Basic Information

Insect: Anopheles bellator
Gene Symbol: L_1
Assembly: GCA_943735745.2
Location: OX030927.2:1756482-1771584[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00013 0.0073 16.4 3.6 1 23 169 191 169 191 0.97

2 17 0.65 38 4.7 5.7 1 23 197 219 197 219 0.98

3 17 5.4e-06 0.00031 20.7 3.7 1 23 225 247 225 247 0.99

4 17 1.6e-05 0.00095 19.2 0.3 1 23 253 275 253 275 0.98

5 17 0.67 38 4.7 0.8 2 23 375 398 374 398 0.93

6 17 1 59 4.1 0.1 3 23 445 466 443 466 0.93

7 17 0.17 10 6.5 0.1 1 23 786 808 786 808 0.95

8 17 0.0042 0.24 11.6 0.2 1 23 915 938 915 938 0.93

9 17 8.2e-05 0.0047 17.0 1.4 1 23 945 968 945 968 0.98

10 17 0.005 0.29 11.4 1.8 1 23 1000 1022 1000 1023 0.96

11 17 0.16 9.2 6.7 0.2 1 23 1311 1335 1311 1335 0.94

12 17 0.0007 0.04 14.1 0.2 2 23 1344 1366 1343 1366 0.96

13 17 0.011 0.63 10.3 0.1 1 23 1373 1395 1373 1395 0.97

14 17 7.3 4.2e+02 1.4 0.9 2 20 1403 1421 1403 1424 0.92

15 17 0.036 2.1 8.7 0.3 2 23 1633 1654 1632 1654 0.95

16 17 0.0094 0.54 10.5 0.0 1 20 1664 1683 1664 1687 0.94

17 17 0.036 2.1 8.7 0.2 1 23 1695 1717 1695 1717 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00013	0.0073	16.4	3.6	1	23	169	191	169	191	0.97
2	17	0.65	38	4.7	5.7	1	23	197	219	197	219	0.98
3	17	5.4e-06	0.00031	20.7	3.7	1	23	225	247	225	247	0.99
4	17	1.6e-05	0.00095	19.2	0.3	1	23	253	275	253	275	0.98
5	17	0.67	38	4.7	0.8	2	23	375	398	374	398	0.93
6	17	1	59	4.1	0.1	3	23	445	466	443	466	0.93
7	17	0.17	10	6.5	0.1	1	23	786	808	786	808	0.95
8	17	0.0042	0.24	11.6	0.2	1	23	915	938	915	938	0.93
9	17	8.2e-05	0.0047	17.0	1.4	1	23	945	968	945	968	0.98
10	17	0.005	0.29	11.4	1.8	1	23	1000	1022	1000	1023	0.96
11	17	0.16	9.2	6.7	0.2	1	23	1311	1335	1311	1335	0.94
12	17	0.0007	0.04	14.1	0.2	2	23	1344	1366	1343	1366	0.96
13	17	0.011	0.63	10.3	0.1	1	23	1373	1395	1373	1395	0.97
14	17	7.3	4.2e+02	1.4	0.9	2	20	1403	1421	1403	1424	0.92
15	17	0.036	2.1	8.7	0.3	2	23	1633	1654	1632	1654	0.95
16	17	0.0094	0.54	10.5	0.0	1	20	1664	1683	1664	1687	0.94
17	17	0.036	2.1	8.7	0.2	1	23	1695	1717	1695	1717	0.95

