Basic Information

Insect: Anopheles coluzzii
Gene Symbol: BCL11B
Assembly: GCA_016097175.1
Location: CM027928.1:24707050-24731298[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 7.7 4e+02 1.5 0.1 2 11 32 41 31 44 0.86

2 6 0.57 30 5.0 2.6 1 23 234 257 234 257 0.95

3 6 9.2e-08 4.8e-06 26.4 2.5 1 23 695 717 695 717 0.99

4 6 0.017 0.89 9.8 0.8 1 23 723 746 723 746 0.97

5 6 9.6e-07 5e-05 23.2 3.2 2 23 1004 1025 1003 1025 0.97

6 6 1.3e-05 0.00066 19.7 3.3 1 23 1031 1053 1031 1053 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	7.7	4e+02	1.5	0.1	2	11	32	41	31	44	0.86
2	6	0.57	30	5.0	2.6	1	23	234	257	234	257	0.95
3	6	9.2e-08	4.8e-06	26.4	2.5	1	23	695	717	695	717	0.99
4	6	0.017	0.89	9.8	0.8	1	23	723	746	723	746	0.97
5	6	9.6e-07	5e-05	23.2	3.2	2	23	1004	1025	1003	1025	0.97
6	6	1.3e-05	0.00066	19.7	3.3	1	23	1031	1053	1031	1053	0.99

Sequence Information

Coding Sequence: ATGCTGTCCACCAGCGAAGATGCCGGATTCTACTCGCACAACCGTGATCATTCCGAAGCGGGAGAATCGGACGGCACCACGCAGGACATCCTTACATGCGGGTCGTGCCAGAAAACGTTCGCCCTCTCCGACATCGTGCGCTTCATCCAGCACAAAGTGTTCCAGTGCAACAAGGAAAACTATGGCCAGTGCTTCACGCAAGCGGGCGGCGGTACCGATCGTGACTCGGACGACGGCCGGCGATTGCTGCTGACGGGCAACACGAGCAGCATCGCGACGAGACGTGCCTCCATGCCGAACGTGTCCTGCCGGGCGGGGAAGCAGACCATCACCACCGCCAGCGCGACGTACGACGACCGGGTCCACACACCGCCCCCGACCAGCCCGGCCGAGCTGCTGCGGGACGGTGCCTCCAGCACACCGAAACACCCAGGCGATGAACCAGAGAACGCGTCCACCCATTGCCCGTCGCGGGGAGCGAGCCCGCTCGGCTGCACCCTCGACGACGACCACCGCGACCAGAAACCGTCCGTCCGTGCGATCGAAATCAAGCAGGAGCGCATGGACATCGATCCGGCGTCGTGCGGCGAGGAGGAGTTCGTCAGCGTCCGGAAGCAACAGCCCCAGACGGTCGCCACCGCCCACCGGAACGGCTCGCACGATGCGTCCGAGTCGCCGAACCATACCGAACCAAGCAACTACGTCTGCTCTACGTGCAAAACGAAGTACCATTCGGCCTGGCGGTTGGTCCAGCACGTCCAGCACGCGCACGGTGTGAAGATTTACGTCGAATCGTTGGCCAGCACGGGCAGCCAGGACGGGGATGGCGCCGCACCGACCGAAGAATCGGACGCACCGGAATCGGCCGCCGCATCGGAGGCGGCTAACAACGGCCCATCGACCGGGGAAGCCGTTCCGGCGGCACAGAAGCGAACGGACGAGCAGCCGGCACGAGCCCGCACGCCACGGTCCCGCTCTGCCAGCCGCAGTCCGAAAGCCGTATCCATCGAGCGGGAGCAACCGATCCGTTCGCCGGCCCCGAAAGACCGGAGCAATGGGCTGGAGGTGCCCTCGAAAGCGGCCAGTGAAAATGGCAGATCCGGCGAGTCGGACGATGAGCTGGAGGTGCGCACGAAGCGACCGAAGCTGACCAGCAGCAGTTCGAACGGAAGCCACGCCACGGTCAACCACACCGAGGAGGTAGCGCTGGCCCTTACCAGCCCGCAGCCACTCACTCAGACCGCCGCGACGACCACGACCCAGCAGCGACAATCGAGCACACCGCAGCCGCTGACCGTCTCCTCGGTCCAGTCACCGTCCCGGCCGCAACATTCGCCTCCCGCGGGCAGCGGGACCATCGCAGCGCCCTCCCTAGCACCGGCCCGCAGCGAATCCACCCAGAGCCTTCCGCCGCCGTCGCTGCGGCCGCACCATTCGCTGCTGCCGCCGCCCGAGCTGCACCAGAACCCGTTCGGGCTGCTGCGCATGCCACCGCACCACCCGCACAGCCCGCTGTTCGGCCGCACGCATCACGACTTCCGCATGGAGCACCTGATGTCGGAACAGTTCCGCAGCCACGGGCTCAACCTGGCGGCGGCTGCCGTTGCCGCCGCGAACCAGCTCAAATCGCACGGCCAGCAGTTCAACCCGGCCACCGGTGCGACCGCATCGGAGCGGCCGCCGTCCGCCGGTGCGGCCACCTCCGCCCTTACCCTGACACCCGGCGGAGGCGGAGCCGGTGTTGTTGGCGGGCTCGAGCCACACATGGACTACTACTCGCAGCGCTTGCGGCAGCTCGCCGGCACGACCAGCCCCGGGGCGAACCTAACGTCCGCCTCGTCCAACTCACCCAGCCCGCGCAAGCAGCCCCACTCGCCCTCACACTTTGCCAGCCCGTCGCCCTCCCATCAGCTGCCACCGACACCGCTGACGAACAATTCGCGCCCGCAAAGTCTCACCCCGCCCGAGAAGCACACCGAGCAGCTGCTGGGGCTGGACGCGGGCAGCATCAGCAATACGCCCCGCTCGGCCTCGACCCCGCCCAACAAGCAGTCGGGCCAGTCCGCCTCGGACAGTGCGCTGTACTCGTGCGAGTACTGCGGCAAGAAGTTCCGGTTCCAGAGCAATCTGCTGGTGCACCGGCGCACGCACACGGCCGAGCTGCCGTACAAGTGCGCCAGCTGTGAGTTCGCCTGCGGCCAGGCGGCGAAGCTGAAGCAGCACATGAAGCTGGTGCACGGCCGGCGGCGGACGTCCGTGGCGGCCATGTCGGAACCGGACTCGGGCACCAGCAACGTCGACTCGATCGAGAGCGACCCGGACGATACGGACCACGAGCTGATGGATGCGGACGAGCTGGACGCGGACGGTGAGGCCGATCGGCGTACGGCGCACGGGGACGACGAGCACGCGGACGGTGAGGACGACGAGGAGGACGAGGATGAGGACGAGGACGAGGAGGACGACGAGGCGGAAGATTTGAGCATGAGCAGCACGCAGAGCCAGTCGAAGAAGGACGGGTCGGGTGGGTCGATGTCGATGTCGACCTCGCTCGTGGGGGAGCTGATGGACAAGTTCGGCCTGTCCAACATTGCGCAGTACTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCGGGCAATGCGCTGAAGCTGCAGCTGACGAGCAAGGACCGGGACAACAACAACAGCGCGATGGCCATCCCCGGGCTGGCGGAGAAGCTGAACGGGCTGCCGGCGGCACTGCGCATCAAGGAGGAGCTGGCGAAGAACATGCTGCAGCACCATAACGCGCAGCTGCCCCAGGTCCCGCTGTTCAACCCGTTCGAGAACCCGTTCGAGGCGTCCAAGCGCATGAAGCTCGAGGGCAGCGACAGCTGGTGGGGCCTGCCCGGGATGCACCGGGGCGACGCGCTGTTCGAGAACCTGAAGCCGGGCCGGGACGGGGGCCGCGGACCGGCCGCCGGCCTGCTGCAGCCGATGATGAAGAAGGAGAGCAAGCTGCGCAACGACACGTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTGCACCGGCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCGTACGCGTGCGCCCAAAGCTCGAAGCTGACGCGCCACATGAAGACGCACGGCCGGCTCGGCAAGGACGTGTACCGGTGCCGGTTCTGCGAGATGCCGTTCAGCGAGGAAGCGGCAACGGCATGA
Protein Sequence: MLSTSEDAGFYSHNRDHSEAGESDGTTQDILTCGSCQKTFALSDIVRFIQHKVFQCNKENYGQCFTQAGGGTDRDSDDGRRLLLTGNTSSIATRRASMPNVSCRAGKQTITTASATYDDRVHTPPPTSPAELLRDGASSTPKHPGDEPENASTHCPSRGASPLGCTLDDDHRDQKPSVRAIEIKQERMDIDPASCGEEEFVSVRKQQPQTVATAHRNGSHDASESPNHTEPSNYVCSTCKTKYHSAWRLVQHVQHAHGVKIYVESLASTGSQDGDGAAPTEESDAPESAAASEAANNGPSTGEAVPAAQKRTDEQPARARTPRSRSASRSPKAVSIEREQPIRSPAPKDRSNGLEVPSKAASENGRSGESDDELEVRTKRPKLTSSSSNGSHATVNHTEEVALALTSPQPLTQTAATTTTQQRQSSTPQPLTVSSVQSPSRPQHSPPAGSGTIAAPSLAPARSESTQSLPPPSLRPHHSLLPPPELHQNPFGLLRMPPHHPHSPLFGRTHHDFRMEHLMSEQFRSHGLNLAAAAVAAANQLKSHGQQFNPATGATASERPPSAGAATSALTLTPGGGGAGVVGGLEPHMDYYSQRLRQLAGTTSPGANLTSASSNSPSPRKQPHSPSHFASPSPSHQLPPTPLTNNSRPQSLTPPEKHTEQLLGLDAGSISNTPRSASTPPNKQSGQSASDSALYSCEYCGKKFRFQSNLLVHRRTHTAELPYKCASCEFACGQAAKLKQHMKLVHGRRRTSVAAMSEPDSGTSNVDSIESDPDDTDHELMDADELDADGEADRRTAHGDDEHADGEDDEEDEDEDEDEEDDEAEDLSMSSTQSQSKKDGSGGSMSMSTSLVGELMDKFGLSNIAQYSEAYKQALQESGNALKLQLTSKDRDNNNSAMAIPGLAEKLNGLPAALRIKEELAKNMLQHHNAQLPQVPLFNPFENPFEASKRMKLEGSDSWWGLPGMHRGDALFENLKPGRDGGRGPAAGLLQPMMKKESKLRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRLGKDVYRCRFCEMPFSEEAATA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105416;
90% Identity: -
80% Identity: -