Basic Information

Insect: Anopheles coluzzii
Gene Symbol: ZNF473
Assembly: GCA_016097175.1
Location: CM027927.1:49361368-49362327[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0026 0.14 12.4 1.9 1 23 88 110 88 110 0.98

2 8 0.099 5.2 7.4 0.2 2 23 114 135 113 135 0.84

3 8 2.5e-05 0.0013 18.8 1.6 1 23 147 169 147 169 0.98

4 8 1e-05 0.00052 20.0 0.2 2 23 173 194 173 194 0.95

5 8 8e-06 0.00042 20.3 1.2 1 23 208 230 208 230 0.99

6 8 6.4e-05 0.0033 17.5 0.5 2 23 234 255 233 255 0.96

7 8 0.00051 0.027 14.6 5.3 1 23 267 289 267 289 0.98

8 8 0.041 2.2 8.6 1.0 2 20 294 311 293 315 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0026	0.14	12.4	1.9	1	23	88	110	88	110	0.98
2	8	0.099	5.2	7.4	0.2	2	23	114	135	113	135	0.84
3	8	2.5e-05	0.0013	18.8	1.6	1	23	147	169	147	169	0.98
4	8	1e-05	0.00052	20.0	0.2	2	23	173	194	173	194	0.95
5	8	8e-06	0.00042	20.3	1.2	1	23	208	230	208	230	0.99
6	8	6.4e-05	0.0033	17.5	0.5	2	23	234	255	233	255	0.96
7	8	0.00051	0.027	14.6	5.3	1	23	267	289	267	289	0.98
8	8	0.041	2.2	8.6	1.0	2	20	294	311	293	315	0.75

Sequence Information

Coding Sequence: ATGGAGTTCCACGACGAGATCGTTATAGAACGCACCAAAATAATGGCCGTCAAGGCGGACAATTCGTTCCAGTATGAGGAGGTACAAATCAAAGAAGAAATTGCATCTGATTCAGAGGTAATAGTACCGGTAATAAGCAACGGAAAGAAAGCAGGGGCACAACAACAAAGCAACAGCAAACATCACGTGCACGAAGAAGATATTCCGTGTGGCCTTTACCCATTGGAAGATAACAACAATAATGCAAAAGGCAGGGCTAAGCATCAATGCGAGAATTGCCTCGAATCGTTCGACAGTATCGTACGCCTGCGTCGGCACGAGCGAAAGCATTGGATGAAAAGCTGCCCAATATGCGACAAGACGGTGCAGGTGGATAATTTAAAGTTTCACATCGGTCGTATGCACGGTAGCGATGAGCGGTGTGCTGAAAAACGGCCCTTCCAGTGCACGGAATGCGATAAATCGTTCTTCCTCCCGAACCACCTGTTAGAGCATGGGCAGACGCACCAGAAGGCAAGCTGCCCGGTGTGTGGGGAATCGTTCAGACCGTCCTACCTCAAGAACCACATAGCTAGAAAGCATCCGGACGGTGACGCGGGACTTTCGAAAACCCCCACCGTGTACCGTTGCAGTGCATGCAAGCAAACGTTTGTCAGTAAATCCTTGCTCTGGACTCACCAGCAGATGCATAAGAAGGTGGAGTGTACTATATGCAACAAAACGTTCCGGCAGGATGGTATGAAAATGCACATGGCCACCACCCATCGGGAGTATCTGTCGCCTTCGGAGACTCCATCGTACAAGTGTGATAAATGCGAACGGACATTCCTGTACAAAAAGCAGCTGACGAAGCACAAACGCTACCACCCCCGGATGGTAAAGTGTGCGATTTGTGAACGGTCGTTTAAAACGAACCACTTCAAAATCCACACAGCAGAGGAACATGGTGCACCGGAGTAA
Protein Sequence: MEFHDEIVIERTKIMAVKADNSFQYEEVQIKEEIASDSEVIVPVISNGKKAGAQQQSNSKHHVHEEDIPCGLYPLEDNNNNAKGRAKHQCENCLESFDSIVRLRRHERKHWMKSCPICDKTVQVDNLKFHIGRMHGSDERCAEKRPFQCTECDKSFFLPNHLLEHGQTHQKASCPVCGESFRPSYLKNHIARKHPDGDAGLSKTPTVYRCSACKQTFVSKSLLWTHQQMHKKVECTICNKTFRQDGMKMHMATTHREYLSPSETPSYKCDKCERTFLYKKQLTKHKRYHPRMVKCAICERSFKTNHFKIHTAEEHGAPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104604;
90% Identity: iTF_00107211; iTF_00104604;
80% Identity: -