Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:15798577-15803467[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00027 0.022 15.3 1.8 1 23 224 246 224 246 0.94

2 15 0.0045 0.36 11.5 0.4 1 23 252 274 252 274 0.97

3 15 0.00047 0.037 14.6 0.1 1 23 469 491 469 491 0.98

4 15 0.0039 0.31 11.7 0.9 1 23 497 520 497 520 0.97

5 15 3e-05 0.0024 18.3 0.5 1 23 564 587 564 587 0.96

6 15 0.0014 0.11 13.1 0.6 3 20 650 667 648 669 0.92

7 15 0.33 26 5.6 1.0 1 23 677 700 677 700 0.92

8 15 0.028 2.2 9.0 2.0 2 22 708 728 707 729 0.89

9 15 0.047 3.7 8.3 10.1 1 23 735 757 735 757 0.95

10 15 0.0034 0.27 11.9 0.3 2 23 763 784 762 784 0.97

11 15 8.8e-06 0.00069 20.0 0.6 1 23 790 812 790 812 0.98

12 15 0.00096 0.076 13.6 0.2 1 23 818 840 818 840 0.97

13 15 0.00074 0.058 14.0 0.4 3 23 848 868 846 869 0.95

14 15 0.54 43 4.9 0.0 1 23 883 905 883 905 0.96

15 15 0.024 1.9 9.2 0.0 1 20 1550 1569 1550 1572 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00027	0.022	15.3	1.8	1	23	224	246	224	246	0.94
2	15	0.0045	0.36	11.5	0.4	1	23	252	274	252	274	0.97
3	15	0.00047	0.037	14.6	0.1	1	23	469	491	469	491	0.98
4	15	0.0039	0.31	11.7	0.9	1	23	497	520	497	520	0.97
5	15	3e-05	0.0024	18.3	0.5	1	23	564	587	564	587	0.96
6	15	0.0014	0.11	13.1	0.6	3	20	650	667	648	669	0.92
7	15	0.33	26	5.6	1.0	1	23	677	700	677	700	0.92
8	15	0.028	2.2	9.0	2.0	2	22	708	728	707	729	0.89
9	15	0.047	3.7	8.3	10.1	1	23	735	757	735	757	0.95
10	15	0.0034	0.27	11.9	0.3	2	23	763	784	762	784	0.97
11	15	8.8e-06	0.00069	20.0	0.6	1	23	790	812	790	812	0.98
12	15	0.00096	0.076	13.6	0.2	1	23	818	840	818	840	0.97
13	15	0.00074	0.058	14.0	0.4	3	23	848	868	846	869	0.95
14	15	0.54	43	4.9	0.0	1	23	883	905	883	905	0.96
15	15	0.024	1.9	9.2	0.0	1	20	1550	1569	1550	1572	0.94

Sequence Information

Coding Sequence: ATGGATCAAACATACTCGATATGGCCTGTAAATACCGGTCAAACGTCTGGCAATGTAGGATCATCCATCATTGCCGCCGCGGTGCCTCCCGGAAGGCAACTTAGAATAGTGAATATTGGAAGCCAGATTACGTCGGATCAACTGATGGGAACGGGAATTGTGACAACTGGTGGTAGCAGGACCGTCTATGGCATTGGAACAAGTGAACCCTATCAGCAACATTCGACAGGACCGATCATGCTTCAAATGCCCGAAACACGGCAGTATATTGTTGACGAGAGCTCGATTCAAAACATCGATCAGATGCCACCGGTTAATCTGATCATGGACACCAGCACGGATGCGTGTGATGGGTCGTCCCTGGTGGTGGCAGAAGCCGACAATCAAGTCTACCATTTAGCGACGGAATCGACCGGCGAGGTTCCGATGGACGAATACAGTGCGTCTAAGATGATGCAGTCAAACGATGTCGCTTGCGAGCAGGAAACGCAGTATGCCGAGGAATGCGAAGTAATGGAAGAGGTGATAACGGACGATTGGGTGCAATCGCAGGGTGAGGAGTGTGTGCAGGTCACGGTAGATCAGCTCGGCGCCAGTACGATCGCTGGCCAGGTGGAGGATGACATTTCCGTTCCACTCGACCAGGACGAATACACGCTGTCGAGGCCATTTCCTTGTGATTTCTGCAGCCGGAGGTTCCGGAAGAAGGCCAACTTGGAGCACCACTTGGTGGCACACTCGAACGATCGCCCATACGTGTGCAATCTGTGTGGTGCTCAGTACGGAAGGCGTATCGATCTTACAAATCACTTTAAACAGCACGCATATGCCACCAGCAATCTGGACGAAACAACAGCGCTTCGAAGCGACGATATCGACTACGATATCTTGCCCATGACACACCATAGCAAGCAGCGTGCCCATCAGTCCAGCGACGATGAAGATTTGTTCAACGAAGGGACCCGGGCCGTGAACTATAATGCGCAACCCCCAATGCAGCTAATTTCGTCGACAAACTCGACCACGACGACGTCTTCCTACGGTGGCATCAGGTTACAATATAGCAACGATCCAACGGTCGCCACAATGAGTACCCTCCTCGAAGATGGTTCCTTTTCGTACGACCATAGCCCACCAACGACGGCGGAAAGTAACCGGAGTGTTAGTTCGGCGCGCAAAGCGCGTCAACCGGATGCCACAAGCTCGCCGAGACGTCAAGCGTCCCGCGCCGGGAAATCAGTACTCTTGAAGGGAAGTCGACGGAATGCGGCACCAAATAATAGCTACATAAAAAAGGAGCCGGGAACTGTCACGAATGTGATTGGTGATGGTTTTCTGCCCCCATTGGACGAGGGAACGACACTGCAGCAGCCGGCCTTCCCGGTGGTCGATGAGCGGAAACCGTTCGTGTGCCAACAGTGTGGCGTTTCGTTTGGACGGGAAAAGGCGCTGGCTTCGCATTCCCGCGTACACGGTGGCGACATGCAGTTCCGGTGCACGACGTGTGACGAACGGTTCTGGGATCGAATGCTGCTGCAGGATCACATCCGGCAAAAGCACCCGGATGTTTTTCACCCGCAGTTTAACAGTGGTGGTGGCCCAAAGCGTTCggtcaaaacacacaaaactagTTCCTTCGTAGTTAAGGAAGAGCGAGTATCAACGTTGACGAACGATGCCCAACAGCAGTTCGTTTGTGATAGCTGCCATATGGTATTCGATCGTCCGGAGCAACTGAAGAAGCACATTCAGCTAGCACATGGTCCGACTGCGGTAGTAGTTTCCGACAACACGATCGTGAAGCGAGAGCTGTGTGAGATGATCTTGGATGCCGTGGATCAGAACATCGGGCAAGACGACATTGGTTACATGATAGATTATGAAGACCAGCAAAGTAAGAGCGATTTGGCGGCGCAGGAACAggaccagcaccagcagcctTTATTCTGCCGCCACTGTGGTGTAGCGTTCACGAAAAAGTCCGATCTACTGGCGCACACGAGCAAAATTTGCATCCGAAACGAACCGCACGAGTGTCAGCTGTGTGGTGTAAAGTTCCCCAACGAAATCGTCATCAAGCAGCACATCCAGGAGTGCCACCGGCACGAGCTCACGGACTCGTCATGTGCGATATGTGGAAAGTTGTGCAAAAATCAGAACAGCCTGATGAAGCACTCGTACGATCATTCGCGCGAACGGGTCCACTGTTGCTCCAAGTGCGGCAAAACGTTCCATCACATGGGCCGGCTCAAGCGGCACATGGGTTCGCACCGGAACAAGACGGTACGCTGCGAGGTGTGCGGTGAGGAGTTCCCGGACGGCCGGTCGCTAATGAACCACCGACATTCGCACTCCAAATCGAACAACTACCCATGCAAGGAATGCGGCAAAACGTTCGGTTCGCGATCCTCGCAGCAGATACATCTGCGGCTCCACACCGGCGAACGACCGTACGCATGTCGGTTCTGCTGGAAGGCGTTCGCGGACGGTGGGACGCTGCGGAAGCACGAACGGGTGCATACGGGCGAAAAGCCGTACGGGTGTTCTGTCTGCCCGAAGGAGTTTAATCAGCGGGTGGTCCTGCGCGAACACATTCGTGCACACCATTCGCAACCGGAACCGAAACGGGGCAGCGCGGAGCTACCGTACTACTGTCCCGTGTGCAGCAGTCTGTTTGCGACCGGGCCGGAGCTAGTGCAGCACCTCATCGAGCACAGCGATACCAACACGGCCATGAAGCGCAAACCGCCCACATACCCGCGCAAGTACAAACGCCGCCGGAAGCTGAAACCGCACGAATTGGAGCGGCTGCAGAGCGGGCGTCGAAGGCAAAAGGCGGCTTCTACGCTGGCGGCAGGCGAagaggacgacgatgatgaggaGAATGAGCAGTCGctggacgatgatgatggtggcaaTGATGATCAGCAGCGGTACGAAAGGACGATGGTACTAGAGCGTGAGGATGGGACGTTAAAAACGCCCAGTGAATTGTTCTACGAATACGGCGGCGGTGATTCTTCAAAGGCACAGAAACTTACTGTAGCTTCGTCAAAGTTTATTTCACCCTACGAACTGCTTGCGGAAGGGGCAACATCAAGTGGCAGTGGCAGGGCGCGCAAAAGAGACCTATCGACCGACAGTATGATAGATGACATTGGTATCAACCTGCTAAGCAACGGAAATTCGTACCCCCGAGCAGACTTGGCAAACCAAAGGCcatcgacgacgacaacgatgtCAAGTAAGTTTAACAATAACGACCACAAAGAAGAATCTTCCATGAAGCGCAGGGCGGGTGGTGTAAAGGGTGCAGCTACAGTGGCATCGAAATCGCCGATGGCCGTTGGTATGGCACGAATGATTCATACCGAACCGGCCAACAAACGTACTCCGGCGACGAAAGCGAATGGCGATACCAAAAGGGTTACAAGCAGAGCAAAACGAACGGTGGCGCATTCTTCTACCAAAGAGCACATACATGTGCCACCCCGGGAAATAGATGGTAACGATCTTAACCAACCGTCTGAAGTCGGCAGTGTTTCGCACGCGATGGAAGCATTCTCCGAGCTGGAACGGAATCGGTCGCATGTGCGCGGCCCCGTCCTGCCGTCGTACGTACGCGAAATACCTTCGAGTAGGATTTCGGAGAATTTCCCCCTCCTGGATGATGGCAACACGATCGACACGATGGAGGAGCAGCTGATCGAAGGTTGCTTGGACGAAGCCCGGGCTACCCTACGGCAGCGATATGGTGGAGGAAGCCGGCAGAGATTCATCTCGACGGCCAGCAGTGGAATTAGTGGGACGCGGGAGGAAGAGGACGAGCAGCTGCTGATGGAAATTTCACGCGGAGAAAAGTACACCGATCGCTTCAACAGCGACATCGTGAACGATCTAGCCGAGATCCTTCGGTCGCCACTGAAAGCAACATCGTCGTCCGCCGCAACAACGACGACCAGCGTTCCGCCGGTGGACATATTAGCATCCCCTTCGAGCCGCCATGCGGTGCTGTTGCCACCCATTGTTGTCAAGCAAGagaaaacctttttcaaaaaGGAACCCCTTGATGCTAGTGACAAGAAGAAAGCTCAAAGAAAAAAGACTGCATCGAATCGTGTGCGGAATAAAGCGAGAGTTCAAAGTACACCTTccaagcaacaacaacagcgggTGGCGGTAGCAAGTGCATCATCGACCACCCTGTCCGACCCGTATGCCAACTCGCTACTGTACAGCCACGGACGAAGACTAACCCGTCGCCAGCTCGAACGCGAGGTCAGTTTTCTCAGAGAAGCGTTTGCGCCGGGCGGATTACAAGAAACGGACACATCATCCAACGTCATTGGAAACGAAGGAACGTCCGCAGGAGTCGTAGAATCTACGTTTTCTACCGGAGGGGACAGGTTAGCGGCAGCAACTCCGGTTGTGATCAAGCAGGAGAACGTGGTTCCAGAAAAGCTTGCCGAAATGTTGCTTAACGATGGTATCGCACTTGGTGCGGGAAGTACCAGGAGTAGCTCACGTTCTTCCGACAACGATGAGAGTGTTTTAGTTGGTGCCATGGCGGAGACGACAAAGCATAAGCAGCGACAACACGGGCAGGAGGAGGGAAGTGAAGATGTTAAATTAACTACTACCAGCGGTTACCGGTGTTCAATATGTGCGGCCTACTTTGCTGATCGCTCGCAACTTATTCTCCACGTGCCGGTGCATATGTGA
Protein Sequence: MDQTYSIWPVNTGQTSGNVGSSIIAAAVPPGRQLRIVNIGSQITSDQLMGTGIVTTGGSRTVYGIGTSEPYQQHSTGPIMLQMPETRQYIVDESSIQNIDQMPPVNLIMDTSTDACDGSSLVVAEADNQVYHLATESTGEVPMDEYSASKMMQSNDVACEQETQYAEECEVMEEVITDDWVQSQGEECVQVTVDQLGASTIAGQVEDDISVPLDQDEYTLSRPFPCDFCSRRFRKKANLEHHLVAHSNDRPYVCNLCGAQYGRRIDLTNHFKQHAYATSNLDETTALRSDDIDYDILPMTHHSKQRAHQSSDDEDLFNEGTRAVNYNAQPPMQLISSTNSTTTTSSYGGIRLQYSNDPTVATMSTLLEDGSFSYDHSPPTTAESNRSVSSARKARQPDATSSPRRQASRAGKSVLLKGSRRNAAPNNSYIKKEPGTVTNVIGDGFLPPLDEGTTLQQPAFPVVDERKPFVCQQCGVSFGREKALASHSRVHGGDMQFRCTTCDERFWDRMLLQDHIRQKHPDVFHPQFNSGGGPKRSVKTHKTSSFVVKEERVSTLTNDAQQQFVCDSCHMVFDRPEQLKKHIQLAHGPTAVVVSDNTIVKRELCEMILDAVDQNIGQDDIGYMIDYEDQQSKSDLAAQEQDQHQQPLFCRHCGVAFTKKSDLLAHTSKICIRNEPHECQLCGVKFPNEIVIKQHIQECHRHELTDSSCAICGKLCKNQNSLMKHSYDHSRERVHCCSKCGKTFHHMGRLKRHMGSHRNKTVRCEVCGEEFPDGRSLMNHRHSHSKSNNYPCKECGKTFGSRSSQQIHLRLHTGERPYACRFCWKAFADGGTLRKHERVHTGEKPYGCSVCPKEFNQRVVLREHIRAHHSQPEPKRGSAELPYYCPVCSSLFATGPELVQHLIEHSDTNTAMKRKPPTYPRKYKRRRKLKPHELERLQSGRRRQKAASTLAAGEEDDDDEENEQSLDDDDGGNDDQQRYERTMVLEREDGTLKTPSELFYEYGGGDSSKAQKLTVASSKFISPYELLAEGATSSGSGRARKRDLSTDSMIDDIGINLLSNGNSYPRADLANQRPSTTTTMSSKFNNNDHKEESSMKRRAGGVKGAATVASKSPMAVGMARMIHTEPANKRTPATKANGDTKRVTSRAKRTVAHSSTKEHIHVPPREIDGNDLNQPSEVGSVSHAMEAFSELERNRSHVRGPVLPSYVREIPSSRISENFPLLDDGNTIDTMEEQLIEGCLDEARATLRQRYGGGSRQRFISTASSGISGTREEEDEQLLMEISRGEKYTDRFNSDIVNDLAEILRSPLKATSSSAATTTTSVPPVDILASPSSRHAVLLPPIVVKQEKTFFKKEPLDASDKKKAQRKKTASNRVRNKARVQSTPSKQQQQRVAVASASSTTLSDPYANSLLYSHGRRLTRRQLEREVSFLREAFAPGGLQETDTSSNVIGNEGTSAGVVESTFSTGGDRLAAATPVVIKQENVVPEKLAEMLLNDGIALGAGSTRSSSRSSDNDESVLVGAMAETTKHKQRQHGQEEGSEDVKLTTTSGYRCSICAAYFADRSQLILHVPVHM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109302;
90% Identity: iTF_00109302;
80% Identity: iTF_00109302;