCGGCCTAACGGATAACTCGATCGCCGAACTTCCGTCCACTGCAACAAGCGACCAAGCATCGGATCGTCCTCGGCCacgcggtcgtccaaagggcgCAAAGCAGACGGGCATAACGAAGCTGAAGAAGCTATACTCCAATCTTACCCCACAGGAGGAGGGCTACAAATGCGACATCAAAGAGTGTGGGGCACGCTTCCGGCAACCGGATCGGCTCGAGTATCATCGAAAATGTCACTTACCGGCAACAGCGTGCAGTGCCGAGTCGGGCGCAATCCGATGCCCGGAGTGTGGCTCGCTAGAGTTTCGCAACTGGAACACACTCCATACGCACCTGTGGCGTGAGCATGCGGTTGATATGGAACTGTACGCGTGTCAGCTGTGCAGCTTCAAAACGCCAGTCCTTTGCCGTTTGACAAACACGCACATGAAGATTCACTCAGAGGAGCGTAACTTTAAGTGCGCCATCTGCTCGAAGGCGTTCAAGAACAACAAGCAGTTGCGGAATCATCGACGATCGCATCGGGATCCGGTTCAGCCGGTTCAAACGCAGCAACTGCAGCAACAGAACACTTCCGAGGATGTTGCCTCAACCGACATGGCGGTGGTGGAGAATGCACCCCCGGTGGAATCAGCTACAGCCGCCAAGTCGTCGTCGAAGCCAAATAAACCCTCCGCCGTTCCTATTAAGTGTGTCAAGTGTGGTCAAAAGTTCACCAGCCAGCGCCAACTGCATTCCCATATGGAAGCGAAGCATCCACCCACCTCGGACGGAGGGCTGGCGAGTGAGGCGCCCGGGAAGCATCGATGTGTCATGTGCGGGATGATGTTTAAGACGCGCTACCTGCTGCAATCACACTCGGCGAAACACTCGGACGAAAAGCGATTCAAGTGTGAACACTGCGATTACACGACGAACGATCACAATGCCTTCCGGCGTCACAAGATGCGCCACAACACCAAGGGGAACCATATGTACAAGTGTAGCTACTGCGACTACACCAGCATCCAGAGCACGACCTACCGGAAGCACCTGGAGCGGATGCACGCCGACGAGGCATCGCGGTTGCTTTACAAATGCGCCAAATGTCCGTTCGTGTCGATAAGCGAGCTGAAATATCAGCTGCACCGGGCAAAGCACGAACATCCGGAGAATGGTGAAGACAGCCCGATCGAGGACACACAGAAAATCCCCGATGAACAGATGCCTTTGGAGGGAAATGTTTCGATAGTGGAAGATGCAGTCGGTAACAGTCAAGAACAACAGCAAGAGGATGATTCACGTGCCTGCGAGAGTGTCGGTTCGGATGTCATGATCGTGGATAATCGAGAACCGATGGATTTGAACCATTCCAACTACGAACAGCTTCAACTACAACACCCCGACGTAAGTGGCCTTCAGCTCGtacagcaccaacagcagccCATCATTCGACCAGCAATGTTCGCCAACAACTTCTCCAAGGTGGATAACTTCTACGGCCATAGCCAACTGCAACCGAAATTACTGAAGCTTACCGATCGGATTCCATCACATAGGGTGTCCCCGCTTGGGCAGCTTCCGTTGCTACAACCGCTAGGCGTGCAGTCGTCGCTCATTACACTACCGGGGACTGGTACTTCTGTTTCGTTTGCTGTAAGTTCTCAGGATCTAGCAACCACTGACTTTCAGATGAACTCGTATGATatgcagcagcatcaacagcaacagcagcagctggagCAGTacgatcatcatcagcagcaaatGATGGTCAACTCAGTAGGCGACACGATTGTGCTGGGGcgaaattga
- Protein Sequence
- MDIFQNQCSESLGFDSMLSSNHLNSPLHDSPGSPNQLTFGPSSPYFSSISQQLCGTGTGGGSTSGPNDVILPSIFVKIPTQINQQYQQENRLRNARNPSEIKCEERAEPIKSEMADTRLKLTSATISDQLPDLIDNYLNDTPRASSNNGVGCAEEYSIHRCDHCPYATLSEPSLAEHKQTKHTTGGRMLLGTLSCPVCENKFYKKTVLELHLLDDHEMARNEVELLCGRISNLQQSAGCAPSAVSSSVAQTSSTLTQTISTAVAPNKSRIYIKDVQLLKKPDVIAQETQNGTHVQQTQVQQMLPMDQQQQSSHPCSQDNHLSATESSSHEQYQSEQHQPAAPTAHGSGSGSKIFIRNVSLLQNVNFTPTAENLLSNGGKYHSFMNHECQSDLSSPAIDTSSSIDDSYCQMMPSTVATQPRSNRIYIKNVDILRNPLLSLDHTGPASASNSYNAPTTSRASSCESIICTSTPPPPPPPVPQPSTSSQSLPPIVPPTAATIIPLSQLTESQLAPGNEQSLTGEGMDQGLRPSVDENGSMLGLMAPQQQQTQSIGQGAISLPMMYTTVSEPTRIPDSCSSSCISIAPVNSSSTTNTQSNPSCNGYQLASFTSDGQHQQQEPRKSKIFIKNISVLKQPTIHLKSVDEVNLMTYDQLQLQNLLPVGVNAPVGCIMSMDQSSVHLDGRRQQDGMMDGGNNAEAIEQSFGQLMEAVVEQQPHEEAMDGYQDVGCYDDLDVCDFSNGFNERDDPGGGEGAISVPSGGSNNNTLSMSCDGLLGEARCDNFQSGFDQDIILLQPSNSSGGDSQPNETQKMSESWPPVVGGGSLLPQDTSCPSESVPMEETVSEPHNDEVEQQQDKDILFLCAQEVINLDPPADEPKVSEVDEGVGLTDNSIAELPSTATSDQASDRPRPRGRPKGAKQTGITKLKKLYSNLTPQEEGYKCDIKECGARFRQPDRLEYHRKCHLPATACSAESGAIRCPECGSLEFRNWNTLHTHLWREHAVDMELYACQLCSFKTPVLCRLTNTHMKIHSEERNFKCAICSKAFKNNKQLRNHRRSHRDPVQPVQTQQLQQQNTSEDVASTDMAVVENAPPVESATAAKSSSKPNKPSAVPIKCVKCGQKFTSQRQLHSHMEAKHPPTSDGGLASEAPGKHRCVMCGMMFKTRYLLQSHSAKHSDEKRFKCEHCDYTTNDHNAFRRHKMRHNTKGNHMYKCSYCDYTSIQSTTYRKHLERMHADEASRLLYKCAKCPFVSISELKYQLHRAKHEHPENGEDSPIEDTQKIPDEQMPLEGNVSIVEDAVGNSQEQQQEDDSRACESVGSDVMIVDNREPMDLNHSNYEQLQLQHPDVSGLQLVQHQQQPIIRPAMFANNFSKVDNFYGHSQLQPKLLKLTDRIPSHRVSPLGQLPLLQPLGVQSSLITLPGTGTSVSFAVSSQDLATTDFQMNSYDMQQHQQQQQQLEQYDHHQQQMMVNSVGDTIVLGRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00109427; iTF_00107962;
- 90% Identity
- iTF_00109427;
- 80% Identity
- iTF_00109427;