Basic Information

Insect: Anopheles coustani
Gene Symbol: zfh2
Assembly: GCA_943734705.2
Location: OX030902.1:12159233-12164672[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.022 1.7 9.3 0.3 2 23 49 71 48 71 0.92

2 10 0.11 8.7 7.1 0.1 2 23 189 211 188 211 0.94

3 10 1.2 92 3.9 0.2 2 19 301 318 300 321 0.95

4 10 4.1 3.2e+02 2.2 0.6 4 23 339 359 335 359 0.86

5 10 0.0097 0.77 10.4 4.7 1 23 372 394 372 394 0.96

6 10 0.01 0.79 10.4 3.4 2 23 401 423 400 423 0.93

7 10 0.00017 0.014 16.0 0.2 1 23 521 545 521 545 0.91

8 10 0.13 10 6.9 0.6 1 22 617 638 617 641 0.89

9 10 0.00077 0.061 13.9 0.1 1 23 742 766 742 766 0.93

10 10 5.1e-05 0.004 17.6 2.8 1 23 1591 1613 1591 1613 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.022	1.7	9.3	0.3	2	23	49	71	48	71	0.92
2	10	0.11	8.7	7.1	0.1	2	23	189	211	188	211	0.94
3	10	1.2	92	3.9	0.2	2	19	301	318	300	321	0.95
4	10	4.1	3.2e+02	2.2	0.6	4	23	339	359	335	359	0.86
5	10	0.0097	0.77	10.4	4.7	1	23	372	394	372	394	0.96
6	10	0.01	0.79	10.4	3.4	2	23	401	423	400	423	0.93
7	10	0.00017	0.014	16.0	0.2	1	23	521	545	521	545	0.91
8	10	0.13	10	6.9	0.6	1	22	617	638	617	641	0.89
9	10	0.00077	0.061	13.9	0.1	1	23	742	766	742	766	0.93
10	10	5.1e-05	0.004	17.6	2.8	1	23	1591	1613	1591	1613	0.98

