Basic Information

Insect: Anopheles bellator
Gene Symbol: Thap3
Assembly: GCA_943735745.2
Location: OX030928.2:71074015-71076418[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.9 1.1e+02 3.3 0.0 2 13 151 162 150 164 0.87

2 9 1.7 96 3.5 0.4 3 14 464 475 463 482 0.82

3 9 0.092 5.3 7.4 2.4 3 21 500 518 498 519 0.90

4 9 9.6e-07 5.5e-05 23.1 0.5 1 23 575 597 575 597 0.98

5 9 0.018 1 9.6 0.9 1 21 605 625 605 626 0.94

6 9 0.00072 0.042 14.0 2.7 1 23 667 689 667 689 0.97

7 9 5.5e-06 0.00032 20.7 0.7 1 23 695 717 695 717 0.98

8 9 4.4e-06 0.00025 21.0 1.0 1 23 723 746 723 746 0.97

9 9 0.83 48 4.4 0.1 1 14 752 765 752 769 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.9	1.1e+02	3.3	0.0	2	13	151	162	150	164	0.87
2	9	1.7	96	3.5	0.4	3	14	464	475	463	482	0.82
3	9	0.092	5.3	7.4	2.4	3	21	500	518	498	519	0.90
4	9	9.6e-07	5.5e-05	23.1	0.5	1	23	575	597	575	597	0.98
5	9	0.018	1	9.6	0.9	1	21	605	625	605	626	0.94
6	9	0.00072	0.042	14.0	2.7	1	23	667	689	667	689	0.97
7	9	5.5e-06	0.00032	20.7	0.7	1	23	695	717	695	717	0.98
8	9	4.4e-06	0.00025	21.0	1.0	1	23	723	746	723	746	0.97
9	9	0.83	48	4.4	0.1	1	14	752	765	752	769	0.81

Sequence Information

Coding Sequence: ATGCCTGCCTCGTGCGTAATACTGGATTGCAATCTAaaatacacacatacacaggagGTGTCGTTTCACAAGTTTCCGTTCAAAAATCCCGAGCTGCTGAAGCAGTGGATCGCATTTACCGGGCGCGACGCAAGCTGGTACCCGACTCAATGGAGCACCATTTGCAGTCGGCACTTTCAGGCCACCGATTTCAGGGAGTGTCCGTACCGGAAAATGCTCTGCATCAATGCGGTTCCACTGATACGGGACGGCAGTGGGTTAAGGGAAACCGATATCGGCACCTCCGTGTACGAGATAAGCACCACGGAAGAGATACTACAGCGGCACGATGGCTGCTATCAGCCGGAGGAGCTGGATTTCTCCGGACAGAACGAGTTTCAGTGCCCACCCGGGATCCGGTTAATAGAGGCAATCGACGAAGAGCTGCAAGAAGATGACTTAGCGGAGATCACTTGCCGAGTGTGTGGCGTAGTGTATAGCCGTGCGGCCGACAAGCTGCTGTCCGATCTAAGCCAATCCGCCGGCGTTATAGGCAAATATCTACCCTTCGTGAATCTGGATCTACCGAACCTTCCGCGGAAGATTTGTGGTGAATGCTTGAAGATGGTGAATGGATTTTCGACATTTTGCGACAACATATTGCGAGCACAAACGGACCTGGAGCATCGCTTTCTATACGATGGGTCCGTCGTTGCCGAGCCATCTCCGGCCTCTGCTTCGATCCGAAGCGCTCCGGATGCCGCCAGTAAAccgatgaaaataaaacaggaACCCATCAATTTCATCAAGGAGGAGAAGATCGAGGGTGCCAATAGTGGACACCTGCGGAAGGAGAAGGAATtagcggcaccggaagcaaaccCGACCGCAAGCGGCATGTTTTTCAAACCGTTCCAAACCTTTGCCAACGACAAAAATCGCATCATTCTCTTCGGTAACGCCAGCGGTAAGGATCGGTCGAGCGATACGCAGCGGGATTCGTCGAAAAACTGCGAAATCCTCGAGATAGTGAACCTCTACCCACCGATCGTGGACATTACCAGTGCCACGATCACGGAGATGCAACCGTACGAGAACTCGCTGCAgccgccactgctgccggCCACTGCGACCGGAGCACCGATGATGGGTGGCAGACTGAAGGTGGAGAACACGGCCGATGTTGAGGCGGACCTGGATGAGTACTATCAGCCCGATCTGCCCGATACGCTGCACCTGATCAATACACTCGAGGAACACAGTTATACGAAACTTCCGATTCAGGCGGACGATAAGGATGAAATTTTTAACGATCTTAAAACCGGCAACCCGCATCAAGCGGACGGTACTCGGGTCACTCGGGAGGTGAAGTGCATCGAAGACAACGAACCTTCCGGTGTCGGTTGGTTATGCGGTGACTGCGGCCAAGCGTTTCGCATGCACCGTGAAATGCTGTGCCACCGAATGCTGACGTGTCCCGTGCGTCGAAAGGTCGGTGGATCGGTGGCTGCCCAGTGCTGTCGGTGGTGCAAGCGAAAGTTTGCCTCGGCACACAGGCTTCGAGTGCACAGGATGGCAGCACTGTGTCCGAAGCGACCACAGAGACGGAAACTGTTCGACCTGAAAGCGATCCTCGCACGGGACAAAGCTCCACCGGCGCCAGCAGTGATCCCACCGGCCATCGCCAGTACCGACAACGCTTCCGTACCTCTCGGTGGCGACGGTCCGGTAGAGGACACACGCTACCCTTGCTCGATGTGTGATAGAACGTACGTATCGCTGTCGAACATGCGCCGCCACATGGCCACGCATCGGCCCATGGCCCAGTGGAACCACAAGTGTGGTATTTGCTTGAAAATCTTCGACAAACTGCTCGATCTCAAGAAACACCTGCACATCTCGTTGTGTGGTAATCAAACCATCAATCCGCGCGAGGATTCGCCCACCGACCCGGCGGTTGGCGACTCGGCAACGGTGGGAAACGTAGAGTCGTCGCAGGCGCAGATCGATCGGCTGCTGTACGTGTGCTCCACCTGCAACAAGCACTACCGATCGTACAACAGCCTCAGGGTGCACGAGTCCGTGCACACCGGCATCAAGGCGTACATCTGCGAGAAGTGCGGCAGGCGGTTCAGTGGCCAAATGAATCTCTTGCAGCACCGGCTAACGCACTCCGAGATCCGCCAGTACCACTGCGAGCTGTGCCCGAAGGTGTTCAAGCGGAAAGGTGGTCTCAGCCAGCACGTGCGGAGCGTCCACCTGCAAATTCGCCCTTTCCAGTGCGAAACGTGTGGTCACCATTATGCGCTCAAAGCCGACATGGCACGGTGTCGACATTCCAAGCTGAAAGATGCCGTCAACTATTAG
Protein Sequence: MPASCVILDCNLKYTHTQEVSFHKFPFKNPELLKQWIAFTGRDASWYPTQWSTICSRHFQATDFRECPYRKMLCINAVPLIRDGSGLRETDIGTSVYEISTTEEILQRHDGCYQPEELDFSGQNEFQCPPGIRLIEAIDEELQEDDLAEITCRVCGVVYSRAADKLLSDLSQSAGVIGKYLPFVNLDLPNLPRKICGECLKMVNGFSTFCDNILRAQTDLEHRFLYDGSVVAEPSPASASIRSAPDAASKPMKIKQEPINFIKEEKIEGANSGHLRKEKELAAPEANPTASGMFFKPFQTFANDKNRIILFGNASGKDRSSDTQRDSSKNCEILEIVNLYPPIVDITSATITEMQPYENSLQPPLLPATATGAPMMGGRLKVENTADVEADLDEYYQPDLPDTLHLINTLEEHSYTKLPIQADDKDEIFNDLKTGNPHQADGTRVTREVKCIEDNEPSGVGWLCGDCGQAFRMHREMLCHRMLTCPVRRKVGGSVAAQCCRWCKRKFASAHRLRVHRMAALCPKRPQRRKLFDLKAILARDKAPPAPAVIPPAIASTDNASVPLGGDGPVEDTRYPCSMCDRTYVSLSNMRRHMATHRPMAQWNHKCGICLKIFDKLLDLKKHLHISLCGNQTINPREDSPTDPAVGDSATVGNVESSQAQIDRLLYVCSTCNKHYRSYNSLRVHESVHTGIKAYICEKCGRRFSGQMNLLQHRLTHSEIRQYHCELCPKVFKRKGGLSQHVRSVHLQIRPFQCETCGHHYALKADMARCRHSKLKDAVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097116;
90% Identity: iTF_00094525;
80% Identity: iTF_00094525;