Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:22247248-22253294[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.0013 18.5 1.7 1 23 270 292 270 292 0.97

2 15 0.008 0.38 10.8 4.5 1 23 298 320 298 320 0.96

3 15 4.7e-05 0.0023 17.8 0.1 1 23 510 532 510 532 0.98

4 15 0.44 21 5.3 0.3 1 23 538 561 538 561 0.96

5 15 0.23 11 6.2 2.4 1 23 594 617 594 617 0.93

6 15 0.003 0.14 12.1 0.0 2 23 700 721 699 721 0.94

7 15 0.0072 0.35 10.9 0.1 2 23 732 754 731 754 0.92

8 15 0.0034 0.16 11.9 0.9 2 19 762 779 761 780 0.95

9 15 0.008 0.38 10.8 8.9 1 23 789 811 789 811 0.97

10 15 0.03 1.5 8.9 0.8 2 23 817 838 816 838 0.97

11 15 1.3e-06 6.2e-05 22.7 1.3 1 23 844 866 844 866 0.98

12 15 0.0011 0.052 13.5 0.2 1 23 872 894 872 894 0.97

13 15 2.9e-05 0.0014 18.5 0.1 1 23 900 922 900 923 0.95

14 15 0.048 2.3 8.3 0.1 1 23 937 959 937 959 0.97

15 15 1.7 84 3.4 2.3 1 20 1570 1589 1570 1592 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.0013	18.5	1.7	1	23	270	292	270	292	0.97
2	15	0.008	0.38	10.8	4.5	1	23	298	320	298	320	0.96
3	15	4.7e-05	0.0023	17.8	0.1	1	23	510	532	510	532	0.98
4	15	0.44	21	5.3	0.3	1	23	538	561	538	561	0.96
5	15	0.23	11	6.2	2.4	1	23	594	617	594	617	0.93
6	15	0.003	0.14	12.1	0.0	2	23	700	721	699	721	0.94
7	15	0.0072	0.35	10.9	0.1	2	23	732	754	731	754	0.92
8	15	0.0034	0.16	11.9	0.9	2	19	762	779	761	780	0.95
9	15	0.008	0.38	10.8	8.9	1	23	789	811	789	811	0.97
10	15	0.03	1.5	8.9	0.8	2	23	817	838	816	838	0.97
11	15	1.3e-06	6.2e-05	22.7	1.3	1	23	844	866	844	866	0.98
12	15	0.0011	0.052	13.5	0.2	1	23	872	894	872	894	0.97
13	15	2.9e-05	0.0014	18.5	0.1	1	23	900	922	900	923	0.95
14	15	0.048	2.3	8.3	0.1	1	23	937	959	937	959	0.97
15	15	1.7	84	3.4	2.3	1	20	1570	1589	1570	1592	0.92

Sequence Information

Coding Sequence: ATGAACCACAACAACGCATTGCCTCCGCTTTGGCAAGTGGCAACTACTACCGGCGGACACCCGACGCGAATGAACAGCAGTGCCGGCAGCGGCACGAGCAAACTCACCGCCGGAAGCATTTCCTCTGTGAAGTACGTGTCTAATGCACGGCCTACCATGAAAATCATCAACATCCCCAACCAGCAGCAAGCGTCGATGACGGCCACCAGCGATGGGACGCTGCTTTACGGCACGTCCATCGGAGGAGCCGGTTCGTATCTGACAGTGACGAACGAGCAGCGGCAAATGCAGCCGGCGCCACAGGTACGCCGACCGGtgacaaccaccaccaccaccacccatgcGGCACTGCTGAGCGAATCCATCCTGCTGCAAACGCCGGACGGCCGGGAGTACCTCGTGGACGAACGGTCGATACAGAACATCGATCAGATACCGCCGGAAAACTTGATCTACATGACCGCTTCCGAAGCGCTGTCGGTGGTCGATGCGGATGACGTCGGCCAGCTCGCGATTGTGGACGAAAGTCAGCTCGCGCTGCACGATTACGTGGTGCCGGCGGAGGCGGCGATCGATCAAACACAGCACCAAGTACAAGACCAGCCCGCCACCTCCGTCGAGGCACAACAGTACGCGGAAGAGTGCGAAGTGACGGAGGAAGTGATTACGGACGATTGGGTGCAGCCGCAGGGCGAAGAGTGCGTGCAGGTGACGGTCGACCAGCTCGGCGTGAGTGCGGTCGTGGTGCAGGAGGAGGACGACATTTCCGTCCCGCTCGACCAGGACCAGTACACGCTGTCGCGCCCGTACCCGTGCGATTTCTGCAGCCGGCGGTTCCGCAAGAAGAGCAGCCTGCAGAACCATCTGATGGCGCACTCGAACGATCGGCCGCACTGTTGCAACCTGTGCGGGGCACAGTACAGCCACCGGGCGGATCTGATCAACCATCTGAAGCAGCACGCGTACTCCGTGGCGGAGCAGGACGAGCTGGCGCTGCGCAGTGACCAGGAAGCGGAatATGATCTGCCCGATCTGGGGCACACATCCTCCGGGGGCGGCGGCCATAGCATGAAGCATCGGTTGCGGCACTCGAGCGACGACGAAGACATGTACATCCAGAACTCGATGGTGAGCTACAACTCGCAACCACCGATGCAGCTGATTTCCACCACGCATTACGGTGCTTCGTCCTCGTCGACGGTCGGCTCTTCTTCGTACGCGCATGACGTACCGATGGAGCAGTCGCCTTACCTCGAGAGCGTTCCACCCGTGCTGGAGCAAAAGTACGCGCACGGCAAAATGGATCCGACCGGCCCGGCAACACTTTCCACCACCGGCAAACGTACGCCGCGGAAAAAGCAATCCCAAACCACCCAGGATACGCGAACGGCACGGACAAAGCCAGTGTTTGCCTCGAAAGTCGGCAGTCGGCAGATTAAAAAAGAACCCCTGGAGCATGGGGAAGGTGGTAACGCCATATCATCGCCACCTCCCACGAGGACGGTCGCAGCGGACTGGCGCAAACCGTTCGTCTGTCAGCAGTGTGGCGCATCGTTCGCGCGAGAGAAAGCTCTCCTTTCGCACGCCCGCACCCATGCCGGCAGCACGCGCTACGATTGCGCACTGTGCAATGCGCATTTTTGGGAGCAGTCGCTGCTGCGGGACCACGTGCAGCGTGCGCACCCGGCGCAGGAAGCTTGGGTGGCCGACCACGAGCCTTACGGCAGTGCGCACGGAGCGATAGAGCTGCCGGTggtgaccaccaccaccaccaagcagTACAATTGTGATAGCTGCAGTGCAGTATTCTTCCAGCTGGACCAACTACTGAACCATACGCACCACGCGCACGGCACCttcgagcagcaacagcaatcgAGCTCTAATCGTAGTGTGCTGGTAAAGCAGGAACTGCTGCAAACCTCCAGCAAAGTGGAGCTGGAAAGTGACCGTGAAGCGGAAGCTACCGACCAGGAAGCGgccgaggaggacgaggaagaGGAGGGCGAAGAGTACGACAATCTCGAGTACACAATCGAACACTACGAGCaggcgccgccgccgcagcgtTCGAACGAACCCGACCAGTCCGCGCTGACGTGTCGCGATTGTGGGGAGTCGTTCGACAGCGCGATGGACTTGCTCGACCACAGTGAGGTGCACGGTGGTGGCGCCGCCCAGTACGAACCGCTCGAGTGTCAGCTGTGCGGGGAGAAGTTCCCGGACGAGGCCAACATCAAGCAGCACGTGCAGGACCGGCACCGGGACGAGCTGACCGCAACGTCGTGCGCGATCTGCGGCAAGCGCTGCAAAAGCCAAACCACGCTGATGAAGCACGCGTGGGACCATTCGCGCGAGCGGGCCCACTCCTGCTCGAAGTGTGGCAAAACGTTCCACCACATGACGCGGCTGAAGCGGCACATGGACTCGCACCGCAACAAGGCCGTGCGGTGTGAGGTGTGCAAGGAAGAGTTCCCGGACGGCCGGACCCTGATGAACCATCGCCATTCGCACACGAAATCGAACGAGTATCCGTGCCACGAGTGTGGCAAAACGTTCGGCTCGCGCTCGTCGCAGCAGATCCACATGCGCATCCACACGGGGGAGCGGCCGTACGCGTGCCGGTTCTGCTGGAAAGCGTTCGCCGACGGGGGCACACTGCGCAAGCACGAGCGCATTCACACGGGGGAGAAACCGTACGCGTGCCCCGTCTGCCCGAAAGCGTTCAATCAGCGCGTGGTGCTGCGCGAACACATCCGGGCGCATCATTCGCAGGCCGACGCGAAGCGCGGATCGCCGGATCAGCCGTACTACTGTACGGTGTGCAGCTCACCGTTCGGCACGACCGCCGATCTGGTGCAGCATCTGATCGAGCACAGTGACACGAACACGGCGATGAAGCGCAAACCGCCCACCTTCCCGCGCAAGTACAAGCGGCGCCGAAAGCTGAAACCGCACGAGCTCGAGCGGCTGCAGAGCGGCCGGCGGAAGCAGAAATCCAAGCGCCAGATGGAcaacgaggaggaggaggaggaagaggaggaggacgatgacgatgggaGTGGGGGTAGTGGGAATCAATTCGAGGACGGCACGACAGCGCGCACAACGGATCGCACGGTGGTGGAACGTGCGCGCGGCGATGGCAAACCAACCGGCTCCTCGTTCGTTCGCTACCATCCGGACGGGACGCGCAAAACAAGCACGCGCGAAATGTACCTTGAGTATGACGACATGGGAGGAGGGAGTGCCTCACATGCCCCCAAGGCATCCTCGCAAGGTATGCTGGACGTCAATGGGATCAATCTGCTGAGCaatgttgtgctgctgcacgGACAGCAGGAAGAGCCGTCCCAcgcgcacaacaacaaccatctgCCCGAATCTCCTCCCCGGCACATGTTCGGGGAGTTGCCCAAAGCGAAGCAGCAACCACCGGGAAGTTCGCGCATGATTTACACCCAAAAATCAACCACAAAAGCAGCCCCAGCGTCGTCCCGCAAAACGCCATCCGCCCGGAAACGGCCCGCCGCCAAAGAGCAGCGCCCGGCGGCagcgccaccgccgccggtgAAGCTGGAACCCGCCGAGGATGATCCTGCCATCGCGATGGAAGCGTTGTTCCGCGGGCGCAAACGGAACGCTTCACTGCTGCCCGAGATACCGCCGCACCGGATCTCGTCCGTCGGCTTCCCGCTGCTGGACGATGGCAACACGGACGACCCGATGGATGAGCCGGAGCAGCGGGCGCGCCGCAGTACCGCCTCGTTCAGCGCCTCGGAGGACGATCTGCTCAGCCAGCAGCTGCTGATGGAGATTTCGCACAAGAGCAAGTACACCGAGCGGTTCAACAGTGACACGCTGAACGATCTGGAGGAAATACTCCGCTCGCCCGTCAAGGGTGCCGGTTCGCCGGCACTGGCCAAACGTGCCACGACCGTTCCCTCCACCAGTGCTGCCGGtaagaagcaacagcaaagtGCTGCTGCCGCTAAAAAGCCAACCAGCCAGCGTAAGCGAACGGCAGCACCGAAAGCAAAGGCTGCGGCGAAGGCGAAGAACAAACCTGCTGCTTCCCCCACTGCCAGTGGCGCCGGTTCCACCAGTAGCAGGCAGCCACCACAAAAGCCAGTGGAAAAGCGAGCGGCCCGAGAACCGCCGGCAGTGTTGCGCAGTCAGCGGCTTACGCGCCGCCAGCTCGAGCGCGAGGTGAACTTTCTCAAGGAAGCGTATGACGCCGGTGAACCGGTGCACGAGGCAACGGCTGATGGGTCCGGTGGCTCATCGTCCGTGGCGGTTGTAAAAACAGAAGCGGTCGATAAACGCTCCTTGCTGGATGGCGCCGCGACCAGTGTGACTGAGGACCGACCGGACAGTTCCGAACGCTTGGCAGCGATGCTGCTCAACGATGGTCTTCCGGACGAATcggacagcagcaacagcagcggtgAGGGAAGTCGCCGTAGCAGTGTGATGTCCACCGCAGCGCGACAGACGCATAAGTACGGTCCGGAATCGTACGCAGAAGAATTGCAGATGATGGAAACGGCGGAGGAGGAACATGTGGTAAAGCAGGAGGATGACCAAGGGCAGGGTGAGCATCACTACGAGCTGGGTGACGACGATGTGGGTGAACTGTATCTGGATGATAACGACACTACTACctcagcaacaacaccagccGCAGCCATTGGTGACGAACCGTTGCATCGATGTTCGATATGTTGCGCCTGCTTTGATGATCGGGCCCAGCTCATCCTGCACGTTCCGGTGCATATTTAG
Protein Sequence: MNHNNALPPLWQVATTTGGHPTRMNSSAGSGTSKLTAGSISSVKYVSNARPTMKIINIPNQQQASMTATSDGTLLYGTSIGGAGSYLTVTNEQRQMQPAPQVRRPVTTTTTTTHAALLSESILLQTPDGREYLVDERSIQNIDQIPPENLIYMTASEALSVVDADDVGQLAIVDESQLALHDYVVPAEAAIDQTQHQVQDQPATSVEAQQYAEECEVTEEVITDDWVQPQGEECVQVTVDQLGVSAVVVQEEDDISVPLDQDQYTLSRPYPCDFCSRRFRKKSSLQNHLMAHSNDRPHCCNLCGAQYSHRADLINHLKQHAYSVAEQDELALRSDQEAEYDLPDLGHTSSGGGGHSMKHRLRHSSDDEDMYIQNSMVSYNSQPPMQLISTTHYGASSSSTVGSSSYAHDVPMEQSPYLESVPPVLEQKYAHGKMDPTGPATLSTTGKRTPRKKQSQTTQDTRTARTKPVFASKVGSRQIKKEPLEHGEGGNAISSPPPTRTVAADWRKPFVCQQCGASFAREKALLSHARTHAGSTRYDCALCNAHFWEQSLLRDHVQRAHPAQEAWVADHEPYGSAHGAIELPVVTTTTTKQYNCDSCSAVFFQLDQLLNHTHHAHGTFEQQQQSSSNRSVLVKQELLQTSSKVELESDREAEATDQEAAEEDEEEEGEEYDNLEYTIEHYEQAPPPQRSNEPDQSALTCRDCGESFDSAMDLLDHSEVHGGGAAQYEPLECQLCGEKFPDEANIKQHVQDRHRDELTATSCAICGKRCKSQTTLMKHAWDHSRERAHSCSKCGKTFHHMTRLKRHMDSHRNKAVRCEVCKEEFPDGRTLMNHRHSHTKSNEYPCHECGKTFGSRSSQQIHMRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHSQADAKRGSPDQPYYCTVCSSPFGTTADLVQHLIEHSDTNTAMKRKPPTFPRKYKRRRKLKPHELERLQSGRRKQKSKRQMDNEEEEEEEEEDDDDGSGGSGNQFEDGTTARTTDRTVVERARGDGKPTGSSFVRYHPDGTRKTSTREMYLEYDDMGGGSASHAPKASSQGMLDVNGINLLSNVVLLHGQQEEPSHAHNNNHLPESPPRHMFGELPKAKQQPPGSSRMIYTQKSTTKAAPASSRKTPSARKRPAAKEQRPAAAPPPPVKLEPAEDDPAIAMEALFRGRKRNASLLPEIPPHRISSVGFPLLDDGNTDDPMDEPEQRARRSTASFSASEDDLLSQQLLMEISHKSKYTERFNSDTLNDLEEILRSPVKGAGSPALAKRATTVPSTSAAGKKQQQSAAAAKKPTSQRKRTAAPKAKAAAKAKNKPAASPTASGAGSTSSRQPPQKPVEKRAAREPPAVLRSQRLTRRQLEREVNFLKEAYDAGEPVHEATADGSGGSSSVAVVKTEAVDKRSLLDGAATSVTEDRPDSSERLAAMLLNDGLPDESDSSNSSGEGSRRSSVMSTAARQTHKYGPESYAEELQMMETAEEEHVVKQEDDQGQGEHHYELGDDDVGELYLDDNDTTTSATTPAAAIGDEPLHRCSICCACFDDRAQLILHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101120;
90% Identity: iTF_00101120;
80% Identity: -