Basic Information

Gene Symbol
-
Assembly
GCA_016097175.1
Location
CM027928.1:56338303-56355791[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 3.5e-05 0.0018 18.3 3.3 2 23 365 386 364 386 0.97
2 9 0.017 0.88 9.8 0.2 1 23 392 416 392 416 0.97
3 9 2.4e-05 0.0013 18.8 2.2 1 23 422 444 422 444 0.98
4 9 0.00017 0.009 16.1 0.5 1 23 450 472 450 472 0.98
5 9 2.8e-05 0.0015 18.6 2.3 1 23 478 500 478 501 0.94
6 9 8.4e-09 4.4e-07 29.7 0.6 1 23 511 533 511 533 0.98
7 9 0.0027 0.14 12.4 0.4 1 23 539 561 539 561 0.98
8 9 4.1e-05 0.0022 18.1 1.1 1 23 567 589 567 589 0.98
9 9 5.1e-06 0.00026 20.9 0.1 1 23 595 617 595 617 0.97

Sequence Information

Coding Sequence
ATGAACAACGTTTTATGCAGATTATGCTTAATGAAGTGTGAAGAATTGTTCGGAATGTACATCACCTCACCGAGCGGTGTGCAGCGCAGTCTGTCGAAAATCATACGAGAATGCGTCTCCATCGAGGTATCCGAGTTGGAGCCAAGCTATGTCTCCAAATTCATATGCAACGGGTGCGTCTACAAGCTGGAACAGTTTTACGCCTTTCGGCAGCAGAGTCTCAAGTGTCAGGAGTATTACAATGGACTGCTGCAATATTATCAGCAGTCGATCCCTTGCTCCAGTAAAACTACGTTAGACGCTACTGCAGTAGTAGTGCAGATGCCGGAATCCGTCGATAGCGTATTCGAAAGTCATCAACAGATTCAACCGGATCAGTCGATCCATTCGAGCAACGAGCTGGCCGACATAAACTTTTCCGCAAATGAGTTTATGATGGATGAGTCGGAAAAGAATCAGCTCAGCAAGGATTACGACGATATCATTCGTAGCTTGCAGAAGGATGACCTCGATTTTACGACCAACGACGATGAGCTCGTGATAAAACATGAATTAGAAATCTCAATACCGACAAATGGAGCAAGAATACTCAAAAACGACTTACTACAGCAGGAATGCACAAACTATTTGCAACCTCATGATGCTGTTCCGATGAATGTGGCACAAGCAACGGAACCGAATGAAAGCTGTTTCAATGCGTACACTACAATGGCGGTACCGTGTGGTGAGGATATAATGAATAGCGGCAGAACACTGCCAGTGGAACAGGAGGATGACTTAAGTTATGACGATTTTGTTGGCATTCCAACAACAACGCTAGAAGATCATCAAGAAATGTCATTGTCCGAAGCGCACGTGCAGGAAATAATCGCGGACGTCTATAATGCCACAGCAGAGAAGCAGTTACAATCAGCTGAAGAACTTCCCTCTCCGCAACAAATCTCCGGCGACGTACAGTGTAGTGAAATTTCGGGCCTTCAACCTAGCGATTCCTATTTCTCAATGGTTGACTTTGACGAGTCGGACGCAGCGGGCGTTGCCACCAGCAGCACCACCACTGTGAACGAGGCAAAAGATTTGCCAAACGATAAAACGTGCGAGATTTGTTTTAAGACGTTTCGCACCCGCCAGAAGCTGACGGTGCACAGAAATACGCACCTGCGGCTGGCACCGTTCAAGTGTACGTTCGAAGGATGCGCCAAAGCGTTCAAATCACGCATCGGGCTCGATGAGCATGTGGCTCGGCACACAAACAGCTTCGAATATACGTGCGACATCTGCTCGAAAGGTTTCCAGCACCGCAGCTACCTTTCCGCTCACCGGCGGGCGCACAACACGGAGCGAAACTTCCAGTGTGGACTGTGTGGGCAATCGTTCAAGGCGAAGCAAGCGCTACTAGATCACAAAAATCGACATCTCGGCGTGAAACCGTTCGCTTGTGAGCAGTGCGACAAGCAGTACACGAAGAACTCGCTGCTGCAGTCGCATATTCAGCAACATCATGGCAAGCGGGATGAAGCGATAACGCGCTATCCTTGCTCGGAGTGCGGGAAACAGTTCACTTCCAAAAGCTATCTCAACGTGCACATGCGAATACATCGAAATGAGCGACCGTTCGTTTGTGAGGTCTGTAATAAGGGTCACATTACACGGAAAGATCTCGCCGTGCACATGCTGAGCCACACGGGCGAGAAACCCCACACGTGCGAGTTTTGCGGCAAAGCCTACGCACGACGCAATGCCTTAGACTGGCATCGCCGGTCACACACTAAGGAACGTCCTTACATCTGTGATATCTGTGGTCAAACGTTTTCCCAGCCAACACCGTTACAGGTTCACCGGAAGCTACACGATACAGCAGATCGTAAAAAGCAGTTGCCCATCGAGGAACAACAACAACAGTTGGCCACCGAAGCAGCACAAGATCAAACCCGATAG
Protein Sequence
MNNVLCRLCLMKCEELFGMYITSPSGVQRSLSKIIRECVSIEVSELEPSYVSKFICNGCVYKLEQFYAFRQQSLKCQEYYNGLLQYYQQSIPCSSKTTLDATAVVVQMPESVDSVFESHQQIQPDQSIHSSNELADINFSANEFMMDESEKNQLSKDYDDIIRSLQKDDLDFTTNDDELVIKHELEISIPTNGARILKNDLLQQECTNYLQPHDAVPMNVAQATEPNESCFNAYTTMAVPCGEDIMNSGRTLPVEQEDDLSYDDFVGIPTTTLEDHQEMSLSEAHVQEIIADVYNATAEKQLQSAEELPSPQQISGDVQCSEISGLQPSDSYFSMVDFDESDAAGVATSSTTTVNEAKDLPNDKTCEICFKTFRTRQKLTVHRNTHLRLAPFKCTFEGCAKAFKSRIGLDEHVARHTNSFEYTCDICSKGFQHRSYLSAHRRAHNTERNFQCGLCGQSFKAKQALLDHKNRHLGVKPFACEQCDKQYTKNSLLQSHIQQHHGKRDEAITRYPCSECGKQFTSKSYLNVHMRIHRNERPFVCEVCNKGHITRKDLAVHMLSHTGEKPHTCEFCGKAYARRNALDWHRRSHTKERPYICDICGQTFSQPTPLQVHRKLHDTADRKKQLPIEEQQQQLATEAAQDQTR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00102523;
90% Identity
iTF_00093624;
80% Identity
iTF_00101117;