Acol011070.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles coluzzii
Gene Symbol
ZNF219
Assembly
GCA_016097175.1
Location
CM027929.1:19973263-19976655[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 1.3e-06 6.7e-05 22.8 2.6 1 23 96 118 96 118 0.99
2 12 0.011 0.58 10.4 0.5 1 23 124 147 124 147 0.98
3 12 0.0073 0.38 11.0 0.2 1 23 167 190 167 190 0.93
4 12 0.014 0.74 10.1 3.4 1 23 196 219 196 219 0.94
5 12 2.3e-05 0.0012 18.9 0.2 1 23 398 420 398 420 0.98
6 12 2e-05 0.0011 19.0 0.7 1 23 426 448 426 448 0.99
7 12 0.0072 0.38 11.0 2.5 1 23 540 562 540 562 0.98
8 12 4.6e-06 0.00024 21.0 0.6 1 23 568 590 568 590 0.99
9 12 0.00011 0.0058 16.7 0.0 1 23 657 679 657 679 0.95
10 12 0.00071 0.037 14.2 3.4 1 22 685 706 685 709 0.90
11 12 3.6e-07 1.9e-05 24.5 0.8 1 23 751 773 751 773 0.99
12 12 8.2e-05 0.0043 17.1 4.0 1 21 779 799 779 801 0.94

Sequence Information

Coding Sequence
ATGGAGCTGAAGGCGGAGAAAAAAGACCACAACGACCACGATGAAAGCGGCGGTGGTGTACGGCGACACGCTGCAGCAGCAGCTGCATCGGTCGCGATGGATGTCGAGGCGGCAGCGAATGGGGGCGAACAGTCGTCGGATCAGGAGATAGTGGAGGTCGGCATTGACGAGGATCACATCAAGTTTCTCACCAGCATGCACTCGGGCGACGAGGAGCCGTCGAACGGGGGGCACCACCAGCGCATGACGGCACAGAGGTCATCGTTGCTTGCCACAGAACGCACGTACCAGTGTGACGTGTGCCCGCGGATCTTTCACCGGCCGGACCATCTGCGCTACCACATGCGCATCCACGAGAAGAACAACCCGTTCGAGTGCAAGCTGTGCTTTAGCGTGTTCGCGTCCGATCCCGCCTTTGCGCACCACATCCGGACGGAGCATGCGGGGATGGGGCTGGCCGACGCGTTGCCCCCGGTGCCGGAAACGGAGGCGAACTACTTCGCCTGCACGTACTGCGACAAAGCGTACGGCGACGGGGTCGAGCTGGAGGAGCACCTGCACCAGCAGCATTTGGGCGAGCGGCCGTACAAGTGCAACATGTGCCCGAAAGCGTTCATCCGGATGGATTTCCTGCAGTGCCACTACCTGAAGTACCACAGCTTCCACCCGATGGAGGACGAGGAGGACGAGGAGGGGGGCGGTGAGGGCGAGGAGGAGGAGGAGGAGGATGGGGAAGAGGAGGAGGAGGGAAACAGTTACGGGCGGATGCAGCAGCAGCACCATCAAGCGGACGCGAACCAGCAGTACGAGCATCGTGCCAAGCGGCCCCGCTTGATGGTGCGCAAGATCGAGGATTTGGTGGACGACCGGGGCAGCAGTGCGGCGCTGAAGGGCCGGTTTGGGGCGGTGTCGCGGCGCACCTCGCACACCGGCACGAGCATTTCGAGTGACGATCGGCGCGACGACGACGATGACGATGAGGATGGCGACGATGAGGGCACGGGAGCGGACAGCAGCGATCAGCACCAGCGGTTCCTGCAGCGAAGGGAGGGCGGGTCGGTGGGCGGTGGGCGTAGCCTGCTGCCGAGGCTGAGCGGGGTGCATGGCCGGTTTTTGGCCGCGATGGAGGAGCAACATTCGAAGCGGCTGGCGGCAGCAGCGGCGGCGGCGGCGGTGGAAGAGAGCGCCAAGCATCGGTGTCCGGTGTGTGATCGAGGGTTTGCCCGCGAACCGGAACTGATGCTGCACGTGCGATCGCATCCTGATTTGCCCACCTTCAAGTGTCCGCTGTGCGAGCTGACCTTCATCGGGTCGGACTATCTGAAGAATCATCTGAAAAAGCACGTGATCGGCAACGGGGAAGATCCGGGCGCACCGGGTGCGATCGATTTGAAGGTAAACCCTGCCGCCGACACGAAACCGACCGCCCGGCAACCGCCCGCTGGCGATGGTGGCCCGTCCCAGACCACGCTCCTGCCCTCCACCGCCAAGCTGCCCAAACCGATCATCACGTCCAAGCCGCCCTCGACCGGCATCTCGCTGCTGAAACCGATCGAGGAGCGCAAACCGCCCGACCACCACCAGCAGGAGTACTGCGTGAAGACGCCCGACGGCAAGTTCATGTGCACGGTGTGCGAGCGGCTCTTCTCGCACCAGCAGACGGTGCGCATCCACTTCCGCATCCACACGAACGAGAAGCCGTACAAGTGCGCCTTCTGCGACGAGTCGTACATCCGGTCGGACTATCTCGAGCGCCATCTGAAGGTGCACTTTAAGGATGGGATGCTGCCGGCGGCCGCCATCGCGAGCATGGCGGCGGCAGCCGCAGCGGAGGATTTGGCGTACGCGGAGTCGAGTCCCTCCACGCCGGCGGCTGCTGGTACGGGGGGCTCCACCGGCAAACCGCTGATCGGGCGGGCCGGGCTGGCGCCGGAAAACTACCACTTTACCGAGTCGAACGACGGGCAGTTTGTGTGCAAGATCTGCGACGCCGTGTTCAGCCAGGTGGCCTTACTGCGCAAGCACGCGCTAGCGCACACGGAGGAGAAACCGTTCCACTGCGACATCTGCGACCGGTCGTTCAACCGGGTCGACTACCTGAAGGAACACTTCAAATCGAAGCGCCACCTGCAGCTGGTGGCGGAGGCGGCGGCCGCCGGCGGGGGTGCTGACGGGGTGGTCGAACCGGCGTCCCGGTCGGCGCTGGGTGAGTTCCATCGGTCCGATTACGAGCGCACGAGCGACGGGCGGTACAAGTGCAACCAGTGCGACAAGACGTTCGTGACGGCCGTCACGCTGAAGATGCACATCCGGCTGCACACGGGCGAGAAGCCGTACAAGTGCGACAAGTGCGATAAGGCGTTCATCCGCTCGGACTATCTGAAGACGCACGAGAAGTGCCACCGGCAGGAATCGTTCCTCAGCATGCTGTCGCTGACGACGTCCAAGGAACCGAGCACCGCGTCCTGA
Protein Sequence
MELKAEKKDHNDHDESGGGVRRHAAAAAASVAMDVEAAANGGEQSSDQEIVEVGIDEDHIKFLTSMHSGDEEPSNGGHHQRMTAQRSSLLATERTYQCDVCPRIFHRPDHLRYHMRIHEKNNPFECKLCFSVFASDPAFAHHIRTEHAGMGLADALPPVPETEANYFACTYCDKAYGDGVELEEHLHQQHLGERPYKCNMCPKAFIRMDFLQCHYLKYHSFHPMEDEEDEEGGGEGEEEEEEDGEEEEEGNSYGRMQQQHHQADANQQYEHRAKRPRLMVRKIEDLVDDRGSSAALKGRFGAVSRRTSHTGTSISSDDRRDDDDDDEDGDDEGTGADSSDQHQRFLQRREGGSVGGGRSLLPRLSGVHGRFLAAMEEQHSKRLAAAAAAAAVEESAKHRCPVCDRGFAREPELMLHVRSHPDLPTFKCPLCELTFIGSDYLKNHLKKHVIGNGEDPGAPGAIDLKVNPAADTKPTARQPPAGDGGPSQTTLLPSTAKLPKPIITSKPPSTGISLLKPIEERKPPDHHQQEYCVKTPDGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCAFCDESYIRSDYLERHLKVHFKDGMLPAAAIASMAAAAAAEDLAYAESSPSTPAAAGTGGSTGKPLIGRAGLAPENYHFTESNDGQFVCKICDAVFSQVALLRKHALAHTEEKPFHCDICDRSFNRVDYLKEHFKSKRHLQLVAEAAAAGGGADGVVEPASRSALGEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKCHRQESFLSMLSLTTSKEPSTAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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