Acou004685.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles coustani
Gene Symbol
-
Assembly
GCA_943734705.2
Location
OX030900.2:52544258-52553045[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00095 0.075 13.6 1.7 1 23 361 383 361 383 0.97
2 15 6.3 4.9e+02 1.6 0.1 2 8 386 392 386 409 0.83
3 15 0.0001 0.0082 16.6 2.4 1 23 414 436 414 436 0.95
4 15 0.00055 0.043 14.4 4.7 1 23 454 478 454 478 0.90
5 15 0.0029 0.23 12.1 1.4 2 23 484 506 483 506 0.94
6 15 0.0043 0.34 11.6 2.9 1 23 534 557 534 557 0.96
7 15 0.015 1.1 9.9 3.2 1 20 575 594 575 597 0.94
8 15 0.0014 0.11 13.1 3.6 1 23 603 628 603 629 0.96
9 15 0.24 19 6.1 0.6 2 23 911 933 910 933 0.94
10 15 0.012 0.91 10.2 0.2 2 23 951 974 950 974 0.90
11 15 0.52 41 5.0 0.6 3 23 981 1002 979 1002 0.95
12 15 0.004 0.32 11.7 0.4 1 23 1008 1030 1008 1030 0.97
13 15 0.13 11 6.9 0.2 3 23 1040 1061 1038 1061 0.95
14 15 0.016 1.3 9.7 3.7 1 20 1067 1086 1067 1089 0.95
15 15 8.3e-05 0.0065 17.0 0.1 1 23 1095 1120 1095 1120 0.97

Sequence Information

Coding Sequence
ATGGAAGTGAAAATGCAGCACCGATCACGGGCGCATATGTTCCAGATACAAGTCAGAGCACTGATCAAAACACTCAAATGTCTCCAGTCGGACGATAAATACCAGGCCCTGCTGTTTCTTATCTCGGCAATCAAGCTGTACGTCAAGTTTCTGTACAACGATTGCCAGGAACGCCTATATAAGCCCGCAATACTCAAAGAGTTGAACAACATCGAGAATGTGATCGTAGTGAATCTGCTCAAGACGCGTGGTGCGGGTACTGCGTCTGCATCGGCGTCATCAGTGGCAACCGCACGCACGAGTGCATCTTCCTACGGTGGTGGGTTGGCCAGCACAACCCGTCTCGACCTCGGCGGCACGAGCATACGAAGTACGGACCTATCGCTTGGTGGCGATGGGTTGCTGATGATGCATCCACATCGCACCCAACCGCACCCGCCGCTCATGCCCTGGGACTTACGGGGGAAGCTATTGCGCGGTAATCTATTCGACGGCCTGCCCCCGACCGACAGCGTCCGCTTAGGGGCAAATATCAGTGCGGCCGCCTGCAGTTCCCTGTTGAAAGGAGGCCAACGTCTCGCGAGTGCTGGCCGGTGGTTGGGCAACGTCCGGATGACACGCGCACTGGTGCGAATGATCGCGAACCATGATTTCAAGCTGCTATTTAACATGTTCGAGCAGAGTATATTTCCGACGTGGAAAATCTACAAAAACGAGCGAATATTCGTGCGAAAACGGCCCGCCCTAACGACGGTTACCGTCCGAACGTCTCTGCCAGCCATCTGCTACGGCAGCGGCTCGTCGCACTCGCCACCCGCAACCTACATCAAGAAGGAGGAGTTTGATTTCGATCCACCGTATTCGATCGCAGACGATCACTGCTTCGAGGAAATTAAAGATGAAGATGACGACGACCTGCTGCTGATGAAGGAGGACGATTCGATCGACATTTCGAACGAAATCTTCTCGGAAGAGGAATCGTCCACCAATAACACCTCGCTGATGCTTTCGTCCGACACAAACACGCTGGACACGAACGACTCAAGCATGGTTTCGCATGAAAGAAACAAGGAACAGATCTACCAGTGCTTACTTTGTGATAAAAGCtataggaaaagaaaatctctcGTCATCCACTTTAATCTCCATCCGGGATACTGTCCCGATTGTGGGAAGCAACGTGGGGTAACATCGGATGAAATCGTTGAACATAATCGAATCTATCACAAAAATCGACCTCACATCTGTGAACACTGTGGCGAAACGTTCACCCGCAACCAGCAGTATCAGATACACGTCCAGGGGCATTTTATTAGCCAAAAGCGGGTCGCGGAACAAAACTGTAAAAAAATCCACAAACACTGCTGTAAAACATGCGGCATCGTTTTTAACAATCAGAAATATCTCGAAAAGCACATCCAGAAAACGAACCATCAGATGGAAGGCGTGGTGTGCGAAATCTGCGGTGCAATATTCTGTAATAGTATGAAACTGAACCATCACGTAACTCGAATGCATAACAATGTGTTCTCACAAAAGGCATCCTTAGAAAGGAACATGCTGCTACAGCAGACGAGTACCAGCGTTGTGGAAAAATCCTACTGTTGCGATCACTGCGGGTTGTCGTTTCTATCGCAAACAACCCTTCGGGATCACATAAAGCTTGCTCATACATCGGTTCCGGAAGATGTGAAGTCATCACAAACGGCGACGGAGAATAAGTTCGAGTGTAACATCTGCAATAAACTGTTCGCCGCCAAGCGGTCGCTCAAACGCCATAAACTTTGCCATTCGGAAGAGAGGGCCTTCCGCTGCACGGTGGACAACTGCAAAGATGCATACAAAAATCAATCGCACCTAGCGCGTCACATGAAAACCGTGCACCACATCGAGCCCCAGAAGCGACTGCCGAAAGGGAAGGCCGCCGCCGCAaccgctgctgctggtggtggtgcaggtgGCTCTTCTGGCGGTACCAGCGCCACGCtgtccacctccaccaccggcGATCCGTCACGGGCGTCCTCAGCCAGTGCCGACTTCATTAGCCACGGTATTGGCGACGGAGTGACGATCGGTGGTGGTTCATGCGATTCGTTAAaggtcggtggtggtggcgttggCGCGTTGAAAAAGTCGGCCCTCGGTAGCAGCGAAAAATCGCTCGGCGACAGCAGTACCAACTTCAGCGACAATATGTCTTCGTTTAATTACGAATTTTCTGACACGACGGGTGGTGGCAGTTCGACACCGGCCCTTCCATCGCTTGGCGGACGGGACGAAGGTACACCAACGCTACTATCGTCCGCGATGCTCGGCGGAAGTGGTTCAACGATGGCTCCAAGATCCCAAGCGGGTGCATTCAATGATCCTGGAATAAGTTTTGCATCGACAAGTAAGCAACAGCAACACAACCAgctgcaacaacagcaccTTAGCTGGCAAAACCTGGAGTTTGGCTCGGTTCCGCAGCATCGGTCTACAACACTGGCAGGTGGTGGTGGACCTCCAACTCAGCCCATGCAAGACCCATTGGCCACACAAGGCAGCTTTCTGGACACCGGGCATCCGCAACACCACAATCTCCACCACCAAGCGCACCACCCATTAGGACCGGGATCGATGGGTGATCCGAtgggtggtgctggtgctggtggaggGGTTTTTATGGCCTCCTCCAATATGATGCCAGGTGGTGCGAGACGTTTCCCTCTTCCAGATACCACTCTGACCTGCGAGCACTGCGACGAAACGAACTTTGTTAATGCGCAACAGTTTCAGGTGCACGTTCAGGATCATTTTGTCGTGAAGGAGGGCAAGGAACCCGCGGGCAAAAAACTGCTCCGATTGATATGCAAAACATGTAACCTGGTGTTCGCCACTGGCGCCCAGCTCGATCGACACATCCAGAAGACGAACCATCACACGGAGAGCATCGCGTGCGAGATCTGTAGTGCAATATTCAACTCCAACCTCAAGGTCTATCAGCACATGCTAAAGTGCCACAAAAACGaCATTTGGTTTGCGTGCGAGCAGTGCTCGAAAGTTTTCATATTGAAGCAGGACTACGATAAACATCAGCTGGTGCACCAGACAGTCACGGACCGATCGATCATCTGCGAGCATTGCGCATCGTCCTTCCTCACGCAGGAAGCCCTCAAAGAACATATCAAAATAGCGCACTCAATGGACAAAAAATACAAGTGCACCATCTGTAACAAACTGTTCGCCGCTCGGCGGTCGCTCAAGCGCCACAAACTTTGCCACGAGGAGGAGGCCGCCTTCCGGTGTCCGATCGATGGATGCACCGAAGCATTCCGTACGGCGGCGAACTTAGCGAAGCATAAAAAAATGGCTCACCCGGCAGGTATAGTGGCAGCCCCGACATCCCAGGTTCCCGGATCTATCGTTCCCGGAGTGATGGTAGCACACGATTCGATGGGTGAATCACCCCACGTCGCTACCAAACTGCCAGGTACGATGGCCGGTGGTCCGCTCCCAGCCACGGCATCTGGAACCATGAAggtattggagaaggtacaCCAGGAACCGGCTGTGCAAAACGCCGGCGTAGGCCAGGTCATGGCAGGTCATCATGGTACGAACCCGCTCATGGCTGTTGCTGCGGGAATGCTAAAAACCGAACCCCGTCCATCGCCTAGTATGGGTATGGTGGTGCCCCCCTCGAGGACGAGCAGTGCAGGAAGTAGCGTCGGGTTGGGCGGCAATAACACAAACAGTGGCAGCGGGGCGAATTTGCCCTACAATCCATACGAGGCGCAAGGTGCCATGCACTACAACAGTGTTGGACTCGGAGTTTCACCGGGATCGAATATAGGTCCCGCTGGGCATGGTCATCATGCGGCCCtacatcaccatcaccatcatttgcaacaacaacaacagcaacagcagcatggAGGAAATCAACATCATTCATCACAGCAGGCCCTTCCGCATCATCACTCGCAATCTCAGTTCGTTGGCATGACGAATCCAGCCGGTGCGGCCGGCCTGCACTACACGTCGGCACACGGTGGCTCCCGGGGTGGTACGGGTGGCACCTCGGGTAATCtcgaacaacagcaacagcccTCAACGGTTGGCTATCGAATGGCCGGCGAAGGCGGTGCGAGTGTTGGACCCTCTGGTGGCAATACTGGAAACATTCCTTACGGTTACGCTCAAATGGGTAATGCGTACGATTGGCAAAACATGGCTGAAATGGGCAACCAGAACGCAGGTGTGGAGACCGGTGGAATTGTTGGTGGTGCGAATGCCGGACAAACGCAAGTTTCTTCTGCATCCGCCAGCGCAATGAAGGGTGCTGGTAGTAAATATTACAGCGCAATCCACGAAAATAACCCTGGCGGTGCTGGTGCTAGTGGCGGTGTAGGTGCGGCTAGTGGCGTAGCCACGACCTCCGGGTTTCTTTCTCCGCAGCAACTGCAACACCAATCGCCTCACCAATCGCACCATTTACAACAATCTCAActtcaacagcaacagcaacaacagcagcttcCACATCATCCTCAGCAGGCACAAGCAGGTGGTGTACAAAGCAAGTCATCTCAGGAACAttctcaacaacaacagcaacagcagcagcagcagcatatgATGAATATGAACAATCAGGAGATGATGGGATATCAGGACATATGGAATGCCAATATGATGAAGATGGAATTTCAGGAGGAAGGAACTGGTGGTAACGGCAACAGCGGGGCGTACAACAGCTTGGGAAATATCTTGACAAACCTAGAAATGATTGGCGGCAGTAGTAACTTCGAGTCAcaagcacaacaacaacagcaacaacaaagcTATGATATGATACCTGCTTCCCGCACAAGCGCCGATCCTCACGTTCAGTCACGAGGACCGTCTGCACAATCACCTGCCGCATTAGCGCAACAGCAAGTACAACAAcagcatcaccagcagcaacaacagttaCATCAACAATCTCATTCGAAAGGAGGTCATTTTCATAGTAAACAACAGTCACAACTCCCAAGTCATGCTCACCTACTATCGTCGGTCGAACCGGGACAGATGGTgaatcagcagcatcatcagcatcagcaacaattgcaccatcaccatcatcagcagcagcaacagcagcaacagcttcaccatcaccatcatcatcatcatcagtcgcaacagcagcaataCTTCCAGGAGCAGCATCACCAACAGGTATTACCCCATTCACATCATTCCGGCTCGATGGGCCACTCGTCAATGGGTGGTAGCCACCATCATCATGCTCAActtcaacaacagcaacagcaacaacagcagcagcaagccaGCCCTCACCAGCAGCAAAACCCACATCATAATccacatcagcagcagcatcatctacatcaacagcagcaacagatgTACAACGCACACATGCCCCATCATCAGCAGCTGGTGCAACATCATCCGCATGCTCCGGGACCACCAGGTGTGGTTCCGGGAGGCGGAagcagtagtagcagcagcagcagcaacagcagcaacaccaacgTACCACCCCATCATCCACAGCATGCTGGTGTGCCCggacaacagcagcagcaagcggTTGGGATGAACTACAACCCGGCGCAGCCCCAGGGGGAGCTTGGTAACGGTGCTTCAAACCAAGCGACGACCTTGCCGGCGGACATGGTGAAAGCGCAGGCAAACAATCTACCCTTTGTCGATAGCTTTACCGAGTCGATCGACTACCTGCAGCAGTCCTTTCAATACGTCTAA
Protein Sequence
MEVKMQHRSRAHMFQIQVRALIKTLKCLQSDDKYQALLFLISAIKLYVKFLYNDCQERLYKPAILKELNNIENVIVVNLLKTRGAGTASASASSVATARTSASSYGGGLASTTRLDLGGTSIRSTDLSLGGDGLLMMHPHRTQPHPPLMPWDLRGKLLRGNLFDGLPPTDSVRLGANISAAACSSLLKGGQRLASAGRWLGNVRMTRALVRMIANHDFKLLFNMFEQSIFPTWKIYKNERIFVRKRPALTTVTVRTSLPAICYGSGSSHSPPATYIKKEEFDFDPPYSIADDHCFEEIKDEDDDDLLLMKEDDSIDISNEIFSEEESSTNNTSLMLSSDTNTLDTNDSSMVSHERNKEQIYQCLLCDKSYRKRKSLVIHFNLHPGYCPDCGKQRGVTSDEIVEHNRIYHKNRPHICEHCGETFTRNQQYQIHVQGHFISQKRVAEQNCKKIHKHCCKTCGIVFNNQKYLEKHIQKTNHQMEGVVCEICGAIFCNSMKLNHHVTRMHNNVFSQKASLERNMLLQQTSTSVVEKSYCCDHCGLSFLSQTTLRDHIKLAHTSVPEDVKSSQTATENKFECNICNKLFAAKRSLKRHKLCHSEERAFRCTVDNCKDAYKNQSHLARHMKTVHHIEPQKRLPKGKAAAATAAAGGGAGGSSGGTSATLSTSTTGDPSRASSASADFISHGIGDGVTIGGGSCDSLKVGGGGVGALKKSALGSSEKSLGDSSTNFSDNMSSFNYEFSDTTGGGSSTPALPSLGGRDEGTPTLLSSAMLGGSGSTMAPRSQAGAFNDPGISFASTSKQQQHNQLQQQHLSWQNLEFGSVPQHRSTTLAGGGGPPTQPMQDPLATQGSFLDTGHPQHHNLHHQAHHPLGPGSMGDPMGGAGAGGGVFMASSNMMPGGARRFPLPDTTLTCEHCDETNFVNAQQFQVHVQDHFVVKEGKEPAGKKLLRLICKTCNLVFATGAQLDRHIQKTNHHTESIACEICSAIFNSNLKVYQHMLKCHKNDIWFACEQCSKVFILKQDYDKHQLVHQTVTDRSIICEHCASSFLTQEALKEHIKIAHSMDKKYKCTICNKLFAARRSLKRHKLCHEEEAAFRCPIDGCTEAFRTAANLAKHKKMAHPAGIVAAPTSQVPGSIVPGVMVAHDSMGESPHVATKLPGTMAGGPLPATASGTMKVLEKVHQEPAVQNAGVGQVMAGHHGTNPLMAVAAGMLKTEPRPSPSMGMVVPPSRTSSAGSSVGLGGNNTNSGSGANLPYNPYEAQGAMHYNSVGLGVSPGSNIGPAGHGHHAALHHHHHHLQQQQQQQQHGGNQHHSSQQALPHHHSQSQFVGMTNPAGAAGLHYTSAHGGSRGGTGGTSGNLEQQQQPSTVGYRMAGEGGASVGPSGGNTGNIPYGYAQMGNAYDWQNMAEMGNQNAGVETGGIVGGANAGQTQVSSASASAMKGAGSKYYSAIHENNPGGAGASGGVGAASGVATTSGFLSPQQLQHQSPHQSHHLQQSQLQQQQQQQQLPHHPQQAQAGGVQSKSSQEHSQQQQQQQQQQHMMNMNNQEMMGYQDIWNANMMKMEFQEEGTGGNGNSGAYNSLGNILTNLEMIGGSSNFESQAQQQQQQQSYDMIPASRTSADPHVQSRGPSAQSPAALAQQQVQQQHHQQQQQLHQQSHSKGGHFHSKQQSQLPSHAHLLSSVEPGQMVNQQHHQHQQQLHHHHHQQQQQQQQLHHHHHHHHQSQQQQYFQEQHHQQVLPHSHHSGSMGHSSMGGSHHHHAQLQQQQQQQQQQQASPHQQQNPHHNPHQQQHHLHQQQQQMYNAHMPHHQQLVQHHPHAPGPPGVVPGGGSSSSSSSSNSSNTNVPPHHPQHAGVPGQQQQQAVGMNYNPAQPQGELGNGASNQATTLPADMVKAQANNLPFVDSFTESIDYLQQSFQYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00109390;
90% Identity
iTF_00109390;
80% Identity
iTF_00109390;