Sequence Information

Coding Sequence: ATGGCCATGAGGATGCTCTATCGTGGACCGAGCACACGACTGGAGACGTTGATTGAGAAAATTCAGCAAAGTACGCACGGCACCGGCATGATCGCTCCCGGAGCCATCGCCGGTTTGAAAGATTTCGCCCTCGGCCGAGAGCTCTACTCCCCGCAAACGTCCTCCAGCTTTTCGCCCTCGATGTCGGACGGGATGGCGACCCCAAACTCGATCACGCACGACGGTGGTGCCGAACCGGGGCCGGATGCTGCGGGTTGTGGAGAAAAGTCCAGCTTCCGGGCTGCTGGCAGCAACCAGCCACAGATCGGGCACCATCATCACCcgcggcatcatcatcatcatcatctgcacTATCACCATCGGCggtcgggcggcggcggcggcggcggaggccaCCCGAAGGAGGGCAAAACGTCGCGGAGCctccaccacaacaacaacaatagcagcagccaaaacaacaacaatcacacgAACAGTAACAGCAAAAACGTGGACGGCACTTATCACTGTCAGTTCTGCGACAAGACGTTCCCGCGGCTCGGCTACCTCAAGAAGCATGAACagAGCCACACGGAACACATGCCGTTCAAGTGCGAGTACTGCGCGCGGCTCTTCAAGCACAAGCGGTCCCGGGATCGGCACACGAAGCTCCATACGGGCGATCGACGCTATCGCTGTCTGCACTGCGAGGCCGCCTTTTCGCGCAGTGATCATCTGAAGATCCACATGAAAACGCACGACAACCAGAAGCCGTTCCAGTGTACGATCTGCAACCGTGGCTACAACACGGCGGCCGCCCTGACGAGCCACATGCAGAACCACAAAAAGCAGCTGGCGCTCACCGGGAGCCCTAACCTCACGTACAGTCCCCGCTCGACCACCAGTTCCCTGTCGAGCGGCGGAAGCAAGCGGGCCGCAAAGTTCTCGCCCTACGCCAACTCGAACCACTCCGCCGATCCGCTGCTACTTTTGGGCGGACGCACCGCTTCGAAGTTGGTGCTGGCGAAGGGCTCCATCCAGTCGAACGCGAATCGAACACCGACCCCCGGGaatggtggccccggtggtggaggaggagCGAGCAAGGGTGGAGGTGCCGGATCGGAGCCGGATCCGTGCGCCTGTCCGTACTGTACCCGCAAGGACTTTAGCAGCCTGGAGCAGCTCGGTCTGCACGTCCAGTCGATGCACGGTGGCCCTCTGGGCGGTGTTCTGGGTGCCACCGATGGCTACTTCGCTCCGCAGCTCACCCGTGCTCCATCCGTGGCCGGGGGACGCCGTGCTGTGACCCCCGACGGTGGTCACAGCACGACGTACCCTCCCATAGCGTGCGAGTTCTGTACGATGAAGTTCCCCACCGTGCCGCTGATGTTTGCCCACCTGAAGGCGACCCACTTGGACCGGCTGGCGGGCGGAACACCGGCAGGgccgcatcatcatcgattgTCACCGAACGGGACCCATGGAGCCCGATCACCGATGCGCCCGTCCCGGCTGTCCGGTTACCCGTCGCTGGAGCACCTCCAGTTTAACACCAAAAATCTCCTCAGCAGCACCTTCTCATCGCTCTACAGCGGATTGGGGGCACACGGCGCCGGGACGACTGCTCCTGCCACGACCACCATCAAGTCTGAGTCACGGTCCACGGGAACGGTTCGGAGGGAGCACACGGATGCGGAAGATGAAAGTGGGACAGAACCGGATCGAAAGCGTAGTCGAAGAGAAGCACGAAACAAGGACGAAGGCCTAAGCGATGATGCTCCCGAAGACGATGATCCactcgatgacgatgatgaagaggACGGCatcgaggacgatgatgaggacCGTGCGGCTTCTGCGATCGGTGAGGCCTACAGTGAGGTGGCTCAAGAGCCCGAAAGTTCATCCCACGGAGGACCCGAAAATGGAACCCTCATCAAGCAGGAACGGAAGGACACTGCTGGGAGTGCCTCATCCTCATCGGCCCGTTCGTCACCGTACGAGGCGCACCTATCGCACGGGTCCGGATCTCCACTGGCGCAGTCGGCCGCAGTCCGAGAGGGCCTTCCGGCGGAGCAGCTCACACCGACCGATCTCAGCCAGCCGAAGATGAAGCGCCTCAAACTGGAAGCTCcggacgagcagcagctcctggCGGAGGGTGACCCCGCTGGAGGCGCAGTGAGGAAGGGCGGCACCGAGCGTCCACCACCGAGCCAGCAGCGCCGTCCACGGGCCGGAACCGCACGGCGGGAGAGTGAAACGCGGGGCGAACCACAGTCGCTGCAGCATCACCGGATGGCGCCCCAATCGTCCGGCGGGCCGTGCCGCGACCTAGCACCCGCCTCCTCGTTGCCCCCTCCGGGAGCCTACCTTTGCAACCAGTGCAATGCCGCGCTGCCCGATTTCGAGTCCTTCCGGGCGCACCTGAAGGCGCACCTCGAACAGAACAGTGCCAACTGCCTGGCGGCCATGGCCGGCGCTAGTGGCTCCGcgtcgtccgcgtccgccaccaccgccggggccCTGTCGCTCTCGACGTTCCTCTGCCAGCAGTGCGGGGCCACGATGAGCTGCCAGGCCGAGTACGAGCAGCACACGATCGGTCACTTCCTCGTCACCGCCGTCGAGTATCGGTGTCAGGCGGgctctggcggcggcggcggcccaacTTGCCAGTCCGCCCTCGGGAAGGGCGCGTTCGCGAAGGTCGAAGAACTCCACAAACACCTGTACGAGGGCCACATGCAGCTCCTGTACAAGTGCACCGCCTGCGGGGAAACGTTCGACTCCAAGGTCCAGGTGCAGGTCCATTTTGCCGTGAGCCACTCGCTCGAGGTGAAGCTGTACCGGTGCTCCGGATGCGCCGAAACCTTCCGCACGGAGCGTGACTTTCGTCAGCACATTCGCAGTCGCCATCTGACGGGGGGCGCCGTGCAGTGTATGTTCTGCCGTGTGGTCTGCTCGTCGGAACTCGAGATGCACTTTCACCTCGCATCGCACGCCCGGAAATACAAATGTCCTGCATGTCCCGAGTCGTTCCACGTGGAATTTCTACTCGATCGGCACCTCCAAACGCACCACAGTCAGAAGGAACTGGCGTCACCGAACCGGCGTGGCGGGGAGTCCAACTCTAACGCTCAACAGAGCACCGCCAACAACGGCATTCCGGTGtccacgacggccacggcgaccACGACGCCCTCGACCGGTCTGGACTACCTGCAGCTACACGGCCAAATGGCGGCGATGgccgcagcggcagccgccgctTCCGGGGGCTGGCCTACGCTCTACCAGACGGCCAACAAGTTTTACGGCAACCCGCTGCACGTGGACACACTGAGCCAGATGAAGCACCCGCAGCAACTTCTGCACGGGTTCTACGACACCATGCTGGGAAAGGCTgcccagcatcagcaccagcaacatcaCCCGCGTTCTGCGTTCCTTTCGGAGACCGCGACCGTGACGGCCACGAACGttcccaccaccagcaccagcgccgccAGTAACAAATCGAACCCTTTCCTCGGTCTTTCACCTAACGCGGCCGCCAATCCGCTGCTGGGACTGGGCTATGGTTCCACCGGCCCATCTCAGATGGCCGCTTCGGCGAGCGCCCTAAATGGGTTGTATTCTCCCGAGACTAGTGCGGCCCCCAACAGCACCAACGGGACGGCGAACTCCACTTCGGGAAGCTCCAAACTTTACTCCCCAATCAGCATGCTCCACTCGCGGTACACGGCCGAAAACGGTCCCAGTGGGCCCCCGGCCAGAACTGAGTCACCCAGCGGTCAGCTGGGGCTCCCGGGGCTTGAAGGGAAACTGAACGCCCCACCAGCGTGTACCGTTGTTGCCGGGTCGGGGACGAGTAAGGGGTTGACCGGTTCCGCCTCTTCGAGTAGCACAGGGGGCGGCCCTCCACtgacttccggtggcagcTACAGTTGTGGCATTTGCGAGCGCACCGACTTCAGCACCGAAAGTGAGGTCCAAACGCACCGCAAGATCGTGCACAACCTCAAGACGGGCGTCAGTTTGCGGTGCGCGTACTGCAACGGGGATTTCCGATCGAGGAACGAGCTGGAGAACCACATGAAGATTGCGCACAACACGGGCGGCGGCAAGCACAAGTGTTTGATATGCGATGAAATCTTCCCTTCGCCCGCCGTCCTGGCCGAGCACAAGCTGTCCCACTGTAAGGTCGGTGCGTCCGGCCGCTGTTCGCACTGTGCCCTGCCGCTCCCGGATGCGCACACCTTCAAGCAGCATCTCCCGGTCCACCAGGCATCGATCGGTGCTGGTTCGTCAactccggcggctgctggtcCGGCGGTCTCTACGGCCAGTTCCAACACCCTGGTGGCCAGCACCGGTGGTACGGGGGGCAGTGGAGCATCTTCTGCCCCGCCCAACGGTGTCCAAACAGCGAGCGGGACGACGAGTGGCACCAGCGGTGGTTCCGGCTCGGAACAGGATCGGTTCCCGCAGCAATGCATCTGCTGCCGGCAGACGCTAAACTCCGAGTTCGAAATCAGTCTACACGCCAAATTCCACACCAAGTCACCGGACACGAACGAGCGCACGTGCGCCCTCTGCCTGGAACCGCTGCCATCGCAACCGGAAGCGTCGACTAAGATCTGCGATCCGTGCCTCAAGCGACACAACTTCCCGACCAAGCTGCTGTCGATGAACTTTCTcaaaccaccggccacggccacgtccACCAGtgttccggccaccgccgccagtgcACCTATGAGTGCTACCCCCGGTGGAACCCCAGTCGCTACGACAACCCTCGCACCGTCCCACCATGGCGCCGGCGAGCCGTACGGCGGCCATCATCTAATGGCCTCCTCGCCCGAATCCGCACCAATAATGCTTGCGTCGTCTCCGCCGTCGGTGCAGTGTAACCTCTGCAGAAAGGCGCTCCCGTCGGCGCACAAACTGCAGGAGCATCTGATCGATCACACGTTTGCCGGCTGCGAGGAGCGTGGCTACGTGTGCTACCTCTGTTCGGCCGTCTTCACGTCGTCCGCCGGCCTTCAGGCCCACCTTCCGGTAGCTCACTCGAACGCAACCGCCAAACCGTACGACTGCGAGCGGTGCGGTGTTGCGTACTTTTTCCGTGCCGAACTCGAACACCATCTGGCCGAGCACGAGCTGGGACGGCCGGTGCTCGAAGAGTGGCCAGCAGCACTGGCCGTGGGAGGCAGTCACATCAAGCAGGAAAGGGCGGACGAAGAGGAGCTGATCGAAGAATCGATTCTGGAACCGAGAAGGATCGCCGGTGAGGGATCGCTCGATGGTGAGAGGGCTGAAGATCGAAGCGTCGCTGGAGGGAATCAAGAAGATGGGCAGGACGAAACGGGTGCGGATGACGATGACACGGCTCAGAATCAGAATGAACCTCCtccgagcggcagcagcaacaaatccaacgatggcgatgatcgtgatgatgatgatggcgatgaggATCGTCAAGAAGAGATGCTCGTCGAAGACGAAGCAGAACAACCGGAAGATGATGGCGACGtggaagaagaggaagaagagtACATCGAGGTGGAGCACACGGCGCTGGAGGAAGCCCACAAGGAGTCGACCACTCGAACGCCCAACGCGATGGCGATCGGCTACGGGAAGGATCGATCAGCGATACCCGCTTCACCGTCGCTCGTCACCGTCACTGCAACGGAATAA
