Acou016402.1
Basic Information
- Insect
- Anopheles coustani
- Gene Symbol
- -
- Assembly
- GCA_943734705.2
- Location
- OX030902.1:12554860-12557199[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00057 0.045 14.3 1.5 6 23 246 263 246 263 0.99 2 13 0.079 6.2 7.6 4.2 1 23 269 292 269 292 0.93 3 13 0.0024 0.19 12.4 0.1 1 23 300 322 300 322 0.93 4 13 0.11 8.4 7.2 1.9 2 23 331 352 330 353 0.93 5 13 1.1 84 4.0 0.1 2 23 406 428 405 428 0.90 6 13 5.3 4.2e+02 1.8 0.0 6 23 438 455 438 455 0.96 7 13 0.00017 0.014 15.9 1.2 1 20 461 480 461 484 0.94 8 13 0.001 0.078 13.6 3.4 1 23 492 514 492 520 0.96 9 13 0.0016 0.12 13.0 1.4 3 23 524 545 523 545 0.97 10 13 0.01 0.79 10.4 0.1 2 20 552 570 551 573 0.89 11 13 0.00015 0.012 16.1 1.4 2 23 613 634 612 635 0.94 12 13 0.0074 0.58 10.8 1.8 1 23 641 663 641 663 0.95 13 13 0.016 1.3 9.7 1.5 1 23 669 692 669 692 0.91
Sequence Information
- Coding Sequence
- ATGTTTGACCTTCTAGATGAGTCAACGCgattaaaacaatgtttgctTTGCCAGTTGGAATGTTCGAATCGATTGCTGGTAAGCCAGACAGCAGGGTCGGGATTCGTGGTCTTCGATGTCATTCGCAAACATTTTTGGTTTACAGACACTTACTACGATGGTCGGTGCATTTGCATTCCCTGCTGGCGAGCAACGGAATCGTTTCATATGTTTTATAAAGAAATCGAACTGGCGCATTCCGTGAAGCTAGAAGCAGTCAAACAAGAAGATTCGTTACAAACAAACGATCCTAACCATTTGACTGACTTAGACCCGCCAGACTGGGAGTGTGGAACCTTGGAAAAATTGAACGAGGTGTTCGTGAAAGAAAACCATTCGGAAAGTGACAACCAGCAGGATACGCTCAGCGATAGCCCAGGACTATCCGCATCCGAAGAAGAATCGGAATCGGAATCTACGCTTTCGCTAGCCAAACGGACAAGATCAAACAGGACTGCGGTCGCGAAACGCACAACACGATCTACCGGAAGCGAGGAAATGAAAACTTGGCTACCGGGCGAAGGCTTGACATTATGCCGGTGCATACAGGGGGTTCTCGAGGCGCAGTGTCATGTGTGTGTCCGAAATAAAGATAGTACGGCAAAACCGAAAGCTGCTGAGCAGCCGTACATGCGGTTTGCCAAACTGATGCGACACTTTCGAGAAGCGCACGGCACGCCCGGGTACGCCGTGTGCTGCAACCGAAAGTATGCCCGAAGAAGATCGCTTAGGGCGCATATGCGAACGCACGGCAAGGTTACAGTGTACCACTGCCATCGGTGTCGTATAAAATTCCGCAAGGAGGAATCCTTAAACGAACATAACAACCTCGTACATCTCGACGACTCGGAGAAGCAGTTTCGGTGTGAGAAGTGTAGCAAAGGATTCGCGACCGAGATACTGCTCGCTTCGCACGAGGACTGGCACAAAAACGTGGAGCAAAGGAACATCGTTTGTAGTGATTGTAACACATTcTTCCCTAGCATTGTAGCAATGCATAAACATAAATCTTTGCATCATCCAACGGTAGAAAACGCTGATACTGCACAAAGTACGAACACCACAGGGACGGAAAATCAGATGGAAGAGCTCTTGATAACAACAGAATACCGGATGCGTCTTACGGCCGAAGAAATGGCCAAGCAAAACGAACTTATCGAGCGCTACTGCACGCTGTACTGTGACGTTTGCCAGTTCGTCGCATCTGGGTTCGCTGATTTGAAGCAGCACGTATCCGAAGAGCACGGTTTGCGCTCGGTCAAGGTGGTTTGCTGCGATCAGCCGTACACAAACCGGGTGCGGTTGTACGAGCACGCCCAGTTACACGAGGATCCTGATCGCTTCCGGTGCAAGGTGTGCAGCAAGCGGTACGTCAACAGTCGCAGCCTGCAGAATCATCAGTGGCGCATTCATACACCGGCCGCCGAGCGACCCTTCTGCTGTGACGTTTGCGGAGAAACGTTTGTCAAGGACTATCTATTGAAGAAGCATCTCTCCTTTCATCTGGCAAAGCACCAAAAGCTGAATTTCTGCGAGGAGTGCAACCGATCGTTTGCGACACCGGCCGCATTACGCTGCCATCGGCAAACGTATCACGGGGAAGTGGCCAACTGGATATGTGAGATCTGTGCGAAAGGTTTCGATAGTCGTTCGATGCTAGATAAGCATGTTCCGACGCACAGtgccgaaggaaaaacggaactTAAGCACCAGTGTGAACGGTGCAAACGATGGTTGCGAAACAAAAAGTCCTACCAACAACATCGAGTACGGTGCCACATGAACGCCGGTCCGGTGAAATGTCCATTCTGTGGCAAAGAGTCGAAGAACTCGGTCGCGCTGCGGGCCCACATTCATCTGCACCACGCGGATCGCCCGGAGCATGCCTGCTCGTTCTGCGAGAAGCGCTTCAAAACGGCTCTACGACTGCGTGAACACGAGGCCACTCACACTGGGACCGTGCTCTATAAGTGCCCCTGGTGCCCGCGGACATTCGCCTGCGGCTCAAACATGTACAAGCACAAAAAAGCCGGCCACCCGGAGGAGTGGGCCGCCGGTGTACAGAAGCGCTTTGGCGAGCGATAA
- Protein Sequence
- MFDLLDESTRLKQCLLCQLECSNRLLVSQTAGSGFVVFDVIRKHFWFTDTYYDGRCICIPCWRATESFHMFYKEIELAHSVKLEAVKQEDSLQTNDPNHLTDLDPPDWECGTLEKLNEVFVKENHSESDNQQDTLSDSPGLSASEEESESESTLSLAKRTRSNRTAVAKRTTRSTGSEEMKTWLPGEGLTLCRCIQGVLEAQCHVCVRNKDSTAKPKAAEQPYMRFAKLMRHFREAHGTPGYAVCCNRKYARRRSLRAHMRTHGKVTVYHCHRCRIKFRKEESLNEHNNLVHLDDSEKQFRCEKCSKGFATEILLASHEDWHKNVEQRNIVCSDCNTFFPSIVAMHKHKSLHHPTVENADTAQSTNTTGTENQMEELLITTEYRMRLTAEEMAKQNELIERYCTLYCDVCQFVASGFADLKQHVSEEHGLRSVKVVCCDQPYTNRVRLYEHAQLHEDPDRFRCKVCSKRYVNSRSLQNHQWRIHTPAAERPFCCDVCGETFVKDYLLKKHLSFHLAKHQKLNFCEECNRSFATPAALRCHRQTYHGEVANWICEICAKGFDSRSMLDKHVPTHSAEGKTELKHQCERCKRWLRNKKSYQQHRVRCHMNAGPVKCPFCGKESKNSVALRAHIHLHHADRPEHACSFCEKRFKTALRLREHEATHTGTVLYKCPWCPRTFACGSNMYKHKKAGHPEEWAAGVQKRFGER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00109403; iTF_00107934;
- 90% Identity
- iTF_00109403; iTF_00107934;
- 80% Identity
- iTF_00109403;