Basic Information

Insect: Anopheles coluzzii
Gene Symbol: prg
Assembly: GCA_016097175.1
Location: CM027930.1:33403306-33405366[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.14 7.6 6.9 0.5 1 23 240 263 240 263 0.80

2 9 0.017 0.89 9.8 1.2 1 23 298 320 298 320 0.92

3 9 1e-09 5.4e-08 32.5 2.1 1 23 326 348 326 348 0.98

4 9 0.0001 0.0052 16.8 1.0 3 23 356 376 355 377 0.95

5 9 0.28 15 6.0 0.2 5 21 387 403 383 404 0.87

6 9 6.6e-05 0.0035 17.4 0.5 1 23 480 502 480 502 0.98

7 9 0.0045 0.23 11.7 0.4 1 23 511 533 511 533 0.99

8 9 1.7e-05 0.00088 19.3 2.9 3 23 541 561 539 561 0.97

9 9 0.00026 0.013 15.6 1.3 1 23 568 590 568 590 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.14	7.6	6.9	0.5	1	23	240	263	240	263	0.80
2	9	0.017	0.89	9.8	1.2	1	23	298	320	298	320	0.92
3	9	1e-09	5.4e-08	32.5	2.1	1	23	326	348	326	348	0.98
4	9	0.0001	0.0052	16.8	1.0	3	23	356	376	355	377	0.95
5	9	0.28	15	6.0	0.2	5	21	387	403	383	404	0.87
6	9	6.6e-05	0.0035	17.4	0.5	1	23	480	502	480	502	0.98
7	9	0.0045	0.23	11.7	0.4	1	23	511	533	511	533	0.99
8	9	1.7e-05	0.00088	19.3	2.9	3	23	541	561	539	561	0.97
9	9	0.00026	0.013	15.6	1.3	1	23	568	590	568	590	0.98