Protein Sequence: MAMRMLYRGPSTRLETLIEKIQQSTHGTGMIAPGAIAGLKDFALGRELYSPQTSSSFSPSMSDGMATPNSITHDGGAEPGPDAAGCGEKSSFRAAGSNQPQIGHHHHPRHHHHHHLHYHHRRSGGGGGGGGHPKEGKTSRSLHHNNNNSSSQNNNNHTNSNSKNVDGTYHCQFCDKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGSKRAAKFSPYANSNHSADPLLLLGGRTASKLVLAKGSIQSNANRTPTPGNGGPGGGGGASKGGGAGSEPDPCACPYCTRKDFSSLEQLGLHVQSMHGGPLGGVLGATDGYFAPQLTRAPSVAGGRRAVTPDGGHSTTYPPIACEFCTMKFPTVPLMFAHLKATHLDRLAGGTPAGPHHHRLSPNGTHGARSPMRPSRLSGYPSLEHLQFNTKNLLSSTFSSLYSGLGAHGAGTTAPATTTIKSESRSTGTVRREHTDAEDESGTEPDRKRSRREARNKDEGLSDDAPEDDDPLDDDDEEDGIEDDDEDRAASAIGEAYSEVAQEPESSSHGGPENGTLIKQERKDTAGSASSSSARSSPYEAHLSHGSGSPLAQSAAVREGLPAEQLTPTDLSQPKMKRLKLEAPDEQQLLAEGDPAGGAVRKGGTERPPPSQQRRPRAGTARRESETRGEPQSLQHHRMAPQSSGGPCRDLAPASSLPPPGAYLCNQCNAALPDFESFRAHLKAHLEQNSANCLAAMAGASGSASSASATTAGALSLSTFLCQQCGATMSCQAEYEQHTIGHFLVTAVEYRCQAGSGGGGGPTCQSALGKGAFAKVEELHKHLYEGHMQLLYKCTACGETFDSKVQVQVHFAVSHSLEVKLYRCSGCAETFRTERDFRQHIRSRHLTGGAVQCMFCRVVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHLQTHHSQKELASPNRRGGESNSNAQQSTANNGIPVSTTATATTTPSTGLDYLQLHGQMAAMAAAAAAASGGWPTLYQTANKFYGNPLHVDTLSQMKHPQQLLHGFYDTMLGKAAQHQHQQHHPRSAFLSETATVTATNVPTTSTSAASNKSNPFLGLSPNAAANPLLGLGYGSTGPSQMAASASALNGLYSPETSAAPNSTNGTANSTSGSSKLYSPISMLHSRYTAENGPSGPPARTESPSGQLGLPGLEGKLNAPPACTVVAGSGTSKGLTGSASSSSTGGGPPLTSGGSYSCGICERTDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCALPLPDAHTFKQHLPVHQASIGAGSSTPAAAGPAVSTASSNTLVASTGGTGGSGASSAPPNGVQTASGTTSGTSGGSGSEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPEASTKICDPCLKRHNFPTKLLSMNFLKPPATATSTSVPATAASAPMSATPGGTPVATTTLAPSHHGAGEPYGGHHLMASSPESAPIMLASSPPSVQCNLCRKALPSAHKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPVAHSNATAKPYDCERCGVAYFFRAELEHHLAEHELGRPVLEEWPAALAVGGSHIKQERADEEELIEESILEPRRIAGEGSLDGERAEDRSVAGGNQEDGQDETGADDDDTAQNQNEPPPSGSSNKSNDGDDRDDDDGDEDRQEEMLVEDEAEQPEDDGDVEEEEEEYIEVEHTALEEAHKESTTRTPNAMAIGYGKDRSAIPASPSLVTVTATE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -