Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:78019858-78027704[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.8 1.8e+02 2.4 0.0 1 11 264 274 264 280 0.86

2 16 0.016 0.77 9.8 0.5 1 23 289 312 289 312 0.94

3 16 0.025 1.2 9.2 3.8 2 23 319 340 318 341 0.93

4 16 1.4e-05 0.00065 19.5 4.9 1 23 347 370 347 370 0.97

5 16 9.4e-06 0.00045 20.0 1.2 1 23 375 397 375 397 0.98

6 16 0.00019 0.0089 15.9 0.8 1 23 403 425 403 425 0.98

7 16 6.4e-06 0.00031 20.5 2.2 1 23 430 453 430 453 0.98

8 16 0.0072 0.35 10.9 0.3 3 23 721 742 719 742 0.97

9 16 0.0012 0.059 13.3 4.4 2 23 749 770 748 770 0.97

10 16 6.5 3.1e+02 1.6 0.1 3 12 1096 1105 1095 1113 0.83

11 16 0.0033 0.16 12.0 1.0 1 23 1119 1142 1119 1142 0.92

12 16 0.00092 0.044 13.7 1.3 2 23 1149 1171 1148 1171 0.92

13 16 0.015 0.73 9.9 3.8 1 23 1177 1200 1177 1200 0.96

14 16 1.9e-05 0.00089 19.1 0.6 1 23 1205 1227 1205 1227 0.96

15 16 0.022 1 9.4 3.6 1 23 1233 1255 1233 1255 0.96

16 16 0.00018 0.0084 16.0 0.5 3 23 1262 1283 1260 1283 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.8	1.8e+02	2.4	0.0	1	11	264	274	264	280	0.86
2	16	0.016	0.77	9.8	0.5	1	23	289	312	289	312	0.94
3	16	0.025	1.2	9.2	3.8	2	23	319	340	318	341	0.93
4	16	1.4e-05	0.00065	19.5	4.9	1	23	347	370	347	370	0.97
5	16	9.4e-06	0.00045	20.0	1.2	1	23	375	397	375	397	0.98
6	16	0.00019	0.0089	15.9	0.8	1	23	403	425	403	425	0.98
7	16	6.4e-06	0.00031	20.5	2.2	1	23	430	453	430	453	0.98
8	16	0.0072	0.35	10.9	0.3	3	23	721	742	719	742	0.97
9	16	0.0012	0.059	13.3	4.4	2	23	749	770	748	770	0.97
10	16	6.5	3.1e+02	1.6	0.1	3	12	1096	1105	1095	1113	0.83
11	16	0.0033	0.16	12.0	1.0	1	23	1119	1142	1119	1142	0.92
12	16	0.00092	0.044	13.7	1.3	2	23	1149	1171	1148	1171	0.92
13	16	0.015	0.73	9.9	3.8	1	23	1177	1200	1177	1200	0.96
14	16	1.9e-05	0.00089	19.1	0.6	1	23	1205	1227	1205	1227	0.96
15	16	0.022	1	9.4	3.6	1	23	1233	1255	1233	1255	0.96
16	16	0.00018	0.0084	16.0	0.5	3	23	1262	1283	1260	1283	0.97

