Basic Information

Insect: Anopheles arabiensis
Gene Symbol: ZFY
Assembly: GCA_016920715.1
Location: NC:79249481-79261195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1.4 66 3.7 0.5 3 23 218 239 218 239 0.96

2 20 4.4 2.1e+02 2.1 0.4 6 23 248 265 248 265 0.91

3 20 0.00039 0.019 14.9 0.6 2 23 270 291 269 291 0.94

4 20 0.002 0.093 12.7 9.2 1 23 300 322 300 322 0.99

5 20 0.0017 0.081 12.9 0.1 2 23 326 348 325 348 0.96

6 20 0.012 0.56 10.3 1.0 3 23 356 376 354 376 0.96

7 20 0.022 1 9.4 0.2 2 23 386 408 385 408 0.95

8 20 0.02 0.94 9.5 1.1 2 23 415 437 414 437 0.95

9 20 3.2e-05 0.0015 18.3 1.9 1 23 443 465 443 465 0.98

10 20 0.0014 0.069 13.1 1.5 1 23 471 494 471 494 0.97

11 20 0.71 34 4.6 0.0 2 23 712 734 711 734 0.95

12 20 4 1.9e+02 2.3 0.1 6 23 743 760 743 760 0.93

13 20 0.00072 0.034 14.1 2.4 2 23 765 787 764 787 0.93

14 20 0.00058 0.028 14.4 1.5 1 23 795 817 795 817 0.98

15 20 0.00082 0.039 13.9 0.7 2 23 821 843 820 843 0.94

16 20 6.9e-06 0.00033 20.4 0.5 1 23 849 871 849 871 0.96

17 20 0.0008 0.038 13.9 3.0 2 23 881 903 880 903 0.94

18 20 0.034 1.6 8.8 0.4 1 23 910 933 910 933 0.96

19 20 1.3e-07 6.4e-06 25.8 0.6 1 23 938 960 938 960 0.98

20 20 0.097 4.7 7.4 5.0 1 23 966 990 966 990 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1.4	66	3.7	0.5	3	23	218	239	218	239	0.96
2	20	4.4	2.1e+02	2.1	0.4	6	23	248	265	248	265	0.91
3	20	0.00039	0.019	14.9	0.6	2	23	270	291	269	291	0.94
4	20	0.002	0.093	12.7	9.2	1	23	300	322	300	322	0.99
5	20	0.0017	0.081	12.9	0.1	2	23	326	348	325	348	0.96
6	20	0.012	0.56	10.3	1.0	3	23	356	376	354	376	0.96
7	20	0.022	1	9.4	0.2	2	23	386	408	385	408	0.95
8	20	0.02	0.94	9.5	1.1	2	23	415	437	414	437	0.95
9	20	3.2e-05	0.0015	18.3	1.9	1	23	443	465	443	465	0.98
10	20	0.0014	0.069	13.1	1.5	1	23	471	494	471	494	0.97
11	20	0.71	34	4.6	0.0	2	23	712	734	711	734	0.95
12	20	4	1.9e+02	2.3	0.1	6	23	743	760	743	760	0.93
13	20	0.00072	0.034	14.1	2.4	2	23	765	787	764	787	0.93
14	20	0.00058	0.028	14.4	1.5	1	23	795	817	795	817	0.98
15	20	0.00082	0.039	13.9	0.7	2	23	821	843	820	843	0.94
16	20	6.9e-06	0.00033	20.4	0.5	1	23	849	871	849	871	0.96
17	20	0.0008	0.038	13.9	3.0	2	23	881	903	880	903	0.94
18	20	0.034	1.6	8.8	0.4	1	23	910	933	910	933	0.96
19	20	1.3e-07	6.4e-06	25.8	0.6	1	23	938	960	938	960	0.98
20	20	0.097	4.7	7.4	5.0	1	23	966	990	966	990	0.96

Sequence Information

Coding Sequence: atgaaaaatgaacCCCAAACGTGTCGCTTGTGCTTGCGCAGTTCGTTCCGTGGTCGCAAAATTGCCATCTCGAACGGAGACTTTCAACAGAAGCTAAAAGCTGTGTTTTCGTTCGATATTGCGCCAGCTGAAAATCTCCCGGCCGATGCATGCCGTGGATGCCGAGAAACGGTCGAACAGTTCTACGAGTACAGTGAGAAAGTTCGAGCCAACCAGGACAGTCTGCAAGCTTCGATTACCGCCGCTGGAGCTGATCCTGACGGGAAGGTGAAGAAAGAATCGCCAGCGAAAGTCGCTTCCGAAGCGAATGTACACACAGACCCTGCCGACAGCATCGTGCAGGTTGAGAAATATCATATTGAGCTGCTGAAGGTAGAACCATGCCTTCCCGCGGCGAAACAGACAAGTGATCAGCACGATGAACCGGTTGTGGAGTATTTGTCGGAAAGTTTAGTCAAAGCAGAATCGAACGATAGTTTAAATTATGACGATGATAACGGTGACGTGCTAGAAGACACTGAACCAGTACGGGAAGAGCCCACGACCGACGAAGACAAAGGCAAACAGAACAACACACCACAGCGGCGCAAGAGGGAAAACCGGCCCCGGGAGGAGGATGAAGAGCTGCTGCGCAAACATTTCCATCTGGGGTGTGAAAAGTGCCCCTTCAAGGCGGAAACGGTGGCGGCACTGTTTCACCATTACCGCCTGGACCACCAAACACCCGGCTACGTCGAGTGTTGCAATCGCAAGTTTTTCCGGCGCGCACGGCTCCTCGAGCATCTGGGCGCACACTTGGGATCGATCGTGTGCGACGTGTGCGGCAAAGTGTTCCGGAACGTGTGCTCGCTCAATCTGCACAAGCTGGACCACGAGCAGCCGAAGCACGCGCGGCAGTACAAGTGCGAGCGGTGCAACTATTCCTTCCACAAGCTGTACCACCTGAAACAGCACCAGAAGCGCCACGAGCGGTTACGGTGCACCGTCTGCGATAAGGTGCTGGCCGGCGAGCAGGGGCTGAAGACGCACATGCAGAAAGTGCACGGCACGGACAACACACAGATCTGCCCCACCTGTGGCAAGGAGTTCCGCTGCCTGCTGGCCATGAAGCGGCATATCCGGGCGCACCTGGGCATCGTGACGGTCGAGCGGGTGCAGTGCGACCAGTGCGCGAAGTGGTTCGACAGCAAGCTGAACCTGCGCAACCATATCAAGGGCGTGCACGATGGGGCCGGCCCGATCCAGTGCGACGAGTGTCAGCACGTCAGCCCGAACCGGCGGGCACTGACGAACCATAAGCTGCGGACGCACGGCCGCAAGCAGACGTTTGAGTGCGAGCACTGCGGGAAGAAGCTGAACACGAAGCTCACGCTAAAGGAGCACATGGCCACGCATACGAACATTCCGCTCTACTCGTGCGAGTTCTGCGGCATCACGTTCAATTCCAACGCGAACAAGTACGTGCACCGGAAGAGCAAACATCCGCAGGAATGGGAAGCGATGATGCAGCAAAAGCTCATGCAGCGAATGGGTCCAGCTGCAATATTGTCGGAATCATTTCGGTACGCAAAAATGAGTGAAAGATGTCGCCTTTGTCTGGGAAGTTTATCGTCCACCGGGCCGAAGTTATCGATACGCGACGCTGAATTTCAAGAGGAGCTAAAAacggtgtttcatttcgatATAATCCACGATACGGCGCTTCCGGAACACGTGTGCAATGAATGCAGAAGTACCGTGTCTTACTGCCACTCGTACTGCCTACAGGTTCAGGCCAATCAGCTCCAACTGCTCGGGGAGGCGAACGAAAATGTCCTTAAGCCGGTGGAAAATGTTATGGTGGAATTACTAGTCGAAGAGGATGACTGTACCAAGACGGAAAAGCATTTACAGAAGGAAGAGCTGGCTGTGAATCAAGAGGCAACTATGTGTTTGGAGGACCGGGAAGGATTGAGCGTAGACGAGGATTGCGTTCGAGGGAAGAACGATAAACAGCGACGACGAGCGTGCaaaagtattaaaaacaaGCCCGATCTACAAAAAGAGACCGAAAATCAGGACACGTCCTCAAAAGAATTATCACAAGCTAAACAGCTAGAGAACGATAAAATCATAACCCAATTCTTCACTCTAGAGTGTGAGATCTGTGCGGCAACGGCGGAAAGCTTCGTCCAGCTGCTGGACCACTACCGAACCGCGCACAAAACGAAAGGTTACGTGCGATGCTGCGGTAAGCAGTTCTTTCGTCGATACATTCTGGTAGATCACATTGCAGCGCACCGCGGCACGATACGGTGCGAAATTTGCCATAAAACGTACAAAACGAAACGCTACCTGGCGCTACACTTTGCCAAAAGTCACAGCGGCGAAACGGATCGACCGTTCAAGTGCGGCAAGTGTCACGTGTCCTACCCGAAGCAGTATTTGCTGCGGGCGCACGAACTGATGCACGTCCAGCAGCAGTGCCATATCTGCGAGAAGGTTCTCTCCAACACTCAGTCGCTGAAGGTGCACATCGCCCAGATGCACGGCGGCGATGGGCATCACATCTGTGACACATGCGGGAAGGTGTTCCGCACCAAACCGGCCATGGAGCGGCACATCAACGAGCATATGGGGGTGGACGTGGTAGAACGGCTGCAGTGCGACCACTGCCAGAAATGGTTCAGCGGGAAGTACAACCTGCGCAAGCACGTGCGCTTTATGCACCTGGAGGGCGGGCAGGTATTTCGGTGCGAGCTATGCCCGCACGAAAGCCCCAATAGTCGGGCACTGGCGAACCACAAGCTGCGAGTGCACGTGGAGGAACGGTTTGAGTGCGAGTACTGTGGCAAGCGGTTCAAACGGCGGCCCAACTTGCGGGAACACATCGCATCGCACACGAACATGCCGCTTTACTCGTGCGAGATATGCCAGAATCGAACGTTCAACTCGAAGGCCAACTACTTTACGCATCGAAAACACAAGCATCCGCAGGAATGGGAGGCTCAGAAGCGGTTGCGGACGGAGCGGGAAATgagcaaaaattaa
Protein Sequence: MKNEPQTCRLCLRSSFRGRKIAISNGDFQQKLKAVFSFDIAPAENLPADACRGCRETVEQFYEYSEKVRANQDSLQASITAAGADPDGKVKKESPAKVASEANVHTDPADSIVQVEKYHIELLKVEPCLPAAKQTSDQHDEPVVEYLSESLVKAESNDSLNYDDDNGDVLEDTEPVREEPTTDEDKGKQNNTPQRRKRENRPREEDEELLRKHFHLGCEKCPFKAETVAALFHHYRLDHQTPGYVECCNRKFFRRARLLEHLGAHLGSIVCDVCGKVFRNVCSLNLHKLDHEQPKHARQYKCERCNYSFHKLYHLKQHQKRHERLRCTVCDKVLAGEQGLKTHMQKVHGTDNTQICPTCGKEFRCLLAMKRHIRAHLGIVTVERVQCDQCAKWFDSKLNLRNHIKGVHDGAGPIQCDECQHVSPNRRALTNHKLRTHGRKQTFECEHCGKKLNTKLTLKEHMATHTNIPLYSCEFCGITFNSNANKYVHRKSKHPQEWEAMMQQKLMQRMGPAAILSESFRYAKMSERCRLCLGSLSSTGPKLSIRDAEFQEELKTVFHFDIIHDTALPEHVCNECRSTVSYCHSYCLQVQANQLQLLGEANENVLKPVENVMVELLVEEDDCTKTEKHLQKEELAVNQEATMCLEDREGLSVDEDCVRGKNDKQRRRACKSIKNKPDLQKETENQDTSSKELSQAKQLENDKIITQFFTLECEICAATAESFVQLLDHYRTAHKTKGYVRCCGKQFFRRYILVDHIAAHRGTIRCEICHKTYKTKRYLALHFAKSHSGETDRPFKCGKCHVSYPKQYLLRAHELMHVQQQCHICEKVLSNTQSLKVHIAQMHGGDGHHICDTCGKVFRTKPAMERHINEHMGVDVVERLQCDHCQKWFSGKYNLRKHVRFMHLEGGQVFRCELCPHESPNSRALANHKLRVHVEERFECEYCGKRFKRRPNLREHIASHTNMPLYSCEICQNRTFNSKANYFTHRKHKHPQEWEAQKRLRTEREMSKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -