Achr000436.1
Basic Information
- Insect
- Anopheles christyi
- Gene Symbol
- -
- Assembly
- GCA_000349165.1
- Location
- KB675091:27923-34634[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.56 34 4.5 0.0 11 23 224 237 205 237 0.86 2 23 6.1e-05 0.0038 16.9 0.5 2 23 246 267 245 267 0.96 3 23 7.6e-05 0.0046 16.6 2.0 1 23 298 321 298 321 0.97 4 23 0.016 0.98 9.3 0.3 2 23 327 348 326 348 0.92 5 23 3.2e-06 0.0002 21.0 1.4 1 23 352 374 352 374 0.97 6 23 0.00014 0.0086 15.8 0.6 2 23 385 407 385 407 0.97 7 23 0.00014 0.0087 15.8 0.5 3 20 415 432 414 434 0.93 8 23 8.2e-07 5.1e-05 22.8 0.7 1 23 441 463 441 463 0.98 9 23 8.8e-06 0.00054 19.6 2.0 1 23 469 492 469 492 0.97 10 23 0.022 1.4 8.9 0.3 2 23 758 779 757 779 0.96 11 23 0.00011 0.0065 16.2 4.0 1 23 810 833 810 833 0.97 12 23 0.035 2.1 8.3 0.4 3 23 840 860 838 860 0.94 13 23 6.5e-05 0.004 16.9 2.2 1 23 864 886 864 886 0.97 14 23 0.016 0.95 9.4 0.1 2 23 897 919 896 919 0.95 15 23 4.7 2.9e+02 1.6 0.0 9 23 1161 1176 1144 1176 0.78 16 23 0.0013 0.08 12.8 0.1 2 23 1184 1205 1183 1205 0.97 17 23 0.032 2 8.4 0.7 1 23 1211 1231 1211 1231 0.89 18 23 0.0017 0.1 12.4 1.4 1 23 1236 1259 1236 1259 0.97 19 23 0.0049 0.3 11.0 0.9 2 23 1265 1286 1264 1286 0.96 20 23 0.0011 0.065 13.0 5.4 1 23 1290 1312 1290 1312 0.97 21 23 0.41 25 4.9 0.2 2 23 1323 1345 1322 1345 0.94 22 23 5.6e-05 0.0035 17.0 1.3 3 20 1353 1370 1352 1372 0.94 23 23 4.5e-05 0.0028 17.4 1.0 1 21 1381 1401 1381 1402 0.94
Sequence Information
- Coding Sequence
- ATGGAGGCAGTCAAAGTGAACGATAATTCCAGTGTTTGTACAAGAAAAGACTCTCCTCCACGGGATCAACTATGCGATGTTTGTCTTCGCAAAGAAAGCGTTTGTTTCAACAAAACCGACCCCATTTTCACCGGAAAGGATGTGTTGGCCATGATTACACAGCATCTGGATATAAAAATTTCAGTAATGGTCGTTTGTCAGCGTTGCTGGAACAGATTAGAGGATTTCGATGAGTTCTACCGAATGGTCAACGAACAACACAGCAAAAATGGTCTTCCCCCTGATCGAGAGAGAACCGGCACCGAACGAGTTTTTGGGATGGAATTTGTAGAGATAAAATGCGAACCCCTGGCAGAGGATATCACTGTGGCGGTGAAGGAGGAAAAGGAACTACTTACGGACAGTGACGAGTGCGACAAGCTGTCGCCCGAACAGCCTACCTTGGAGGACGATCATGAGGAACGTTTGCTTGATGATGATACGAATTCGTTTTCGTCGGACGATAGTGAAGATTCATCGGCGTCGGAACGAGTAAAAAGAGTTGGGAAAGCATCGCTCGACAAGAAAGAGCCCAAGGTAGATAAAGAGATACTAGAGTTCTACAAGCGATTGGTGTGCGAGTTGTGTGATGCGGAACGGATGCTGGCTGGTGAACCGTCGATCGAGTACGGCAATCTGAGGGAATTGAACAAGCACATGCGTAAGGTGCATGGGCAGGTGGGTGCTACAAGAATCAAGTGTCCGATGTGCGACAAAAAGTTTCGCTATCGCGCGAAGCTGCTCGAACATCGGGATGTGCATCTCAATCCGGAGCGGTTCCGGTGTGTTGTATGCGAGGAGGTGCATCAGAATATGGCAGAGCACATGAAGAACAAACATCAGGAACGAACGTACTGCTGTGATGAGTGTGGTAAACGATTTCCGTTCAAGGCCCGTCTTACGGCACATGTGAAGAAAATGCACACCTCGAAGGACGTGGTTTGCGACCAGTGTCAGAAAAGTTTCAGCAAATATACGATAGAGGATCATAGGCGAGCCGTTCATGAGTCGCGGTACATCTGTGAACACTGTCCGCGTACATTCAAGTCCCGCGTTTCCCTCACTCAGCACATGGAGGAACATGTGGAGGGGTTACGCAAGTCAGTGTCCGCCACCTGCGACAAGTGTGGCGTAGTGTTGCGGGACAAGTACACGCTTCAGACGCACATCAAGCGAATGCACACGGAACATCCACCCGCTAGCTGTGGTTCGTGCGGGAAGGTGTTTAAATCGAAGCACAATCTCAGCGTGCATCTGGCGAATGTGTGCACCGAGCGATCGTTCCCGTGTCCGATTTGTGGGAAGCAGTTTAAGAAAAAGATTAAACTAACCGAACACATGACAACTCACACCAAGAGTGTACTCTACAAGTGTCCGTACTGCCCGAAGACGTTCAGCTTCGAAACGCAGCTGTATACCCACCGGAAGCAGGCCCACTACGAGCAGTGGCTGGAGATGCAGCGGAAGCGCAAGGAGGGCGTACGGTTTAAGGTAACAATATGTCAAGTGTGCTTCTCTCGGGCGGAATGCGACTATAAGGACATTTTTGCCGAAGAAAACAAACATATTGTTGGAATCGTAGCGAAACATTTGGGATTTGAGATACCACCGACAACAGAAAATGCTTCTATGTGTAGCAAATGCTGGAGTGCGCTACACGATTTTGACAAATTTTACTGTGAAATAGAGGCAGTACGACGACAAGATCCTCAGGCAATTAGCGAGAAACAGGAGGAAGAAGCAGTTGTCGTTTGCGATAGCTCAGAACCAAGCTACAGTACGGAATTTTTCGAGGTAAAGATAGAACCATTCGAACCAGCGGACGCTTTCGAGAAGGAAAATTCCAACTGTTCCGACGAGCAACCGCTACATTGTGCGTTTGTAAAATGTGAAGAGCCCATCGAACTGGATCCAACAGCTCCGTCTTCCGATGAGGACTCCGGTCCGCATGACAACAGGTCCGACTCGTCGTCAATGACGGATAGCAGAAAGGCTAAGTATGAGAAGAAATCGAAAAGGCCTCAAACTAACGACAGCGAGACGACGAAGCTAAGCAAAGCGGCCGCACAGAAGGAGGAAGACGAAAGTTTGCTAAAGTTTTACAAACGGATCGTATGCGAAGTTTGCGATATTCAGCGCATGCTGGTGGGTGAACCTCAGATCGACTTTGGCACGTGGCGAGCACTGTTACGGCACACGAAGGAGGTACACAAGCACGACAAGGTGTACGTAAAGTGTCCGGTGTGCGAGATGAAAATGCGTACGAAACAAACGCTGCTGCAGCATATGGATTGGCACGAAAATCCGGAAAAGTATCGGTGCGAGCTGTGTGGTGAAAAGCATCAGAACATGAAGGAACACATTCAGAACAAGCATCAGGAGCGTCAATTCTGTTGCGATGTTTGCGGGAAAAAGTTCCCCTTTAAGAAGAGACTTACCGTGCACATGAAGAAGATGCACGTTGAAAAAGACATCATTTGTGACCAGTGTCAGAAACCCTTTACAAAGTATACAATCGAAGATCACAAGCGGTCCGTACATTCGGCGCGTTTTGTCTGTGAGCACTGTCCGAAGACGTTCAACAGTCGCTTCCGGTTGTTGCAGCACATGGAGGAGCACGACGAAAGCCTTCGAAATTCTACCTCCGTACCGTGTACTATTTGTGGACAGGTGATGCGCGACAAGTATATCCTTACCAGACACATTAAGTTGATGCACACGGTGCAACCGTCGTGTACGACGTGTTTCTCCGTTAGCGAGCCAGAATATTTGAACATTTTTGCCGAGGAAAATGTATCGAAGAACATTGCCACAATTGTTGCCATTCATCTTTGGTTTGAGGTAGTTACTCCCACGGATGCATGCCAGTGGATATGCCGGGCCTGTTGGACAAGCTTGGATTCGTTTCACACTTTCTATGTCAGCATTGAGGAAAAGCATGAACGACAAAATGGGACTGTTGTCGAGAGTATCCTCGACAATGAAAAGGCGGCTAGATCGTCCAatagcccgcccgatagcccgcccgctagcACTTGTACTGGTCCCACATACAACACGGAGTTTCTCGAGATAAAGGGTGAGCCGCTGGACGACGATGAGATGGACGACCAAGATGAGGAAGGGTTTGACTTAACGGATGGTAGCGGAAGTGACAAAATGTTACCGAGTGAAGAGATCAAGAGTGAAACTGATTCAGAGGGAGCCGAAAGCGTATCATCCCAGGCGGAGGAAGAGAACAGGAAAAGGCAACGTTCTGTCAGGTCTCGCAATGCTTCTCGTGTTCCGCAGAGAGATACTGGTGAGCAGCTTGCGAAACGAAAGGCTGGTGGTCGGTTTCCCGCTGATCCGGAGGAGGATAAGAATTTACTGCAATTCTATAAGCGTATCGTGTGTGAAGTTTGCGACAACAAGCGGATGATGGTGGGTGAGCCGCTGATAGAATACGCAACGTGGGGTGAACTGTTGCGACACACGAAAGAACTGCACGGACATTACAAAATCTTCGTCCAGTGTCCGGTGTGTGAGATGAAGCTGCGCACAAAGGTGACGCTGGTGCAGCACATGGATATGCACCAGAACCCGGACAAGTATCGATGCGAAGTGTGTGGCGAGGTATTCCAGAACATGAAGGAGCACATGCAGAACAAGCACGAAGAGCGACAGTTTAGCTGCGATCAGTGTGGCAGCAAGTTTCCGTTCAAGAAGCGGCTCGTAGTACACATGAAAAAGATGCATGCGGAAAAGGATGTCACGTGTGATCAGTGCCAGAAATCCTTCACAAAGTACACCATCGAAGACCATCGGCGTTCGGTGCATATGGACCGGTTTGTGTGTGAGCACTGTCCGAAAACGTTCAAAATTCGGTTCCGACTGCATAAGCACATGCAGGAGCACGATAAAAGCTTGCGCATCTCCACTTCCGTGCCCTGTCCGACCTGCGGGCAGGTGATGGGCGACAAGTACATTCTTCGGCAGCACATCAAGCATATGCACGTCGAGCAGCAGGCGGTGGATTGTGAGACGTGCGGGAAGACGTTCAAAAACCATCGGAACCTAAAGATACACCTGACGAACGTGTGCATGAAACCCGTTCAGCTGCATCCGTGTGCAATCTGTGGCAAGCAGTTTCGGCATAAAAACAAGTTGAAAGATCATATGGCCTCTTGTACGCCGAATTGA
- Protein Sequence
- MEAVKVNDNSSVCTRKDSPPRDQLCDVCLRKESVCFNKTDPIFTGKDVLAMITQHLDIKISVMVVCQRCWNRLEDFDEFYRMVNEQHSKNGLPPDRERTGTERVFGMEFVEIKCEPLAEDITVAVKEEKELLTDSDECDKLSPEQPTLEDDHEERLLDDDTNSFSSDDSEDSSASERVKRVGKASLDKKEPKVDKEILEFYKRLVCELCDAERMLAGEPSIEYGNLRELNKHMRKVHGQVGATRIKCPMCDKKFRYRAKLLEHRDVHLNPERFRCVVCEEVHQNMAEHMKNKHQERTYCCDECGKRFPFKARLTAHVKKMHTSKDVVCDQCQKSFSKYTIEDHRRAVHESRYICEHCPRTFKSRVSLTQHMEEHVEGLRKSVSATCDKCGVVLRDKYTLQTHIKRMHTEHPPASCGSCGKVFKSKHNLSVHLANVCTERSFPCPICGKQFKKKIKLTEHMTTHTKSVLYKCPYCPKTFSFETQLYTHRKQAHYEQWLEMQRKRKEGVRFKVTICQVCFSRAECDYKDIFAEENKHIVGIVAKHLGFEIPPTTENASMCSKCWSALHDFDKFYCEIEAVRRQDPQAISEKQEEEAVVVCDSSEPSYSTEFFEVKIEPFEPADAFEKENSNCSDEQPLHCAFVKCEEPIELDPTAPSSDEDSGPHDNRSDSSSMTDSRKAKYEKKSKRPQTNDSETTKLSKAAAQKEEDESLLKFYKRIVCEVCDIQRMLVGEPQIDFGTWRALLRHTKEVHKHDKVYVKCPVCEMKMRTKQTLLQHMDWHENPEKYRCELCGEKHQNMKEHIQNKHQERQFCCDVCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHTVQPSCTTCFSVSEPEYLNIFAEENVSKNIATIVAIHLWFEVVTPTDACQWICRACWTSLDSFHTFYVSIEEKHERQNGTVVESILDNEKAARSSNSPPDSPPASTCTGPTYNTEFLEIKGEPLDDDEMDDQDEEGFDLTDGSGSDKMLPSEEIKSETDSEGAESVSSQAEEENRKRQRSVRSRNASRVPQRDTGEQLAKRKAGGRFPADPEEDKNLLQFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKELHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPDKYRCEVCGEVFQNMKEHMQNKHEERQFSCDQCGSKFPFKKRLVVHMKKMHAEKDVTCDQCQKSFTKYTIEDHRRSVHMDRFVCEHCPKTFKIRFRLHKHMQEHDKSLRISTSVPCPTCGQVMGDKYILRQHIKHMHVEQQAVDCETCGKTFKNHRNLKIHLTNVCMKPVQLHPCAICGKQFRHKNKLKDHMASCTPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -