Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:90798600-90800971[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00013 0.01 16.4 3.5 1 23 322 344 322 344 0.97

2 9 6.2e-08 4.8e-06 26.8 1.3 1 23 350 372 350 372 0.99

3 9 0.00018 0.014 15.9 3.3 1 23 381 403 381 403 0.98

4 9 0.031 2.5 8.8 0.3 1 23 409 432 409 432 0.97

5 9 0.00055 0.044 14.4 2.4 2 23 474 496 473 496 0.96

6 9 5.3e-05 0.0041 17.6 1.1 1 23 500 522 500 522 0.92

7 9 1.9e-06 0.00015 22.1 4.2 1 23 528 551 528 551 0.98

8 9 2.4e-05 0.0019 18.7 2.1 1 23 575 597 575 598 0.96

9 9 0.0012 0.095 13.3 0.2 2 23 606 628 606 628 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00013	0.01	16.4	3.5	1	23	322	344	322	344	0.97
2	9	6.2e-08	4.8e-06	26.8	1.3	1	23	350	372	350	372	0.99
3	9	0.00018	0.014	15.9	3.3	1	23	381	403	381	403	0.98
4	9	0.031	2.5	8.8	0.3	1	23	409	432	409	432	0.97
5	9	0.00055	0.044	14.4	2.4	2	23	474	496	473	496	0.96
6	9	5.3e-05	0.0041	17.6	1.1	1	23	500	522	500	522	0.92
7	9	1.9e-06	0.00015	22.1	4.2	1	23	528	551	528	551	0.98
8	9	2.4e-05	0.0019	18.7	2.1	1	23	575	597	575	598	0.96
9	9	0.0012	0.095	13.3	0.2	2	23	606	628	606	628	0.94

Sequence Information

Coding Sequence: ATGAAGTGTGCCGTACCCGGTTGTGATACGGATGATAATGTTGTCAGTTCCACGTCTGCGTTCTTTGTCAGGTTTCCCGAGGAATGGCAGGCACAGGAACAATGGATCACCATGTTGAGCATCACTGATCCTGCCTTGGTAGCAGCGCTGCTAGCTGGAGAAATGAAAGTATGCAGCTGCCACTTCAGTGAAGATTGTTTCGGAAAGCATCCGCTTTACGGCTATCGGTACCTTCTGCcagaagcaattcctacgatTTTGCCGAAATACCCAGATCTCTTACCCTTGGTCAATCAAGTCAGGCCAAATAGTTATGTACTATACGATGATACCGACACATCTTCCCCGATTGGGCATGACGTATCAGATATTCTCGCCAGTGAGGACAATGTTGCACCGAACATTGATGAAACTTCAGATCAGGATAATGATATTGAAGACGACCTAGAGGAGATTGGAATCAAATATGAGAATGGGAAGTACTATTTTTACCAACTGGATGAGGATGCCACGTCGGAAACCAACGACGAGCCTGTGGCGAAGGATGACGAGCTGGTATCTTCTGAAGAATTAATCCGCAATGTAAATTATCCTTTCACAAATGATGAACAAACGTCGTGTGATATTTCGGAAAGCATGGTCCTCAAAGAAGAATTACACGCGTCGTTAGAACAAATTGGAGGCGACGGAAATCTTGTCGATGAACTCGCCGAAGAAGGAAAGTTCTCCCAACCCGTCAATTTTGATGCCGATCAGCTCGAGGAAAACGAATCCGATCAGGACAGTCCCAGTCGTGAAGAGCTACTGGACGAGGACTTACAAGAATATTTCGCTgatcatttggttgatgatGTCACATCCTCACACTGTTCAGAGGAGGAGGATGTGATTGAAGCGCTTGATGGTGTGTCCTTGATTGGAAGAGTCTTTCCTGCGAAGGTCtcaaatgaaaaaatcgaACGCTATTGTTGCGATTTTTGTGGAAAAAGATTCCAATATCCGAGCCAAATGAAGAAGCATGTGGTCACTCACACCAAGGCGAAGCCATTCAAATGTGATCAATGTGGGAGAAGTTTTGGGCAAAAAATTAACCTAAAAATTCACATGCGCCGGCACACAGGAGAGCGTCCCGAGCCAAAGTTTACCTGCGAGGCATGCGGCAGAAAGTGTTACCGCCAGAGCGAATTTGAGAAACATCTCAACAGTCATCGGAAAAAATTTCCCTTCGAATGTGTGATCTGTGAATCGCGCTTCATGAACGTGACCTCGTTGTACATCCATCTCCGCCAGGACCATAAAGACAAAGACATCTCGATGCAGGAGACTCTGGAAAGGTTTGCCGAAACTAACGAGGTGCAGATCTTCGACGACAAGCAGGaagagaacgaaaacgaaacgctGCATTCGGATGGCCGCTGGGAGTGCACGGTATGCAAGCAGCGGTTCCGATACGTAAAGCTTCTCCGCAAACACAAGCGTAAGATGCACCCGAAGATATACTCCTGTCGGTACTGTCCGCGCAATTTCGCGTACCGGAGCCAGCTGGAAAAGCATCTACCAACGCATACGCACGAGAAGCGATTCAAGTGTGGGAAGTGCAGCACCAAGTTCTCGCAACGTTCCAACCTTAACAAGCATATGTATACCAAGCACGGCGTAACCGTACCGTGGGATGCCCTGCAAGACGTCCTGATGGAGTGTGATACGGAAACCAAGGTGTCGTATGAGTGCTCACGGTGTGTTAAGTCGTTCTCCCGAAAGAGCACCTGGCTGGCGCACCTCGAGACACATCACACCAACAACGATTTGCAGCCCACGTGTGGACTGTGTAATATGTCATTCGCGTCAACCGCCTTGCTCACCTCCCACATGGGAAGGGAACACATTTCGGTGAAGAAACTGTCGCCACAAAAGCTGCTCATCAACATTCAAACGGCCACGGTAAGCCTTCGTGAGTCGCTGTTGTTTGATGCATATGAGGGTGAAATGGAGGAGGGATATGGTGAGGTGGAGCAGTACATTGACGAAGAACAGGATGTTGAGGACGAGAGTGAGGAAATAGGAGACTATTACACTACTAACATGCTACAAGACAAAATTGATTAA
Protein Sequence: MKCAVPGCDTDDNVVSSTSAFFVRFPEEWQAQEQWITMLSITDPALVAALLAGEMKVCSCHFSEDCFGKHPLYGYRYLLPEAIPTILPKYPDLLPLVNQVRPNSYVLYDDTDTSSPIGHDVSDILASEDNVAPNIDETSDQDNDIEDDLEEIGIKYENGKYYFYQLDEDATSETNDEPVAKDDELVSSEELIRNVNYPFTNDEQTSCDISESMVLKEELHASLEQIGGDGNLVDELAEEGKFSQPVNFDADQLEENESDQDSPSREELLDEDLQEYFADHLVDDVTSSHCSEEEDVIEALDGVSLIGRVFPAKVSNEKIERYCCDFCGKRFQYPSQMKKHVVTHTKAKPFKCDQCGRSFGQKINLKIHMRRHTGERPEPKFTCEACGRKCYRQSEFEKHLNSHRKKFPFECVICESRFMNVTSLYIHLRQDHKDKDISMQETLERFAETNEVQIFDDKQEENENETLHSDGRWECTVCKQRFRYVKLLRKHKRKMHPKIYSCRYCPRNFAYRSQLEKHLPTHTHEKRFKCGKCSTKFSQRSNLNKHMYTKHGVTVPWDALQDVLMECDTETKVSYECSRCVKSFSRKSTWLAHLETHHTNNDLQPTCGLCNMSFASTALLTSHMGREHISVKKLSPQKLLINIQTATVSLRESLLFDAYEGEMEEGYGEVEQYIDEEQDVEDESEEIGDYYTTNMLQDKID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109316;
90% Identity: iTF_00109316;
80% Identity: iTF_00109316;