Achr002635.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles christyi
Gene Symbol
L
Assembly
GCA_000349165.1
Location
KB685591:8641-14401[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.42 26 4.9 5.7 1 23 25 47 25 47 0.98
2 17 3.5e-06 0.00021 20.8 3.7 1 23 53 75 53 75 0.99
3 17 1.1e-05 0.00065 19.3 0.3 1 23 81 103 81 103 0.98
4 17 4.6 2.8e+02 1.6 0.1 2 23 202 225 201 225 0.78
5 17 0.052 3.2 7.7 0.1 2 23 275 297 274 297 0.96
6 17 0.15 9.1 6.3 0.2 1 23 605 627 605 627 0.95
7 17 4.2 2.6e+02 1.7 1.8 1 23 671 693 671 693 0.92
8 17 0.00023 0.014 15.1 0.2 1 23 739 762 739 762 0.93
9 17 0.0017 0.1 12.4 0.8 1 23 769 792 769 792 0.97
10 17 0.0017 0.11 12.4 1.5 1 23 824 846 824 847 0.96
11 17 0.3 18 5.3 0.2 1 23 1150 1174 1150 1174 0.91
12 17 0.00042 0.026 14.3 0.2 2 23 1183 1205 1182 1205 0.96
13 17 0.0031 0.19 11.6 0.1 1 23 1212 1234 1212 1234 0.98
14 17 1.6 98 3.0 1.2 2 20 1242 1260 1242 1263 0.94
15 17 0.0017 0.1 12.4 0.2 1 23 1451 1473 1451 1473 0.97
16 17 0.0086 0.53 10.2 0.1 1 20 1483 1502 1483 1506 0.95
17 17 0.026 1.6 8.7 0.3 1 23 1514 1536 1514 1536 0.95

Sequence Information

Coding Sequence
ATGGCGGTGTTTTGTGatattaattCTACACCATTATCGCCCCACTTCCAGAGCCACACGGAACACATGCCATTCAAATGTGAGTACTGTGCCCGACTGTTCAAGCATAAGCGCTCCCGCGATCGCCATACGAAGCTGCACACCGGTGATCGACGCTATCGCTGCCTGCACTGTGAAGCTGCATTCTCCCGCAGTGATCATCTAAAAATACACATGAAAACACACGATAACCAGAAACCGTTCCAGTGTACGATCTGTAATAGGGGGTATAATACGGCCGCTGCCCTAACGAGTCATATGCAGAATCACAAAAAGCAACTAGCACTCACCGGCAGCCCAAATCTAACGTACAGTCCGCGCTCAACTACAAGCTCTCTGTCCAGCggtggtggtggtggtggtggaagtggtggtagtggtAAGCGAGGCGCAAAGTTCTCTCCCTACTCCACCGATCCTCTGCTGCTGATGAGCCGTGGTAACTCCAAACTGTCCTCCTCCCTTGCGAAAGCCAGTTCCGGGAATGCTGCCAACAGTAATCGTACTCCAACGCCTGGAAGTACTGGCACGGCTGCAGCAGGTGGCCCCCATCAGGATCTGCTCTCCTGTCCATACTGTACGCGGACGGATTTCGGTACGCTCGAACAACTCGGCCTACACGTACAGTCGATGCATGGGCACGGTGGCGGCGGTGCTGGTGGTGCCTTAGGTTTGCTTGGTGCGGACACATCACTGCCCTACTTCACACCGGGTGGACGACGTGCGGTAACCCCCGATGGGAACGCTCTCTCACTCGGTGGTCTCAGCCCTTATCCACCGATCACCTGCGAGTTCTGTACGATGAAGTTCCCAACCGTGCCGCTTATGTTTGCCCATCTCAAGACAGCACATCTGGACCGGTTGGCTGGCGGTAGTCATCAGCGTTCCTCACCTTCAAATGGTAGCCCGCTGGGATCACGTCCACCCAGCAGTGGCTTTCATCCGCTGGATCAGCTACACTTTAACAAGAGCCTGCTCGGGAATGCGTTCCCTTCCTTCTACGGTGGAATGGGCGGTAACTCCAACAGTGCTGCTGCCGGAATGTCCGGTGGTAGTATGAAAGCATCGGAACATCGGACCTGCGGTGATGAAAATGGGAAGAACGATGTGGGCAGGAAGCGCAAGCGCAGGGAAGACGAGCATGCTAAGGAGCGTGACCGTGAGAGTGTGACCAAAAGGGACAAGCAGGAAGAACCATCACGGCCTCCTATCCAGGGTGAAGAGGAACAGGATAATGAGGGTGAAGACAGTGAACCTCGTGGTACGATTAATCGCAGTGAGTCCGTGGACGATACGAAATGCACACCACCGATTAAGCAGGAACGAAAGGAAGAACTGGAACATCCGGCAACATCACCGGCGACTTCAGCACGTTCGTCTCCTTGCTGTGATTCGTCGCTGGAATCGGGCAGCGTGCGTCCAAACAGTCACAGTCCGGCAGAACAGCTCACACCGACCGATCTTAGCCAGCCGAAGATGAAGCGACTCAAGCTGGAGATGCCCGAGGACGACGAATTGCACGATGGAGATAATAAGGCATCGCTGATACAGCCGTGCGGTCGATCTCATGTAGGCTCTCGCGAGCAGCAGAAGCAACGTAGCAGTGGTCCAGTAGCAAGCAGAAGAGACAGTGACTCAAAAGAGTCACACCTGTCCACACTACAGCACGCCTCCCTGGTGCACAGCGTTCAACACACGCAACCGATGGGTGCTTCTACTTCTTCTAACACAGGCTCATCATCGGCACAGCACGCTCAACCGCCGCCGGGGGCTTATCTTTGCAATCAGTGTAATGCCGCACTGCCCGACTTTGAATCGTTTCGCACACACCTTAAAGCACATCTCGAGCAGAGTGCGGCCAGTGCTGCGGCAGCAGCTGCAATGCGACTCTCTGGGGAGCACGGTATTGGGAGTTCATCCGGCAATGGTGCTACTACTGTCGCACAAGGTTCATCCCTTTCGCTCACGACCTTTCACTGTCAGCAGTGTGGAGCTACGCTGAGCTGTCAGGCAGAGTACGAACAGCACACGATCGGACATTTCCTTGTGATGGCGGTCGAGTATCGCTGTCAGGCGGCTGGTGGAACCGGTGGTACAAGCTGCAGTGGCAAGGGCACCTTTGGGAAGGTGGAAGATCTGCACAAACATCTGTACGAGGGTCATATGCAGCTACTGTACAAGTGCACCGTGTGTGGTGAAACGTTCGAGTCGAAGGTCCAGGTACAGGTACACTTTGCCGTGAGTCATTCGGTGGAGGTGAAACTGTACCGTTGTTCGGCCTGTGCGGAAGTGTTCCGATCGGAGCGTGATTTTCGGCAACACATTCGCAATCGCCACTTGACGGCGGGTGCCGTACAGTGTATGTTCTGCCGGATGGTTTGCTCGTCCGAGCTCGAGATGCACTTCCATCTTGCATCACACGCCCGGAAGTATAAATGTCCAGCCTGTCCCGAATCGTTCCACGTAGAGTTTCTGCTAGACCGACACATTCAAACGCACCACAGCCAGAAGGAAACAAACTCACCAAACCGAAGGGAGTCCACTGTAAACCATAACCTCTCATTGGTGGGCCAATCTACATCCTCTTCCTCTACTACCACCAACAATACCACCACATCCATCAACCCACCGCCGACACCCTCCTCTACCACCACAACAGCAGTATCGACGGTACCAACTTCAACCGTCACCGGATTGGACTACCTTCACCTGCACGGACAGATGGCGGCAATGGCAGCGGCTGCCGCATGGCCCAGTCTATATCAAACGGCCAACAAGTTCTACGGCAATCCACTGCAGGTGGACACACTGAATCAATTGAAGCATCCACAGCATCTACTGCACGGTTTCTACGACACAATGCTCGGCAAGGCGCAACAGCAGCAACGGGTTGGTGCATTCCTATCCGATCCTCCCAGCAGCACGGGTGGCAAGAAGCATCCTTTCGCTGGCCATTCACCAAACACTACCACTACTACTACCAATGCACTGCTTGGGCTGGGTTATGGCGCCACAGCAAATTCTCAACAGCAAAGAACAGCTGGATCTCACACACTTAACGGTACACCGTCCTCCGGATTGTACTCCCCCGAAGAGCCGTCCGGTGGGACGGGGTCGAATGTGCCCACCAACAACAGCTCGAAGCTTTACTCACCCATTGCCATGATACAGCGGTACGGAGATAGTGGGCTGTTACACACCACCGCCAGCACGACCCTTGGTACAGCGGCATCTAGCGGTGGTCCATCACGCGCGGAATCACCTACACCTCCGGGTGGGCAACTACTCGCCCTGCCGGAACACCATCCAGAGCAGACGGGGAATCGAAAGGCAATGCAACAGTCGGGCACAAAGCAGTCCGGCCCAGTAACACCACAACAAATCGTTGCGTCCAGTTCGAGCAGCTGTTATAGCTGCGGTATCTGCGAACGATCCGATTTCAGTACGGAAAGTGAGGTCCAAACGCATCGCAAGATTGTGCACAATCTAAAGACGGGCGTTAGCTTACGGTGCGCCTACTGTAACGGGGACTTCCGATCGAGGAATGAGCTGGAGAATCACATGAAGGTCGCCCACAATACGGGCGGTGGCAAGCACAAGTGTTTGATCTGTGATGAAATCTTCCCCTCACCGGCGGTACTGGCAGAACACAAGCTGACCCACTGTAAGGTGGGTGCGTCGGGTCGCTGTTCACACTGTAGTCTCCCGCTGCCGGACGCTCACACCTTCAAGCAGCATCTGCCGGCTCATCAGCAATCAGCAACCGGTGGATCATCCGGCACGACAGGAGGAGCAGCGACCAATGCCACTAACGGTGGTGGTACGTCAGGTAGCGTCATCTCCTCTGCCGGTCAGAATGCGTCTTCTTCGGCTGGGAGTAATACAACGACGACAAGTTCCGCTACCGATCAGGAACGATTCCCTCAGCAGTGCATCTGTTGCCGACAGACGCTTAATTCCGAGTTTGAAATTAGTCTTCATGCCAAATTCCACACCAAATCCCCCGACACTAACGAGCGCACGTGTGCCCTATGTCTGGAGCCACTGCCATCGCAACCCGAATCGAACACGAAAATTTGTGATCCCTGTCTGAAACGTCACAATTTCCCCTCGAAACTCCTATCGATGAACTTCCTCAAGCCTCCTGCAGCGTCTTCGCTAGTGCCAGCACCAAACCTCGGTGGACCATCGGCCGCTGTTGGATCCCAAACTCACGGTACAATGGGAAACAGTGGACCACTGGAAGGGGGAAGACCACCAACATCTACTACGATCCACCAACATCAGGATGGGCCAACCCCCGCAGGACTGTACCAGTGTAATCTCTGCAAGAAACCGTTACCATCGAGCCAAAAGCTTCAGGAACATCTGATCGAACACACGTTCGCTGGGTGTGAGGAGCGAGGTTACGTCTGCTACCTTTGCTCTGCCGTGTTCACCTCATCGGCCGGACTGCAGACACATCTGCCGCTGGCACATTCCAATGCGGCCGCCAAACCGTACGACTGTGAACGGTGTGGCGTGGCGTACTTCTTCCGGGCCGAACTCGAGCATCATCTGATTGATCATGAGCTAGGAACAACGGTGAGACCGACGTTTGAGCATTCGGACGTAAGGGGTGCTGGCGGTGCTGGTGACGAGTGGCACACAGCGCAGGGTTCCCCCCTGTCGGAAGATGACGATGATGACGGAAAGGGCCACATCAAGCAGGAACAGTGTGAACCAGAACAGGAACACGACGGATCCTCACCATATCCACAAAAAGGGGAAGATTCGGAAGAGGAAAATGAATATCAAGCTTCTAGAAATGAAGAggacgaggaagaagctgacatggaggagcaagaagaggacagggaACAGCCTCACACTGAGGGtgatgataatgggcaggcggaaaaggatgagaacgattgtgatgaggatgatgatgaggatgatgatgTAGCAGTAGGCGTTGATGAGCGTAACGAAGCAGCCGAAGTAGAAGGTGACGACGAGGAACAACACCGAGAACAGCAAGAGCAGgacgaagacgaagacgaagaGTACATTGAGGTGGAGCACACTACGATGGAGGATGGTGGAAGAGGCAAACCTAGCGACGAGCGTCTCCGCCGAGCATCAAACAACATGTTGATCAATGGTGGAAAGGATTGCTCAGTGCTGACTGCTACAACGGCAGCGACAACACTGCCGGTCGTAACTGCGGCTGAGTGA
Protein Sequence
MAVFCDINSTPLSPHFQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGGGGGSGGSGKRGAKFSPYSTDPLLLMSRGNSKLSSSLAKASSGNAANSNRTPTPGSTGTAAAGGPHQDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGGGGAGGALGLLGADTSLPYFTPGGRRAVTPDGNALSLGGLSPYPPITCEFCTMKFPTVPLMFAHLKTAHLDRLAGGSHQRSSPSNGSPLGSRPPSSGFHPLDQLHFNKSLLGNAFPSFYGGMGGNSNSAAAGMSGGSMKASEHRTCGDENGKNDVGRKRKRREDEHAKERDRESVTKRDKQEEPSRPPIQGEEEQDNEGEDSEPRGTINRSESVDDTKCTPPIKQERKEELEHPATSPATSARSSPCCDSSLESGSVRPNSHSPAEQLTPTDLSQPKMKRLKLEMPEDDELHDGDNKASLIQPCGRSHVGSREQQKQRSSGPVASRRDSDSKESHLSTLQHASLVHSVQHTQPMGASTSSNTGSSSAQHAQPPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAAAMRLSGEHGIGSSSGNGATTVAQGSSLSLTTFHCQQCGATLSCQAEYEQHTIGHFLVMAVEYRCQAAGGTGGTSCSGKGTFGKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEVFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETNSPNRRESTVNHNLSLVGQSTSSSSTTTNNTTTSINPPPTPSSTTTTAVSTVPTSTVTGLDYLHLHGQMAAMAAAAAWPSLYQTANKFYGNPLQVDTLNQLKHPQHLLHGFYDTMLGKAQQQQRVGAFLSDPPSSTGGKKHPFAGHSPNTTTTTTNALLGLGYGATANSQQQRTAGSHTLNGTPSSGLYSPEEPSGGTGSNVPTNNSSKLYSPIAMIQRYGDSGLLHTTASTTLGTAASSGGPSRAESPTPPGGQLLALPEHHPEQTGNRKAMQQSGTKQSGPVTPQQIVASSSSSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQSATGGSSGTTGGAATNATNGGGTSGSVISSAGQNASSSAGSNTTTTSSATDQERFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPESNTKICDPCLKRHNFPSKLLSMNFLKPPAASSLVPAPNLGGPSAAVGSQTHGTMGNSGPLEGGRPPTSTTIHQHQDGPTPAGLYQCNLCKKPLPSSQKLQEHLIEHTFAGCEERGYVCYLCSAVFTSSAGLQTHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGTTVRPTFEHSDVRGAGGAGDEWHTAQGSPLSEDDDDDGKGHIKQEQCEPEQEHDGSSPYPQKGEDSEEENEYQASRNEEDEEEADMEEQEEDREQPHTEGDDNGQAEKDENDCDEDDDEDDDVAVGVDERNEAAEVEGDDEEQHREQQEQDEDEDEEYIEVEHTTMEDGGRGKPSDERLRRASNNMLINGGKDCSVLTATTAATTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-