Acou012485.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles coustani
Gene Symbol
-
Assembly
GCA_943734705.2
Location
OX030901.1:56815749-56818480[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.7e-06 0.00037 20.9 1.4 1 23 353 375 353 375 0.98
2 13 1.7e-06 0.00013 22.3 1.1 1 23 381 403 381 403 0.97
3 13 5.7e-06 0.00045 20.6 0.4 1 23 409 431 409 431 0.98
4 13 0.00017 0.013 16.0 3.9 1 23 437 459 437 459 0.97
5 13 6.4e-07 5e-05 23.6 0.1 1 23 465 487 465 487 0.98
6 13 1.7e-06 0.00014 22.2 1.3 1 23 493 516 493 516 0.96
7 13 5.2e-06 0.00041 20.8 2.2 1 23 522 544 522 544 0.98
8 13 2.4e-07 1.9e-05 24.9 0.9 3 23 552 572 550 572 0.98
9 13 4.4e-06 0.00035 21.0 1.2 1 23 578 601 578 601 0.97
10 13 6.9e-05 0.0054 17.2 1.9 1 23 607 629 607 629 0.98
11 13 1.8e-07 1.4e-05 25.3 0.4 1 23 635 657 635 657 0.97
12 13 6.3e-07 4.9e-05 23.6 2.4 1 23 663 685 663 685 0.95
13 13 0.00078 0.061 13.9 0.6 2 23 716 738 715 738 0.95

Sequence Information

Coding Sequence
ATGGTCCATTTCTGCAAATTGTGCCAGTTGCTGCACAAAAACATGGACTTCATCCAGTGCGATGAGTCCAATGTTTGGCTTCTGGAAGCTGTATTTGCCGTAAAGATAACTCCACTTGATGGACGTGTCGAACCAATCTGCCGGAAATGCATACGCAAGTATAACAAAGTCATGAAGGATCTAAAAAAATCGAACGGTGGATTTCCCGTTTCTCGGCAGACGCTGGCGGAACATACCAAAATTGCGAATGGCGATGTGGAATCTCTTGCCATAAATTCCGGCGAGCAGCAACAATTTCAGCAGGCCGCATTGCAATCACCGTTACTGCCATCGCTGACACTGAACCAAGGTAGCCGCTCGTCGGAATCCCATCCGTATTTGATGGACGACGAAAGTAAGGAACTGATGTTTACCGGTGCTTCCGATCCGGTGAATGGTTGCCAGAATGGAAGCAATGGGTTTGCATTGAACATTAGCGGTGATGCGGCAACAGTGTACCGGACGTCGTTGGGTGACACGCAGGAATCTTCTGACGACGACAGCTCCGATGGGAAGAGCAGTGTCCCAGATGAAGACGATGAAGAAGATGATAGTACCGAGGAATCCAgtgaagacgacgacgacgatgatgatgacgatgagtGCTGCACTGATGATACTGACGATACGAGTTCGAGTTGTaccagcagcagtagtagcgGAGGTAGTTCCTCCGAAACCGGTGCCAGCCTCCGGTTGGAAGAACATATCGAACCAAACGCGCAGGAGTCTACAGTGCTTTATAGTTCATATTTGCAGGCACCGTTGATGCAAAATCTTCCGGAAGGAAGTCTGCTGCAGTGTAACGGTGATGGGCTTGTTGTCGAAGACCAAATACCGCCGGATAAGACAGGTGATGATTTAGAACCGTTGCAGCTCGAAGAACCACTAGCGCAAATAGAGAACGACGTTGACAAGAACGGAGACAAACCTGAAGAAGCGATTAGTGAAGAAAACTCCAAAAAGTCTCGGAAACGTAAAAAACGACCTAGTGGGGCGGCAGTTCAGACAAAAAACTACATATGCAATGTGTGCCAAAAGCGTTTTTCCAAGGCAATTTATCTGAAGGTGCACTATCGGACGCACACCGGAGAAAAGCCGTACGCGTGTGATATCTGTTTCAAAAGTTTTACCCAAGCGTCCAGCTTGAACACGCACAAACGTTTGCATTTCAACGTGAAACCGTTCGTTTGTGAGATTTGTAACCAACAGTATACGAGCGCAGGGAACTACAAGGTGCATCTGCGAACGCACACGCAGGAAAAACCGTACGCCTGTAGCTACTGCGACAAACGGTTCAGCCAGCATTCGAGCAAGAAAATGCACGAACGGGTGCACAGTCAGGAAAAGCCGTACCCGTGCCAGGTGTGTCTCAAGGCGTTCAGCAACGTGAGCAATCTAACGGTGCATATGCGCATCCACCAGGGTCTTAAGCCATACAAGTGTGATAAATGCGATAAGAGCTTTGCCCAGTCGCAGACCCTAAAGACGCACTACATCTCAGCACACACCGACGTCCGGCCCTTTCAGTGTGACCTGTGCCCAAAATCGTATGCGACACTATCGAATTTAaacaaccacaaacacacgcacatggAGGAGAAACCGTTCGGTTGCGAAGAGTGCGGAAAGCGGTTCACACAAAAGTCCTCGTTGAAGACGCATATCCTTTCGCATAGCACAGAACGTCCATTCCCCTGTACCGAATGTACCAAGTCGTTCAACTCGCAGGCCATGTTGAATACGCACCGCCGTAACATGCACTGTACAGTGCGTCCGTTCCAGTGTACCCAGTGCACTAAATCGTACGCACAGGAGACGCGGTTACGACAGCATATGCTGAGCCATGCAGAGATAAAACCGCATCCGTGTGTAGAGTGTGGCAAAACGTTCGCGACTGCAACGAACCTACGCATACACCAACGGGTGCATTCGGGCGAAAAGCCCTATTCTTGTCCAACGTGCGGGAAATGTTTCTCGCAGAGATCATCACTCCGAACACATGAAATTCTTCATTTGCCCGTTGAAATGGGCCCCGATTCGGCGGCCTCCAGTGGAGGTGCTGTTCCGGgcggggggaagaaaaagcgCAAGTCAAAAAACCTCGAATGTGATCAATGCGGAAAGCAGTTTACGGTGCGGGGACGGTATTACAACCACATGAAACAGGTGCACCAAAAGGACGTCCAGGGGGAAGATGGGCAGGATTTAGGAAATTTAAATCACcacaacgacgacaacgagaCAAACAATCAATGTGTAAAAGGGGACGAGGCCATGGGAGAAAATGAACACGATCTGGATAGAAAGCATACAATTAGTAAGGAAACTATTGATGGTATTCTTATAGCTTCCGATTCCGCTGTTTCATATGGCATCGATATGCCCGAGGGAGGAGGTTCTCATGAACATACCCAAGATacagacgacgacgaggaagacgatgacgatgacgatgaagatgaagaagaagatgaggAGGAAgctgatgaagaagaagaggatgaagatgaagaaggtgATGATTTGTTGGACAATTCTAGTGTGCCCTTGCAGGAACAGTTCCATTATGGACAGTTAATGTccgaacaaaattaa
Protein Sequence
MVHFCKLCQLLHKNMDFIQCDESNVWLLEAVFAVKITPLDGRVEPICRKCIRKYNKVMKDLKKSNGGFPVSRQTLAEHTKIANGDVESLAINSGEQQQFQQAALQSPLLPSLTLNQGSRSSESHPYLMDDESKELMFTGASDPVNGCQNGSNGFALNISGDAATVYRTSLGDTQESSDDDSSDGKSSVPDEDDEEDDSTEESSEDDDDDDDDDECCTDDTDDTSSSCTSSSSSGGSSSETGASLRLEEHIEPNAQESTVLYSSYLQAPLMQNLPEGSLLQCNGDGLVVEDQIPPDKTGDDLEPLQLEEPLAQIENDVDKNGDKPEEAISEENSKKSRKRKKRPSGAAVQTKNYICNVCQKRFSKAIYLKVHYRTHTGEKPYACDICFKSFTQASSLNTHKRLHFNVKPFVCEICNQQYTSAGNYKVHLRTHTQEKPYACSYCDKRFSQHSSKKMHERVHSQEKPYPCQVCLKAFSNVSNLTVHMRIHQGLKPYKCDKCDKSFAQSQTLKTHYISAHTDVRPFQCDLCPKSYATLSNLNNHKHTHMEEKPFGCEECGKRFTQKSSLKTHILSHSTERPFPCTECTKSFNSQAMLNTHRRNMHCTVRPFQCTQCTKSYAQETRLRQHMLSHAEIKPHPCVECGKTFATATNLRIHQRVHSGEKPYSCPTCGKCFSQRSSLRTHEILHLPVEMGPDSAASSGGAVPGGGKKKRKSKNLECDQCGKQFTVRGRYYNHMKQVHQKDVQGEDGQDLGNLNHHNDDNETNNQCVKGDEAMGENEHDLDRKHTISKETIDGILIASDSAVSYGIDMPEGGGSHEHTQDTDDDEEDDDDDDEDEEEDEEEADEEEEDEDEEGDDLLDNSSVPLQEQFHYGQLMSEQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00109284; iTF_00107816;
90% Identity
iTF_00107816;
80% Identity
iTF_00109284;