Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027929.1:24980506-24985466[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 7.6 4e+02 1.5 3.3 3 23 234 251 233 251 0.87

2 17 9.5e-07 5e-05 23.2 0.2 1 23 257 280 257 280 0.97

3 17 5.4e-06 0.00028 20.8 0.7 2 23 287 309 286 309 0.95

4 17 0.0011 0.057 13.6 1.5 1 23 315 338 315 338 0.96

5 17 0.0003 0.016 15.3 0.5 2 23 345 366 344 366 0.96

6 17 0.013 0.66 10.2 1.0 1 23 372 394 372 394 0.92

7 17 1.4e-05 0.00075 19.5 2.2 1 23 399 422 399 422 0.97

8 17 0.42 22 5.4 1.0 5 23 635 653 633 653 0.84

9 17 0.00052 0.027 14.6 0.4 1 23 659 682 659 682 0.98

10 17 0.00074 0.039 14.1 0.4 2 23 689 711 688 711 0.95

11 17 0.0083 0.44 10.8 6.3 1 23 716 738 716 739 0.96

12 17 0.00079 0.041 14.0 0.1 1 23 775 798 775 798 0.97

13 17 0.01 0.53 10.5 1.2 2 23 805 827 804 827 0.96

14 17 0.00018 0.0097 16.0 3.1 1 23 833 856 833 856 0.96

15 17 0.00012 0.0065 16.5 0.2 1 23 862 884 862 884 0.98

16 17 0.00054 0.028 14.6 3.5 1 23 890 912 890 912 0.98

17 17 4.1e-05 0.0021 18.1 0.8 1 23 917 940 917 940 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	7.6	4e+02	1.5	3.3	3	23	234	251	233	251	0.87
2	17	9.5e-07	5e-05	23.2	0.2	1	23	257	280	257	280	0.97
3	17	5.4e-06	0.00028	20.8	0.7	2	23	287	309	286	309	0.95
4	17	0.0011	0.057	13.6	1.5	1	23	315	338	315	338	0.96
5	17	0.0003	0.016	15.3	0.5	2	23	345	366	344	366	0.96
6	17	0.013	0.66	10.2	1.0	1	23	372	394	372	394	0.92
7	17	1.4e-05	0.00075	19.5	2.2	1	23	399	422	399	422	0.97
8	17	0.42	22	5.4	1.0	5	23	635	653	633	653	0.84
9	17	0.00052	0.027	14.6	0.4	1	23	659	682	659	682	0.98
10	17	0.00074	0.039	14.1	0.4	2	23	689	711	688	711	0.95
11	17	0.0083	0.44	10.8	6.3	1	23	716	738	716	739	0.96
12	17	0.00079	0.041	14.0	0.1	1	23	775	798	775	798	0.97
13	17	0.01	0.53	10.5	1.2	2	23	805	827	804	827	0.96
14	17	0.00018	0.0097	16.0	3.1	1	23	833	856	833	856	0.96
15	17	0.00012	0.0065	16.5	0.2	1	23	862	884	862	884	0.98
16	17	0.00054	0.028	14.6	3.5	1	23	890	912	890	912	0.98
17	17	4.1e-05	0.0021	18.1	0.8	1	23	917	940	917	940	0.96

Sequence Information

Coding Sequence: ATGACCAGTTTTGTGCGTGTAATTGATAAAATTTGTAGATTCTGCTTATCGGAAAATGAAGCAATTCTACTGCCAACATCACAGGTCATCGATTCAACACTGACCGTCGATGATATTGAGCGATGTACCGGCGTACGGGTGGAGGAGGAAAACGTGTCGTACGTGATATGCGAACCGTGCCACAACAAGCTGCAAAAATTTACCGCCTACCGTTACTTCTGCTTAAGCAATGACGAGCGCTTCCGGGAACTGTTTTCAGCGCTGTGCGCAAGTGAGCGAGATTCGGAGGCTAAACCACCGAGTGCGATGTCCGAACACAGCTACTTCCGAATGGACGATGACAGTGAGTACGTGATTAGCTACGCCAAACCCTCGGATGACGATTATGAAGAAGCAATCGAGGCCTTTGGGCTCGAGGAACATCTAGAGCCGGAAGAGCATGTTGAAATACTCGAACCAACGGAGCAGCAGAACAGTGACGAGGGATTGGACTGGTGGTCCGCCACTACACCACCATCACCGTCCGAAGCCGAACCTTTCACAGAGGAGCTGGAAGAGATTGAGCCTCCGGTGAAACCAAAGAAACCACGGAAACCGTACGTGCGACGGGCGACGATTGGTAAAGAGCAGGATAGTTCGGTGAAAAAACCACGGGTGTATAAGAAGCGACCAAATCGAAACAAGCTGCCCAAGAAGCTGTGCACGGTGTGTGGTAAGTTTGTGGCCCACTTGAACCATCACCTTCTATCGCACACAAAGGAACGAAGGTTCCCTTGCACATACTGTCCGAGGGCTTTCAGTCGCAGCTCGTTATTGAAGGTGCACGTAGAAACGGTACATCTGAAGAAGACGGCCAAGAGCTGTGAGCTGTGCGATAGGAGCTTTTCGTACAAATCCAGCTACACGATCCACATGCGAGCTGCACATGATATTGGCGAATGGTACGAATGCAAGCTTTGCGATCTGAAGTTTCGCCATCCGGGAGGCTTGCGGGGTCACAACAATCGCAAGCACAATGTGGCGAGCAACTGCGAATGCACAATCTGTGGCATGATCTTTCAGGACAATATTGGACTGAAGAAACATGGCCGAGTGCACTCGAACGAACAACCGTTTGCGTGTCGCTACTGTCCGAAGCGTTTCAAAAGCCCGAACGCTCACCGGGCACACGAGCTGATCCACCAGGGTGTTGTGTTCACGTGTGAGTACTGTGAGAAAACCTATCGGTACAAATCGCTGCTCAATATGCATGTGAAAAAAGAGCACAAGAAGCAGGTGGCGAAAAACGATGAGGCGCTCTTTCCCGTGTCCAGCATCATCGATCCCTCGCTAACGGATGTAGATATAGAGCGTTTCACCGGGATACAGCTGTTTGGCGAAGAATGTATATCGTACTCGATCTGTGTCGACTGTGGTAATAAGCTGAAAAAGTGCTCTTTATTCCGTGCGGCGTGTTTAAACAATGACACGCTGTTCAAGCAACTGTTTGCGGTGCTGCTCGAAAGTGCCAGGAAGGAAACATTGGGCGGAGAAAATCGCGATAAAAAGGAGGAAGCGGTGGAACAGCACGAGGAAGAAATCGTGGAAGAGTTCGCGCTGGTCGAGGCAAGCGAACATTTGGAGCAGCTGATCGAGCAAGCGGAAGATGTTGAGATCGAAACGCAAGAGCTGTCCGGGGAAGAAGACGAGGAAACCGCCAGCAGTGACGAGATGGAAGACGGCTCGCAGGAAAACGCCGAAAGCGGCGACGAGTCTGGGACGAACAATTTGCTGGATGAAAGCACCGACAGTGTAGAAAATAGTCCGCCAGCTCGTACGAGGCGGCTGTCCTCGCGGTCAGCCAGAAGCGCTCAAACGAGCGACGCAACCCGCTCACGGAGGAAGGCAGACCACCACTATCAGCATTGCGATGCGTGCGGGAAGATGGTGTCGGATCTGAAAAGTCACATGCTAAGCCACACGAAGGAGAAACGGTTCTCCTGCCCGTACTGTGCCGTGACGATGACGTTCAAGTCGAATCTAAACATCCATATCAAGACGGTCCATTTGAAGGAGATTTCGAAATCGTGCGAGCTGTGCGGGCAAGGATTCGTCAATTACAATTCCTACAAGAACCATATGGCCTCGCAGCACGGAACGGGTGAGTACAGCTGTGAAACGTGTGCGAAAAGGTTTACGCATCTGCGAACGTACAACATGCACGTGCGCCGGCACCATAAAGCCGATGCGACGTACAAGAAAAAGAAGCAACTTTGTGGCACGTGCGGCGCCATGGTTACGCACATAGCGACGCACATGCTCACCCATACGCAGGAGAAGCGGTACGCCTGTCCGCACTGTCCGATCGAAATGGTGGACCGGGGGAATCTGATGCGCCATGTCCGGTCGGTCCATCTGCAGAGTGAGGTGAAGTCGTGCGAAACGTGCGGCATAGGCTTCAAGTATCCCAGCTCGCACAGATCTCACATGCTCCGAGTGCACGGCATTGGGAAAACGTTCGACTGCCACATGTGTGCCAAAAAGTTCAACCACAACAGTGGGCTTAAATCGCACATTGCCCGTGTGCACAGCAATGAGCGAAAGTTTGAGTGTGAAACGTGTGGGATGCTGTTTAAAGTGAAAGTCGCCCTTACGAAGCATCAGCTAGTGCACTCGACGGAGCAACCGTACGCGTGCAATCAATGTCCGAAACGGTTCAAAAGTCGCCATGGACGCAATTCACACCAACTGACCCACAGTGGCATAGTGTTTCCGTGTCCACACTGTGACAAATCGTACCGGTACAAAGATGTGCTTGGCATTCACATTCGGCAGAACCATCCCGAAGCAAAGGAGGAGAAGTCGATAGCGTGTGAATAA
Protein Sequence: MTSFVRVIDKICRFCLSENEAILLPTSQVIDSTLTVDDIERCTGVRVEEENVSYVICEPCHNKLQKFTAYRYFCLSNDERFRELFSALCASERDSEAKPPSAMSEHSYFRMDDDSEYVISYAKPSDDDYEEAIEAFGLEEHLEPEEHVEILEPTEQQNSDEGLDWWSATTPPSPSEAEPFTEELEEIEPPVKPKKPRKPYVRRATIGKEQDSSVKKPRVYKKRPNRNKLPKKLCTVCGKFVAHLNHHLLSHTKERRFPCTYCPRAFSRSSLLKVHVETVHLKKTAKSCELCDRSFSYKSSYTIHMRAAHDIGEWYECKLCDLKFRHPGGLRGHNNRKHNVASNCECTICGMIFQDNIGLKKHGRVHSNEQPFACRYCPKRFKSPNAHRAHELIHQGVVFTCEYCEKTYRYKSLLNMHVKKEHKKQVAKNDEALFPVSSIIDPSLTDVDIERFTGIQLFGEECISYSICVDCGNKLKKCSLFRAACLNNDTLFKQLFAVLLESARKETLGGENRDKKEEAVEQHEEEIVEEFALVEASEHLEQLIEQAEDVEIETQELSGEEDEETASSDEMEDGSQENAESGDESGTNNLLDESTDSVENSPPARTRRLSSRSARSAQTSDATRSRRKADHHYQHCDACGKMVSDLKSHMLSHTKEKRFSCPYCAVTMTFKSNLNIHIKTVHLKEISKSCELCGQGFVNYNSYKNHMASQHGTGEYSCETCAKRFTHLRTYNMHVRRHHKADATYKKKKQLCGTCGAMVTHIATHMLTHTQEKRYACPHCPIEMVDRGNLMRHVRSVHLQSEVKSCETCGIGFKYPSSHRSHMLRVHGIGKTFDCHMCAKKFNHNSGLKSHIARVHSNERKFECETCGMLFKVKVALTKHQLVHSTEQPYACNQCPKRFKSRHGRNSHQLTHSGIVFPCPHCDKSYRYKDVLGIHIRQNHPEAKEEKSIACE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107128;
90% Identity: iTF_00107128;
80% Identity: -