Acol012823.1
Basic Information
- Insect
- Anopheles coluzzii
- Gene Symbol
- -
- Assembly
- GCA_016097175.1
- Location
- CM027930.1:25462230-25464203[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0013 0.066 13.4 0.0 2 23 232 253 231 253 0.96 2 12 7.7 4e+02 1.5 1.8 1 23 259 286 259 286 0.78 3 12 1.7 91 3.5 0.9 1 23 290 313 290 313 0.87 4 12 0.0017 0.088 13.0 0.2 1 23 319 341 319 341 0.97 5 12 4.4e-06 0.00023 21.1 0.6 1 23 349 371 349 371 0.98 6 12 0.0039 0.2 11.9 4.6 1 23 377 399 377 399 0.97 7 12 0.0089 0.47 10.7 1.5 3 23 408 430 406 430 0.90 8 12 1.9 99 3.4 0.0 3 23 458 480 456 480 0.94 9 12 0.00085 0.045 13.9 0.2 1 23 484 507 484 507 0.95 10 12 4e-05 0.0021 18.1 1.4 1 23 513 535 513 535 0.97 11 12 8.3e-07 4.3e-05 23.4 1.0 1 23 541 563 541 563 0.98 12 12 0.11 5.8 7.3 0.1 2 21 574 593 574 594 0.93
Sequence Information
- Coding Sequence
- ATGCTCTCCGTGTGTCGTTTGTGTGCCCGGTGGGGTGAACCGTTTGCAGAAATGGACACCATACTGGTAGAGAATCTGCAGCCAAACAAGGCGATCATGCGAATGTTTGGCTTCGATCTTTCTTGTTCACCATCGTACCCGAACCAAGTGTGCCACGAATGTGTTCAAAGCCTAGAGTACAGCTTCGTCTTCCACCAGCAGCTGGTGAATGCGGAAACGCTGCTCCGTACGCTGCTTGAAAAGGGTCAGCTTGAGCAGCGTTTGCTGGAGAAGAAAGAGGCAGGAGAATCACTGCAGCCAGCGGTGGAGCTGTTGGAAGTGATTCCACTTTCCGATATGCCACATCACAGCGAGGCTGGCTATGCTGACCCACACGAACCAAAGAAGACCGTCGAGAGTTTAAGCGATGGGGGAGAATCACTGCCGGAAGAGAATGGCTGGCCCGATAAGTCGGCGGAAAAAGTGATCGAAATTAAGATCGAAGCCATCGAGGAGTTGGAAATTATAAGCAGCCCACTAGAGGGCGGTGAAACAAGCGGTGTGCCATCTCAGGGAGCAACACATACGTGCGATGATGAAGAATCGCTTTTCCTGCATCGAAAAAACAGCGGCGAAGCAGCGTTGGAGCTAACGAACGAATCGAACCGCATTTCCAATGCCGAACAGAAAGCGATCCGTGCAATCGTGCCCAACAAATGTTACGTGTGCTACAAAGTGTACGCCAACGAGGCCGAACTGACGGCGCATCTGATCGAGCACAACGAGCTGCTTCCCTTCCGCTGCCGGCAGTGTAGTACAACCGACCGGGTGTTTGAGTATCGTACCATACGCGCCCTGAACAAGCATCTCGAATCGCACCGCTACCCGTTCGATTGTGGCGAGTGTCGGTTGCGCTTCCGCAAGATAACTGCCCGCAACGATCACTTTCTGCGCATGCACATGTCCGAGGGCGTGTACACGTGCGAACGGTGCGGTGTGGAGTTTCAAGATGCGCGCAAATTTCGCCTCCACATGGCCGCCCACCGGAACATGGAGCTGCAGCGGTACAAGTGCCCCGTCTGCTCGAAAGCCTTCCAAAGCAGCACACTGCTCGAGCGGCACAAACAGATACACGCTGCGAAACCACTGTTCCAGTGTCAGCACTGTATGCGTGGGTTTAACTCGAAAAGCAACTACATGCAGCACAAGATGCTGCACCTGCAGCAGAACGCGTTGATACACTGTGGGGAAACGGGCTGCCGGCAGAACTTTACCAACTACCGCGACTGGCGCCGGCACATGAAGGCACACTACCCGCAGGAGGCGGTGTACTGGGAGTGCAGGGACATGCTGCCGGTTACGCTGCACGATACGACCGGCTACCCGCAACCCTGCCCGGAAGCGGGCTGTACGTACGTTGCCGCATCGCTGCCACTCATGTTTGCCCACTACCGCGTGCACTACAAGGCGTTCCGGTGCGTGCAGTGCGATGGTAGGTACTCGAACGCATCGGCCCTGCGGCAGCACGTGGAAATACGCCACGAAGGTGTGCGCCGGTTTGAGTGCGATCGGTGCGGCAAACGGTTCGCGTACCGGCATAAGTTGCGTGAACACGTTGCTGTCCATCTGGGGGTGCGTAGCTTCAAGTGTAAGCAGTGTCCGCGTAAGTTTACCAGCTCATCGAATCTGGCCGCGCACGGGAGTACGCATGCGAGCGAACAGGCTGCCAACAGCAGCCGGCGTTGTGCGCTGTGCGCAACGACGTTCGTATCTGCGGCGGCACTTGCGCATCATCATCAGGAGTACCTGCGATTGGGCCAATCGGGCGCGAGTGCGTGCGAAAGGATCCAGGCAAGGAGGCAGGAGGAGGAGGGTTTGCTGCGGCAACGTGAGATGGAGTCGTCCAGCGATTAG
- Protein Sequence
- MLSVCRLCARWGEPFAEMDTILVENLQPNKAIMRMFGFDLSCSPSYPNQVCHECVQSLEYSFVFHQQLVNAETLLRTLLEKGQLEQRLLEKKEAGESLQPAVELLEVIPLSDMPHHSEAGYADPHEPKKTVESLSDGGESLPEENGWPDKSAEKVIEIKIEAIEELEIISSPLEGGETSGVPSQGATHTCDDEESLFLHRKNSGEAALELTNESNRISNAEQKAIRAIVPNKCYVCYKVYANEAELTAHLIEHNELLPFRCRQCSTTDRVFEYRTIRALNKHLESHRYPFDCGECRLRFRKITARNDHFLRMHMSEGVYTCERCGVEFQDARKFRLHMAAHRNMELQRYKCPVCSKAFQSSTLLERHKQIHAAKPLFQCQHCMRGFNSKSNYMQHKMLHLQQNALIHCGETGCRQNFTNYRDWRRHMKAHYPQEAVYWECRDMLPVTLHDTTGYPQPCPEAGCTYVAASLPLMFAHYRVHYKAFRCVQCDGRYSNASALRQHVEIRHEGVRRFECDRCGKRFAYRHKLREHVAVHLGVRSFKCKQCPRKFTSSSNLAAHGSTHASEQAANSSRRCALCATTFVSAAALAHHHQEYLRLGQSGASACERIQARRQEEEGLLRQREMESSSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00107169; iTF_00104581; iTF_00093653; iTF_00101147;
- 90% Identity
- iTF_00107169; iTF_00104581; iTF_00093653; iTF_00101147;
- 80% Identity
- -