Basic Information

Insect: Anopheles coluzzii
Gene Symbol: Prdm1
Assembly: GCA_016097175.1
Location: CM027927.1:40261819-40296370[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.7e-07 8.9e-06 25.6 0.8 1 23 847 869 847 869 0.99

2 5 8.7e-06 0.00046 20.2 5.1 1 23 875 897 875 897 0.98

3 5 1.8e-06 9.5e-05 22.3 4.3 1 23 903 925 903 925 0.98

4 5 0.00061 0.032 14.4 2.4 1 23 931 953 931 953 0.97

5 5 0.0001 0.0054 16.8 0.1 1 22 959 980 959 980 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.7e-07	8.9e-06	25.6	0.8	1	23	847	869	847	869	0.99
2	5	8.7e-06	0.00046	20.2	5.1	1	23	875	897	875	897	0.98
3	5	1.8e-06	9.5e-05	22.3	4.3	1	23	903	925	903	925	0.98
4	5	0.00061	0.032	14.4	2.4	1	23	931	953	931	953	0.97
5	5	0.0001	0.0054	16.8	0.1	1	22	959	980	959	980	0.96

Sequence Information

Coding Sequence: ATGTCTGGAGCGAATCCCCCTCGAAGCGTTACGCCAAACGCGCAGCAGGACTACGATGTTACGCGTATGCGCGAGGAAGACTTCGAGCGGCTGGCGGTGTACATCGTGCCGGACATGCCCTGCGAGAAGGGTGTGCCCGGCCGGGCGGAGAAAACGCTCCCCCGCAGCCTGACGCTCAAGCCCTCCCTCGTCCTGTCGACGCCCACCTCCACGACTGAGGGCGTATGGAGTACGGGTGTCATCCCGCGCGGCACCCGGTTCGGCCCGTTCGAGGGCGTCCGCACACCGAGCCACCCGAGCGATAAGCAGCTGTGGCGGTACTTCTGGAGGGTGCAGGAACTGCGACACGTTTCCTATGGGAATATCAAGATATTCAAAGACAGTGATTTCTACTATCTCGACGGGTCGGATACGGCCCAATCGAACTGGATGCGGTACGTCGCGTCCGCGTACAGCTTCTCCGTGATGAATCTGGTCGCCTGCCAGCACCAGGAGCACATCTACTTCTACACGATACGCGACATCATGCCGAACGAGGAGCTGATGGTGTGGTACTGTCGCGACTTTGCCAAGCGGCTCGGCTACGACATCGATCCCGAGCGGGCGACCTACTCGATCTGCCGCGAGGAGGTCGTGAAGAAGACGTACAAGCAGCCCGTCCCGCCGGAGATCGCCTACAACCACGTGAAGCACGTGATGGGCCTCTACCTGCCGGCGATGGTGCGCAGTACGCCAACGCCCAGTCCCTCACCACCGGCGCCCGCAACCGTCGGTGGTCATGTTCCTTCCGCGAAGCATCACGCCCTGCACCAGACGGTACTGCGCGAGCCTCGCAATAGCAGCTCGGCGGCGGCCGTCACCGGCGATGAGTCCCTGCGGGACCGATCGCCCATCAGGATAGTGATCCGCGAGCAGAGCCCACTGTTGCGCGAAAGCGTCAAGGAGGTCGATGCCGACTCTCCGATCTCACAGACGAAAGAGACGGCGTACGAGCATCAGCTGACGCCGAACGATGGGTCGGTACGGTCGGACGAGGGCTACCACAGCCACGGGTACCACGAGGATGGCTTCACGCCCCCGGAGGACTCGAGCGACAGCGAGAGCGAGCACAACTACGTGCTCGACTGCTCGAAGAAGGCGATCGAGCCGAAGGAGACGAGCGTCGGCCAGCACAAGGTGAGCACGAGCGAGCCGTGCGACAAGAACGAGTACCGCAAGGTGAAGATGAAGATGCCGCTCAAGTACGAGTTTAAGAACAACAGCAAAAACTTCAAGGTAGAGCCGGAGCTGGAGCCAACCGAGCGCGAGGTGGAGCCGGCGGTGCCCGCGAGCAGCGAACCGGTGGTGGTGGGGGCGAGCATGCGGGAAGTAACGCCCGCCACCAGCACCGTGATCGTGCTCGACACGACACCGGAGTCGTCGGTGGTAGTGCCGCTCACCAAGAGCTACTACGAAGCCGAACCGACCTCGACCTCGCCCGCGACCTTCATCCGCTACACGCCGCCCAGCTCGAGCTCGATCCTGGAAACCATCCTGACCGGCAGCCAGCGCGCGTCCCCGTCGGCGGACGATCCGCACCGGCGGCAGCCGAACGCGACCCCGCCCCCGACCTCCCCGACCGAGATGGCCTACTCGTACAAGAAGTCGCAGCGGTACGGGACGGCCTGCAGCCCCGACTCGAGCTCGCAGAACCCGCAGGCCCCCGAACCGGCCGAACCGGGCCACGGGCCGAACCGATCTCAGCCGCACCATCACGGCGCCGCCGGTCCCGAGCCGAAGGAGGCGGACCACGCGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGACGGCCGCCACCTCTCCCTCGCCCTCGCCCATCGTGTACCCGGGCGAGCACCATCCGCACCTGCACCATCCCCATCACCATCTGCCGCCGCACCATCACCACCGAACGCACTCGCCGGTGGCGTACGAGTCCCCGGTACCGAGCTACACCGCCACCAGCAGCAGCGGCAGCCTCTACTCCACCTCGAACGGGTCGGCCAGTGTGATCAACAGCGCTTCCAGCTCCACCTACAGCCCGCCGCTGAACGGTGGCCACTACGAGAGACTGACGACCTCGTCGACCACGCCAACCATCCGCTCGGTGTCGCCGCCGCCGCCACCACCAACGCAACCAGCGCCGGCCCCAGGCTACGTGCAGCTCCAGTCGAAGGGGCAGCTACCGCTGGGCCACCCGCTAATGCAGCCCCTAACGCCCCTCACGCACATGTCCCCGGGGCGTATCTCGCCCCCGAGCAGCCTCAGCCCGGACGGTGGTTCGTACTCGCGCAGCGGCAGTCCCATGTCCCCGGGCAGCCCGAACTCGCGCGGCTACCGCAGCCTGCCGTACCCGCTGCGCAAGCGCGACGGCAAGATGCACTACGAGTGTAACGTGTGCAGCAAAACGTTCGGCCAGCTGTCCAACCTGAAGGTGCACCTGCGGACGCACTCGGGCGAGCGGCCGTTCAAGTGCAACGTCTGCACGAAATCCTTCACCCAGCTCGCCCATCTGCAGAAGCACCATCTGGTGCATACGGGCGAAAAGCCGCACCAGTGCGACATCTGCAAGAAGCGGTTCAGCTCGACCTCGAACCTGAAGACGCACCTGCGGCTGCACAGCGGCCAGAAGCCGTACGCGTGCGACCTGTGCCCGCAGAAGTTCACCCAGTTCGTGCACCTGAAGCTGCACAAGCGGCTGCACACGAACGACCGGCCGTACGTGTGCCAGGGCTGTGATAAGAAGTACATCAGTGCGTCCGGGCTGCGCACGCACTGGAAGACGACCAGCTGCAAGCCGAACAATCTCGAGGAGGAGCTAGCGATGGCGGCGGCCGCCACCTCGGAGTGTTTGGATAAGGACGGCCAGCCCGACGGGGAAGGTGGCCGCGAGTTCTACGAAATGTCTCACCACGGTTCGCCGGGCGGCGTTGTCGTACAGCAGACGGCGGCCGCACTGTCACCAGCGTCGCACCACCAGCATCACCAGCACGCCGGCCATCACCATGGCACCGAGCAGGTCATACACAAGGTGTCGGCCGGGAAGATCCAGCAGCAGCAGCACCAGGGACCGTCCCCGTCGAACAGCAGCAACAACAACAGCCCCAACAGTACCAACCACAATCTATCGTCCTCGCCGCACCTACACTACGGTGGCCATTTGGTGCAGTCGGGTGGCGGTGGCAATGGTACGGCGAGCGGTGGGCCCGGTCCGGCCCAAAGCCAGCACGAACCGGCCAACCGGCCTAGCGTGATCGAGTCAAGCCAGCCGATGGTGATCGAGTGCACGTAG
Protein Sequence: MSGANPPRSVTPNAQQDYDVTRMREEDFERLAVYIVPDMPCEKGVPGRAEKTLPRSLTLKPSLVLSTPTSTTEGVWSTGVIPRGTRFGPFEGVRTPSHPSDKQLWRYFWRVQELRHVSYGNIKIFKDSDFYYLDGSDTAQSNWMRYVASAYSFSVMNLVACQHQEHIYFYTIRDIMPNEELMVWYCRDFAKRLGYDIDPERATYSICREEVVKKTYKQPVPPEIAYNHVKHVMGLYLPAMVRSTPTPSPSPPAPATVGGHVPSAKHHALHQTVLREPRNSSSAAAVTGDESLRDRSPIRIVIREQSPLLRESVKEVDADSPISQTKETAYEHQLTPNDGSVRSDEGYHSHGYHEDGFTPPEDSSDSESEHNYVLDCSKKAIEPKETSVGQHKVSTSEPCDKNEYRKVKMKMPLKYEFKNNSKNFKVEPELEPTEREVEPAVPASSEPVVVGASMREVTPATSTVIVLDTTPESSVVVPLTKSYYEAEPTSTSPATFIRYTPPSSSSILETILTGSQRASPSADDPHRRQPNATPPPTSPTEMAYSYKKSQRYGTACSPDSSSQNPQAPEPAEPGHGPNRSQPHHHGAAGPEPKEADHAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTAATSPSPSPIVYPGEHHPHLHHPHHHLPPHHHHRTHSPVAYESPVPSYTATSSSGSLYSTSNGSASVINSASSSTYSPPLNGGHYERLTTSSTTPTIRSVSPPPPPPTQPAPAPGYVQLQSKGQLPLGHPLMQPLTPLTHMSPGRISPPSSLSPDGGSYSRSGSPMSPGSPNSRGYRSLPYPLRKRDGKMHYECNVCSKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDGQPDGEGGREFYEMSHHGSPGGVVVQQTAAALSPASHHQHHQHAGHHHGTEQVIHKVSAGKIQQQQHQGPSPSNSSNNNSPNSTNHNLSSSPHLHYGGHLVQSGGGGNGTASGGPGPAQSQHEPANRPSVIESSQPMVIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103955;
90% Identity: iTF_00104688;
80% Identity: -