Acou011725.1
Basic Information
- Insect
- Anopheles coustani
- Gene Symbol
- -
- Assembly
- GCA_943734705.2
- Location
- OX030901.1:47144540-47147330[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 2.5 2e+02 2.9 1.0 1 23 349 374 349 374 0.81 2 13 0.00031 0.024 15.2 0.6 2 23 381 402 380 402 0.97 3 13 0.024 1.9 9.2 5.0 2 21 409 428 408 430 0.94 4 13 4.4 3.5e+02 2.1 0.7 1 23 440 462 440 462 0.77 5 13 0.23 18 6.1 0.1 3 23 487 514 485 514 0.78 6 13 0.71 56 4.6 0.4 2 23 521 542 520 542 0.90 7 13 1.9e-05 0.0015 19.0 0.8 1 23 580 603 580 603 0.95 8 13 0.0026 0.2 12.3 0.2 2 23 609 630 608 630 0.93 9 13 0.00066 0.052 14.1 0.8 1 23 637 660 637 660 0.93 10 13 3.8 3e+02 2.3 2.1 2 23 668 687 667 687 0.76 11 13 0.00014 0.011 16.2 1.0 2 20 694 712 693 714 0.93 12 13 3.4e-05 0.0027 18.2 0.6 1 23 725 747 725 747 0.99 13 13 0.00025 0.02 15.4 1.8 1 23 753 776 753 776 0.98
Sequence Information
- Coding Sequence
- ATGGCTCAGACTAAAAATTGTGTACTTTGTTTGTGCTACgaacaaaaatgtttgctaGACGTGTGCtgtgaaaataatgaaacgCCGAACAAAACTCGCATCATAACAAAACACCTGGGGTTTGATCTCAAAATAACGCCACAAGCGCAGGTATGCGTGGAATGCTGGAAAAGTGTGTACGACTTTCATCTGTTCTACTGCAAGGTACAAACCATACACAATGAGGAATACACCGAATTGGATCCAGCTGGAAAGATAGCAGATGCTAATGCCAAGGACGAACTGGGATGCGAAGTAGAGTCCTTTTTGGGAGGTACAGTAAAGGCTGAGCCGTTGGAGGTGCATCATGACAGGGATGACACGGAAACGGAATATATCGGCAGCAGCTACACCCAGCCTAGCGGTATCGAAGATGATGCTAGCAATCGACCCAGGCGCCGAGTAAAGCCTCCGGAAAGGTTTAAACCGGACCCGAGTGACATGATGCGGTATGAAGGTAAACTACCGTTCGTGGAAGTGGATGTCATCGCtaccgacgatgacgacggggACCAGGCGTCCGTCGGAACGAATTATCTCGACGGTGCGCAATCAAACACCGATACCGAAGCGGTCGTGGTTGTGCCACCGAAAAAGAGGCGGGGGCGGCCACCGAAGAATCAAAAGACTGTCGTCcaggaagaaaaaccacccaaaaaaaatgtaaccaGGGGTAGGCCACCGAATGCTACCGATGAGCCTCCTAAGAAAAGAAGGGGACGTCCGCCGAAAAATACACCGCTCGAGAGTGAGACCCCAGCAAAGGTGCCGAAAGCGAAAGCAACCAAAACAAGAACCCGAAAAAGTATTAACGATTTGAGCACCGACTCCGAGCAGGATGTACATTCCGATTTTGAATCTTCCGTAAGCCTGTGGCAGTGGAAGGCAATGGGTGGTAAGGAAGAAGACTTCAAAGGGAAGATGGAATCATCCAGTAATTCAGGCAAAAAACGGGTCTTCGGACCAGGCGGTCGAGACCTCAGACTGTTTGCGTACATCGATGAGTTTGTCTGCGAGTACTGTCCCGAGAAGGTCCAGTTCGATCGGTTCATCCATGCGACCCGACACTACAGGGATGTTCACATGGAACGAGCCTATTTAAAGTGTCCCAAGTGCGACAAAAAGACCTACACGTCGGGAGAATTTGTGACCCACGTGGAAACTCACAATGATCCGGATAGATGCAAATGCACAATCTGCGGTAAGATGACGCTATCAAAGGTGGCTCTGAAGAAACACATGCGCTGCCATCAGCTGGATTTGGAGGAGAACAATCCGTTCCCGTGCAGGCTGTGCTCCCGGCGGTTCGAGGCGGAATATAAGCGGGACAAACACGAACTGCTGCACCGACCGAAACCGATCATCCCCAAGCAATACGGTCGTGACGAAGCCATGCTAGAGTTCTACCAGCGCATCTACTGTGACCTGTGCGAAGAGGTGAAACCGGACTCGACATCGTTCGACAACTTCTGGGATCTGAAGGTGCATATGAACAAGCAGCACGAAAAGGCACCGTATCTCAAGTGTCCAATTTGTTCCAAAAAAATGGGCGTGCGGCATCAGATAATGATGCACATTGACGTGCACAAGAATCCGGAACTTTATAGGTGTGAAGTTTGCAACGAGATTCATCAGTACCTCGATCGCCACATGATCTCAGCCCATACGCCATCAACGGCGGCACCGGAAAAGAAACGCTACAACTGTGAGCAGTGTGGAAAAGTATTTAAATTCCGCTGGAAACTGAAGTATCACATCAACGAAGCGCATGGTGTGAAGGATGTGTCCTGTGACATTTGCAAGAAATTCTTCACCCGCCCGGCGCTTGCCGCACACAAACGAAAGGCACACATCGAAGGCGAAGCCTCCTTCCTGTGCGATCATTGCCCAAAATTGTTCAACAAACAGCAAACCCTCCGGATGCACATAGCCGTTGCGCACGAGAACCGCCGAAAGCACAAGAAGTGTAACCTGTGCGGCAAGGAAGTCACCGGCATGACGAAGCACATGCAGATGGTGCACCCGTCGGAAGGCCCGGTAAGCTGCGACCTGTGCGGTAAGAACTTCCGCTCACCATTCCACATGAAGCGCCACCGGCTGAACACATGCGAGGTCACCATGAACGATCGGCCATACAAGTGTGAGGTGTGCGGGAAGGGATTCTCGCTCAAGCTGACGATGACCGAGCACATGACGACGCATACGCGCACCAACCTCTACCAGTGTGCGTTCTGTCTGAAGACGTACGGCTACCTGTCGAACCTGCAGAAACATCGTAAGAAGGCCCACCCGCAAGAGTGGCGCGAGGTGAAAGGGGACCAAAGTATTGTCACCGTCATCCCGCTCAGCGCTCCCGTTGTCGCGCCGGTCACGGAGTACGAAATTCCGATAGCAGGACAGTGA
- Protein Sequence
- MAQTKNCVLCLCYEQKCLLDVCCENNETPNKTRIITKHLGFDLKITPQAQVCVECWKSVYDFHLFYCKVQTIHNEEYTELDPAGKIADANAKDELGCEVESFLGGTVKAEPLEVHHDRDDTETEYIGSSYTQPSGIEDDASNRPRRRVKPPERFKPDPSDMMRYEGKLPFVEVDVIATDDDDGDQASVGTNYLDGAQSNTDTEAVVVVPPKKRRGRPPKNQKTVVQEEKPPKKNVTRGRPPNATDEPPKKRRGRPPKNTPLESETPAKVPKAKATKTRTRKSINDLSTDSEQDVHSDFESSVSLWQWKAMGGKEEDFKGKMESSSNSGKKRVFGPGGRDLRLFAYIDEFVCEYCPEKVQFDRFIHATRHYRDVHMERAYLKCPKCDKKTYTSGEFVTHVETHNDPDRCKCTICGKMTLSKVALKKHMRCHQLDLEENNPFPCRLCSRRFEAEYKRDKHELLHRPKPIIPKQYGRDEAMLEFYQRIYCDLCEEVKPDSTSFDNFWDLKVHMNKQHEKAPYLKCPICSKKMGVRHQIMMHIDVHKNPELYRCEVCNEIHQYLDRHMISAHTPSTAAPEKKRYNCEQCGKVFKFRWKLKYHINEAHGVKDVSCDICKKFFTRPALAAHKRKAHIEGEASFLCDHCPKLFNKQQTLRMHIAVAHENRRKHKKCNLCGKEVTGMTKHMQMVHPSEGPVSCDLCGKNFRSPFHMKRHRLNTCEVTMNDRPYKCEVCGKGFSLKLTMTEHMTTHTRTNLYQCAFCLKTYGYLSNLQKHRKKAHPQEWREVKGDQSIVTVIPLSAPVVAPVTEYEIPIAGQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00109392; iTF_00107935;
- 90% Identity
- iTF_00109392; iTF_00107935;
- 80% Identity
- iTF_00109392;