Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:3766258-3769262[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2.6 2.1e+02 2.8 1.1 2 23 221 243 221 243 0.94

2 16 0.0018 0.15 12.7 0.2 2 20 253 271 252 273 0.94

3 16 0.92 73 4.2 1.2 1 21 280 300 280 301 0.93

4 16 0.15 12 6.7 2.0 2 23 406 428 406 428 0.94

5 16 5.3 4.2e+02 1.8 1.3 2 20 439 457 438 459 0.92

6 16 0.99 78 4.1 2.9 1 22 466 487 466 491 0.90

7 16 0.0012 0.093 13.3 2.0 2 23 568 590 567 590 0.92

8 16 0.7 55 4.6 0.0 2 21 604 623 603 624 0.90

9 16 0.0041 0.32 11.6 2.2 1 21 633 653 633 654 0.94

10 16 0.18 14 6.4 2.8 2 23 722 746 721 746 0.86

11 16 5.5e-05 0.0043 17.5 2.4 1 23 790 813 790 813 0.96

12 16 2.6e-06 0.0002 21.7 0.5 1 23 820 842 820 842 0.98

13 16 5.8e-05 0.0045 17.5 0.4 3 23 850 871 848 871 0.97

14 16 8.1e-05 0.0064 17.0 1.1 1 23 877 899 877 899 0.98

15 16 0.00016 0.013 16.0 4.4 1 23 905 928 905 928 0.98

16 16 4.9e-05 0.0038 17.7 1.1 1 23 934 956 934 956 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2.6	2.1e+02	2.8	1.1	2	23	221	243	221	243	0.94
2	16	0.0018	0.15	12.7	0.2	2	20	253	271	252	273	0.94
3	16	0.92	73	4.2	1.2	1	21	280	300	280	301	0.93
4	16	0.15	12	6.7	2.0	2	23	406	428	406	428	0.94
5	16	5.3	4.2e+02	1.8	1.3	2	20	439	457	438	459	0.92
6	16	0.99	78	4.1	2.9	1	22	466	487	466	491	0.90
7	16	0.0012	0.093	13.3	2.0	2	23	568	590	567	590	0.92
8	16	0.7	55	4.6	0.0	2	21	604	623	603	624	0.90
9	16	0.0041	0.32	11.6	2.2	1	21	633	653	633	654	0.94
10	16	0.18	14	6.4	2.8	2	23	722	746	721	746	0.86
11	16	5.5e-05	0.0043	17.5	2.4	1	23	790	813	790	813	0.96
12	16	2.6e-06	0.0002	21.7	0.5	1	23	820	842	820	842	0.98
13	16	5.8e-05	0.0045	17.5	0.4	3	23	850	871	848	871	0.97
14	16	8.1e-05	0.0064	17.0	1.1	1	23	877	899	877	899	0.98
15	16	0.00016	0.013	16.0	4.4	1	23	905	928	905	928	0.98
16	16	4.9e-05	0.0038	17.7	1.1	1	23	934	956	934	956	0.99

Sequence Information

Coding Sequence: ATGCCGAAAACAGGAGAGCTGATGCGTTGTTGTATCTGCtgtaaacaaaaagcaaaggaTGACCTATACGATCTGGCCATATCTGTTGATATGTCGGATGGGAAATCTTCGTGTACGATTGCAGAGATGATTGAAACAGTAGCTTCAATAAAGCTCAAACCAGTACCACAGTCTGTTTGTGAGGCATGTTGGAGCTATGTGAATGCAGCACATATAATTCGTGACAAAATTCGCCGCTCGAAATACCTGCAAAGATACAGTGAAAATGAACATGGCAACGATACGATTGACGAAATTGCTGCAAACTTTGAGATTTTAGCAGAGGATAGCTCAGTGAAGTGTCCAGAGGAAGATTATGAATGTGAATATCTCGATGAATATCTCGagccaaacaaaccgaatgaTCACACGTACGAGAGCCGGCGGGACGAGGAACCGGGGGAAAAGGAGGAGGAAGTGGAAGATAGTGCGAATCACAAGAGTATACCTTCTAGCAGGGCAATCTTGCTTGACGCTTCGATTGTAAAAGATGAAACAGTTCTTGGCGATCCATGCCCAAGTGACCTTCATATTACGCGTCAGTTTGAAGAACCTCGTACACAGTTTATACAGCGGGATGAATTCCACAACCAGTACCGATTGCTGGAAGTAACCGGAGAACGTTGCTGTGGATGTAGCTTTGTCGCGGAAAATCGAAAAGAACTCTTGCAACACTCGGAAACGGTTCATGCAATTGATATCACAGACAGTGGAGATTACTGTCCGATTTGTTTCTACAAGTTCGCTACCGATCAGCATTTGGAGCGACATATAGAAGAGTTCAAATCGACCATGGTATACGTCTGTTTGCAGTGCAATCGGTTCTACAATCTGCGTCAAAAGATGTTCAACCATTTGCTGAAATGTGGAGAAAGCATCTCCGTGTTATCGGCGGACGAATCAGACgcggaggaaaatgaaaacctgGACAATGAGGAAGAGTACTATGAAGAAATCATTGAAGATATGTATAGTAACCTGAACTCACCGGCCAACGATAGCCTAATCGAATCGTATCAACGGAAGATGATGCGCTGCCGGGCACTGTTCGATGAGATAACATCGAATGAAACCTTTTCCTGTAAGCTAGATGAAGCGGAGTTGAATGTACAGGATGTTCAAATCATAGACCAGTGCACCTTCGAGACGTTCAAGTTTGTTCGCCTTCGCGGGGAACGTTGCTGTGGATGTGCATACACGTGCGCTACCAGAGGACAGCTGATGCAGCATGGGAGGGCCATTCACGCGTCTGATAAAAACCTGCAGGATGATCTCACGTGTTGTCTGTGTGGAAGTCAGTTTCATGTCGAGAGCGAAATGGTTAAGCATCTGAGCTTTTTCACGAGTAAAGAACTATTTTTCTGTACCATCTGCAACGAGTCGTTCCTTTGTAGGGAAAGTTTAAAGACTCACCAACAGACGAACGAAAGCCACCAAGAGCAGCAGCGGAAAAAGTTCCAGGATACTGATATCGAAATGTTTGGGTCCGGTATGTTCATCGAGCTTGACATGCCGTTGGTTATTGAGCAGCTGGATAGGTTGCAAGCCGAGAAGAATATCAACCGCCCGAAATACATACGCTGCATACCGATGCCGGAAGAGCGCTTCATCCAGAATATTACGGAGTATACAAATTACTCCATACTGACGGTCGTTGGTCAACGGTGCTGTGGTTGTGGCAAGTTCTTCGACACGCTGGGAGATTTGAAACAACATTCCCAGCAGGAGCATACGATGTCGATAGCATCGAGTTGGATTAGCGATCAGCTTCAATGCGATATCTGCTACGCTGTGTTCGATTTCGAGCGTGGGCTTATATTGCACAAGTCAACCAGACGTAACAACAAGACAAACCTTTATCTCTGCAAACTGTgcggacttctttttacgaaAAAATATTGTCTAGCTCGGCACATGCAGTTTGCACCGAATCATTTATCGGAATTGATTGTCCATGCCAGTGGTAGAGGCACCAGCGAAGCGGATGGACAGGACGAAAAGGGACTGGATGATGCCGAAATTAACGACCCGGCAGAATCGGATCCACGTGTTAGCGAAGCGTTGCAGCTACACAAATCGGTCCAACAGGCTGGCTTAGAGAAGGTAGGACATTTTGTGGGCTATCATTGCTGCTTTTCCAAATGTACCGCAACCTTCAGCAACGAGGAAGATTTGGTCGAGCACTCGCGAGACGAACATAATGGCAAACGACAAGAGAATGAGACCGAACGAAAGTCGGACAAGAACATTTGCCCGTCTTGCTGTAAATCGTACCAGGATCTTGTAAAACTGGCATGGCACCGGTTTCAGCGGTTTGTACCCCGACAGTACAACTGCAAACACTGCGATAAAACGTTCGACAAATATCCAAACCTGAAGCTGCACGTGGATACTGAACATAGTGAAACCCCTTCCAACTACGTATGCTCGGTATGTGATAAATCGTTCGTGTTGAACTCCCGTCTGAAGGCGCACATGAAACTGCACACGTCACAGAAGGACTATGGGTGCGATATTTGTGGAGTCAAATTTCGAAGCAACGGATTGATGAAGCGTCATCGGCGGTCGGTGCACTCTACGGAACGTCCGTTCGAGTGTAAGCTCTGTCCGAAACGGTTTCGCGTTATAGagaaattcaaaattcatcAACGTGTTCACACCGGCGAGAAGCCGTTCGAGTGCACATACTGCCAACGGACGTTTAGTCACTTTACCGACCGGAAGCGACATATAATGACCGCCCATACCGGCGAGCGACCCTTCAAATGTTCGTACTGCACCGCGGCGTATATTCGCAACCGAGAACTTACACTCCATATGCAAAAACATAAAGATATTATACAAAACCAAGCCAGTGTAGTGAAGGAAGAGTGTAGCTATGAGAGTGGATAA
Protein Sequence: MPKTGELMRCCICCKQKAKDDLYDLAISVDMSDGKSSCTIAEMIETVASIKLKPVPQSVCEACWSYVNAAHIIRDKIRRSKYLQRYSENEHGNDTIDEIAANFEILAEDSSVKCPEEDYECEYLDEYLEPNKPNDHTYESRRDEEPGEKEEEVEDSANHKSIPSSRAILLDASIVKDETVLGDPCPSDLHITRQFEEPRTQFIQRDEFHNQYRLLEVTGERCCGCSFVAENRKELLQHSETVHAIDITDSGDYCPICFYKFATDQHLERHIEEFKSTMVYVCLQCNRFYNLRQKMFNHLLKCGESISVLSADESDAEENENLDNEEEYYEEIIEDMYSNLNSPANDSLIESYQRKMMRCRALFDEITSNETFSCKLDEAELNVQDVQIIDQCTFETFKFVRLRGERCCGCAYTCATRGQLMQHGRAIHASDKNLQDDLTCCLCGSQFHVESEMVKHLSFFTSKELFFCTICNESFLCRESLKTHQQTNESHQEQQRKKFQDTDIEMFGSGMFIELDMPLVIEQLDRLQAEKNINRPKYIRCIPMPEERFIQNITEYTNYSILTVVGQRCCGCGKFFDTLGDLKQHSQQEHTMSIASSWISDQLQCDICYAVFDFERGLILHKSTRRNNKTNLYLCKLCGLLFTKKYCLARHMQFAPNHLSELIVHASGRGTSEADGQDEKGLDDAEINDPAESDPRVSEALQLHKSVQQAGLEKVGHFVGYHCCFSKCTATFSNEEDLVEHSRDEHNGKRQENETERKSDKNICPSCCKSYQDLVKLAWHRFQRFVPRQYNCKHCDKTFDKYPNLKLHVDTEHSETPSNYVCSVCDKSFVLNSRLKAHMKLHTSQKDYGCDICGVKFRSNGLMKRHRRSVHSTERPFECKLCPKRFRVIEKFKIHQRVHTGEKPFECTYCQRTFSHFTDRKRHIMTAHTGERPFKCSYCTAAYIRNRELTLHMQKHKDIIQNQASVVKEECSYESG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109340; iTF_00107868;
90% Identity: iTF_00109340;
80% Identity: iTF_00109340;