Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030901.1:44103603-44105261[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3e-06 0.00024 21.5 3.8 1 23 15 37 15 37 0.98

2 12 2.3 1.8e+02 3.0 0.4 1 23 40 63 40 63 0.91

3 12 0.11 8.6 7.1 4.9 1 23 68 91 68 91 0.98

4 12 4.4e-05 0.0034 17.8 0.7 1 23 250 273 250 273 0.94

5 12 0.00014 0.011 16.2 0.9 2 23 279 300 278 300 0.96

6 12 0.00045 0.036 14.6 6.7 1 21 340 360 340 361 0.94

7 12 0.36 28 5.5 6.4 2 23 379 400 378 401 0.95

8 12 2.8e-05 0.0022 18.4 1.5 2 23 415 436 414 436 0.96

9 12 5.8e-07 4.6e-05 23.7 0.7 1 23 442 465 442 465 0.97

10 12 1e-06 8.1e-05 23.0 3.2 1 23 471 494 471 494 0.97

11 12 1.1e-06 8.7e-05 22.9 0.7 1 23 500 523 500 523 0.93

12 12 7.1e-05 0.0056 17.2 1.3 1 23 528 551 528 551 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3e-06	0.00024	21.5	3.8	1	23	15	37	15	37	0.98
2	12	2.3	1.8e+02	3.0	0.4	1	23	40	63	40	63	0.91
3	12	0.11	8.6	7.1	4.9	1	23	68	91	68	91	0.98
4	12	4.4e-05	0.0034	17.8	0.7	1	23	250	273	250	273	0.94
5	12	0.00014	0.011	16.2	0.9	2	23	279	300	278	300	0.96
6	12	0.00045	0.036	14.6	6.7	1	21	340	360	340	361	0.94
7	12	0.36	28	5.5	6.4	2	23	379	400	378	401	0.95
8	12	2.8e-05	0.0022	18.4	1.5	2	23	415	436	414	436	0.96
9	12	5.8e-07	4.6e-05	23.7	0.7	1	23	442	465	442	465	0.97
10	12	1e-06	8.1e-05	23.0	3.2	1	23	471	494	471	494	0.97
11	12	1.1e-06	8.7e-05	22.9	0.7	1	23	500	523	500	523	0.93
12	12	7.1e-05	0.0056	17.2	1.3	1	23	528	551	528	551	0.95

Sequence Information

Coding Sequence: ATGCTGCAGCATAAAACAATGTATCACGACTCGTCCGAGGCGTACATGTGCCAAATATGTGATCGCCACTTTATCACCAAAACCAACTACGAGAACCACATGCGCTACCATCAGGATTTCCTGTGCAACTTTTGCAACGCCTGCTGGGTTTCCGAGCGCACTCTACTCGATCATGTGCGCGCGGCCCACTTGGATCGTTTCTTTGTATGTCGGTTCTGTGATCGAACGGAGCGTCTTAAAAAGTGTCTGAATCGGCACCTTCGAACGTCGCACCAGCAGGAAAGCAATCCGTATTACTGTGGACACTGCGCTAAGGAGAGCATGGTGTACGACAGCTTCGAAGCGGCGATAGAGCATGTTCAAGATAAGCACACCCACGATGAAGACATCAATGATCATTCCGCTACGACGGATGGCTACGAGGGCCTGTTGAATGGATCTATTTTTTCCAAAGAACTCCCGCAGCTTGATTTCCAAGACACCGACGAATTGGTTAAGGAGCAGGAACAGTTCCTCCAAAATCTTCAGCTTACGCGAAATTATGCCAAAGAGAAAGCGTCTCCTGCGCACCAACACGAAACGCGAATCGATCGACGGGTAGTGCTGGAGGACTTTCTGGATGAAGCGTTCGAAAATGATGAGATATGGGAGAAGTATATAGAGAATGGAGAGGAGTACCTGATAGATGATTACGACATTTACCTTCAGGGAATGGATGGCACTGGCAGCCAGCCGAATCCTTGCATGTACCGCTGTCCGAAGTGCGATCGTGGCTTTCAGAAACAGATCCACTTGACGGTTCACTTGGCGGAAGAACATGACATGGCCAGTCTGGTGTGCAATGACTGTGAGGCAAGCTTTACGCGTCTGCACGCATATCGAGCGCATCGCAAGGAACACCTAAAGGAGAATGTTCGCTTCCGCGAAAGTAACATCCCGGAAATGGAGGAAGCACTCTCGTTGGTGCAAAATACCCCGGTGGACTACTCGGTGCAGGAGGAAGAAAACGGCTACCGGTTCATCTGCAAACTATGTGACCGTACCTTCCAGCGAAAGCACAATCTGGAAAAGCACCACTGCCGGTTCTACGAACAACTGGAGCAAGAGAGTGATGCAACGAGCAAGAAGCACCAACAATGTCCCCATTGCGACTTCCGATCGCATTCCGGAAAGGATCTCTATCTACACCAGAAAACACATCATAATGCTAGCAGCATCAACGCGCTTAGTCCGGAAAATATCTACTGCATGCTGTGTGATCGTCGGTTTAGTTCCACCTCCGGTTTGAAGTACCACATGAAGCGCCACACGGGCATCAAGGCATTCACGTGTATGTACTGCGGGAAAAAGTTCACGGCCAACACGAACCTTAACGCGCACATCCGAAATGTGCACAGCGAGCAGAAGGCACACCGGTGCACCGAATGTGGAGAAGCGTTCGCGACGAAGGATCATCTCAATAAGCATGAGCGCTCCCGGCACCGACAGGATCGGGCCTTCGTTTGTAGTGAATGCGGAAAGAGCTACTATCAGCGATCGCACCTGAACGAACATATAGCCGCATCCCATCGCGAGTGTCGCTATATGTGCCAGGTCTGCAACAGCTCATACGTCTCCCGAAGCTCTTTGAAACGGCACCAGCTGCTAAAGCATTCATAG
Protein Sequence: MLQHKTMYHDSSEAYMCQICDRHFITKTNYENHMRYHQDFLCNFCNACWVSERTLLDHVRAAHLDRFFVCRFCDRTERLKKCLNRHLRTSHQQESNPYYCGHCAKESMVYDSFEAAIEHVQDKHTHDEDINDHSATTDGYEGLLNGSIFSKELPQLDFQDTDELVKEQEQFLQNLQLTRNYAKEKASPAHQHETRIDRRVVLEDFLDEAFENDEIWEKYIENGEEYLIDDYDIYLQGMDGTGSQPNPCMYRCPKCDRGFQKQIHLTVHLAEEHDMASLVCNDCEASFTRLHAYRAHRKEHLKENVRFRESNIPEMEEALSLVQNTPVDYSVQEEENGYRFICKLCDRTFQRKHNLEKHHCRFYEQLEQESDATSKKHQQCPHCDFRSHSGKDLYLHQKTHHNASSINALSPENIYCMLCDRRFSSTSGLKYHMKRHTGIKAFTCMYCGKKFTANTNLNAHIRNVHSEQKAHRCTECGEAFATKDHLNKHERSRHRQDRAFVCSECGKSYYQRSHLNEHIAASHRECRYMCQVCNSSYVSRSSLKRHQLLKHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109282;
90% Identity: iTF_00109282;
80% Identity: iTF_00109282;