Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:23644595-23646594[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00082 0.065 13.8 0.2 2 23 252 273 251 273 0.94

2 11 0.11 8.4 7.2 1.3 2 23 311 333 310 333 0.93

3 11 0.00028 0.022 15.3 0.8 1 23 339 361 339 361 0.98

4 11 6e-06 0.00047 20.6 1.2 1 23 369 391 369 391 0.98

5 11 1.6e-06 0.00013 22.4 1.0 1 23 397 419 397 419 0.99

6 11 0.11 9 7.1 0.5 1 23 426 448 426 448 0.95

7 11 1.5 1.2e+02 3.6 0.1 4 23 479 498 476 498 0.91

8 11 8.6e-06 0.00067 20.1 1.9 1 23 502 525 502 525 0.94

9 11 4.1e-05 0.0032 17.9 4.8 1 23 531 553 531 553 0.98

10 11 3.1e-06 0.00025 21.4 4.6 2 23 560 581 559 581 0.97

11 11 2.2e-05 0.0018 18.8 0.5 1 20 587 606 587 608 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00082	0.065	13.8	0.2	2	23	252	273	251	273	0.94
2	11	0.11	8.4	7.2	1.3	2	23	311	333	310	333	0.93
3	11	0.00028	0.022	15.3	0.8	1	23	339	361	339	361	0.98
4	11	6e-06	0.00047	20.6	1.2	1	23	369	391	369	391	0.98
5	11	1.6e-06	0.00013	22.4	1.0	1	23	397	419	397	419	0.99
6	11	0.11	9	7.1	0.5	1	23	426	448	426	448	0.95
7	11	1.5	1.2e+02	3.6	0.1	4	23	479	498	476	498	0.91
8	11	8.6e-06	0.00067	20.1	1.9	1	23	502	525	502	525	0.94
9	11	4.1e-05	0.0032	17.9	4.8	1	23	531	553	531	553	0.98
10	11	3.1e-06	0.00025	21.4	4.6	2	23	560	581	559	581	0.97
11	11	2.2e-05	0.0018	18.8	0.5	1	20	587	606	587	608	0.95

Sequence Information

Coding Sequence: ATGCATGTTTGTCGCTTCTGTCTCCGATGGACGGAACCTACTGTGGACGTAGAAGATCAGGTGTTACTggtaaagaacatttttggtCTCGAGATAGATTGTGCCACCTGGTTTCCTCGGAATGTGTGTGAAGAGTGCTGTACGCGGCTAGAGCAGTGTGTTCAATTTTATGAACAGGTAATGAAGGCAGAAAGGTCACTCCAGAACCTCCACGAAGGTGGTGTGCTGGAGCCACTGTTGGCCGAACCTAAGGAAAGCGGTGAACCATTTGGTGGTATTGATTTATCTCCCAAAGAAAATGCTGATGAGAGCGATCCAGCCTACTACGTAATGGATGAGATTGACGATAATCAACCGGCTCAGCCGCTGCACGAGGATCTGGGCGGTGGATATAAGGATTTAATCGAGGAACCTATGAGTATGCTACCAAAAGAGAGGCTGGTAGAAATTCAGATTGAAGCTGTTGAAGAACTCGAAATAGTGTGTGCACCAACGAAGACGAATGAGGTGCATTATCAACAGGAACACCTTTTGCCCTTTGTGCAACAAGTACGTGAAGACAAACAGGTTGGTGGTATTGAAAAATCAAGTAACGGAATGCTGCATTATGAATCAACTAACAAATCGGAATCTAGAATAGTTGATGAAGATACCAAAGAAGCTTGTCAAAGCAGGCTTGGTCGTGAAACACGTAGTGCTAAATCCGCATCCAACATGAAAGTGCCAACGGAAAAGATCGATAGGATTCCTAACAAATGCTTTATCTGTGATACGGTGTTTGCAACCGTAACGGAACTACAAAGTCACCTGTACGACCACGAGAAAATACTGCCCTATCGTTGTGATAAATGCAGCACGGCGGAACATCCGATCGAAATACGTACCATCATTTCCCTAAACAATCATCTTGAAACGCATCGTTACAAATTAGTATGTAACCGGTGTCCGTTGCGATTTCGAAGTTATACCAGCTGGTATgagcacaacaaaaaaaggcatTCCGAGCTCCGGTCCTACACTTGCAATTTGTGCGGGATGAATTTTGAGGTGAACCGTAAATATTTGAAGCACATGAACGGCCACCGGAATAAGCAGATGGGGCGATACAAATGTACCACGTGCGCGAAGGTATTTGAAACCTCAACTGAGCTGAAACGGCACGAGAAGATTCACTTGAGTCAACCCGTCTTCAAATGCCCGGACTGTACGCGTGGATTCAATCAAGAGTGGAGCCTAAAACTGCATCAACGAAGGCACCGTCAGCATAGCGAGGTGTACCGGTGCATCCAGTGTCCCGGGAAATATGCAAATTTCACCGATTGGAGACGCCATATGAAGGAGCACTTTCCGGAGGATGAGCGTTACTGGGAGCTGCAAGATGTGCTGCCTGCCTCGTTGCAGGATGCGGGCGAGTATCCGAAGGGTTGCGCTGAACCGGGCTGCACCTACGTGGCCTCCTCGTTGCAGTTGATGTGGATGCACTATCGCACTCACTATAAGGCGTTTGAGTGTCAGCATTGTCCTCGGAAGTTCTCAAACACGACGAATCTACGACAGCACATCGATCTGGTTCACCGTGGCTTAAGACCACACGAGTGTGGGAAATGTGGAAAACGCTTCGGCTACCGCCATAAGCTGAAGGAACACATGAACATGCACGACGGGGTGCGCAACCTACAGTGTAGGTACTGCGAGAAAAGTTTTACCCATAGCTCGCACTTGACCGTCCACGAGCGGGTGCACACGGGTGCAAAACTGTACATGTGTGATCTTTGCGGTCGACGGTTTCGAACGTCATCGGCATTCGCGAAGCACCGGTCCCAACAGGATCAAACCACTGGTGTCCATGTGGCGAGTACACGTTGTGTACAACAGCAGTTCAAACAGTTGCAACAACATCAACCGCAGGTTGATGAGAGCATCTGA
Protein Sequence: MHVCRFCLRWTEPTVDVEDQVLLVKNIFGLEIDCATWFPRNVCEECCTRLEQCVQFYEQVMKAERSLQNLHEGGVLEPLLAEPKESGEPFGGIDLSPKENADESDPAYYVMDEIDDNQPAQPLHEDLGGGYKDLIEEPMSMLPKERLVEIQIEAVEELEIVCAPTKTNEVHYQQEHLLPFVQQVREDKQVGGIEKSSNGMLHYESTNKSESRIVDEDTKEACQSRLGRETRSAKSASNMKVPTEKIDRIPNKCFICDTVFATVTELQSHLYDHEKILPYRCDKCSTAEHPIEIRTIISLNNHLETHRYKLVCNRCPLRFRSYTSWYEHNKKRHSELRSYTCNLCGMNFEVNRKYLKHMNGHRNKQMGRYKCTTCAKVFETSTELKRHEKIHLSQPVFKCPDCTRGFNQEWSLKLHQRRHRQHSEVYRCIQCPGKYANFTDWRRHMKEHFPEDERYWELQDVLPASLQDAGEYPKGCAEPGCTYVASSLQLMWMHYRTHYKAFECQHCPRKFSNTTNLRQHIDLVHRGLRPHECGKCGKRFGYRHKLKEHMNMHDGVRNLQCRYCEKSFTHSSHLTVHERVHTGAKLYMCDLCGRRFRTSSAFAKHRSQQDQTTGVHVASTRCVQQQFKQLQQHQPQVDESI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107850;
90% Identity: iTF_00109324;
80% Identity: iTF_00109324;