Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027928.1:52241006-52242887[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0023 0.12 12.6 0.7 2 21 93 112 92 113 0.94

2 7 0.00065 0.034 14.3 0.4 3 23 130 150 130 150 0.99

3 7 0.0011 0.059 13.5 1.0 3 23 173 193 171 193 0.97

4 7 2.5e-06 0.00013 21.9 1.6 2 23 200 221 199 221 0.95

5 7 0.00016 0.0084 16.2 0.5 1 23 226 248 226 248 0.99

6 7 8.2e-07 4.3e-05 23.4 2.6 1 23 255 277 255 277 0.98

7 7 1.8e-05 0.00096 19.2 0.4 1 23 283 306 283 306 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0023	0.12	12.6	0.7	2	21	93	112	92	113	0.94
2	7	0.00065	0.034	14.3	0.4	3	23	130	150	130	150	0.99
3	7	0.0011	0.059	13.5	1.0	3	23	173	193	171	193	0.97
4	7	2.5e-06	0.00013	21.9	1.6	2	23	200	221	199	221	0.95
5	7	0.00016	0.0084	16.2	0.5	1	23	226	248	226	248	0.99
6	7	8.2e-07	4.3e-05	23.4	2.6	1	23	255	277	255	277	0.98
7	7	1.8e-05	0.00096	19.2	0.4	1	23	283	306	283	306	0.98

Sequence Information

Coding Sequence: ATGGATGGCTCCCAAGAGGAACTCAATTTAGAGTTTAATATCATCGATAACATCATTGAATCAGCTGTGGGCGATCTGCTGCTGAAGGACAATAATAGCGTCCACTATGAGTACAAAACCAACTTGAGCGAGTATTTTGAAAACGTGGAAAACATCAACAATGCCCAACGGTTCGATGCTGTGATAGAGGAAAAGTCGAACGACACGATCGTGAATCGAAAAAGATCACAAAAAACCGAAGCTCGCCGCCGCGTTGTGGACGGGCGGCTGGAATGGGTCTGCCTAGACTGCGAGCAGGTGTTTCCCAGCTGCCTTCAGCTAAAGAAGCATCGACGAAACTGTGAACTGGTGGGTAGCAAAACGTCCAAACGCTTCGCAACACTTGGCTGTGATATTTGTGGCGAAACCATGTCCACGGAATCGGCGCTGACTATGCACAAGCGCAAGCATGAAACGAAGGTAAAACGTCCGCCCGCATTAAAACCCCTTCCCTCTCCCAATTTGGAACCCATCTTTTGCGATGTGTGTGGTCACGCGAGCAAATCGAAACGCGCGCTTCGGCTGCATCGAATTACCCACAGCAACGACAAGCAGGTGGAGTGTCATGTTTGCGGCAAACGGTTCAAGCGCCGCCGCACACTCCGCATCCATCTGGAAGGCCACTCGGGACAAAAGTACGAATGTGAAGTGTGTGGCAAACAATTCCTAACCACCGTCACCCTACGGAACCACGCAAAAACGCACAGGAACAGTGATGTAATGCACGAGTGCACCGTGTGCCAGCGACCGTTTGCGCATCCGAATCAGCTACAGAAACACATGATGACGCATACGGGCGAGTATCCTTACGTGTGCGAAATTTGCAATGCAATGTTTCGCACACTCGGGCGGTACAATCGGCATATGCAGAGGGGACACGTGCTGCCAGAGAGCTTGAATGTAATCGAGCAGACAGAGACGAACAGTTGGGACGATTTGATCGAGTACCAGCCGGAGTCAATGCTGAGTGACACGTTGGACGAGACACGGTCGGATGTGATGCTGGGGATGGGCGAGTCATCGAGCGACACGTCCTTGCCGGATGTGCTAAGCAACTATGCATCGGATCATCAGCCGTTCGATCAAGCTCCGGGAGAGTTTGCAGTGCAACGCGTTGAGCCGATTTATGCCTTCATCGATTGCAACTAA
Protein Sequence: MDGSQEELNLEFNIIDNIIESAVGDLLLKDNNSVHYEYKTNLSEYFENVENINNAQRFDAVIEEKSNDTIVNRKRSQKTEARRRVVDGRLEWVCLDCEQVFPSCLQLKKHRRNCELVGSKTSKRFATLGCDICGETMSTESALTMHKRKHETKVKRPPALKPLPSPNLEPIFCDVCGHASKSKRALRLHRITHSNDKQVECHVCGKRFKRRRTLRIHLEGHSGQKYECEVCGKQFLTTVTLRNHAKTHRNSDVMHECTVCQRPFAHPNQLQKHMMTHTGEYPYVCEICNAMFRTLGRYNRHMQRGHVLPESLNVIEQTETNSWDDLIEYQPESMLSDTLDETRSDVMLGMGESSSDTSLPDVLSNYASDHQPFDQAPGEFAVQRVEPIYAFIDCN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101163;
90% Identity: iTF_00101163;
80% Identity: -