Sequence Information

Coding Sequence: ATGAAAGCAGGCCTGGACGCCCAAGATGCAATGGATACGGCGGACAACGGGCTGTGCAGCATACTGCAGGAGAAGAAGATGTGGAACGGCGAGAACGCGGCCAGCAACAACAAGCAGGCGGCGGGCTGCAAGGACCGCTGCCTGGTGTGCAGCGTGTGCAACAAGTTCTCGTCGAAGAAGGCGAACGTGATGCAGCACCTGCTGGCGAGCCACAACCTGGTCGGCAACGAGCTGCTGGGCGGTGCGAGCGAGCTAGCGCCCAATGTGCCATCGCTGCAGAAGAAACCGTTCGACTACTTGCGCACGCTGACCGAGGCTCGGTGCGCCCAGAACCTGCGCCTCATCGAGAAGGTGACGTTCATGAGCGACTCGTTCGCGCTGAAGGAGAACTGCAACGATCTGAAGCACGGCAGTCTGGCGGAGATGCTGGAGCAGTACCAGGCTGCgaccaagcagcagcagcagcagcaacaacaacagggtCATGAACTGAGCGAAGGAGTGACGGCCGCAAAGTCTCCGCCATTGGAGCGACAACCgcagcagctgctgcagcaACATCTGACGTGCCCGCTCTGCTCGGAAACGTTTCTCGATCAGGTGAACGTAGAGACGCACGTGCTGCGCGTGCACAACATCAAGATGGATGGGCTCAATCGACTGCTGAAGCTGGTGGATACCTCGCAATTTCTGAAAaccaccacctcctccacGAACGGCGGCGGGCTGGCCTCGTCCGGCAAGTcgcccagcaacagcagcagtccGATCGAgaagcaccatcatcaccaccaccatcatcaacacCAGCCGCCGTCGCCGGCTGTCTCTCCGGTCGGGTCGGCCGGCAAGGAAGGGTCGGTGTCGccgggcggcggcggcggtggcgtgCCGAACATCCGGTGCGCGCTCTGCAAGGCGTCGTTCGACTCGATGGTCGACCTGAAGATCCACTGCAACGAGAGCAACCACTTCAAGCGGAGCGCCGACTCGGACGATCTCGCCTGCTTCCTGCACGACTGCAAGGACGCGTTCGACAACCTCGCCGACCTGAACCAGCACTTCAAGGCAAGCCATCTCAACTTTCTGATCTCCGAGCATCACACCTACAAGTACCGCTGCCGCCAGTGCCCGTTCGCGTTCAAGACGCACGAGAAGCTGAGCCGGCACCTGTTCTACCACTCGCTGCGCGAGTCGACCAAGTGCTTCTACTGTGATCATCACTTCAAGAACATCAACTCGCTGACGGCGCACATCGCCGAGAAGCACCCGCAGGAGGCGCTGCAGTCGAAACCGTCCCCGCCCGGTATCGCCTCGCCCGACACCTCCATCCTGTTCTTCAAGGACCTCAAGCGCAAGATGCTCCAcagtcagcagcagcagcagcagcagcagcagcaacgcaaTGGGCTGAGTCCGCGGTCGGATCGGTCGGGCGGGCGGGACGCCCGGGATAGTGTGGACGAGGATCGGCTGAGCGAGAAGTCGGTCAGCTCGAAGAGCAGCAGCTTCTACTACGACAAGAGCCTCGACGGGAGCGGCACGCTGGACGGGGGTCGGTATGCGTGCGGCGACTGCCAGTTTTCGTTCACGGATGCGGCCGCCCTCGAGCGCCACCTGGCCACCGCCTGTCATATGCCGCGGGACGACAAGGCATCGCCCGATGGGTCGCTGCTCGGGTCGTTCCCAGCGCTCGGCAAGCAGCAGTCGGGCACCGGCGGcggccaccagcagcagcagcaggcccaCTCGGGCTCGGGGCTGCAAACCCAGCAGCTGCCCGCGTCCGGCTCGGCGTCCATCTTCTACGACATCAAGTCGGAGAAGTTCACCAACCCGAACCGCCCGTTCAAGTGCACCATCTGCATGGAGAGCTTCACGCAGAAGAACATCCTGCTGGTGCACTACAACAGCGTGTCGCATCTGAACAAGCTGAAGAAGCTGAAGGCGGAGAAGGGTTTCGCGCAAATGTTCACCGGTTCGCTGCTGGGGGCCAGCGACAGCGACGGTGGCAGCTTGGAGCGGGGTAAGAACTCACCCTCGCCGTCGAGCCTCGTGCGGGAGGTGGGTGCGTCGGCGTCCCTCGGTGGATCGTTCAGCGACAAGGCGGCCACGCCCTTCTCGATGCCGATGTTCGCCGTCGACGGGTGTCTGGGATCGGGGGCGAGTGGCGGCGAGAAGCGCAAGGACATCAGCGACGAGAAGGAGTCGGCCCGGAAGAAGTTCAAGTGCGACATCTGCAACGTCGCGTACACGCAGGGCAGCACGCTGGACATTCATATGCGCAGTGTGCTGCATCAGACGCGCGCCTGTCGGCTGCAGGAGCGAGGTCTCTTCTCCGGACAGCAATCGAGCAACGCGTCCACGGcgtcccagcagcagcagcagcaaccatcCCCACAGGGAGCCGCCGCCGATGGGCCGAAGAAGAAGGCAGGCAGCGAGTTCCCGCTTATCCATCCGATTCCGGAAAGCCACGATCAGTCGCCGAATCTGCTGGATGAAAACTCCATGCGCAAGCTAAAGTCGCCttccgagcagcagcagcagcaacagcagcaacagcagcttcagcaacagcagcagcaactacAAGCGATGGGGCAGCTCGGAGCGGGACCGCTGTTCTGCGGAGTGCCGGCCGTCGGTGGAGGAGACAAGCCGGAGATCTGTGTGTGCGAGTGCTGCTACCAGATGTTCCCCGGCAAGCTGATGCTCGAGGCGCATCTCGACCTCAACCCGGAGTGTTTGGCGCACAAGAAGAAGCTTCTGgatgcggcggcggcggccgcggCCGTCCAGGACAGTGCCGCTGCAGCCGCCTCCTTCAACGACGGTGCAGCtgcggcagcggcagcggcggcggccgccgcCTACCAACACCAGGCGCTCATGAACGACCTGGTGAAGGTGAACGCACTGTCCGGGTTCGACGCGCTGAACGCGTCCGACGCGCTGCTGGGTGCGAAGAGTCCGCTCATGCCGGCCCTCGATCCCACCGCCAACCTGATGGATCCGAACTTCCTGAAGAACGCGTCGCTGCTGCAGTTCGCCGCCTCCGATCCGAACGCCAAGCTCAACCCGAACGCGCTGAACGTGCTCAACTTCATGCACTTCCACCATCTGATGTCGCTGAGCTACCTCAATCTGGCGCCGCAGCTCAACTTTGGCGGTGTGCCGGCGGGCAAGGTGGACGGTTCCGGCGGTGGTAAGCCGGACGGTTCGCCGGGCGTGGGCATTTCCGACGGGGGCGTCGGCAGCCTGGGCGCGAACAGTGTCGGAGTGGGCGGCGGGAAGGCGGGCAAGCACGGTCCACCGCCGGGCGTCTGTGCACCGGTCAATCTGAACGGCAAGCCGCTCGACCTGAACAACCTGCTGCCGCACGGGCTGGACCCGAAGATGGGACCACAGCCGCCGCAGCAGGGTGGCCAGCAGCCGTGCACGCAGAAGCGGGCCCGCACGCGCATCACCGACGAGCAGCTGCGCATCCTCCGGTCGCACTTCGACATCAACAACTCGCCGAGCGAGGAAAGCATCCAGGAGATGTCGATCAAGGCGAACCTGCCGCAGAAGGTGGTGAAGCACTGGTTCCGCAACACGCTGTTCAAGGAGCGCCAGCGCAACAAGGACAGCCCGTACAACTTCAGCATCCCACCGTCGACCAAGCTGAACGTCGAGGAGTACGAACGTACCGGCGAGACGAAGGTAACCGACCTCGAGACGTCGTTCAAGTCGGTCGAGACGTCGCAGGACAACTCCTGCTCGCAGAACTCGAGCGACATGAGCAAGGCGCTGAACGAGGCGATGAAGCAGAACATCTCCAAGTCGCTGCTGGAGTCGCTCAGCAAGCACCAGCAGTCGGCGGCCGGCCACCCGGATCTGGTCGGCGCCGCCTTCCAGCTCAACAAGAGCCTCTTCCCGGACAGCTTCGTCGGCGCGGACTTCAGCAGCCACGACGCGGTCAGCTCCGTGTCGGACTACTTTCAGCGTGCGGCGGCCGATGCGGTGGCACTCGGGGCGGCCGTCGGTGCGGTCACGATGCCCGGTGCGGGCGGTGGAGCCGGTGGTGTCTTGAGCAGTGTCGGTATCGGTGGGCCTGCTCCTGGTGGTGGAGTTGGTGGTGGGGGTAATGTTGGCACTGGCCCACTtaccggcggtggcggcggcggcggtggaggtggcgggggtaagaagaaaaagatcaagtCCGAGTCGTCGAACGATAGTCCAACGCCGGCGGACTTGCAGCTCGACTCGTCGAACTCCAGCCCGATGCCGATGCGACCTCCGAGCGCCATCTCACTGAAGAAGCACATGGCCACACCGCCGACGGCTGGCAGTACTCCCGGGAGCGGTGGTGCTGCCGGTGGTGGCGGAGGCACTGgtgctggcggtggtggtggcggcggtggcacGCTGCTCGAAGACATGAAGATACCGAGCCCGATCGACAGTCCCGTCATCTCGTCGCCCAACTCGATGGGGCTGCACACGATGCCGCCGCAGACGCAGCCAATCACCTGCTCGAACGGCAAGCGGGCGAACCGGACGCGCTTCACCGACTACCAGATCAAGGTGCTGCAGGAGTTCTTCGAGAATAACTCCTACCCAAAGGACAGCGATCTGGAGTACTTGAGCAAGCTGCTGATGCTTTCACCCCGCGTGATAGTGGTGTGGTTCCAGAATGCTCGCCAGAAGCAGCGCAAGATTTACGAGAACCAGCCCAACCCGACGTTCGAGACGGACGAGAAGAAGGCAATCAACATCAACTACACCTGCAAGAAGTGCAACCTCGTGTTCCAGCGCTACTACGAGCTGATCCGTCACCAGAAGAACCACTGCTTCAAGGAGGAGAGCAACAAGCGGTCGGCGAAGGCGCAGCTGGCCGCGGCCCAGATCGCCCACTCGTTCACCAGCGGCAGCGAGGACTCGGACTCCAGCCTGGACGTCAGCCGACGCGAGTTCCAGCCCCGCGAGAACGACTGCCCCTTCTAG
Protein Sequence: MKAGLDAQDAMDTADNGLCSILQEKKMWNGENAASNNKQAAGCKDRCLVCSVCNKFSSKKANVMQHLLASHNLVGNELLGGASELAPNVPSLQKKPFDYLRTLTEARCAQNLRLIEKVTFMSDSFALKENCNDLKHGSLAEMLEQYQAATKQQQQQQQQQGHELSEGVTAAKSPPLERQPQQLLQQHLTCPLCSETFLDQVNVETHVLRVHNIKMDGLNRLLKLVDTSQFLKTTTSSTNGGGLASSGKSPSNSSSPIEKHHHHHHHHQHQPPSPAVSPVGSAGKEGSVSPGGGGGGVPNIRCALCKASFDSMVDLKIHCNESNHFKRSADSDDLACFLHDCKDAFDNLADLNQHFKASHLNFLISEHHTYKYRCRQCPFAFKTHEKLSRHLFYHSLRESTKCFYCDHHFKNINSLTAHIAEKHPQEALQSKPSPPGIASPDTSILFFKDLKRKMLHSQQQQQQQQQQRNGLSPRSDRSGGRDARDSVDEDRLSEKSVSSKSSSFYYDKSLDGSGTLDGGRYACGDCQFSFTDAAALERHLATACHMPRDDKASPDGSLLGSFPALGKQQSGTGGGHQQQQQAHSGSGLQTQQLPASGSASIFYDIKSEKFTNPNRPFKCTICMESFTQKNILLVHYNSVSHLNKLKKLKAEKGFAQMFTGSLLGASDSDGGSLERGKNSPSPSSLVREVGASASLGGSFSDKAATPFSMPMFAVDGCLGSGASGGEKRKDISDEKESARKKFKCDICNVAYTQGSTLDIHMRSVLHQTRACRLQERGLFSGQQSSNASTASQQQQQQPSPQGAAADGPKKKAGSEFPLIHPIPESHDQSPNLLDENSMRKLKSPSEQQQQQQQQQQLQQQQQQLQAMGQLGAGPLFCGVPAVGGGDKPEICVCECCYQMFPGKLMLEAHLDLNPECLAHKKKLLDAAAAAAAVQDSAAAAASFNDGAAAAAAAAAAAAYQHQALMNDLVKVNALSGFDALNASDALLGAKSPLMPALDPTANLMDPNFLKNASLLQFAASDPNAKLNPNALNVLNFMHFHHLMSLSYLNLAPQLNFGGVPAGKVDGSGGGKPDGSPGVGISDGGVGSLGANSVGVGGGKAGKHGPPPGVCAPVNLNGKPLDLNNLLPHGLDPKMGPQPPQQGGQQPCTQKRARTRITDEQLRILRSHFDINNSPSEESIQEMSIKANLPQKVVKHWFRNTLFKERQRNKDSPYNFSIPPSTKLNVEEYERTGETKVTDLETSFKSVETSQDNSCSQNSSDMSKALNEAMKQNISKSLLESLSKHQQSAAGHPDLVGAAFQLNKSLFPDSFVGADFSSHDAVSSVSDYFQRAAADAVALGAAVGAVTMPGAGGGAGGVLSSVGIGGPAPGGGVGGGGNVGTGPLTGGGGGGGGGGGGKKKKIKSESSNDSPTPADLQLDSSNSSPMPMRPPSAISLKKHMATPPTAGSTPGSGGAAGGGGGTGAGGGGGGGGTLLEDMKIPSPIDSPVISSPNSMGLHTMPPQTQPITCSNGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLMLSPRVIVVWFQNARQKQRKIYENQPNPTFETDEKKAININYTCKKCNLVFQRYYELIRHQKNHCFKEESNKRSAKAQLAAAQIAHSFTSGSEDSDSSLDVSRREFQPRENDCPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109418;
90% Identity: iTF_00109418;
80% Identity: iTF_00109418;