Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:92089999-92092953[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00079 0.062 13.9 0.1 2 23 118 139 117 139 0.97

2 17 4e-05 0.0031 18.0 4.4 1 23 219 241 219 241 0.97

3 17 0.00029 0.023 15.2 0.2 2 23 316 337 315 337 0.97

4 17 4e-05 0.0031 18.0 4.4 1 23 419 441 419 441 0.97

5 17 6.6e-06 0.00052 20.4 1.5 3 23 504 524 503 524 0.98

6 17 0.15 12 6.7 0.7 1 16 588 600 588 607 0.73

7 17 4.4e-06 0.00035 21.0 2.0 1 23 670 692 670 692 0.97

8 17 6.6e-08 5.2e-06 26.7 0.6 1 23 698 720 698 720 0.99

9 17 1.2e-08 9.6e-07 29.0 1.0 1 23 726 748 726 748 0.98

10 17 8.4e-09 6.6e-07 29.5 1.8 1 23 754 776 754 776 0.98

11 17 0.00032 0.025 15.1 0.3 2 23 779 800 778 800 0.95

12 17 0.00033 0.026 15.1 0.4 1 23 806 829 806 829 0.97

13 17 2.7e-08 2.1e-06 27.9 4.7 1 23 835 857 835 857 0.99

14 17 0.00033 0.026 15.1 1.5 1 23 863 885 863 885 0.98

15 17 3.8e-08 3e-06 27.5 1.8 1 23 891 913 891 913 0.99

16 17 1.3e-06 0.0001 22.6 3.6 1 23 919 941 919 941 0.99

17 17 3.4e-08 2.7e-06 27.6 2.0 1 23 947 969 947 969 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00079	0.062	13.9	0.1	2	23	118	139	117	139	0.97
2	17	4e-05	0.0031	18.0	4.4	1	23	219	241	219	241	0.97
3	17	0.00029	0.023	15.2	0.2	2	23	316	337	315	337	0.97
4	17	4e-05	0.0031	18.0	4.4	1	23	419	441	419	441	0.97
5	17	6.6e-06	0.00052	20.4	1.5	3	23	504	524	503	524	0.98
6	17	0.15	12	6.7	0.7	1	16	588	600	588	607	0.73
7	17	4.4e-06	0.00035	21.0	2.0	1	23	670	692	670	692	0.97
8	17	6.6e-08	5.2e-06	26.7	0.6	1	23	698	720	698	720	0.99
9	17	1.2e-08	9.6e-07	29.0	1.0	1	23	726	748	726	748	0.98
10	17	8.4e-09	6.6e-07	29.5	1.8	1	23	754	776	754	776	0.98
11	17	0.00032	0.025	15.1	0.3	2	23	779	800	778	800	0.95
12	17	0.00033	0.026	15.1	0.4	1	23	806	829	806	829	0.97
13	17	2.7e-08	2.1e-06	27.9	4.7	1	23	835	857	835	857	0.99
14	17	0.00033	0.026	15.1	1.5	1	23	863	885	863	885	0.98
15	17	3.8e-08	3e-06	27.5	1.8	1	23	891	913	891	913	0.99
16	17	1.3e-06	0.0001	22.6	3.6	1	23	919	941	919	941	0.99
17	17	3.4e-08	2.7e-06	27.6	2.0	1	23	947	969	947	969	0.98

Sequence Information

Coding Sequence: ATGCTCGGTAAATATGCTGACGCGAGTTCCAGCTCGATGATAAACCTGGAAAATGGGCTCCGCAACCGTGTGCTGTACCATCAGAACATGATGGGTATGAATCTGATGGCCGAATTTTACCACAACCCTCTAATGAATTCCTCCGGAAGCAACGGTGCCGGTGGTAGCGACGCTGTTGGAGCCGGCTCAATGCTATCGCCATCGCAAAAGATGCTCAACATTCTGTCAGTTAGCGCTGGAAGCAATCTGCAACCGCATCACACCGGAAATAGTTCCGTAGTGTCAACAGTGCCGGTAGGTTCTGCATCGACGGCGTCAAGCGGTTCATCGCAGCAATCGTTGGTACAGTTGCAATGTCAACTTTGCCAAAAGTACTTTATTTCCGGGGCGGCGCTCGCGCAGCATATTAAAACACACGAAAATGATTACCTTGCGCGGGAAGAATCCGGTCCCAGCGGCGGTTACAGTCAACAGCAGTCGATAACGTCCGCTCCATCGCTTGTAACGACGGTGGCTTCGAGTAGCAAAACTAGTTCACCATTGCTTGCACAGCAAAGCATCAAGAGTGAGTATATTGTACGTAGTACGTCGTCTTCGTCTGTGCCCTTGCCAGGTGGGAACCAATTTCCTACAGCATACGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTCATGACGATGATGAACCTTAACCTGCATATGAAAATCCACGAAGAGTTCAAACCGGCTGTGGTGTCTTCTCTTGCGAATCCGTCCGGTGGTAGCAGCGGAACCGTAACGTCACAGGCGCAAAAGCCGCTCAACATTATGTCGCACCATACCAGCGCGGGAAGTACTCCACAACTGCAGCACTCCGTAAATGGTTCGGTTGTGACGACAATAGCACTAGGCGCCGTGCCGTCGACATCGAGTGGTACATCGCAGCAAGCGTTGCAATGTCAAATTTGTCAAAAGTACTTCATTTCCGGCACTGCACTGGCGCAGCATATTAAAACACACGATAATGACTACCTGGCGCGGGAAGAATCCGGTCCCGGTGGCAGCTATAGTCAGCAGCAATCGTTAACGTCGGCACCCTCGCTAGCAACGGCAGTGGCATCGAGCAGTAAAACTAGTCCCCCACTGCTTGCACAGCAGAGCATAAAAAGTGAGTACATTGTACGAAGTGGTGCATCATCTTCTTCTACCGTGCCCGTGCCAGGTGGGAACCAATTCGCTCCCGCGTATGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTTATGACGATGATGAACCTTAACCTGCATATGAAAATTCACGAAGAGTTGAAACAAACAGCTGCAACCCACGTCTACACCCATGCCCCGACCCTTGGCGCTACAAGTGCAGGGACATCGTCTAACGAttatcatcaccaccatcagcagcaccaCAACAATTATCACAACAACCCGCAGCAGCACATTTCGATGGTGGCAGCGACAACGATTGGGACGGATGGTGCGTGCCAGATTTGCCATAAAACATTCAGCACGGTCGAGCAATTTACGGCGCACATGAAGATTCACGAAAACGAGTTTAGGAATCGTGCGCTCTATCACTCCGGTAGCTCCAATACCATCGGTCCCGGTGTAGAAGGAAGTGTAGTTGTCCAGAGTACGCCAACGACGACAGATTCTTTCTATTCGTCCACTCAATCACAGCCGATCCTCGCACAACAACAAACGACTGCACCACAGTTTGATGCCATGAAAGGATATCGATGTCCCATTTGTCACAAAATGTCCAGCAACATCATCGAACACATCAAACAACACGAAGGGCAGCTAATGTTAGGTGAAGGGGCTGCAAGTAGTCGAAGTGGAACGACACCACCCACGCCGGATGTGACATCGCCTGCGCCGGAAGGGTTGTCGTACCATCCGATGAATGAAGATACGCAATCATCGCTCGAAGGAGACGACAGCGAAGGCCAGACGGGAGAAGGTGCCGATGTTCGAAAGCACGAGTGCCTACTCTGCCACAAAAAGTTCTCGAGCTCGGGAAATTTAGCCATTCACATACGGGTGCACTCGGGCGAGAAACCGTTCAAATGTAGCGTCTGCGGGAAGGGTTTCATCCAGTCGAACAACCTGGCGACGCATATGAAAACGCACACCGGCGAAAAGCCGTACGCGTGCACGATTtgcgggaaaaacttttcgcaATCGAACAACCTGAAAACGCACATCCGGACGCACACCGGCGAAAAGCCTTACGCGTGTACCATCTGCGGGAAGCGGTTCAACCAGAAGAACAATTTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGCGTGCAGTTCATGCATCCGTCCGACCTGGCCAATCACATGAAGTTTCACAATGACGAAAAGCCGTACATCTGCTCGGTTTGCAACAAGGTGTACCTCAACCTGGACGAGCTTACCGAGCACATGAAGAAGACCCACAACCAGGTTAAGCCGTACCGGTGCCACATCTGCGACAAAACGTTCACCCAATCGAATAACCTGAAGACGCACATCAAAACGCACATCTTTCAGGATCCGTTCAAATGTCAGATGTGTTCGCGCTCCTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTCCACACGGCCGACAAACCGTACGAGTGTACGTACTGCGGGAAGCGGTTCATTCAGTCCAACAACCTGAAGACGCACGTCCGGACGCATACGGGCGAAAAGCCGTACCGTTGTACAATCTGCGCAAAGCACTTCAACCAGAAAAACAATCTCAATACACACATGCGCATCCATACCGGCGAAAAGCCCTTCGAGTGCACCATCTGCGATAAGCGGTTTAACCAGTCGAACAATTTGAACAAGCACATCAAAACGCATGGTCAAGAAAAGGacacgcagcagcagcagccacagcACGCAAGTTGA
Protein Sequence: MLGKYADASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPLMNSSGSNGAGGSDAVGAGSMLSPSQKMLNILSVSAGSNLQPHHTGNSSVVSTVPVGSASTASSGSSQQSLVQLQCQLCQKYFISGAALAQHIKTHENDYLAREESGPSGGYSQQQSITSAPSLVTTVASSSKTSSPLLAQQSIKSEYIVRSTSSSSVPLPGGNQFPTAYGITKQFDCHICHKSFMTMMNLNLHMKIHEEFKPAVVSSLANPSGGSSGTVTSQAQKPLNIMSHHTSAGSTPQLQHSVNGSVVTTIALGAVPSTSSGTSQQALQCQICQKYFISGTALAQHIKTHDNDYLAREESGPGGSYSQQQSLTSAPSLATAVASSSKTSPPLLAQQSIKSEYIVRSGASSSSTVPVPGGNQFAPAYGITKQFDCHICHKSFMTMMNLNLHMKIHEELKQTAATHVYTHAPTLGATSAGTSSNDYHHHHQQHHNNYHNNPQQHISMVAATTIGTDGACQICHKTFSTVEQFTAHMKIHENEFRNRALYHSGSSNTIGPGVEGSVVVQSTPTTTDSFYSSTQSQPILAQQQTTAPQFDAMKGYRCPICHKMSSNIIEHIKQHEGQLMLGEGAASSRSGTTPPTPDVTSPAPEGLSYHPMNEDTQSSLEGDDSEGQTGEGADVRKHECLLCHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPFKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDTQQQQPQHAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108044;
90% Identity: iTF_00108044;
80% Identity: iTF_00109283;