Sequence Information

Coding Sequence: ATGGAGCTAGTTGTGCAGGAAATGTGGAACTTTTGTCGATTTTGTTTAAGCCAGGACGAAGATCTTCTTATCCCGATCAGGAACGCACTGGACGAGCACGTCACCGTCGACAATATAGAACGATTCACGGGCATCGCTATCGAACCGGACGAAAACATTCACGATGCCATTTGTACCGATTGCTCCAACCGATTGTACACGTATGCTGTCTTCCGGCGGTCTTGCTTAAGGAACGATGCCTATTTACGTAAAATTTACCCACAAATGTGTGCTGATGACATACTCGATGAAGTAGATGCTGCAGCGGCTAATCACAGTAACGACCCGTGTGTTAACCGGAAGTTGGAAAGTGTCGTTCCGAAGGCATCCTCTTCCCAAGCGACGAGTGTGtcagaagaagatgaagaagaagaagaggaagaagaagaagaagaaggagaagaaggagaagaagaagaagaggaagaaggatATTCATGCTTCTCAAGCGAACAGCCCACCACACAATCGATGGTGCTCGCAAACCCCTCTCCCCCACCATCGGTCGATCGTGGCGTGAAGGATGAGCTAGTGGAAGAAGAACTGTACTCGGCTAACTACATCGCACCGGGCGAAGATTTGGACGATGACGCGCGGGGCTCCAGCGACGACGACAGCTTCATAGCGGAAATGTACAACGCCATCATGCGCAAACCGCAACGAGCCTACACGCAGTCGAAAATTGAGCAAGAGTACATTTCGAACGAAATGTACCACCTGCTGGACCTGTCGAAGTATCGGCGCCAGCGGTATCTGTGCGAAATGTGCGGGAAGATGGTGAGCGATATCGTGTCGCACATCGTCAGCCACAAGCAGGAGGCCCGGTACGCGTGTCCGCACTGTCCCGTCCGCATGACGCACTCGGCCAACATGATGCGGCACGTGCAGGCGGTACACGAGCGCAGGATAGTGAAGACGTGCAAACCATGCGGCAAAGGATTTACGCACAAAAATGGCTACGATTCGCATATGCTATCACACCACGGCATCGGGACGCAGCATGAGTGCAAAGTGTGCGGAAAGATGTTCAACCACAGGAGCAGCATGAGAGAGCACATCAGAAGGTATCACGAAATGGAGAGTTACAGCTGCTCGTTGTGTGACAAAACGTTCAAAATGAGGAGAGCTCTTCAAAATCATCAGCTAGTTCACAGCACGGAAAGGCCGTACGCATGCCCGCGGTGTCCGAAGCAGTTTAAAAGCGCCAAAACTAGAGCCACCCATTTACGCACGCACAGCGGCATCCAGTACAAATGCACGCTGTGCGACAAATCCTATCGGTACAAAGCGCTGCTTAATATACACCGTCGTAAAATGCACCCGACGGAAGGTCTTAGCAATGAGTTCTGCCTGTGCGAGGACGACCAGCGCCTCTGTCCGATCACAGCAACCTTCAGTGCTTCACTTACGCACAAAGATGTGGAACGATTTACCGGAATACAGATAAACCCAGACGAGGACTGCGCGACCTACGCCATCTGCCACGAGTGCGCAAACAGGCTAAGAACGGCTGCGGAGTTCCGATGCACCTGCTTAAACAACGATATAAAATTCCAGGAGCTGTTCATGACGCTCATTTACAGTGCAGAGCGCGCGTACTATGAAGATTGGGAGTGTGAAGAATTGTCCGACGACGATGAGAAACAGGAGAAGGAGCAAATGAGCGATCAAACAACCGAATTCGAAGCACTCACACTGGATGGGTACAGTTACGATGAACAAGAGCGCAATCCAATCAGCTCGCCAGAATGCCAGGACGATGATGCAGAGTTGTACTCTGCGAACTATATTGCGCCCGACGATCCGTACCATTCGGAGACAACTGACGAAAGTCGAACAAATCCCCTCTTGCTAAGGTCGGCAAAACAGAGAGGAAGTATACAAAATGGCGCCGATCTGCTTGAAAACGTGCAGTCCAACGTTCGCCGATCGGGCAAGAGCGAGGGAAAGAAGCGGAAAATCCTAGATGCATCGATCGTTGATCAGAGCCCGGGCTACTACATTAAAAAGTACAAAGCGGGCATCCGTGTACGCCCGAAGACGCTCTGTGAAGTGTGCGGCGTGTTCGTGATCGGGGTACGCCGCCATCTGCtaaatcatcggcaggagtCACTGTACGGGTGCCCGCATTGTCCAGTGAAGATGAAGCAGAAGAGCAACATCATGGCCCACATTAACACGGTGCACTTCAAAACGGTCGGCAAAACGTGCGGCATCTGCGGGAAGGGCTTCGTACACCACAAAACGTATCGATATCATATGTACACGCATGTGCTGGAAAAGCAACCTTTTCTCTCGTCTCCGAACCCGTTCGGAACCACCCTGTACGATACAAATGGGCGCCGTTTTGACAACCCGTTTCGTTGGAAatttgtttaccaacaatCCTTTCCAGATTTCGCCCGCAGTATGGCGATCGCCTCGCAGGGATTGCTAAACGTTTGCCGATTCTGTTTGTCCCAGGAAGATGAACGAATCATTCTGCTCGATCAGATCCTGGACGCGTCGCTCTCAATCGAAAATGTGCAACAGTTAACAGGAATTGAAATATGTACGGATCAAACAACGACGCAGGCGGTATGCTTGGAGTGCACCAGCAAGCTTAAAAAGGCTTCGGCTTTCCGGAACAACTGCATCAGCAACGACTACCTGTTCCGGCAGCTCTGCTCACGGTCGCGTTTCACCGTCGTCCAAGGTGCTACTGATGATGTCCAAAACGATGATTCTGTCCTGGAGGATCCACTAGATTTTGAGATCACTGATAATACGATAAACGATGGTTTCTCGGCTACTGATGATGAAACGGACTTCGaacaggatgatgatgatgagccaaatcgaacgcgaacgaaacgaaatacAGACTCCACCAACGATGATACAATGGAGTACAGGGAAGAGGTCATCGCTTCCGTTGATTATGATGACGGCACAGCTATCTCGGAAACCAGTCCGCCTAAACGCCATGAAGACGAACCAACGGTAGCAACGATGCAGCAGTCGACGGAACAAGACGATACGCTCTACTGTGCCAACTACATAGAGCTGGGTGAACCGCCCACTGATGGCGAGGAAGCCGTAGCTGCATTAAGTAAGAATGATAATCTTACCTGCTGGACTGGTTCACGCACCAGACGAGCCAAGCTCGTGTTAGTGCGGAGCGGACAAGCTGGCGGTAATACTCGCGCTGCCACCTCGACGAGCATTCTATTTCGCCGCACCAAGCGCAAGCGTCAGAAGCCACTCTGCGAAACGTGCGGCAAGGTGGTGACAAACATTGCAACGCACCGCGCAACACACAGCAAGGAGATGGGCCACGCCTGTCCGCACTGTTCGATACGGATGAGCAATTCATCGAATCTGCTGCGCCACGTACAAGCCGTCCATCTCAAGGTGAACGTAAAGACGTGCGAAATCTGTGACATTGGGTTTACCCATTACTCTACCTACCGGTCGCACATGTACGCACAGCACGGAATCGGTGAGCTGCACGAGTGCCGGGTGTGCTCGAGAACGTTCCCGGACGCCTGTGTGCTGCGAAAGCACGTGAAACGGTTTCATGGTGTGCAGGAGCACGCCTGTCCCATCTGTGGCAAACTATTCAAGATGCTCGACATGCTCAAGCGTCACCAGCTAGTCCATTCTAAAGAGCAGCCGTTTATGTGCAGCCAATGTCCGAAGCGCTTCAAAAGCGACACCTCCAGGAAAAAGCACGAGTTCACCCACAGCGGCATCCTGTTCGGTTGCTCCCTGTGTGGCAAAACGTACCGGTACAAGTATCTCGTCAATGCGCACATCAAAAAGGAGCACCCGCTTGAAGGTGGCGAAAACGACGCAGAAACGCCACCACACTGCGAGGGTACGACGGAAGGGGAATCGACCGTTATCGAGTATGGCGAAAACTGA
Protein Sequence: MELVVQEMWNFCRFCLSQDEDLLIPIRNALDEHVTVDNIERFTGIAIEPDENIHDAICTDCSNRLYTYAVFRRSCLRNDAYLRKIYPQMCADDILDEVDAAAANHSNDPCVNRKLESVVPKASSSQATSVSEEDEEEEEEEEEEEGEEGEEEEEEEGYSCFSSEQPTTQSMVLANPSPPPSVDRGVKDELVEEELYSANYIAPGEDLDDDARGSSDDDSFIAEMYNAIMRKPQRAYTQSKIEQEYISNEMYHLLDLSKYRRQRYLCEMCGKMVSDIVSHIVSHKQEARYACPHCPVRMTHSANMMRHVQAVHERRIVKTCKPCGKGFTHKNGYDSHMLSHHGIGTQHECKVCGKMFNHRSSMREHIRRYHEMESYSCSLCDKTFKMRRALQNHQLVHSTERPYACPRCPKQFKSAKTRATHLRTHSGIQYKCTLCDKSYRYKALLNIHRRKMHPTEGLSNEFCLCEDDQRLCPITATFSASLTHKDVERFTGIQINPDEDCATYAICHECANRLRTAAEFRCTCLNNDIKFQELFMTLIYSAERAYYEDWECEELSDDDEKQEKEQMSDQTTEFEALTLDGYSYDEQERNPISSPECQDDDAELYSANYIAPDDPYHSETTDESRTNPLLLRSAKQRGSIQNGADLLENVQSNVRRSGKSEGKKRKILDASIVDQSPGYYIKKYKAGIRVRPKTLCEVCGVFVIGVRRHLLNHRQESLYGCPHCPVKMKQKSNIMAHINTVHFKTVGKTCGICGKGFVHHKTYRYHMYTHVLEKQPFLSSPNPFGTTLYDTNGRRFDNPFRWKFVYQQSFPDFARSMAIASQGLLNVCRFCLSQEDERIILLDQILDASLSIENVQQLTGIEICTDQTTTQAVCLECTSKLKKASAFRNNCISNDYLFRQLCSRSRFTVVQGATDDVQNDDSVLEDPLDFEITDNTINDGFSATDDETDFEQDDDDEPNRTRTKRNTDSTNDDTMEYREEVIASVDYDDGTAISETSPPKRHEDEPTVATMQQSTEQDDTLYCANYIELGEPPTDGEEAVAALSKNDNLTCWTGSRTRRAKLVLVRSGQAGGNTRAATSTSILFRRTKRKRQKPLCETCGKVVTNIATHRATHSKEMGHACPHCSIRMSNSSNLLRHVQAVHLKVNVKTCEICDIGFTHYSTYRSHMYAQHGIGELHECRVCSRTFPDACVLRKHVKRFHGVQEHACPICGKLFKMLDMLKRHQLVHSKEQPFMCSQCPKRFKSDTSRKKHEFTHSGILFGCSLCGKTYRYKYLVNAHIKKEHPLEGGENDAETPPHCEGTTEGESTVIEYGEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -