Basic Information

Insect: Anopheles atroparvus
Gene Symbol: ham
Assembly: GCA_015501955.1
Location: CALTRM010000019.1:1470495-1492641[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2 1.6e+02 1.7 2.5 2 23 122 144 122 145 0.92

2 9 0.0001 0.0081 15.2 0.1 1 23 151 174 151 174 0.96

3 9 7e-10 5.5e-08 31.5 0.9 1 23 180 202 180 203 0.96

4 9 5e-07 3.9e-05 22.5 1.7 1 23 209 231 209 231 0.95

5 9 4.9e-06 0.00039 19.4 5.9 1 23 237 259 237 259 0.99

6 9 0.0012 0.095 11.9 1.3 2 21 267 286 266 287 0.95

7 9 6.1e-10 4.8e-08 31.7 1.1 1 23 885 907 885 907 0.99

8 9 5.5e-07 4.3e-05 22.4 1.6 1 23 913 936 913 936 0.97

9 9 4.7e-05 0.0037 16.3 6.7 1 23 942 964 942 964 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2	1.6e+02	1.7	2.5	2	23	122	144	122	145	0.92
2	9	0.0001	0.0081	15.2	0.1	1	23	151	174	151	174	0.96
3	9	7e-10	5.5e-08	31.5	0.9	1	23	180	202	180	203	0.96
4	9	5e-07	3.9e-05	22.5	1.7	1	23	209	231	209	231	0.95
5	9	4.9e-06	0.00039	19.4	5.9	1	23	237	259	237	259	0.99
6	9	0.0012	0.095	11.9	1.3	2	21	267	286	266	287	0.95
7	9	6.1e-10	4.8e-08	31.7	1.1	1	23	885	907	885	907	0.99
8	9	5.5e-07	4.3e-05	22.4	1.6	1	23	913	936	913	936	0.97
9	9	4.7e-05	0.0037	16.3	6.7	1	23	942	964	942	964	0.99

