Acol007859.1
Basic Information
- Insect
- Anopheles coluzzii
- Gene Symbol
- wdn
- Assembly
- GCA_016097175.1
- Location
- CM027928.1:6149678-6156253[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00076 0.04 14.1 1.5 2 22 113 133 112 133 0.96 2 10 0.0043 0.22 11.7 0.9 1 23 141 163 141 163 0.95 3 10 1.4e-07 7.6e-06 25.8 3.3 1 23 169 191 169 191 0.98 4 10 0.00017 0.0088 16.1 0.1 2 23 220 242 219 242 0.96 5 10 0.043 2.2 8.6 0.1 2 23 250 270 249 270 0.93 6 10 8.4e-07 4.4e-05 23.4 3.8 1 23 276 298 276 298 0.98 7 10 6.4e-06 0.00033 20.6 4.4 1 23 304 326 304 326 0.98 8 10 0.00028 0.014 15.5 4.3 1 23 332 354 332 354 0.96 9 10 0.00031 0.016 15.3 1.0 1 23 360 382 360 382 0.97 10 10 4.4e-05 0.0023 18.0 3.0 1 23 388 411 388 411 0.98
Sequence Information
- Coding Sequence
- ATGCACCTTTTGGGCAAACACACCATGGAAGATGCGGTTACGGTGAAGTGCCCGCCGGAAATATCGCACGAAGAACGGAAAGAGTCGCCCCCGCGAGGACCTAAAACGGCAACACAGGATGAGAAAGTGAAGAAAAGCGTTGTCAATGGTAGCAGCAAGCAAAAGGAACTCGTTGGTGGCAATGACTTGAAGCTGGTGATGGAACCGCAAAACCCTTCCCCCACCAAGTATTTCGACACGAACGGCGTACCGCTGCGCAAGGCGGTAGAGGAAGGGAACTTCGAGCAAACGGCGGACAGGGAAGGGCTCGATAAGAAGCCGAGCAAAGTGACCATCAAATGCTGTAACTGTGAGAAAACGTTTACCTCTCGTGCGGCGTATGAACTGCACTATCGCACCAACTATCAACAGGAACCGGTTTACGAGTGTCCGGTGTGCGACAAGCGCATCAAACAGTACCGGGCGTACCAGCTGCATAGCTACCGGCACAGCGCCAACCAGCGCTTTACCTGTCCCGAGTGCTCCAAAACGTTCCACCAAAAGTCTGATCTCACGCGCCACCAAAACATCCACCAGCCCCCTGGCAGCAACGGTTCCGGCACGTCCAAGGAGCGCAATGCGGCAAAGAATGGCGGCGATGGAAACGAGCAAGTCATACCCTGCCCCCGCTGTGATGCCACCTTTGCTACGCAGGCCGAATTCAAGGAACATTCCCGAAAGCTTCATCGCACACCAAAGCAGCTGGTCGAGTGTCCGGACTGTGGAAAATTGCTTTCCACCGGTAGCCTCTACTCGCACCGTAAAATACACTCCGAAAGCCCAAAGTTCTCGTGCCCCGAGTGTGACCGCACGTTCGTGCAGAAGATCAACCTCATTCATCACCACAAAACGCACCTCACCGAGCGGCCCTTCCAGTGCGGCCAGTGTGATAAAGCGTTCTGCGAAAAGGCACACCTGCAGCGGCACCTCAACTACCACTCCCAGGAGCGGCCCTACCGCTGTGAGCTGTGCGGCAAGTGCTACAAAACGGAGCGCTGCCTCAAGGTGCACTCCGCCGTCCACAACAACGAGCGGCCGTTCGTGTGCACCGAGTGCAACAAAGGCTTTCTCAGCAGCTCCAAGCTGCGGCAGCACAGCAACATCCACTCGGGGCTGCGGCCGTTCAAGTGCAAATATTGTACGCGCGATTTCACCAACTTCCCGAACTGGCTGAAGCACATCCGTCGCCGGCACAAGGTGGACCACCGGACCGGCGAAAAGCTGGACAGTGTGCCGAAGTTTATGACGAAGAAAAAGCTACCCGTCGATCGGGGGTGCGCAAGAAGGAGCAACCGCCGGCCCTGCCCGAAGCGAGCGTAA
- Protein Sequence
- MHLLGKHTMEDAVTVKCPPEISHEERKESPPRGPKTATQDEKVKKSVVNGSSKQKELVGGNDLKLVMEPQNPSPTKYFDTNGVPLRKAVEEGNFEQTADREGLDKKPSKVTIKCCNCEKTFTSRAAYELHYRTNYQQEPVYECPVCDKRIKQYRAYQLHSYRHSANQRFTCPECSKTFHQKSDLTRHQNIHQPPGSNGSGTSKERNAAKNGGDGNEQVIPCPRCDATFATQAEFKEHSRKLHRTPKQLVECPDCGKLLSTGSLYSHRKIHSESPKFSCPECDRTFVQKINLIHHHKTHLTERPFQCGQCDKAFCEKAHLQRHLNYHSQERPYRCELCGKCYKTERCLKVHSAVHNNERPFVCTECNKGFLSSSKLRQHSNIHSGLRPFKCKYCTRDFTNFPNWLKHIRRRHKVDHRTGEKLDSVPKFMTKKKLPVDRGCARRSNRRPCPKRA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -