Basic Information

Insect: Anopheles christyi
Gene Symbol: Bcl11b
Assembly: GCA_000349165.1
Location: KB700348:16817-18962[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.3 1.4e+02 2.5 2.8 1 21 282 302 282 303 0.91

2 11 0.013 0.78 9.6 0.3 1 11 320 330 320 333 0.92

3 11 8.5 5.2e+02 0.8 0.0 1 20 348 367 348 369 0.80

4 11 0.00033 0.02 14.6 0.3 1 21 432 452 432 453 0.93

5 11 8.1 5e+02 0.8 1.4 1 21 460 480 460 484 0.84

6 11 2.1e-05 0.0013 18.4 0.6 1 23 510 534 510 534 0.93

7 11 0.04 2.5 8.1 0.1 1 20 558 577 558 579 0.94

8 11 0.0036 0.22 11.4 0.1 1 23 587 609 587 609 0.97

9 11 0.00027 0.016 14.9 3.8 1 22 615 636 615 637 0.90

10 11 0.00011 0.0065 16.2 1.5 3 23 644 665 643 665 0.94

11 11 9.2e-05 0.0056 16.4 0.1 2 23 671 692 670 692 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.3	1.4e+02	2.5	2.8	1	21	282	302	282	303	0.91
2	11	0.013	0.78	9.6	0.3	1	11	320	330	320	333	0.92
3	11	8.5	5.2e+02	0.8	0.0	1	20	348	367	348	369	0.80
4	11	0.00033	0.02	14.6	0.3	1	21	432	452	432	453	0.93
5	11	8.1	5e+02	0.8	1.4	1	21	460	480	460	484	0.84
6	11	2.1e-05	0.0013	18.4	0.6	1	23	510	534	510	534	0.93
7	11	0.04	2.5	8.1	0.1	1	20	558	577	558	579	0.94
8	11	0.0036	0.22	11.4	0.1	1	23	587	609	587	609	0.97
9	11	0.00027	0.016	14.9	3.8	1	22	615	636	615	637	0.90
10	11	0.00011	0.0065	16.2	1.5	3	23	644	665	643	665	0.94
11	11	9.2e-05	0.0056	16.4	0.1	2	23	671	692	670	692	0.94

Sequence Information

Coding Sequence: ATGCAACCCAAACACTGTCGAATATGTTTCAAACCGGACAACGACGATCTAATATCAGTGCGGCTGAAGCAGGAAGGAGTTTCAATCGAGCAAATGATTTTCTCCATCAGTGGCATCTGCGTTACGAGTGATCGGCGTTTGCCACAGAACATTTGCCTCGAATGTTTGGATCGCTTGAAGGTGGCGTACGAGATACGGCAGCAATGCATCCGCATGAACGATTGGTTGTGCGAAAAATTATTGGTGTTAAAAGAGGATATTAAGGTGGAACACAGAGAAGAAGATGCACCTGAATCTAATGAAGCATCTGATGGAGGTGAAAAAATGGTTCAGAATTCGATTGCTTTTGAAGCCACCAGGTTGTATGAAGAAGAAATGGAACCAGAATCAAACAACGAACAGGAACCGCCAGAACACAGCGATGACGAGTGCAACGTTATGCAAGTGAATACCGATAGCCAATCAGAGGACGAAATTGAAGAATGTCTCGAAGGACTTGTAGAGGAACGATCTTCTTTACAGAAGCTTGAGATAGAGATCGATACAGGAGAACACGGGTCCGATACAAAAGAGCAGTATCTATTGTCTGAATTTAGCGGGGAAGAGGATGAACTGACGATAGAAGTGAATGCAAGTGAAAGATCGACCGTTGACATAGAGGGAGATTTAGATGGTCCATATCATGAATGCCCGTACGAAGAAGATTGGGAACAACAAGCGACTGAAAAAATGGCACAGCAATCACAAACAAATAAAATACAGCGAGCGATATGTCGTATTTCGGAGAACAATTTGCTCATACGTTCGGCGGAACAAGGATATAATATTGTGGAATTACGCCCTCACCGTTGTTGCTGCTGTGAGGAACTGTTCACCACCGAGGAAGAGCTGAATGAGCATTTGAAGGGGCGCGAGAATAAGGAAGATGTGAATGGTCAACCCGACCCTAGCGTGCGGTACGTTTGCGAGTACTGTGGAAAACACTTTAAGCTATGGTTGGTGTACATCTGCCACAAGCGCATGCGTGAACAGCGCCAGTTTTACCAGTGTCGACTATGCAATGTGCTACTCGATTCAGCAACTCGCATGATCTCGCACATGTTATTGTCCGAGCAGCACGCAAACTACTTCAATTTGTCGCGGGAAAGTATCGCCGATCGGTACACATCGATTGCCCTGCCCGGCGAACGGTGCTGCTGCTGTAAGAAGTATTTTGATCAGAACGAAAAGCGGCTAGAGCACGTGCAGCATGTGCATCGCTCGAGTACAGTCGACAAAACGGCCAATCCTTCACACGCTTGCGATGTGTGTGGGCGAAGGTTTATGAGTAAGGATCGGCTGAACGCTCATCTGCAGTACACGGTGAACGTTATGCAGCACTACTGCAAGCAGTGCGAATTTCAAACGTACAACCCAAGGCGCATGGAACTGCATCTGTACAGTGGCATTCATCGGGATGCTGACTTACCTGCGGCAATCGAACTAAAGCCGCTCGAAAACAACTTGCTGACGGGTAACCGATTACAGTACTGTTGTTTTGAAGGATGTAATAAACCATTTCCCAATCAATCAGCTCTGCGGCAACACATCCAGGAGGCACACCAGGACACGTTAGAGATGCATAAGGTTCAAGCGGAACGGATTAGCAATGCGGAAAATCTGGAAAAGTTCCATGAATGCAATAATTGCTACGCGATATTTAAAAGCCTGACCGGTCTGTATGCTCACCAAGGGGTACCAAAACGCACCCGGCAAGAGTTTGTATGCTCCGTGTGCGGTGTAAGCAAGCGGAGCCAATCTGATCTAGTTGTTCACGAACGAGCGCATACTGGTGAAAGGCCATTTCCCTGCGATCATTGCGATAAAACGTTCGCGTCCAAGAAAACGCTTGCCTCCCATTGTATCAGTCACCTTCCTAGGCAGAACGCGTGTGAGCTTTGTGGCGGAAGGTTTAATCGCAAGGAACATCTCACCCGCCACATTACGCTCAAGCACGGTACGGCAACGATTCCGTGCGATGTGTGTGGGAAAAAGTTTAAAACCATCGGAACGCTAAACATACACAAGGTGTCGCATACG
Protein Sequence: MQPKHCRICFKPDNDDLISVRLKQEGVSIEQMIFSISGICVTSDRRLPQNICLECLDRLKVAYEIRQQCIRMNDWLCEKLLVLKEDIKVEHREEDAPESNEASDGGEKMVQNSIAFEATRLYEEEMEPESNNEQEPPEHSDDECNVMQVNTDSQSEDEIEECLEGLVEERSSLQKLEIEIDTGEHGSDTKEQYLLSEFSGEEDELTIEVNASERSTVDIEGDLDGPYHECPYEEDWEQQATEKMAQQSQTNKIQRAICRISENNLLIRSAEQGYNIVELRPHRCCCCEELFTTEEELNEHLKGRENKEDVNGQPDPSVRYVCEYCGKHFKLWLVYICHKRMREQRQFYQCRLCNVLLDSATRMISHMLLSEQHANYFNLSRESIADRYTSIALPGERCCCCKKYFDQNEKRLEHVQHVHRSSTVDKTANPSHACDVCGRRFMSKDRLNAHLQYTVNVMQHYCKQCEFQTYNPRRMELHLYSGIHRDADLPAAIELKPLENNLLTGNRLQYCCFEGCNKPFPNQSALRQHIQEAHQDTLEMHKVQAERISNAENLEKFHECNNCYAIFKSLTGLYAHQGVPKRTRQEFVCSVCGVSKRSQSDLVVHERAHTGERPFPCDHCDKTFASKKTLASHCISHLPRQNACELCGGRFNRKEHLTRHITLKHGTATIPCDVCGKKFKTIGTLNIHKVSHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -