Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027927.1:39936658-39941767[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0014 0.076 13.2 1.8 1 23 376 398 376 398 0.96

2 9 5e-07 2.6e-05 24.1 1.7 1 23 404 426 404 426 0.98

3 9 9.4e-06 0.00049 20.1 0.8 1 23 435 457 435 457 0.97

4 9 0.0053 0.28 11.4 0.3 1 23 463 486 463 486 0.95

5 9 4.4e-06 0.00023 21.1 0.6 1 23 524 547 524 547 0.98

6 9 0.016 0.81 10.0 3.7 1 20 551 570 551 573 0.93

7 9 8.8e-06 0.00046 20.2 1.4 1 23 579 602 579 602 0.97

8 9 5.8e-05 0.0031 17.6 0.2 1 23 657 679 657 679 0.91

9 9 0.23 12 6.3 0.0 1 20 688 707 688 711 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0014	0.076	13.2	1.8	1	23	376	398	376	398	0.96
2	9	5e-07	2.6e-05	24.1	1.7	1	23	404	426	404	426	0.98
3	9	9.4e-06	0.00049	20.1	0.8	1	23	435	457	435	457	0.97
4	9	0.0053	0.28	11.4	0.3	1	23	463	486	463	486	0.95
5	9	4.4e-06	0.00023	21.1	0.6	1	23	524	547	524	547	0.98
6	9	0.016	0.81	10.0	3.7	1	20	551	570	551	573	0.93
7	9	8.8e-06	0.00046	20.2	1.4	1	23	579	602	579	602	0.97
8	9	5.8e-05	0.0031	17.6	0.2	1	23	657	679	657	679	0.91
9	9	0.23	12	6.3	0.0	1	20	688	707	688	711	0.92

Sequence Information

Coding Sequence: ATGAAGTGTTTCGTGTCTGGGTGTGACACAGACGATAACGTCGTCAGTTATACATCTGTGTTTTACGTAAACTGCCCTACCGATCCGACCATCCAGCAGCAATGGTTCACCCTGCTGGAGGTGACCGATCCCGATGCCATGCGTGCGCTGGTAGACGGACGATCGAAAGTGTGCAGCTGCCACTTTACGGAGGACTGCTTCGGGCATCATCCGGTGTACGGGTATCGCTATTTACTCGCCACGGCCTTACCCACCGTTTTCCCCCCGCGGAAGGAGATTGAACAGCCGAAGCCCGACAGCGCGGAGCTGGAGAAAGATCCGGCGCTTGATTATTTTCTAGTCTATCTAGACGATCCTCCCGGGCCGGCCTTCATCGACCAGGTGGCATTGGCGGGCGTGACCAGTGGGCTTGATGTGATTGGAAATAACACTCCCTTGGAAGTGAAGCCGGAACAAGAACAAGCGACCATCCAAGAGGATGACGCGGAGCTACAAGAGGAATCCAACGATGTGGTGACGATTGAAGATGAAGATGGCGAAGACGACGATGCCATTGAACAAATCGGTATAGAGTACGCCAATGGCAAGTACTACTTTCTTAAGCTGGATGATGAACCCGCCCCCGTCGGTGATGTGCTTGTTTCGGCAGAGGAACCGAATGGAAACGAACTGGAATTCAGGAACAGCGAAAACGCCACATCAACTGATGCAGATCAGGAAAAGAGTTTACATGATCTGAACGAGAATTTACAGCAGCTGGACAAATTCGTTAGCCAGCAAGATGTAGGAGAGGCGGACGAGTATGACGAGTACGAGATGGATGTAAGCGACCAAGAAACAGAACAGTTTGCCGGCAAGCAAGTGCACTTAGAGACGGTGGAAGAGAGATCGGATACAGATGTGATCGAGGTAAAGGACGATACGGAAGTTGATGTTGTGAAGGAAGAGTATGAAGTTACATCGTCCAAGGATACGGACAGCGACTCGGAAACGGGTGGCGACGACAACGACTACGACTGCGACGCATTGAGCGAGGCAGATTATGGACCGATCGAGGCACTGGAGGAGGTGTCGGTGTGTGGTGATAAAGTTCGGATTCGCGATGAGAACGAAGGCCTAAACCGATTCTTTTGCGAATATTGTGGGCGAGGATTCCGGTTTAAAAGCTTGAAGGATCGCCACACCCTGGTACACACGAAGATGAAAAAGTTTTGCTGCGAAGTGTGCGGAAGAGGCTTTACGCAAAAGATCAACCTAACCATCCACCTGCGCACGCACACGGGCGAAAGTGGGAACAAAAAGTTCACCTGTCAGATCTGCGGGAAGAAGTGCATCCGGATGAGCGAGCTCGAGGCGCACATGACCGCCCATCTGCGCAAGTTCCCGCACGTGTGTCCGCTCTGCCAGGAGCGCTATTCGGACGCGACCGGGCTGTACGACCACTTCCAGGTGGAGCACCGGAGCGAGATGACGCTGCGCGAGCTGATCGATCTGCTGTCCGAGAACGAAAACGCAATCGTCATCTCGGACAAGGAGGCACCGTCCAACATTAGGCGGGACGATGGTTCGTACGAGTGTCCCGTGTGCAGCAAGACGTACCGCATGGAGGCCAACCTCGAGCGGCACAAGCGCAAGATGCATGTGAAAATTTACAACTGCCCACACTGTCCGCGCAAATTTCTGTACAAAAGCCTGCTGCACAAGCATCTGCCATCGCACACGCTCGAGAAGCCGTACCAGTGTCCGCACTGTGCGCTTTCCTACACGCAGCGCGTCAACCTGCGGGTGCACATGGAGCGCAAGCACGCGCAGCAGCTGAAGCAGCCGAAGAAGGAACCGAAGGCCGCCAGCGAGCCGTCCTTTGTGGTCGCGACGCTCAACGCTGACGGTGACGTTGTGGAGAGCATTGAGACTGCCCAGTCGCCGGCGCCGCCGCCTCCGCCGCCACGGATCACCGGGCCGCGAACACACGACTGTGAGGAGTGTGGGAAAAAGTTCCCCCGCAGGGCGTCGCTGTTGCAGCATGCAGCGGCCCACAAAAAGGTGCACAACCCGACCACGTTTGACTGTGAGGTGTGCGGTATTTCCCTGGCCGCTCGCGTAGCGCTCGAGAAACATCGGTGGCGGGTGCACGGCGAGCAGAAGAACAACATGAACGTGATCAGCAACCTCGATCTGCGGAACGTTACGATTTTACCAACCGCCGACAACCGGTACCTGGAGCTTGACGTGCCGGACACTATATCGGAAGATTACGAACACGAAGATTAA
Protein Sequence: MKCFVSGCDTDDNVVSYTSVFYVNCPTDPTIQQQWFTLLEVTDPDAMRALVDGRSKVCSCHFTEDCFGHHPVYGYRYLLATALPTVFPPRKEIEQPKPDSAELEKDPALDYFLVYLDDPPGPAFIDQVALAGVTSGLDVIGNNTPLEVKPEQEQATIQEDDAELQEESNDVVTIEDEDGEDDDAIEQIGIEYANGKYYFLKLDDEPAPVGDVLVSAEEPNGNELEFRNSENATSTDADQEKSLHDLNENLQQLDKFVSQQDVGEADEYDEYEMDVSDQETEQFAGKQVHLETVEERSDTDVIEVKDDTEVDVVKEEYEVTSSKDTDSDSETGGDDNDYDCDALSEADYGPIEALEEVSVCGDKVRIRDENEGLNRFFCEYCGRGFRFKSLKDRHTLVHTKMKKFCCEVCGRGFTQKINLTIHLRTHTGESGNKKFTCQICGKKCIRMSELEAHMTAHLRKFPHVCPLCQERYSDATGLYDHFQVEHRSEMTLRELIDLLSENENAIVISDKEAPSNIRRDDGSYECPVCSKTYRMEANLERHKRKMHVKIYNCPHCPRKFLYKSLLHKHLPSHTLEKPYQCPHCALSYTQRVNLRVHMERKHAQQLKQPKKEPKAASEPSFVVATLNADGDVVESIETAQSPAPPPPPPRITGPRTHDCEECGKKFPRRASLLQHAAAHKKVHNPTTFDCEVCGISLAARVALEKHRWRVHGEQKNNMNVISNLDLRNVTILPTADNRYLELDVPDTISEDYEHED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093642; iTF_00095692; iTF_00104428; iTF_00101135; iTF_00101009; iTF_00107157; iTF_00107030; iTF_00104568; iTF_00093499;
90% Identity: iTF_00093642; iTF_00095692; iTF_00104428; iTF_00104568; iTF_00093499; iTF_00101009; iTF_00101135; iTF_00107030; iTF_00107157;
80% Identity: iTF_00095692;