Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030901.1:82146593-82148319[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 6.6e-06 0.00052 20.4 3.4 1 23 138 160 138 160 0.98

2 9 1.4e-07 1.1e-05 25.7 1.4 1 23 166 188 166 188 0.96

3 9 7.3e-05 0.0057 17.1 2.3 3 23 202 222 200 222 0.95

4 9 2.5e-05 0.0019 18.6 1.8 1 23 228 250 228 250 0.99

5 9 2.8e-07 2.2e-05 24.7 1.4 1 23 256 278 256 278 0.97

6 9 7.1e-06 0.00056 20.3 0.3 3 23 286 306 284 306 0.97

7 9 0.0035 0.27 11.9 0.3 1 22 312 333 312 333 0.97

8 9 0.00022 0.017 15.6 7.0 3 23 342 362 340 362 0.98

9 9 0.076 6 7.6 0.4 1 23 368 391 368 391 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	6.6e-06	0.00052	20.4	3.4	1	23	138	160	138	160	0.98
2	9	1.4e-07	1.1e-05	25.7	1.4	1	23	166	188	166	188	0.96
3	9	7.3e-05	0.0057	17.1	2.3	3	23	202	222	200	222	0.95
4	9	2.5e-05	0.0019	18.6	1.8	1	23	228	250	228	250	0.99
5	9	2.8e-07	2.2e-05	24.7	1.4	1	23	256	278	256	278	0.97
6	9	7.1e-06	0.00056	20.3	0.3	3	23	286	306	284	306	0.97
7	9	0.0035	0.27	11.9	0.3	1	22	312	333	312	333	0.97
8	9	0.00022	0.017	15.6	7.0	3	23	342	362	340	362	0.98
9	9	0.076	6	7.6	0.4	1	23	368	391	368	391	0.94

Sequence Information

Coding Sequence: ATGGCGTCTGCAGAAATAGAGGATTTAATCTTTGGTGAAATATGCCGTTGCTGCATGGCTAGTAAACCGAGGATGAAGCCGCTGTTCGACAACAACCTGCATGCCATGTTGAGCGCTGTTACTGGGCTGCAGTTAAGCAAAAACGATGGTCTACCATCACAACTATGCGTACCCTGTGTGTTGCAGGTTCGTCGGGCCCACTTCTTCAAGGTGCAGTGCGAACAAACCGACAGTGCGCTTCGTAATTACGTGATTGAATCAAAGTTTTCGGAAACGGAAGAGCAACAGCTCAGCCCGAAGCTTGAGGAAAAAGTTAGCGTGAAGGAGGAATTACTGGACGAACCCGATACAGCTGCAAGTGACGAGATTGACGCTGAACCGAATGGTGTTAAGGTCAAAGTGGAGAAACTATATCACTGTCCGCAGTGCTCAAAATCTTTCGAGATGGAGCGAAAACTGAAGCGCCACATGCGAATTCACACGTCTGAGCGACCACACGCCTGTCCAGAGTGTGACATGACGTTTGTGGAGAAATCCAACCTGTCGAAGCATATGCGTAAACATACAGGTGAGCTGCGGAACTCAACCGGGAAACCCCACCTTTGCTCGGAGTGTGGCAAGGCGTTCAAATACGGCACATCGCTGTCGCGCCACCGGAGGCTCCATGCCAATCGCAATCTGTTCACCTGCCACATCTGCTCTAAGGCGTACGTCGAGCAGCAGACACTGGATATGCACATGCGAACGCACACAAACGAGCGTCCGTTTGCATGTCCTAGCTGCGACAAATGCTTCGCCCAGAGAGTAAATCTCGAGCGTCACGAACGGACACATAGCGGTGTAAAACCTTACGGTTGCGACGTGTGCGGCAACAGTTTCACCCAGAAAAGCTACCTTATCATCCATAAGCGAATACACACGCAAGAAAAACCGTACGAGTGTCTTAACTGTTCGGCACGTTTCATCTCGCGTAATGCTATGATGAAGCACCAGCGGACACCCTGTTCAAACAGGCCATATTGGTGCACCTACTGCAAGAAATCGTTCCGATACAAAAAATGTCTCCGTACGCACCGGCGAAATCATTTGCTTGAGAGTCCGCACGCGTGCCAATACTGCGAGTCAAGGTACATGAGCGCGGTCAAGCTGGTGGCTCATATCAAGGCGAAACATCCGAATGTTCCGTGTCGCGCTGAAGACTACGGAGTGGACGAATCCAACCGCATGCGACGGAAGAACATCCAGAGACGAAACTCCAAGCCTCGGTCACAGCCAGAGGAAAGCGAATACGATGAGCTGAGCGTGGGAGATGAAAATGAAGACGGAGAAGATATTGAGATCGCTTGTGTCGGGATATTGgacgaggaagaggaagaagaaagtgCTGGTCAACATAGCCGGGACGAAGAAGTTGTGCACGTAATGTTCAACGGGGACGGAGAGCCGGAGGTTTTAGAACATCCTGACGAACCGGACGATCAATACGCGGCTAGTTCAGACATTCGGCACGGGTCACTGTTGGACATTCAGATTATGAATCCGGAAGAAGAAGATTCGGACATTGAACAGTAG
Protein Sequence: MASAEIEDLIFGEICRCCMASKPRMKPLFDNNLHAMLSAVTGLQLSKNDGLPSQLCVPCVLQVRRAHFFKVQCEQTDSALRNYVIESKFSETEEQQLSPKLEEKVSVKEELLDEPDTAASDEIDAEPNGVKVKVEKLYHCPQCSKSFEMERKLKRHMRIHTSERPHACPECDMTFVEKSNLSKHMRKHTGELRNSTGKPHLCSECGKAFKYGTSLSRHRRLHANRNLFTCHICSKAYVEQQTLDMHMRTHTNERPFACPSCDKCFAQRVNLERHERTHSGVKPYGCDVCGNSFTQKSYLIIHKRIHTQEKPYECLNCSARFISRNAMMKHQRTPCSNRPYWCTYCKKSFRYKKCLRTHRRNHLLESPHACQYCESRYMSAVKLVAHIKAKHPNVPCRAEDYGVDESNRMRRKNIQRRNSKPRSQPEESEYDELSVGDENEDGEDIEIACVGILDEEEEEESAGQHSRDEEVVHVMFNGDGEPEVLEHPDEPDDQYAASSDIRHGSLLDIQIMNPEEEDSDIEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107844; iTF_00109304;
90% Identity: iTF_00107844; iTF_00109304;
80% Identity: iTF_00109304;