Sequence Information

Coding Sequence: ATGGGAACGACGCCACCGCCAGCACCACCGCTGCAACTGGGGATGAACATCGCTAATGGGCCGACTGCAACGGCGGAGCGGCAACTTTGCCGGCTGTGCTTGGGACGGGACGGGGAGCTGGTGGATATTTTCGCGGCCCAGCAGCAGACGCCACACAGCGGAGAGTCACTGGCCGGGCGGATACAGGGCTGTCTGCAGCTGGATGTCACACAGCACGATACGCTGCCGAGATGGATCTGCAAGCCGTGTCTGGAGAAGGTGGACGACTTTGCCGCCTTCCGGGAGCGCTGCAAGCAAAACGAACGGAAGCTACTGCTCGGGGAGGAAGACATACTGCACACGAAAGATGGTCCGGCAGTGGGACCGACTGGCGAGCAAACGGAGGAGGAGGAGGAGGATGACGATGAGGAGATGGAAATGATTGTAATTGATCCATCGCGGGACTACGAAAGCTCGAACGATAGCCTGCCGCATCGTTCCGAGCCGAGTGGTGTGGTGAATGGTGGCGATCCGGCAGCAGCACTACAACCCGAACCACACGCCGAAGAGGAAGAGCCCGAAGGCTCCGACGCAGACGAAGGCGATGAGGAGGAAGAAGAGGAGGAGGAAGATGAACTGAAATGTGATACAGCGCCGGGTGGGACAGCGCCGAACGGGCTGCCGGACACCAGCTTCCACACGGCAGCGTCGAACACGGCGCCCCAAAAAACGGTCGTCTTCACCTGCAAGTACTGTGACGTGGCGTTCGCAGCCGCATCCGCCTGCCAGCTGCACGAGATGCAGGATCACGATCTGCTCGCACCGTACGCGTGCATCTTCTGCCAGTACAAAACCTCCATCCGGATGTTTCTCATTACGCACATACGGGATTCGCATGCGGTCACCCGCCCGTATATTTGTATCCAGTGCAATAAGGGCTTTTTGCGGCGGTCCGACCTGAAGAAGCACACGTTCGTGCATACGGGCGTGCGGCCGTACGCGTGCGACCAGTGCGGTAAGAGCTTTTCGCGCAACACGAATCTCAAGAAGCACATGCGCACCCATCTGGGGGTGAAGCCGCACGGGTGCGATCTGTGCCCGCGATCGTTCGCGAACAAGGCGGATCTGATACGTCACCGCAGCTTTCATCATGCGCAGGAAACGCAGCATGCGTGCATACGGTGCGGTGCGGTGTATACGCAGAAGGACAAGCTGTACGATCACGAGCGGTACTGTATGGGGAAACCGTTGCCGTTCGGGATGGGTGAGATGGTGAAGCAGGAACCAGCACCATTTGGGTTGAGTGTAACTGCTCCCATTCCACCACCACAACCAGCGCAACTGCTGCAAGCCTCCGAACCGATTGTACACAGCGAACAGCCACCGAGTTACGTTCCCGTGCAGCCTGTAGCTGCACCACCACCACCTGTAGCAGTGACACCACCGTCGAGCAAAATCTACAGCTGCACCAAGTGCCCGAAACGGTTCCTCAGCAAAGCGAGCCTGCGCGCACATCAGGCCATCCACCCGGCCGAGGTAGACGCGCGCCCGTACGAGTGTCCCGTGTGCCGGAAGCAAATCGTCGGCAAGCGCGAGTACGATCGGCACCAGCAAACGCACAGCGAGCTGAAACCGTTCGGCTGCGGTACGTGCGGGAAGCGGTTTTCGCGGCGGGACAAGCTGCACCGGCACGAGCGCATCCATCAGCAGGCGGAGCGACACTTCACCTGTTCCCACTGTGCGGCACGGTTCGTGCGGAAGGATGCTTACGAGTCGCATCTTAAGGTGCACTGCGCACCGCTGTACGGTGCGGTGCAGGAGATGGCGATGCCAACGATGCAACAACAGCCACAGCAACAGCCACCATCACAACAACATTCCCTGCTGTACGCGATGATGGGTGGCGATGATGGGGCGCTGCTCGGGGTCGACCCTTCGCTGCGGATGTGA
Protein Sequence: MGTTPPPAPPLQLGMNIANGPTATAERQLCRLCLGRDGELVDIFAAQQQTPHSGESLAGRIQGCLQLDVTQHDTLPRWICKPCLEKVDDFAAFRERCKQNERKLLLGEEDILHTKDGPAVGPTGEQTEEEEEDDDEEMEMIVIDPSRDYESSNDSLPHRSEPSGVVNGGDPAAALQPEPHAEEEEPEGSDADEGDEEEEEEEEDELKCDTAPGGTAPNGLPDTSFHTAASNTAPQKTVVFTCKYCDVAFAAASACQLHEMQDHDLLAPYACIFCQYKTSIRMFLITHIRDSHAVTRPYICIQCNKGFLRRSDLKKHTFVHTGVRPYACDQCGKSFSRNTNLKKHMRTHLGVKPHGCDLCPRSFANKADLIRHRSFHHAQETQHACIRCGAVYTQKDKLYDHERYCMGKPLPFGMGEMVKQEPAPFGLSVTAPIPPPQPAQLLQASEPIVHSEQPPSYVPVQPVAAPPPPVAVTPPSSKIYSCTKCPKRFLSKASLRAHQAIHPAEVDARPYECPVCRKQIVGKREYDRHQQTHSELKPFGCGTCGKRFSRRDKLHRHERIHQQAERHFTCSHCAARFVRKDAYESHLKVHCAPLYGAVQEMAMPTMQQQPQQQPPSQQHSLLYAMMGGDDGALLGVDPSLRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107179;
90% Identity: iTF_00101162;
80% Identity: -