Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030901.1:96695594-96698682[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00058 0.046 14.3 6.4 1 23 228 250 228 250 0.98

2 14 2.8e-07 2.2e-05 24.8 0.4 1 23 286 308 286 308 0.98

3 14 4.2e-07 3.3e-05 24.2 0.7 1 23 314 336 314 336 0.98

4 14 9.5e-07 7.5e-05 23.1 3.5 1 23 342 364 342 364 0.98

5 14 0.00017 0.013 16.0 0.6 1 19 370 388 370 391 0.95

6 14 1.5e-05 0.0012 19.3 0.8 1 23 397 419 397 419 0.98

7 14 1.6e-07 1.3e-05 25.5 1.1 1 23 428 450 428 450 0.99

8 14 4e-07 3.2e-05 24.2 0.6 1 23 456 478 456 478 0.99

9 14 0.0012 0.095 13.3 1.0 1 19 485 503 485 504 0.95

10 14 0.00022 0.017 15.6 1.1 1 23 597 619 597 619 0.98

11 14 1e-05 0.00079 19.8 0.6 3 23 675 695 673 695 0.96

12 14 3.2e-06 0.00025 21.4 3.3 1 23 701 723 701 723 0.99

13 14 5.5e-05 0.0044 17.5 2.7 1 23 731 753 731 753 0.98

14 14 5.2e-08 4.1e-06 27.0 1.3 1 23 759 781 759 781 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00058	0.046	14.3	6.4	1	23	228	250	228	250	0.98
2	14	2.8e-07	2.2e-05	24.8	0.4	1	23	286	308	286	308	0.98
3	14	4.2e-07	3.3e-05	24.2	0.7	1	23	314	336	314	336	0.98
4	14	9.5e-07	7.5e-05	23.1	3.5	1	23	342	364	342	364	0.98
5	14	0.00017	0.013	16.0	0.6	1	19	370	388	370	391	0.95
6	14	1.5e-05	0.0012	19.3	0.8	1	23	397	419	397	419	0.98
7	14	1.6e-07	1.3e-05	25.5	1.1	1	23	428	450	428	450	0.99
8	14	4e-07	3.2e-05	24.2	0.6	1	23	456	478	456	478	0.99
9	14	0.0012	0.095	13.3	1.0	1	19	485	503	485	504	0.95
10	14	0.00022	0.017	15.6	1.1	1	23	597	619	597	619	0.98
11	14	1e-05	0.00079	19.8	0.6	3	23	675	695	673	695	0.96
12	14	3.2e-06	0.00025	21.4	3.3	1	23	701	723	701	723	0.99
13	14	5.5e-05	0.0044	17.5	2.7	1	23	731	753	731	753	0.98
14	14	5.2e-08	4.1e-06	27.0	1.3	1	23	759	781	759	781	0.98

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATCgatcaataaaaataagatATTAACCCAAAGATACGGAAATAGTAACAACGATATTTGCAgattgtgtttgaaaaatgagcCACATATGGAGCCGTTGTTTTACACCAATCTGTTTCCTAATATTTTGCTCACGAAAAAAATATACGATTGCACCTCCATTCAGaTCATTTACGATCGTAACCTGCCGATGTTCGTATGCAAACTGTGCGCCAACAAGCTGGACGAGTATGTGCGATTTCGGGAGCGGTGCGTGGCGAACGACGAATTCCTGCGGAACGCCTTGGCGGCCTTCGACATGGGAAATGGTGCTGGAAATTGTTCGGGCATCATTAAAAAGGACCCGGATGGTAGTCCCCCGCCACCGACCAAGCTGGCGCAATGTCTCGGTGTAACGCCAATCGAACTGAACCGTGCTCTAGTGGCTGCAGCGGCAGCCGCCACAGATCACCAAACGGCAAAGCGAGAACCGTTGGATTTAGAAGACGACGATGGGTCGCAGAATGGACGGATGTATGAACATGGATCGCAGACCAGTTCACCGGATCGCAGCAGCGACTTGGTGGGAGATTTTACACACGGGAAAATGCACGATGCGATATTTAGGAGTGCAAACCTGGTCGGAATTCCGAGTGGAATTAGTGAACCTCAGCATGAATCGCCCCCGTATGTGTGCGAAATTTGCTCGAAATCGTTTAAAATACGGCACCATCTTCTTGTGCACCGGCACACGCACGTGGATAGCCATAACGAATTGCCAATCAGCATGTTGAACGGTGGAGTTGGTGGTGGAGTTTCAGGTGGTGACGGAGGGGGAGCTACAGGAACCGGGAAACAATCGTACAGCTGCCCGAAATGCACCAAAGTATTCGTTAACAAGGGAAACCTGCTCAATCACCTCGAGACGCATACGAACGAGAAGAACTATGCATGTGAAATTTGTTCGAAGACGTTCAAGTACAATGTGCAGCTACGGTTGCATATGCGCATTCACACCGGAGAACGACCGCACAAGTGCGAAATCTGCAATCGCGGATTTTCCCAGCTGTCCAACCTAAGGTCCCACCGGAAAACCCACTCCAAAGTTAAACCCTACAAGTGCCATTTATGCTTAAAAAGTTTCACCGTGCTCGACAACCTTACGGCGCACAGTGCCAAATGTCTGAAAGACAAATTCCGATGTTCACTCTGCTCGAAGTCGTTCGCCAAGGAAGGCAACCTGCTGACCCACCTGCAGTCGCACAGCGAGGGCGTCGTGGAAAAGATGTTCAAGTGCGAGATGTGCCCGAAGAGCTTCAAGAACAAGGAAGACTGGAAGCGCCATGTGCGCGTGCATACGGGCGAAAAGCCGTACACGTGCGACATCTGCTCGAAGGGGTTCGCTCAGAAGGCCAATCTTCTATCGCACCAGAAGACGCACCTAAAACCGAACGTTATCTTCAAATGCGACCGTTGCGATCGTACGTTCCGGACGCAAAAGGTACTGGAAATGCACTTTCCAAAGTGCGGCGTTGTAGGTGCCGGTTTGGCGGTGTCATCAAGCCCCGTGACACCACGGTCCGAGTCGACACCGGTTGGTTCGCCGAGTCCGGTGACGACTGGGACGCCGGCTACCACCGCAACTACACCGACGCTTTCGGAGGCTCTTTCCGATCTGCTGCGATATGAAATAGCACTGCGGGCACCGCTGGAGCTTCAACAGATGCTGCTTGGACACATGGATCGCAAGAAGCCAAACGTGACCGGTAGCGGGGGCAAGCCCACGGGACGTCGATACCGGTGTGACGTGTGTTTCAAGGGTTATTCACAGTATCCATCCTTGATAAAGCACCGAAAACTGCACTTCAAGGTACCTCCGCTAGTGAAGGTTCTTGGCGCCAAGGCAAAGAACCCACCGGATCATAACGACAGCGTCACCTGTGACGATGGTGAGGAGATGCAGGCACAGGCGGTAGGACCGCTGGTATCAGCGCCGGACCTTGCGTGTGACCCGGAGCGACCGTACGGCTGTGATATTTGTGGTAAGAACTTTAAATACAATCGGAACCTGAAGGTTCACGCCAAGCTGCACATCAGGGCAAACCGTTTTAAGTGTGACAAGTGTACCACCACCTTTGAACAGGCGGAAGATTTGAAGCACCATCTGCGCACCCACCCGATCGCTGCCGAGAGGATCTTCAGCTGCGAGTACTGCTTGAACCGGTTCCGCTCGAACGAGGACCTGAAGCGCCACCGGCGGTCGCACACCGGCGAGCGGCCTTTCCGGTGCACACGTTGCCCGAAGGCATTCACGCAGCAGTCCAACCTGCGGGCCCACACGAGGATTCACGAACGACCGCCGCCGACCGCATGCAGGGCCCTCCAGCCGGAAGGTCTACTCTACCCGGGACGGATGCAGGATCTGGGATGGAAGCAGGAATCGTTTCCCCAGGAATGCCCGCGGAACCAGCAAGAGAACCTCAGAGATGTGTAA
Protein Sequence: MAEDLSINKNKILTQRYGNSNNDICRLCLKNEPHMEPLFYTNLFPNILLTKKIYDCTSIQIIYDRNLPMFVCKLCANKLDEYVRFRERCVANDEFLRNALAAFDMGNGAGNCSGIIKKDPDGSPPPPTKLAQCLGVTPIELNRALVAAAAAATDHQTAKREPLDLEDDDGSQNGRMYEHGSQTSSPDRSSDLVGDFTHGKMHDAIFRSANLVGIPSGISEPQHESPPYVCEICSKSFKIRHHLLVHRHTHVDSHNELPISMLNGGVGGGVSGGDGGGATGTGKQSYSCPKCTKVFVNKGNLLNHLETHTNEKNYACEICSKTFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTVLDNLTAHSAKCLKDKFRCSLCSKSFAKEGNLLTHLQSHSEGVVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHQKTHLKPNVIFKCDRCDRTFRTQKVLEMHFPKCGVVGAGLAVSSSPVTPRSESTPVGSPSPVTTGTPATTATTPTLSEALSDLLRYEIALRAPLELQQMLLGHMDRKKPNVTGSGGKPTGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLGAKAKNPPDHNDSVTCDDGEEMQAQAVGPLVSAPDLACDPERPYGCDICGKNFKYNRNLKVHAKLHIRANRFKCDKCTTTFEQAEDLKHHLRTHPIAAERIFSCEYCLNRFRSNEDLKRHRRSHTGERPFRCTRCPKAFTQQSNLRAHTRIHERPPPTACRALQPEGLLYPGRMQDLGWKQESFPQECPRNQQENLRDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109285;
90% Identity: iTF_00109285;
80% Identity: iTF_00109285;