Basic Information

Insect: Anopheles bellator
Gene Symbol: zfh1
Assembly: GCA_943735745.2
Location: OX030929.1:1334756-1350104[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.45 26 5.2 1.2 2 23 54 76 53 77 0.94

2 9 0.0021 0.12 12.5 0.2 1 23 294 316 294 316 0.94

3 9 0.00013 0.0075 16.4 1.3 3 23 324 344 322 344 0.96

4 9 3.5e-06 0.0002 21.3 5.8 1 23 353 375 353 375 0.99

5 9 6.5e-05 0.0037 17.3 1.3 1 21 381 401 381 402 0.95

6 9 0.00047 0.027 14.6 0.5 2 21 860 879 859 880 0.93

7 9 2.4e-05 0.0014 18.7 4.0 1 23 1316 1338 1316 1338 0.95

8 9 7.4e-05 0.0043 17.1 7.2 1 23 1344 1366 1344 1366 0.98

9 9 0.066 3.8 7.9 7.0 1 21 1372 1392 1372 1393 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.45	26	5.2	1.2	2	23	54	76	53	77	0.94
2	9	0.0021	0.12	12.5	0.2	1	23	294	316	294	316	0.94
3	9	0.00013	0.0075	16.4	1.3	3	23	324	344	322	344	0.96
4	9	3.5e-06	0.0002	21.3	5.8	1	23	353	375	353	375	0.99
5	9	6.5e-05	0.0037	17.3	1.3	1	21	381	401	381	402	0.95
6	9	0.00047	0.027	14.6	0.5	2	21	860	879	859	880	0.93
7	9	2.4e-05	0.0014	18.7	4.0	1	23	1316	1338	1316	1338	0.95
8	9	7.4e-05	0.0043	17.1	7.2	1	23	1344	1366	1344	1366	0.98
9	9	0.066	3.8	7.9	7.0	1	21	1372	1392	1372	1393	0.96

Sequence Information

Coding Sequence: ATGGTGTCCTGTAGCGTGGCGGTGCCGACGTACTACaaagcagcagaagaaagtaTCATGCCATCGTCGACCAAGTTTTCATTGCAATTTCCTTCCCTGACGTCTGGGCTGCCCAAGGATAGTGAAACCAATACACTAGCCGCCGCCGACTGCTGCGTCCAGTGCCCCCAATGCCACCAGACCGTTCAAGGAATCGAGATGCTCAAAGACCAcatacagcagcagcaccacagtACTGGTAGCGACGTggacgacgacagcagcagtaACCACCTGGCAGTGCCACGAGCAGAGCCTCACAACGGTGCCAGCTCGGGTGACGCTGGTAGCAGTGATCCGGATGCTGAGAACGATGACGAGGAGGGCGCCGAGGAGGATGCCGAAgtcgacgaagacgacgacgtggaCGCAGCCTCCGAAATAGTCCGGGTCCCATTCGCGCCGCTCGAGCTGCTGGTGGGGGGCAAGAGCAGCCGGGCGAGTGGAGATCTCGTCGGCAGTCGGTTACAGGCGAAGTGCATCAgtttgctgcagcagcagcaggagcagcagcttcgCCAGGCCAAAGAGcagcccaccaccggccggaaccggagcctgGCCAAGGAGGACGAGACCGACCGGGATGACGAGCAGACAGAGGTAGGAGGGTCGGAAACGACGACACTGACGCCCACGCCGATCGGCGTCGGTGGCAGTGCGGACCTCCAGCACCCTCCGTACCATCTGTCGCCGCCCTATCACCTCCAGCAGACCAATGGATCGTACGGCCGCAGCACGCCGGTGATCAGTCCGGCGCGGAGCGGCAGCAGTAACGCCAgcagcgccgccagcagcaccgccagctGCCTGCTGTCCGGTAAGGACCCCGAGATGATGTACCTCTGTGCGCAGTGTCCAGCGACGTTCGCGAGTCGCAGTCAGTACGAGAAGCACGAGATGCAGCACTCCGCCTCGGCCGTCGTGTGCTGCAAGGTGTGCAACAAACCGTTCGCCAACGTGTACCGGCTGCAGCGGCACATGATTTCGCACGACGAGTCGACCCTGCTGCGGAAGTTCAAATGCAACGACTGTGATAAAGCGTTCAAGTTTAAGCATCACCTGAAGGAGCACGTGCGTATCCACTCGGGCGAGAAACCGTTCGTCTGCAGCAACTGCGGCAAGCGCTTCTCGCACTCCGGCTCCTACTCGAGCCACATGACCTCGAAGAAGTGCATCAACATCGGCATCaagatgcaccaccaccaccaccaccaccagctccagcacaactacaacaacaacactagtagcaataacaaaaacaacacacactaCCCGCACAAGaacagtagcagtagcagcagcagtagcaacaacaacaacaatagtgGCCTTGCGATAAACGTCAACTGTGTGGCGAGTGGTGGGAGAAAGTCACAGGCGCTGTCACAGGCGCCGGTCGCTGTCATCGATCACCGTACGGCCGCCGGCAGGGCGGCCgtcgcggccgccgccgccgccgccgccgccctccACCTCGACCTGGACTGGGCGACGGGCGGGGGGATGCGGGCGCTCGGAGGGAAACCGGGCCACCTTCCCATCTCgccctcctcctcctccgcgTCCTCGTCTTCCTCGGCCCCGGTCGGCCCGCAGACCCTTGaaggatcgtcgtcgtcgtcgtcgtcggcggcggcggcggccgtagctgccgtggccgccggtgccgccggtctgccggcggcggcggcggccgacgcCCTGTTTCCGATGCTCTCCAAGTACACGCAGTCGAACTACGGTGCGATGAACCTGCTGGCCACACTCGGCAACCCGTTCTACTCGATGGCGATGATCAGCAACCAGACCTACAGCCTGCAGTGTTTGCTTGAGCTGTCGGCGgctgcccagcagcagcagcagcaccaccaccaccagcaaaccGCGGCCGACACGATGGGTTCGCTGATCTACAAACCCCACGGACAGCTGACAGGCAGCGAAGAGgcagaggaggaagaggaggcACAGGAGCCGGGCGCCGCCCGGGAGCCGGCGGCCAGTGACGCGTGTGCGGTGGCCCTACCGTCCCCCGGCAAGGGCCACGAGGACGAGCTGATCGTGGACAGCCCCGAGGAGGCCCCCATGGAGGTTGACGGGGACGGCGAGAAGGTGGAACCGCTCGCGGAATGTGATATGGCCGGTGAAGATGCGGCCGAGGACGATAGCTCTGctgcgggcggcggcggccgggaaCAGGATTCGGGTGCCACCATCAAACCGGACGATCCGGACGGGGAGGTCGAAAGGGACGGGAGTTGGCGGTTCGATCCGCTTCCGACCAAACAGGAACCACCGGACGCTGCCGATGTGCCGATGGATGATACGGGGCCAGGACACCCCACCGAGCGGCATCCGTACGGGGGTGGGCAAggatcaccggaaccgggagcaccggtggcgatgaaaacggaaccacTGGAACCGGCGGAGCGGGTGTATGAAAaatcgccgccaccaccaccaccaccgctgccgcactcttcgtcctcgtccgggttgccggcggccgtcgccgttgccgcGCAGCTACAGTGCGTGTACTGTGGTCACAACTTTTCCAACCAAACCGAGCTGATGCAACACACGCAGCTGTTCTGCAAGGAGTCGCTCCTGCGGAATCAGttcgtggcggcggctgcggtaGCGGCGAGTGCCGCCGCCATGCCGTTGACGGCGGCGTTGGGTGCGGACAGCACCACGACGTACGGGAGCAGCTGCAGTGAAGATGACACCGACTACGAGACGACGGCGCTGGTGATGAATCAAGCGGCCGGCGCCAGCCAcccgaccggtggccaggGGCACgtgacgagcagcagcagcagcggaagtggctgcagcagcaccggcagcagcaaggtTCGCGTCCGGACGGCCATCTCGGAGGAGCAGCAGAGCGAGCTGAAGCGGTACTACGCGCACAACAGCAAGCCGAGCCGGGACGAGTTTCAGGCCATCGCCCAGCACGTCAAGATGGAGGCCCGGGTGGTGCAGGTCTGGTTCCAGAACAATCGGTCCCGCGAGCGCAAGATAGGCTCGGCGCTGGGCCCGACCGGcgacccggtggtggccggagcGGCCCCCAGTTCGCCCCTGCACGCCGACCGTGCCCCGTCGGTGGTGACGGGGCACGAGGCCACCGATCAGCCGCTCGACCTGTCGCTCAAGAAGGACCTCGCGATGGCGGAAGGAGCGGCCCTCCTGAGTGCGGCGGCCAGTGACTCGACGGCCACCTCAGGGGCGGTGGGGTCCCTGCCGGCCGTCCTGCTGCAGGCTGCGGGCCAGGCCGACACCATGTCGGCGCTGAACGAAGCGATGAACCTCACGATCAAAACATCCCACTTGCCGGCCGCGTTCTACTACAACGACATTCACCCGATCCACCACAATGCCAACGCGCCGGCTCCGCTGCAGCTGAGCTTCGACGACAGCCTACGCAAAgcgtcgtccccgtcgtcgcACCACCAGCCCCTGCTGTACACGCACCTGGCGGGGCAACCGGGCACATTCCGGGGGCCGTCGATAGCGGCCCTCCACCATCCGGCCGGCCTGCCCGGTCCGCTGGATCCGATGTTCCACCAGATCTCGCCGAAACTAGCTAGCACCGGTGCTAGCGCCGGGAGCGGTACCAGCCTCGCTAGCCTTAGCCCGGTACCGCGGGACGACCTGCACGACGcggtgggcggcggtggcggtgggtaCGAGGTAACCGGCAGCAAGTACTACGGTGCGTTCAGCGAGAAGAAGATGCTCCAGTCGATGCTAAACGTGCCGAAGCGTGTGGCCCCACCCTACGTTTGCAGCACCAtcatggcggtggcgggccAGGGGAGTGCTAAGGACaatcagcatcaccagcaccagcaccagcaccaggcaccggACGCCGAGGGGCAGTACGTTTGCGATCAGTGCGATAAAACGTTCAGCAAGCACAGCTCACTGCAGCGGCACAAGTACGAGCACTCGGGTCAACGGCCGTACAAGTGCGTCGAGTGCCCGAAAGCGTTCAAGCACAAGCACCACCTGACCGAGCACAAGCGGCTGCACAGTGGCGAGAAGCCGTTCCAGTGCTGCAAGTGCCTGAAGCGCTTCTCGCACTCCGGCTCCTACAGCCAGCACATGAACCACCGCTACTCGTACTGCAAGCCGTACAGGGATGGCAAATAA
Protein Sequence: MVSCSVAVPTYYKAAEESIMPSSTKFSLQFPSLTSGLPKDSETNTLAAADCCVQCPQCHQTVQGIEMLKDHIQQQHHSTGSDVDDDSSSNHLAVPRAEPHNGASSGDAGSSDPDAENDDEEGAEEDAEVDEDDDVDAASEIVRVPFAPLELLVGGKSSRASGDLVGSRLQAKCISLLQQQQEQQLRQAKEQPTTGRNRSLAKEDETDRDDEQTEVGGSETTTLTPTPIGVGGSADLQHPPYHLSPPYHLQQTNGSYGRSTPVISPARSGSSNASSAASSTASCLLSGKDPEMMYLCAQCPATFASRSQYEKHEMQHSASAVVCCKVCNKPFANVYRLQRHMISHDESTLLRKFKCNDCDKAFKFKHHLKEHVRIHSGEKPFVCSNCGKRFSHSGSYSSHMTSKKCINIGIKMHHHHHHHQLQHNYNNNTSSNNKNNTHYPHKNSSSSSSSSNNNNNSGLAINVNCVASGGRKSQALSQAPVAVIDHRTAAGRAAVAAAAAAAAALHLDLDWATGGGMRALGGKPGHLPISPSSSSASSSSSAPVGPQTLEGSSSSSSSAAAAAVAAVAAGAAGLPAAAAADALFPMLSKYTQSNYGAMNLLATLGNPFYSMAMISNQTYSLQCLLELSAAAQQQQQHHHHQQTAADTMGSLIYKPHGQLTGSEEAEEEEEAQEPGAAREPAASDACAVALPSPGKGHEDELIVDSPEEAPMEVDGDGEKVEPLAECDMAGEDAAEDDSSAAGGGGREQDSGATIKPDDPDGEVERDGSWRFDPLPTKQEPPDAADVPMDDTGPGHPTERHPYGGGQGSPEPGAPVAMKTEPLEPAERVYEKSPPPPPPPLPHSSSSSGLPAAVAVAAQLQCVYCGHNFSNQTELMQHTQLFCKESLLRNQFVAAAAVAASAAAMPLTAALGADSTTTYGSSCSEDDTDYETTALVMNQAAGASHPTGGQGHVTSSSSSGSGCSSTGSSKVRVRTAISEEQQSELKRYYAHNSKPSRDEFQAIAQHVKMEARVVQVWFQNNRSRERKIGSALGPTGDPVVAGAAPSSPLHADRAPSVVTGHEATDQPLDLSLKKDLAMAEGAALLSAAASDSTATSGAVGSLPAVLLQAAGQADTMSALNEAMNLTIKTSHLPAAFYYNDIHPIHHNANAPAPLQLSFDDSLRKASSPSSHHQPLLYTHLAGQPGTFRGPSIAALHHPAGLPGPLDPMFHQISPKLASTGASAGSGTSLASLSPVPRDDLHDAVGGGGGGYEVTGSKYYGAFSEKKMLQSMLNVPKRVAPPYVCSTIMAVAGQGSAKDNQHHQHQHQHQAPDAEGQYVCDQCDKTFSKHSSLQRHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYRDGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094381;
90% Identity: iTF_00094381;
80% Identity: iTF_00094381;