Basic Information

Insect: Anopheles bellator
Gene Symbol: grau
Assembly: GCA_943735745.2
Location: OX030927.2:46869533-46871657[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.18 10 6.5 0.3 2 23 225 249 224 249 0.92

2 12 3.2e-05 0.0018 18.3 1.5 3 23 258 278 258 278 0.99

3 12 4.7 2.7e+02 2.0 2.5 6 23 322 340 310 340 0.87

4 12 0.0065 0.37 11.0 0.6 2 23 348 369 347 369 0.97

5 12 0.24 14 6.1 1.7 10 23 438 452 437 452 0.92

6 12 0.0016 0.093 12.9 1.2 2 23 460 481 459 481 0.96

7 12 1.4e-05 0.00082 19.4 1.8 1 23 512 535 512 535 0.95

8 12 0.0016 0.094 12.9 0.5 3 23 542 562 540 562 0.96

9 12 1.8e-06 0.0001 22.2 0.6 1 23 568 590 568 590 0.97

10 12 0.00051 0.029 14.5 0.6 2 23 602 624 601 624 0.96

11 12 8.9e-06 0.00051 20.0 2.3 2 20 631 649 630 651 0.94

12 12 2e-06 0.00011 22.1 1.8 1 23 658 681 658 681 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.18	10	6.5	0.3	2	23	225	249	224	249	0.92
2	12	3.2e-05	0.0018	18.3	1.5	3	23	258	278	258	278	0.99
3	12	4.7	2.7e+02	2.0	2.5	6	23	322	340	310	340	0.87
4	12	0.0065	0.37	11.0	0.6	2	23	348	369	347	369	0.97
5	12	0.24	14	6.1	1.7	10	23	438	452	437	452	0.92
6	12	0.0016	0.093	12.9	1.2	2	23	460	481	459	481	0.96
7	12	1.4e-05	0.00082	19.4	1.8	1	23	512	535	512	535	0.95
8	12	0.0016	0.094	12.9	0.5	3	23	542	562	540	562	0.96
9	12	1.8e-06	0.0001	22.2	0.6	1	23	568	590	568	590	0.97
10	12	0.00051	0.029	14.5	0.6	2	23	602	624	601	624	0.96
11	12	8.9e-06	0.00051	20.0	2.3	2	20	631	649	630	651	0.94
12	12	2e-06	0.00011	22.1	1.8	1	23	658	681	658	681	0.97

Sequence Information

Coding Sequence: ATGGTCGAACGGGGCGATGTTTACGATGTCACCATCAATCAAAAAGAGTGCGGAGTGTGTCTTACGCTCCGCCCGGACCATATCTGTCTGGATGTGTTCGAACCGCAGGGCGACGAGTCGGATAAGGAGGTGCCGTATCTTGTGTGGAAGCATGTGGGGCTACAGTTTACGCAGGGCGCCGAGCCGCAGTTCATCTGTTGCGATTGCTGGAAGGCGCTGCAAGAGTTTAACCGCTTCTACATGATGGTTCAGGATGTGCACACGCAGCGAACTTCGTACCTTGCGGCGAACCGCGCGAAGCCGGACGGTCCAAACCAAACTGCTGACACGGTGCCCATCGCGAACGGTGTGCATGCCAGTGAGTGCGAGGCGATTGCCGCACCAGCGCCACTAGCTTACGGAGAGCAGTTGTTGGACCCGGCCACGACGGATGTTGTGCACAACAATGGTATCCCGGTAGCCACTGCGGCACCCGAGTGTCCACCCCGTGGCGGGCTGGTTGAACACGCGGAATCGGAAAGGATACCGTGCGCAGCTGATACCGATCGTTCCGGTTTGGAACCGGAAGGTAGCCACGTAACGCCAACGGCCAACACCATCGTCGGCACACCGAGTCGGAAGAGGAAAAATCAAGAGATGGACGAAGAAATACTCGATTTTTACAAGCGTCTCGTGTGCGATGTTTGTGACGATCGCACCGAGTACGGTACGCTGAAGGAGTTGAACCATCATATGAAGCTTGCGCACGGTGAAGAGTCAGGACGCGTTGGTTGTCCACAGTGTGGTAAAAAGTTCCGCACGCGAGTAAAGCTGCTCGAACATAAGCAAACTCACGTGCCACGGATGCTGAGCGACGGGGAAACGGACGCCGACAAGGTACAGTCGGCGCAGGTTGACCAGGAAATACTGGAGTTTTACAAGCGAATTAGTTGCGACGTGTGCGACGGCGCGACGCCGACACCATGCTCCACCCTGTACCCCACGGTACGGGAATTGAACCACCACATGAGGCTAGTGCACGGCCAGCAGACGGGAACGGTCAAGTGTCCGCTGTGTGAGAAGAAGATTAGGACGCGTCCGAAGCTGCTCGAACACAAGCGGCTGCACCTGCCGGAGGCGGCGACAGCGGTAGCGGCACCACCAgggccgatggtggtggtggtggacgatGATCACGGCAGGTCACCCGACGTGAGCCCGGAGCAAATGGAAGAGCAAACGTTCGATGTGGAAATTTTTGAATTCTACAAACCCATCACCTGCGAAATGTGCGATCCGGATAAGCTGGTGAACGGTGAACCGGTGGATGAGTATCGCACGCTACGGCAGCTCAATCACCACATGCGCACGGCACACGGGCTCGATTCGGGGACGATCAAGTGTAAGCTGTGTGCGAAAAAGTTCCGCACGCGCGTGAAGCTGGTGGAGCACAAGGAGATGCACCAGAATCcggatcgatttcggtgcACCGTCTGCCAGGAGGTGCATCAGAATTTGGAGGAACACATGCAGAACAAGCACCAGGATTGGGAGTTTTGCTGCGAAGAGTGCGGCAAGCGGTTCCCGTTCAAAAGTCGGCTAACCGCGCACATGGGCAAGGTCCACCAGAAGAAGGACATTATTTGCGAGGAGTGCAACAAGCCGTTCACCAAATTCAGCATTGAAAAGCACAAGCGGACTGTGCACGGTTCGTACACAACGTTCACGTGCGAAAACTGTcccaaaacattcaaaacgcGTGTCTCACTCGATCGGCACATGGAGGCACACAACGGTGGTGAGCAGCAGGGTTCGGCCACCGTCAGCTGCACCCTGTGCAATTCGGTGCTAAAGGATGAGTATAACCTGAAGACGCACATGAAGCGAATTCACGCCGAACAGACGCCCTCCACGTGCAAAACGTGCGGCAAAACCTTTAAATCCAAACATAGTCTTAATACGCACATTTCGAACGTCTGCACGACGCGCCAGTTCCCGTGCACGGTCTGTGGCAAGCAGTTCAAGAAGCGAACAAAACTAAAGCAGCACATGACGACGGCTCACGCCCGTTGCGCAGACTAG
Protein Sequence: MVERGDVYDVTINQKECGVCLTLRPDHICLDVFEPQGDESDKEVPYLVWKHVGLQFTQGAEPQFICCDCWKALQEFNRFYMMVQDVHTQRTSYLAANRAKPDGPNQTADTVPIANGVHASECEAIAAPAPLAYGEQLLDPATTDVVHNNGIPVATAAPECPPRGGLVEHAESERIPCAADTDRSGLEPEGSHVTPTANTIVGTPSRKRKNQEMDEEILDFYKRLVCDVCDDRTEYGTLKELNHHMKLAHGEESGRVGCPQCGKKFRTRVKLLEHKQTHVPRMLSDGETDADKVQSAQVDQEILEFYKRISCDVCDGATPTPCSTLYPTVRELNHHMRLVHGQQTGTVKCPLCEKKIRTRPKLLEHKRLHLPEAATAVAAPPGPMVVVVDDDHGRSPDVSPEQMEEQTFDVEIFEFYKPITCEMCDPDKLVNGEPVDEYRTLRQLNHHMRTAHGLDSGTIKCKLCAKKFRTRVKLVEHKEMHQNPDRFRCTVCQEVHQNLEEHMQNKHQDWEFCCEECGKRFPFKSRLTAHMGKVHQKKDIICEECNKPFTKFSIEKHKRTVHGSYTTFTCENCPKTFKTRVSLDRHMEAHNGGEQQGSATVSCTLCNSVLKDEYNLKTHMKRIHAEQTPSTCKTCGKTFKSKHSLNTHISNVCTTRQFPCTVCGKQFKKRTKLKQHMTTAHARCAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097279;
90% Identity: iTF_00097279;
80% Identity: -