Basic Information

Insect: Anopheles coustani
Gene Symbol: ZFY
Assembly: GCA_943734705.2
Location: OX030901.1:30644740-30648007[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.0017 0.14 12.8 2.3 1 20 154 173 154 176 0.92

2 17 3.7e-05 0.0029 18.1 1.5 2 23 236 257 235 257 0.97

3 17 0.042 3.3 8.5 1.3 2 23 266 288 265 288 0.95

4 17 0.00036 0.029 14.9 5.0 1 23 304 326 304 326 0.97

5 17 0.11 9 7.1 4.5 1 23 332 355 332 355 0.95

6 17 7.7 6.1e+02 1.3 2.5 2 23 371 393 370 393 0.88

7 17 4.1 3.2e+02 2.2 0.2 1 23 467 490 467 490 0.90

8 17 1e-06 8.1e-05 23.0 1.1 1 23 517 539 517 539 0.98

9 17 0.0013 0.1 13.2 1.2 1 23 545 568 545 568 0.96

10 17 0.16 13 6.6 1.1 1 23 579 602 579 602 0.94

11 17 0.00084 0.066 13.8 2.6 1 23 736 758 736 758 0.94

12 17 0.011 0.86 10.3 1.0 1 23 764 787 764 787 0.95

13 17 1.2 93 3.9 2.3 1 23 849 872 849 872 0.94

14 17 0.64 50 4.7 1.4 2 23 888 909 887 909 0.92

15 17 0.00085 0.067 13.8 3.5 1 23 934 956 934 956 0.98

16 17 0.0096 0.75 10.5 0.2 1 23 962 985 962 985 0.95

17 17 0.00025 0.019 15.5 0.3 1 23 997 1020 997 1020 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.0017	0.14	12.8	2.3	1	20	154	173	154	176	0.92
2	17	3.7e-05	0.0029	18.1	1.5	2	23	236	257	235	257	0.97
3	17	0.042	3.3	8.5	1.3	2	23	266	288	265	288	0.95
4	17	0.00036	0.029	14.9	5.0	1	23	304	326	304	326	0.97
5	17	0.11	9	7.1	4.5	1	23	332	355	332	355	0.95
6	17	7.7	6.1e+02	1.3	2.5	2	23	371	393	370	393	0.88
7	17	4.1	3.2e+02	2.2	0.2	1	23	467	490	467	490	0.90
8	17	1e-06	8.1e-05	23.0	1.1	1	23	517	539	517	539	0.98
9	17	0.0013	0.1	13.2	1.2	1	23	545	568	545	568	0.96
10	17	0.16	13	6.6	1.1	1	23	579	602	579	602	0.94
11	17	0.00084	0.066	13.8	2.6	1	23	736	758	736	758	0.94
12	17	0.011	0.86	10.3	1.0	1	23	764	787	764	787	0.95
13	17	1.2	93	3.9	2.3	1	23	849	872	849	872	0.94
14	17	0.64	50	4.7	1.4	2	23	888	909	887	909	0.92
15	17	0.00085	0.067	13.8	3.5	1	23	934	956	934	956	0.98
16	17	0.0096	0.75	10.5	0.2	1	23	962	985	962	985	0.95
17	17	0.00025	0.019	15.5	0.3	1	23	997	1020	997	1020	0.97

Sequence Information

Coding Sequence: ATGGATTCGGAGCCCGAACCAGAGCCGGAGGTCGATGATGATCCAGTGGATGTCCCAAATCAAAACCCCGAGTCGTActgtcggttttgtttttctgaaaCCGACGTCGAGCCGCTCTTTCCGGCGAATCAAAGCAAGCCGGCTAGTGAGATGTACGAACGCCTGTTCGAATGTATTGGCATCAAGCTGACAAAAGAAGACTATTATCCCAGCGGCATCTGTTGGATGTGTTCGCTGACGATGGAGGAATTTCAATGCTTTCGGAAACGCTGCCTCAAGTACGACACTCTGGTGCGTAGGTTGCAGGGACATGTCAAGGATACGGAGTCACCGACTACCACCGAAGCGACAGTTCCACCTCcgagtgaagaaaaacaaagtattAAATTACCCGGTGTTATATTCAGGAAGGgtaaaaaatttaagaaaaaaccaCTCCCAACAGGGGACGCAACGGTGCATCCGTGCCCCTTCTGTCCACGAAGTTTCACCCGGAAAATGTATTTCGATCAGCACATGTGGAAACACCGAGATTTGTTGCAGGCCGCCAAAGCGGACGGTGCTAGTGGTGGAATTAAGAAAACGGTACTCAACAGACCGATAAAGCAGGAGAAACTTTGGATTCCGATTGTGAAACCCGAAACGAACGCATCCACTGACGGTGGGTCGCCGCCTACCGGAGGCAAACTGAAAGATGGATCGATTAGCTGTGAATATTGCCCGCGAAAATTCACACGCAGGATGTACTACATACAGCATCTGCGTAAACACAACGCGGTCAAAGAGGGGGTGGTCCGGTGTCGATACTGCCCGCGAAACTTCGTTTCAACCCGGAGCCGGCGAGCGCacgagaaaaaagaacactaCAAAATTATTGCCGCAGAGAACTCGGGCCCAAAGAAACCTCCCTTCTGCTGCCCGCAGTGTTCGAGAACGTTCAAGTATCGGTATTCCTTACGAATGCATCTACTTAACCACAGTGGCCAGCTGCCGCATGCGTGCGATATTTGCAACTGTCGATTTTACAGCATGCAGTATCTTGCCGTTCACAAAAAGCGCTACCATGGCCCCAATGCTATCTGTGGCGAGGCGGGAAATGAAAGTATTATAAGCTGTCTATACTGCACAAGATCGTTTTTGAGAGAGTGTGATCGATCAAGTCACATCAAGCAGATGCATGCGAACATAGTGTCTGCCCTGAACGAAACGGAAGGCGGTGGTCAGCCAGAGCTTATGGATGACTGCCCACCGGCCGACACCGAGGGACTCACCGACCCAGAGCTACTGCCACCGAACGTTCACGAACCGATGATGGAAATCAAAGAGGAAGAACCGTACGCAAATGATCCCCATCGTTCGGGATTACCGTCGGGCGGCATGGAACCCGATAATCCACTGTTCTATTGCTACTCGTGCGCCATGAACTTCGACACGGAAGATATGTACGCGGAGCATCTGGATGATCAGCATCCCTTCGGAGGTGAACAGATGATGGAACAGCTTCAATCGGGATCGCCGACTGGCGAGCAGGAGCAGGGAGAGAAGGAATTTCGTTGCCCATACTGCCCAAAAACGTTCACGCGGAAATGGTCCATGAACGAACACATAACATCACATCTAGGCACGCGTCGGTACCCTTGCGAGCTGTGTCCGGCAATATTCTGCCGCGAAGGGTACCTGCGCACACATCGATCCCGCAAGCATCCGAACGAAGCGGAAAAGTATAATGGCACGTTCAAGTGTCGCTTCTGTCCGCGAATGTTCGTGATGGAGCGTTACAAAAAGGTGCACGAGAAGATTGCCCACATAAAGAAGGGGGACGTCCTGCCGGAGGATACCGACACTAACAGCGAACTCGCGCTCAACGACAACAGCGTAATGGAGGTGGACGAGAGTAGCTGCAGCGTCATACAGGAAGCGTCGTGCACCTCGAATGATTTCGACCTGCAAAGCATTAGCCCTGAGGAGGCAGAAAGCATAGAATCGCTGCAAAAACTAGTGGTCAAGATTCGACCGATACCCCTGCATGTTCTGGTTGACTATCAATGGCAAATCGAAAGGTACGAAAATATGCAGTTTGACCAGCCGGACACCGCACCTCCATCCGTGGAACCTGACATTATCGATGAATCAACTAATTCATCCTTCCCACAGGACGATTCGGGTGATGTGAACCGAAAGCGCACCAAAATAGGCATCACGCTCCATCCGTGTGGTCTTTGtacgaaaatgttcaaatccCGAACCGCCCTGCGTAAGCATTCGCTGTACCATAGCGGTGCACTGCCCCATCAGTGTGACGAATGTGGCGTGCAGTTTATGCGCTATGGACTGCTGGTAGACCACAAGACACGGTACCACGGTGAAAATGGACCGATGATTGCCGCACGGTATAGTTGCGACTATTGTCCGCGGATTTTCCTTCGCAAGCAGGATCGATCCTGCCATCATCTGATGGTGCACGCGCGTGATCAGGCCAAGGCACTCGAGAACGACATCGATGTGTCACCGACGTTGGGCCATAgtaagaaaatcaaaaaagaTTATCTCTGCAAGGTGTGCGGAGAGTTGTACGAAAAGTATCGCACGTGCAAGCGCCACATTAACCGCGCCCATCCGGCGGCGGAAGGGGAAGAAGATATTAAGCCGATGAAACTCTGCCACTGTGCCATCTGCGCCGGTATCTTCAAGAAGCGGGAAGACTGGAACGAGCACATGGAGCAGCATCCGAAGGTGCAGTGCCACCACTGCGAGCAGTGCATTCGACGGCGACGAAAAAAATGGGGTCGAAAGTTGATCCATCGGTGTAGCTTCTGTCCGAAGGCGTTTTTGCACAAACCAAACCTGAACTCTCATCTGCGCAtacaccagcagcagttgcGCTTTCCTTGCGGTGAGTGTGACGCAATGTACGATCGGTATCGTGACTTGGCCACGCATAAGATACGGTACCactcggatgattcgattGGCCACGCGGCCGCACAGTACAAGTGTGCCTATTGTCCGCGTGTTTTCATGCGTCCTCGAGATGTGAACTACCATCAGCTGTCGGTGCATGCAGACCGAGCGAACCTGGCTCCAGTGGAGCAAGAGGATGACTTAATGTATCTCGATCCAAGCACACTTCTGGACTTGGCGGATCAGGAAATGGACGGCGGAAAACCAATTAAAGTAGAACCAGATTTAGATTAG
Protein Sequence: MDSEPEPEPEVDDDPVDVPNQNPESYCRFCFSETDVEPLFPANQSKPASEMYERLFECIGIKLTKEDYYPSGICWMCSLTMEEFQCFRKRCLKYDTLVRRLQGHVKDTESPTTTEATVPPPSEEKQSIKLPGVIFRKGKKFKKKPLPTGDATVHPCPFCPRSFTRKMYFDQHMWKHRDLLQAAKADGASGGIKKTVLNRPIKQEKLWIPIVKPETNASTDGGSPPTGGKLKDGSISCEYCPRKFTRRMYYIQHLRKHNAVKEGVVRCRYCPRNFVSTRSRRAHEKKEHYKIIAAENSGPKKPPFCCPQCSRTFKYRYSLRMHLLNHSGQLPHACDICNCRFYSMQYLAVHKKRYHGPNAICGEAGNESIISCLYCTRSFLRECDRSSHIKQMHANIVSALNETEGGGQPELMDDCPPADTEGLTDPELLPPNVHEPMMEIKEEEPYANDPHRSGLPSGGMEPDNPLFYCYSCAMNFDTEDMYAEHLDDQHPFGGEQMMEQLQSGSPTGEQEQGEKEFRCPYCPKTFTRKWSMNEHITSHLGTRRYPCELCPAIFCREGYLRTHRSRKHPNEAEKYNGTFKCRFCPRMFVMERYKKVHEKIAHIKKGDVLPEDTDTNSELALNDNSVMEVDESSCSVIQEASCTSNDFDLQSISPEEAESIESLQKLVVKIRPIPLHVLVDYQWQIERYENMQFDQPDTAPPSVEPDIIDESTNSSFPQDDSGDVNRKRTKIGITLHPCGLCTKMFKSRTALRKHSLYHSGALPHQCDECGVQFMRYGLLVDHKTRYHGENGPMIAARYSCDYCPRIFLRKQDRSCHHLMVHARDQAKALENDIDVSPTLGHSKKIKKDYLCKVCGELYEKYRTCKRHINRAHPAAEGEEDIKPMKLCHCAICAGIFKKREDWNEHMEQHPKVQCHHCEQCIRRRRKKWGRKLIHRCSFCPKAFLHKPNLNSHLRIHQQQLRFPCGECDAMYDRYRDLATHKIRYHSDDSIGHAAAQYKCAYCPRVFMRPRDVNYHQLSVHADRANLAPVEQEDDLMYLDPSTLLDLADQEMDGGKPIKVEPDLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109362;
90% Identity: iTF_00109362;
80% Identity: iTF_00109362;