Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030901.1:78250878-78252924[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00043 0.034 14.7 1.6 1 23 259 281 259 281 0.98

2 11 0.013 1 10.0 0.4 1 22 285 306 285 309 0.91

3 11 1.7 1.3e+02 3.4 0.1 1 23 342 365 342 365 0.94

4 11 7.6e-05 0.006 17.1 1.4 1 23 372 394 372 394 0.98

5 11 5.5e-06 0.00043 20.7 0.6 1 23 400 422 400 422 0.97

6 11 0.00039 0.031 14.8 1.0 1 23 428 450 428 450 0.98

7 11 3.2e-07 2.5e-05 24.5 1.3 1 23 456 478 456 478 0.99

8 11 0.00096 0.075 13.6 2.7 1 23 484 506 484 506 0.98

9 11 0.00012 0.0095 16.4 0.9 3 23 514 534 513 534 0.99

10 11 1.7e-06 0.00013 22.3 0.3 1 23 540 562 540 562 0.98

11 11 2.6e-07 2e-05 24.8 0.5 1 23 568 591 568 591 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00043	0.034	14.7	1.6	1	23	259	281	259	281	0.98
2	11	0.013	1	10.0	0.4	1	22	285	306	285	309	0.91
3	11	1.7	1.3e+02	3.4	0.1	1	23	342	365	342	365	0.94
4	11	7.6e-05	0.006	17.1	1.4	1	23	372	394	372	394	0.98
5	11	5.5e-06	0.00043	20.7	0.6	1	23	400	422	400	422	0.97
6	11	0.00039	0.031	14.8	1.0	1	23	428	450	428	450	0.98
7	11	3.2e-07	2.5e-05	24.5	1.3	1	23	456	478	456	478	0.99
8	11	0.00096	0.075	13.6	2.7	1	23	484	506	484	506	0.98
9	11	0.00012	0.0095	16.4	0.9	3	23	514	534	513	534	0.99
10	11	1.7e-06	0.00013	22.3	0.3	1	23	540	562	540	562	0.98
11	11	2.6e-07	2e-05	24.8	0.5	1	23	568	591	568	591	0.97

Sequence Information

Coding Sequence: ATGTTTGCGATTGCGAGCGGCAAAAATTCGGAACAAAAGCTGCTTCTTTACGAATCGAAAGTGTGTCGACTTTGCGGGGatagaaatgaaaatggtaGACCATTGTTTCAAAGAAGTGATTCGAACGAGCAGTGTGAAACCAGCCAGCTGATTAACCGGTATTTGCCGGTGGTGGTCCAGGACGATGGTGTTTTGCCCCGTTGGATTTGCCCAGGCTGCCACATACAGCTCGAATCGACGGCACAATTTTTCGAGATGATTCTCAAGGGTCAGCAGATCATCTCGGAGTTGCTGCAGCAGGAGCGGCAAGCCCAAGAAGCGCTGCAGAACGCCTCAAAACTCGCTCGCGTCGATGATCTAGGGCAGCTGTATGACACACTGGATCAAGCAAAGTGGAACGAACTTTTTGGCAAACCGGATTTAGAAACGTCCGATAGGGATAACTTGTTGGTACCGTTGGAACTGTTCGAGCTAGAAGATTTGCTCAAGCAAGGCGATAACAACCCGGAACAACAGGCGGCTCACGTAGAGCCTGCTCAACAAGATGACGTGAAAGTAGCGAAACACTTGGAGGTTAAAGAAGAACTACCCCGGCAAGTTTCGGAAGAGATAACCGTAGAATATGAGGGTGCTGAAAAGGATTGGATCGTTAAATCAGAGATGACAAAGATGAATGCTCGTCTAATTGGTTACATTCAAAACCAGAACAAAACGGAAATCGGCAGTCTGGTGGTGATGGAAGGAGCGAGCAAAAAGAAGCGAACGAATACCAAGTTCGTCTGCGACATCTGTAGCAAGATTTTCGCGCATGAATTCCCCTACATTAAGCATCGCAAAACACACAGTATTCTGTTCGAATGTTCCGTGTGTTTGCTTAAGTTTGGGTCCAGCGTGAAATTGACGGTACACCAAAAAGAAACGCAACACATTGGGAAAGGAATTGTCGAAGGATTGCAGCTGGCAGATGATGGTGATGTATCGGTGGAAGGAGCCACCGAGCAAAACGAGCCAAAGGGCAACGCGTACGCTTGTGATAACTGTGAAGATACGTTCCCGGAGTTGACCACCGTACTTAAGCACGAAGAAACGGTACACGCAGGCGAAAACCGTTCATTCGTGTGCAGCGCTTGTAGAAAGGAGTTTCGCGAGAAGTATTTGCTCCAAAAGCACCAGGAAACGCATGTGGAAGAACGGTCACATCAGTGCGGGGTTTGTGGGGCGGCCTTCAAGACCAGTTCCTCGCTATCGAAGCACGCGCAATCGCATGCCGACAAGAAACGGTACCAGTGTACGATGTGTAGCCAGCGGTTTGCCTACAAGACCAGTCTCGACTTGCACCTGAACTGGCACAATGGTGTGAAACCGTACGAGTGCGAGTTCTGCTCGAAACGCTTCTCGCAGCGCGGCAACTTGAAGGAACATCTGCGGGTTCACTCGGGCGACAAACCGTTCAGCTGCGACGTCTGTCCGGCGACGTTTTCGACGAGCTCGCAGCATCGGTTGCACCGCAGGCGGCATGCGAACGATCGGCCACACGGTTGCGAGCTGTGCAGCAAGACGTTCATACTGCTCGAGAACTACAAAACGCACATGAGGCGCCATCGGAACGAGAAACCGTACGCCTGTGAGGAATGCACCCGTGCGTTCACCGAACGGTGGGCCCTCCGGAAGCACATCCGGACGCATACGCGCGAAAAACCTTACACCTGCAATTACTGCGCGAAACCGTTTTCGGACTCGTCTAACCTCATGCGCCACGTGACGACCATCCATGAGAAGCAGCCAAAGTCGAAGAAGAAGCAGGTGCAGCCCTCAACGCTCGCATCGGCATCGAGCGACATTCCTGATGTCAAGCCCATCGGTGGCACTCTCCCCGGGCTGGGGGTTAGCATTGACGAGACGGACACGCTGGTGTCATTGGCGGAGGATGAGATATTGGCGCTGGATACAACGGTCTACATGGCCGATCATTAA
Protein Sequence: MFAIASGKNSEQKLLLYESKVCRLCGDRNENGRPLFQRSDSNEQCETSQLINRYLPVVVQDDGVLPRWICPGCHIQLESTAQFFEMILKGQQIISELLQQERQAQEALQNASKLARVDDLGQLYDTLDQAKWNELFGKPDLETSDRDNLLVPLELFELEDLLKQGDNNPEQQAAHVEPAQQDDVKVAKHLEVKEELPRQVSEEITVEYEGAEKDWIVKSEMTKMNARLIGYIQNQNKTEIGSLVVMEGASKKKRTNTKFVCDICSKIFAHEFPYIKHRKTHSILFECSVCLLKFGSSVKLTVHQKETQHIGKGIVEGLQLADDGDVSVEGATEQNEPKGNAYACDNCEDTFPELTTVLKHEETVHAGENRSFVCSACRKEFREKYLLQKHQETHVEERSHQCGVCGAAFKTSSSLSKHAQSHADKKRYQCTMCSQRFAYKTSLDLHLNWHNGVKPYECEFCSKRFSQRGNLKEHLRVHSGDKPFSCDVCPATFSTSSQHRLHRRRHANDRPHGCELCSKTFILLENYKTHMRRHRNEKPYACEECTRAFTERWALRKHIRTHTREKPYTCNYCAKPFSDSSNLMRHVTTIHEKQPKSKKKQVQPSTLASASSDIPDVKPIGGTLPGLGVSIDETDTLVSLAEDEILALDTTVYMADH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107827;
90% Identity: iTF_00109298;
80% Identity: iTF_00109298;