Sequence Information

Coding Sequence: ATGGGCACAGGCGGTTCCCAGCACAGCGAAAACTACGAGGACGAGTACAATACGTCGAACGAGCTCGACTCCAGcctcggcaaggagcaccagcagcagcagcacctcaaccaccatcaccatctgcacaacagtagcagcaacagcagcagcaacagcagctccggcagcagcaccggcggcgcggaccatcgcagcagccaccaccatcgaacccgcgccagcaaggcgaacgggaacggacgccacgggtcggaaaacgaaggtggaagcagcgatctccaccaccagcagcagcaacagcagcagcagAACTCTTCGGACGTCAAGGAGGACGAAGAGGACGAGCAGGGAATCGACGCGCGCTGTGTCGTCTGTGATCGACAGTGTCACGATATTGATCAACTCGATGATCATCTCGTGATCTCGCACCACTACCCGAAGGACGCCTACAGGTGCGAGCTTTGTCCGAGGGCCTACAGCTACAGGCCATCGTTGCTGCGACATCGAGCGATCGTGCACGGGGAGCTACGGCGCTTTCCCTGTGAAAATTGTCCCAAGGTTTTCACCGATCCGTcgaacctccagcggcacatccggacgcatcacgtgggagcgcgcagtcacgcgtgcccggagtgcggcaaaacgttcgccacctcgtccggcctgaaacagcacacgcacatccactcgtcggtgaagccgttccagtgcgaggtgtgcttcaagtcgtacacccagTTCTCGAACCTGTGCCGCCATCGACGCATGCACGCCGACTGCCAGGTGCAGATCAAGTGCAACAAGTGTGGCGACAGCTTCAGCACCACTACGTCGCTGTCGAAGCACAAGCGCTTCTGCGACTCGACCGCCATCACGCGGCCCCCGCTAGGCGCAGGGCAAACGCACCCCCATCACCCGCATCACCCTCATCACCATCATACGTCGCAGCTGCGCCATCACGAGTTGTACTCGCACCGGCAGCCCCCGGGAAGTGGCCCGCCAGGTACTGGCAGTGCagcagcatcaggtgcagtaggaggaggaggagcaggaggagcaggagcgccagtgtccggaccaggtggagtcgccggcattcatccgttAGCAACCGGCATGGCAACGCCACCGAACCCATTCCTGATGTTCTCCGGGGCGCACGCCTTCTTTGCGCCCGGCTTCCGCCCGTACCCAGGTATGCCGGGAATGTTCCCGCCAACACCCGGCCAGGCGCACCAGTTCCCACTGCCCTTCTTCCCGAAACCGCCAGGGGCGCTGGCTGGTATGTCGCTGGAACCAGAGCGCAAGACTCCGTCGCCACCGTCGCGCGACCATCTCGGCCTGTTCGAGGCAGCCTATGGCCATCAGTCGATGAAGATATCGCCCCCGACGGCGGAGGAAGCCACCAATCCACTACGGCCGTCACCTGCCCGACCCATTCCGGTCAATTTTAACTCGACGGCGGTGACGGCTGCTGCAGCTGCGGCTTCGGTTGCGGGATTACTGTCGGGTGCGAACTCCCCGGGAGCCCTGGGTGGAGAGCAGCTTCTGCACGGAGCTGGCACGGGCCACAACAACAATCACATCAAGGAGAACAACAATCACAACGGCACCAGTTCCTACGGCCAGGCGTCACAGCCGCACCGGGCGTCGAGTCGTAGCGGCTCAGTATTTGCGATGACCACCGACCGGGCCGCTTCCGATGCGGACGAGGAAGTCGATGTGGGCCTCTCTGGTCCGCTTCGGGTGAAGAACTTTTCGATGCGCGCGAACGGTGGTACCGGGCAGGATGCCGGGTCGAAGTCAAACCCAGCGAACTCACCAGGGTTGGTGGACAGCGAGAAGCACTTGCTCCGTCGGAGAAGTCGCACGGTTGATGAGGACGAGTCGTCCGACTCGGAGGACTTCGAAGGCAACAAGGCAAAGAAGGTTAAAAAGGAAGAAGATGGCCCGGCCTCTGAACAGCCGCTAGATTTGAGTCTTTCGAAGAAGATGAAAAACGACTCGGAGGATGGTGACGAGGAGAAGGATGAGACGGATGGGAATCGTAGCTGTAATCGCAGCCCCACGCCAATCGAAGTGGCCAGCCCGGCATCCACACCGACACCTTCGGTACCGACGCCCAGCTCATCGGAGCTTACGACACAGCACCACGATCTGTCGCTTCGTAGACGCGGCGCACGGAATCGAAATGTCTCTTCTATGTCTCCGGCAAAAGTGCCGTCCGCCTCACCCTCGGTAGACGTGTTTGCCCTTCCCAGTCCTTCACCGTCACTCTCCCCCCGTCCCTCACCGTCTCCATCGTCACCGGGAGTCGCAAACACGGGACTGGGCGGTGGCGGTACCGGCCAACAGCATCAGCCCATCTCCTACCCGCGACCGATCTATCCGCTGCTTCTGGAAGCGATGTATCATCGGCCGGGAGCGATGGGTGCATTTCAGCGGCCCGCGTTCAACTTCCTCGACTCGCTCGAGTCCAACCTGGATCTGCTCAAACGCAACCGCCACTACGCCAACATGCCCGGGAAGGCGTTCCACCAGGCTATGCTGCCCGCGGGCTTCGGAGGTCCCGCTGGTGCACCGGGAGTCCCCGGCGGCCCGCCCGGTGTGCCCGGTGCTAGCCTAGCcggcaaggtgaaggatcgctactcgtgcaagtactgcggcaaggtgttcccccggtcggccaacctcacccgtcacttgcggacgcacaccggtgagcagccgtacaagtgccggtactgcgagcgttccttcagcatctcgagcaacctgcagcgtcacgtgcgcaacatccacaacaaggagcgcccgttcaagtgccacctgtgcgagcgctgcttcggccagcagacgaatctcgaccgccacctgaagaaacacgacgcggaCGCGTCCGGACTGGGGCTCGGGTTGGGCGACTCGCCTTCCTCGAACGAGGCCGAGCGAGGGGACGATGTGTTCTTCGACGAAATACGATCTTTCATGGGCAAGGTTACCTATTCCGGGCCGGCGGCTCTGCTCGCCGCCACTGCAGGCAATGGGTTGGCTAGAGCTGCGGAAGTGGACTCCGCAGTGGGCGAAAAGGCGGACGAAGATGAGGGGGACGCCGTTGAATCGACCGAGTTGGTCGAAGACGAAGAGGAGGAAGAGGACGCGGTGAGCAGCGATGGCGAAAGCGATCTGATCAACATCGAATCCGACAAGGATACGGTCAACAATAACGACACTATCGACGGAGCTGGAGTTCGATAA
Protein Sequence: MGTGGSQHSENYEDEYNTSNELDSSLGKEHQQQQHLNHHHHLHNSSSNSSSNSSSGSSTGGADHRSSHHHRTRASKANGNGRHGSENEGGSSDLHHQQQQQQQQNSSDVKEDEEDEQGIDARCVVCDRQCHDIDQLDDHLVISHHYPKDAYRCELCPRAYSYRPSLLRHRAIVHGELRRFPCENCPKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKSYTQFSNLCRHRRMHADCQVQIKCNKCGDSFSTTTSLSKHKRFCDSTAITRPPLGAGQTHPHHPHHPHHHHTSQLRHHELYSHRQPPGSGPPGTGSAAASGAVGGGGAGGAGAPVSGPGGVAGIHPLATGMATPPNPFLMFSGAHAFFAPGFRPYPGMPGMFPPTPGQAHQFPLPFFPKPPGALAGMSLEPERKTPSPPSRDHLGLFEAAYGHQSMKISPPTAEEATNPLRPSPARPIPVNFNSTAVTAAAAAASVAGLLSGANSPGALGGEQLLHGAGTGHNNNHIKENNNHNGTSSYGQASQPHRASSRSGSVFAMTTDRAASDADEEVDVGLSGPLRVKNFSMRANGGTGQDAGSKSNPANSPGLVDSEKHLLRRRSRTVDEDESSDSEDFEGNKAKKVKKEEDGPASEQPLDLSLSKKMKNDSEDGDEEKDETDGNRSCNRSPTPIEVASPASTPTPSVPTPSSSELTTQHHDLSLRRRGARNRNVSSMSPAKVPSASPSVDVFALPSPSPSLSPRPSPSPSSPGVANTGLGGGGTGQQHQPISYPRPIYPLLLEAMYHRPGAMGAFQRPAFNFLDSLESNLDLLKRNRHYANMPGKAFHQAMLPAGFGGPAGAPGVPGGPPGVPGASLAGKVKDRYSCKYCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKERPFKCHLCERCFGQQTNLDRHLKKHDADASGLGLGLGDSPSSNEAERGDDVFFDEIRSFMGKVTYSGPAALLAATAGNGLARAAEVDSAVGEKADEDEGDAVESTELVEDEEEEEDAVSSDGESDLINIESDKDTVNNNDTIDGAGVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107834;
90% Identity: -
80% Identity: -